CN103954479B - A kind of sampling reagent adding device eliminating reagent residual - Google Patents
A kind of sampling reagent adding device eliminating reagent residual Download PDFInfo
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- CN103954479B CN103954479B CN201410145696.7A CN201410145696A CN103954479B CN 103954479 B CN103954479 B CN 103954479B CN 201410145696 A CN201410145696 A CN 201410145696A CN 103954479 B CN103954479 B CN 103954479B
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Abstract
The present invention relates to the improved device of a kind of reagent adding device, a kind of sampling reagent adding device eliminating reagent residual, including quantitative capillary tube (1) from bottom to top, installing rack (4), kit box (2) and piston (3), quantitative capillary tube (1) is fixed on the bottom of kit box (2) by shaft-like installing rack (4)；The kit box (2) cylindrical center in opening upwards arranges vertical newel (2c), top is needle point, offers several fluid holes (2a) around base plate (2b) newel (2c) of cylinder interior；The cylinder that kit box (2) is open above inserts piston (3)；Agent bin (3a) is upwards offered in the bottom of piston (3), the sealer (3b) of bottom encapsulate reagent；Several fluid holes (2a) on base plate (2b) are positioned at the opening range of reaction cup or reaction tube.It is encapsulated in the reagent in piston agent bin to flow downward out from the breach of sealer, from the fluid hole of the surrounding of newel all, flow in reaction cup or reaction tube up hill and dale, accurate test result can be obtained.
Description
Technical field
The present invention relates to the improved device of a kind of reagent adding device, the improved device of especially a kind of integrated quantitative sampling reagent adding device.
Background technology
Current detection present situation, in reaction cup, first add diluent (A) 500uL, then pipettor sampling (B) 2uL is used, after sampling, sample is added in reaction cup, shake reaction cup makes sample and diluent mixing, it is necessary to detect after changing pipettor addition 50tlL reagent (C) mixing of 50tlL or 100tlL range again.Whole operating process at least needs to use the pipettor of two different ranges, and operating process is more complicated, relatively big particularly with below 2uL sample error, relatively costly.
For above phenomenon, in recent years the patent No. 201010539091.8 " a kind of integrated quantitative sampling reagent adding device " it is proposed, the patent No. 201120293289.2 " Integral sample collecting injection device " and the patent No. 201220584650.1 " structure-improved of a kind of quantitative sampling reagent adding device ", basic structure is identical with function, disclose following structure, including quantitative capillary tube, support, kit box, piston and snap ring, it is characterized in that: quantitative capillary tube is assigned on support, support and kit box are integral type, support is positioned at one end of kit box, the kit box other end is equipped with piston；Agent bin in described piston is encapsulated reagent by sealer, and support afterbody has the taper pin offering centre bore；By pressing the piston sealer by the broken agent bin of the acupuncture of support afterbody, when continuing to press lower piston, the reagent in agent bin is flowed in reaction cup by the centre bore of support, completes quantitative reagent and adds reaction cup.
But known, the taper pin offering centre bore is coniform, and sealer is plastic sheeting, pin plastic sheeting when puncturing sealer uniformly tightly will not expand from small to large along needle point, and have and tear phenomenon, and hole can be torn, breach occur, now the reagent in agent bin can flow out from the notched slot torn.But, prior art reagent sole outlet is that the hole offered on needle point flows through in centre bore inflow reaction cup or reaction tube, therefore tear, from sealer, the reagent that gap and openning flow out and can flow into and be accumulated in the surrounding space of kit box and centre bore, it is cannot flow into centre bore from the hole needle point again, therefore random, it is impossible to the accumulation reagent residual known can have a strong impact on measuring accuracy.Especially, during test, the needle point of support is upward, accumulates the more impossible hole climbed into from lower to upper above needle point of reagent residual and flows out, and this disadvantage prior art cannot overcome.But the precision in order to improve test must change.
Summary of the invention
Present invention aims to above-mentioned the deficiencies in the prior art, it is provided that one can eliminate reagent residual, improve the quantitative sampling reagent adding device of measuring accuracy.
The purpose of the present invention is realized by following technical scheme.
A kind of sampling reagent adding device eliminating reagent residual, including quantitative capillary tube from bottom to top, installing rack, kit box and piston, it is characterised in that:
Described quantitative capillary tube is fixed on the bottom of kit box by shaft-like installing rack；
Kit box is the cylinder of opening upwards, and the central authorities at cylinder arrange vertical newel, and newel top is needle point, on the base plate of cylinder interior, offers several fluid holes around newel；
Inserting in the cylinder that kit box is open above can the cylindric piston of relative movement up and down；Agent bin is upwards offered in the bottom of piston, is encapsulated reagent by the sealer of bottom in agent bin；
At described kit box base plate bottom placing response cup or reaction tube, several fluid holes on base plate are positioned at the opening range of reaction cup or reaction tube.
Adopting the technical program, kit box is the cylinder of opening upwards, and the central authorities at cylinder arrange vertical newel, and newel top is needle point.Agent bin is upwards offered in the bottom of piston, is encapsulated reagent by the sealer of bottom in agent bin；When pressing piston, piston moves down, the needle point at newel top can puncture sealer, packed reagent can flow downward out from the breach of sealer, flow into the appearance of newel, trickling space to kit box, between cylinder and newel, owing to offering several fluid holes around newel, reagent just flows downward out kit box base plate from these fluid holes.Again due to the opