CN103976891A - Composition for facial repair and preparation method thereof - Google Patents
Composition for facial repair and preparation method thereof Download PDFInfo
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- CN103976891A CN103976891A CN201410171066.7A CN201410171066A CN103976891A CN 103976891 A CN103976891 A CN 103976891A CN 201410171066 A CN201410171066 A CN 201410171066A CN 103976891 A CN103976891 A CN 103976891A
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Abstract
The invention provides a composition for facial repair. The composition is composed of the following components in percentage by weight: 0.01 to 1% of EGF freeze-dried powder, 0.01 to 5% of SOD, 0.1 to 5% of active peptide, 0.01 to 2% of allantoin, and the balance being water; wherein the active components are all individually buried in liposome or covered by nano microcapsules before the mixing. The active effective components of the composition are individually buried in or covered by transfer vectors. Then the active effective components are transported to the corium layer or shallow corium layer by the transfer vectors to promote the cell metabolism, growth, proliferation, and differentiation, remove the free radicals and harmful substances, and improve the skin problems such as dull and yellow skin color, dryness, wrinkles, skin allergy, and the like.
Description
Technical field
The present invention relates to cosmetics technical field, be specifically related to a kind of compositions of repairing for face, and the preparation method of said composition.
Background technology
Skin is the outermost organ of human body; it covers whole body; by three layers of epidermises, corium, subcutaneous tissue, formed; protection human body avoids being subject to extraneous mechanicalness, physical property, chemical or physiological invasion and attack; keeping stablizing of human internal environment; skin also participates in the metabolic process of human body simultaneously, expresses especially people's beauty treatment and old and feeble sign.
And skin impaired have a very many factors, there are extraneous physical factor, inherited genetic factors, biological factor, health factor, iatrogenic factors etc., as can making skin, excessive ultraviolet radiation there is irreversible damage, aging and become coarse, pigmentation etc., supercool, overheated, excessive mechanical irritation all can exert an influence to skin simultaneously, makes skin impaired.Under the comprehensive function of various factors, caused the hydropenia of skin, the problem such as dark yellow, lax, responsive, old and feeble, obscure, caused skin can't bear the heavy load, become very fragile.
Cosmetics kind is in the market too much, composition not clear; in addition consumer's improper use; be easy to cause the damage of skin; as the product of excessive use destratum corneum; and the result that horny layer is excessively peeled off can make horny layer lose protectiveness, not only cannot resist the injury (as ultraviolet, the temperature difference etc.) of physical factor; also cannot resist the chemokines being covered with in air, skin is as easy as rolling off a log because of weak sensitization.Dermal layer of the skin cell metabolism is vigorous, free circulation of the blood, when it is subject to the damage that free radical, heavy metal, nutrient substance are under-supply etc., when especially dermal layer of the skin damages, general nutrient substance is because the problems such as molecular size range are difficult to arrive by skin surface the reparation that skin corium carries out skin.
Summary of the invention
Technical problem to be solved by this invention is for above the deficiencies in the prior art, a kind of compositions of repairing for face is provided, the active effective ingredient of said composition is got up with transport vehicle parcel or embedding separately respectively, transportation by transport vehicle arrives skin corium or shallow skin corium, promote metabolism, growth, the proliferation and differentiation of cell, remove free radical, harmful substance etc., improve the problems such as dim mute, dark yellow, the hydropenia of skin, aging, sensitivity.
The technical solution adopted in the present invention is:
A kind of compositions of repairing for face, said composition comprises each component of following mass percent: EGF lyophilized powder 0.01-1%, SOD0.01-5%, bioactive peptide 0.1-5%, allantoin 0.01-2%, surplus is water, active component (EGF lyophilized powder, SOD, bioactive peptide, allantoin) equal independent liposome embedded or capsule of nano parcel before mixing wherein, thus preparation have ultra micro capsule structure can Transdermal absorption repairing activity material.
Described bioactive peptide is a kind of in Argireline, algal active peptide, micromolecule collagen polypeptide.
EGF lyophilized powder can be repaired horny layer, strengthens the thickness of skin, to the decortication thing of the middle appearance that makes in the past to apply some make up and stratum corneum gets thinner, red blood streak that bad composition causes expose, fragile, easily rubescent, the phenomenon such as itch has super good repair.But EGF lyophilized powder can not directly be applied in client's face, after it need to being mixed with solvent, re-use.
SOD plays dual function to skin, on the one hand it can to promote that collagen protein forms appropriately crosslinked; On the other hand, it can be used as effective free radical scavenger, prevents skin aging, keeps submissive smooth, perpetual youth.SOD can also stablize collagen protein and elastin laminin, thereby makes skin high resilience.Due to ultraviolet injury, human skin can accelerate old and feeble and wrinkling, and SOD can assist to protect skin to avoid ultraviolet damage; can effectively remove free radical; the generation of blocking-up elastoser, and suppress its activity, thus from inside, improve the health status of skin.Life-time service, can nourishes rough skin, reduces dermatosis and wrinkle.SOD removes the strongest effectively antioxidant of free radical, and its oxidation resistance is ascorbic 20 times, 50 times of vitamin E, and its removes specificity, the high efficiency of free radical, and other antioxidants are incomparable especially.Adhere to using SOD can be when dispelling free radical endocrine regulation, prevent that mottle from appearring in skin.
Bioactive peptide is from isolated active factorses of extraction such as animals and plants, by two above amino acid chains, close the protein polypeptide forming, the deep enough Skin Cell of this active polypeptide energy, supplement fast Skin Cell nutrient, directly activate and skin nutrition cell, reach the effect of deep layer reparation, promotion cellular metabolism, active cell vigor.
Allantoin can make cell proliferation so that epidermal area forms rapidly, reaches to repair skin, induce the fine and smooth effect of newborn Skin rejuvenation, makes chafing, anaphylaxis, Zou Wen and aging, be full of cracks obtain good reparation and recover normal effect.
We know, the increase of every kind of composition of cosmetics all likely changes certain physics or the chemical characteristic of whole system.The combinations of substances that the present invention takes the lead in these four kinds of the EGF lyophilized powders, SOD, bioactive peptide, allantoin to have a repair together, by rational proportioning between each material, make each material in said composition can bring into play well its effect, and synergism is good, thereby effectively realize metabolism, growth, the proliferation and differentiation that promotes cell, remove free radical, harmful substance etc., improve the problems such as dim mute, dark yellow, the hydropenia of skin, aging, sensitivity.
The product form of described compositions is cream frost or liniment or facial film or emulsion or toner/smoothing toner or cleansing milk.
The present invention also further provides the preparation method of above-mentioned compositions of repairing for face, it comprises the following steps: each raw material that takes recipe ingredient, EGF lyophilized powder, SOD, bioactive peptide, allantoin are all wrapped up with liposome embedded or capsule of nano separately, then be placed in 60-65 ℃ of water-bath constant temperature 30min, after water-bath finishes, each component is mixed, slowly stir and be naturally cooled to room temperature, obtaining the compositions of repairing for face.
The present invention more payes attention to the research of the Transdermal absorption of cosmetic industry composition, and the effective active composition that makes cosmetics is by skin, and arrives not same-action skin layer and bring into play various effects.Compared with prior art, the present invention has following remarkable advantage and beneficial effect:
(1) adopt liposome technology and capsule of nano technology, active component parcel or embedding are got up, by the transhipment of these transport vehicle, promote that active factors enters skin skin corium, at the bottom of promoting the growth, Differentiation, removing oxygen-derived free radicals, strengthening flesh of skin cell, strengthen the defensive ability/resistance ability of skin, thereby fundamentally repair skin, remove free radical and harmful substance, promote the formation of collagen fiber, reticular fiber, elastic fiber, regulate the generation of collagen protein, recover smooth, tender, the elasticity of skin;
(2) adopt Transdermal absorption movement system, particularly the horny layer of biomacromolecule material or high molecular polymer is through rate greatly to have improved active component, and transdermal transfer rate is high;
(3) adopt two kinds of technology of liposome technology and capsule of nano technology to realize the embedding to active component, than a kind of embedding techniques of independent use, embedding Du Genggao, embedding better effects if;
(4) active component is wrapped or embedding, keep apart with extraneous oxygen, dust particle etc., can reach the object of prolection composition, guarantee the stability of active component, prevent that it is oxidized, destruction etc., and each active component is parcel or embedding separately, avoided the probability of having an effect each other, system stability is good, than preventing oxidized prior art by adding antioxidant, do not need additionally adding of stable elements, cost is relatively lower;
(5) composition components that the present invention's face is repaired is simple, and rationally, cooperative effect is good for formula, and reparation effect is good.
The specific embodiment
Below in conjunction with embodiment, the present invention is further described in detail.Be noted that following illustrating is all exemplary, be intended to the invention provides further instruction.Except as otherwise noted, all Science and Technology terms that the present invention uses have the identical meanings of conventionally understanding with the technical field of the invention personnel.
Embodiment 1:
The present embodiment is for repairing equilibrium water, and its formula is:
Preparation process:
(1) with liposome difference embedding 0.02gEGF lyophilized powder and 0.02gSOD, obtain EGF liposome and SOD liposome, be then placed in 60 ℃ of water-bath constant temperature 30min;
(2) with capsule of nano, wrap up respectively 0.05g Argireline and 0.1g allantoin, obtain Argireline microcapsule and allantoin microcapsule, be then placed in 60 ℃ of water-bath constant temperature 30min;
(3) take aminoacid, glycerol, propylene glycol, hydroxyethyl-cellulose, add water appropriate, under stirring, be swelling to clear and bright, (1) is slowly added respectively in above-mentioned lysate with (2), then add essence, antiseptic (germall BP) to stir, supply water to 100.0g, must repair equilibrium water.
Embodiment 2:
The present embodiment is repair cream, and its formula is:
Preparation process:
(1) with liposome difference embedding 0.1gEGF lyophilized powder and 0.15gSOD, obtain EGF liposome and SOD liposome, be then placed in 60 ℃ of water-bath constant temperature 30min;
(2) with capsule of nano, wrap up respectively 0.2g algal active peptide and 0.2g allantoin, obtain algal active peptide microcapsule and allantoin microcapsule, be then placed in 60 ℃ of water-bath constant temperature 30min;
(3) oil phase raw material mixed and be heated to 70 ℃, water raw material is mixed and heated to 60 ℃, oil phase is added in water, (1) is added respectively in water with (2) simultaneously, stirring and emulsifying, adds essence and antiseptic to stir after cooling, obtain repair cream.
Embodiment 3:
The present embodiment is repair latex, and its formula is:
Preparation process:
(1) with liposome difference embedding 0.05gEGF and 0.15g micromolecule collagen polypeptide, obtain EGF liposome and micromolecule collagen polypeptide liposome, be then placed in 60 ℃ of water-bath constant temperature 30min;
(2) with capsule of nano, wrap up respectively 0.05gSOD and 0.15g allantoin, obtain SOD microcapsule and allantoin microcapsule, be then placed in 60 ℃ of water-bath constant temperature 30min;
(3) water raw material is mixed and heated to 65 ℃-70 ℃, oil phase raw material is mixed and be heated to 70 ℃-80 ℃ and make its fusing evenly, oil phase and water are added respectively in emulsion tank, (1) is added respectively in emulsion tank with (2) simultaneously, maintain 70 ℃, homogenizing 10min-30min, is cooled to 40 ℃ of left and right, add essence and antiseptic to stir, obtain repair latex.
Embodiment 4:
The present embodiment is for repairing facial film, and its formula is:
Preparation process:
(1) with liposome difference embedding 0.01gEGF and 0.01gSOD, obtain EGF liposome and SOD liposome, be then placed in 60 ℃ of water-bath constant temperature 30min;
(2) with capsule of nano, wrap up respectively 0.05g Argireline and 0.1g allantoin, obtain Argireline microcapsule and allantoin microcapsule, be then placed in 60 ℃ of water-bath constant temperature 30min;
(3) take hyaluronic acid, glycerol, propylene glycol, carboxymethyl cellulose, hydroxyethyl-cellulose, add water appropriate, under stirring, be swelling to clear and bright, (1) is slowly added respectively in above-mentioned lysate with (2), then add essence, antiseptic to stir, supply water to 100.0g, must repair facial film essence, then carry out fill, packing, obtain reparation facial film.
The raw material that embodiment is used, unless otherwise indicated, is and is applicable to the commercially available prod that cosmetics are used.
The above embodiment of the present invention is to explanation of the present invention and can not be for limiting the present invention, and the implication suitable with claims of the present invention and any change in scope, all should think to be included in the scope of claims.
Claims (4)
1. a compositions of repairing for face, it is characterized in that comprising each component of following mass percent: EGF lyophilized powder 0.01-1%, SOD0.01-5%, bioactive peptide 0.1-5%, allantoin 0.01-2%, surplus is water, wherein active component equal independent liposome embedded or capsule of nano parcel before mixing.
2. a kind of compositions of repairing for face according to claim 1, is characterized in that: described bioactive peptide is a kind of in Argireline, algal active peptide, micromolecule collagen polypeptide.
3. a kind of compositions of repairing for face according to claim 1, is characterized in that: described compositions is cream frost or liniment or facial film or emulsion or toner/smoothing toner or cleansing milk.
4. the preparation method of a kind of compositions of repairing for face described in the arbitrary claim of claim 1-3, it is characterized in that comprising the following steps: each raw material that takes recipe ingredient, EGF lyophilized powder, SOD, bioactive peptide, allantoin are all wrapped up with liposome embedded or capsule of nano separately, then be placed in 60-65 ℃ of water-bath constant temperature 30min, after water-bath finishes, each component is mixed, slowly stir and be naturally cooled to room temperature, obtaining the compositions of repairing for face.
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| CN201410171066.7A CN103976891B (en) | 2014-04-25 | 2014-04-25 | A kind of composition and method of making the same repaired for face |
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| CN201410171066.7A CN103976891B (en) | 2014-04-25 | 2014-04-25 | A kind of composition and method of making the same repaired for face |
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| CN103976891B CN103976891B (en) | 2016-01-27 |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104337734A (en) * | 2014-10-22 | 2015-02-11 | 广东幸美化妆品股份有限公司 | Restoring facial cleanser and preparation method thereof |
| CN105310945A (en) * | 2015-12-15 | 2016-02-10 | 钟苏 | Skin repair mask cream and preparation method thereof |
| CN105560160A (en) * | 2016-03-16 | 2016-05-11 | 广州市科玮生物技术有限公司 | Facial mask essence containing chitosan and preparation method thereof |
| CN106265130A (en) * | 2016-09-29 | 2017-01-04 | 防城港市港口区高创信息技术有限公司 | A kind of compositions for skin repair and preparation method thereof |
| CN107213080A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of aloe additive and preparation method thereof |
| CN107213044A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of white birch cosmetic composition and preparation method thereof |
| CN107213043A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of lemonene peach additive and preparation method thereof |
| CN107213047A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of hairyvein agrimony composition and preparation method thereof |
| CN107213045A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of elder composition and preparation method thereof |
| CN107213046A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of alkanet cosmetic composition and preparation method thereof |
| CN112006964A (en) * | 2019-05-31 | 2020-12-01 | 广州北斗生物科技有限公司 | Preparation method and application of microcapsule-coated polypeptide substance with skin care effect |
| CN112675046A (en) * | 2020-12-31 | 2021-04-20 | 华南理工大学 | Almond polypeptide hair care nano micelle and preparation method thereof |
| CN117427201A (en) * | 2023-12-20 | 2024-01-23 | 辽宁帝东医药生物工程有限公司 | Antibacterial wound dressing capable of promoting healing |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112828A (en) * | 1994-05-30 | 1995-12-06 | 乌力吉 | Face care cream containing extract of Chinese soft shelled turtle and snail |
| CN1875916A (en) * | 2006-04-27 | 2006-12-13 | 广州市采诗化妆品有限公司 | A whitening moisturizing composition |
| CN102366383A (en) * | 2011-09-26 | 2012-03-07 | 佛山科学技术学院 | Marine organism functional cosmetic for nourishing skin around eyes |
-
2014
- 2014-04-25 CN CN201410171066.7A patent/CN103976891B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112828A (en) * | 1994-05-30 | 1995-12-06 | 乌力吉 | Face care cream containing extract of Chinese soft shelled turtle and snail |
| CN1875916A (en) * | 2006-04-27 | 2006-12-13 | 广州市采诗化妆品有限公司 | A whitening moisturizing composition |
| CN102366383A (en) * | 2011-09-26 | 2012-03-07 | 佛山科学技术学院 | Marine organism functional cosmetic for nourishing skin around eyes |
Non-Patent Citations (1)
| Title |
|---|
| 马振友 等: "《皮肤美容化妆品制剂手册》", 31 March 2004, 中医古籍出版社 * |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104337734A (en) * | 2014-10-22 | 2015-02-11 | 广东幸美化妆品股份有限公司 | Restoring facial cleanser and preparation method thereof |
| CN105310945A (en) * | 2015-12-15 | 2016-02-10 | 钟苏 | Skin repair mask cream and preparation method thereof |
| CN105560160A (en) * | 2016-03-16 | 2016-05-11 | 广州市科玮生物技术有限公司 | Facial mask essence containing chitosan and preparation method thereof |
| CN105560160B (en) * | 2016-03-16 | 2018-08-17 | 广州市科玮生物技术有限公司 | A kind of facial mask liquid and preparation method thereof containing chitosan |
| CN106265130A (en) * | 2016-09-29 | 2017-01-04 | 防城港市港口区高创信息技术有限公司 | A kind of compositions for skin repair and preparation method thereof |
| CN107213045A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of elder composition and preparation method thereof |
| CN107213043A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of lemonene peach additive and preparation method thereof |
| CN107213047A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of hairyvein agrimony composition and preparation method thereof |
| CN107213044A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of white birch cosmetic composition and preparation method thereof |
| CN107213046A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of alkanet cosmetic composition and preparation method thereof |
| CN107213080A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of aloe additive and preparation method thereof |
| CN112006964A (en) * | 2019-05-31 | 2020-12-01 | 广州北斗生物科技有限公司 | Preparation method and application of microcapsule-coated polypeptide substance with skin care effect |
| CN112675046A (en) * | 2020-12-31 | 2021-04-20 | 华南理工大学 | Almond polypeptide hair care nano micelle and preparation method thereof |
| CN112675046B (en) * | 2020-12-31 | 2022-02-15 | 华南理工大学 | Almond polypeptide hair care nano micelle and preparation method thereof |
| CN117427201A (en) * | 2023-12-20 | 2024-01-23 | 辽宁帝东医药生物工程有限公司 | Antibacterial wound dressing capable of promoting healing |
| CN117427201B (en) * | 2023-12-20 | 2024-03-15 | 辽宁帝东医药生物工程有限公司 | Antibacterial wound dressing capable of promoting healing |
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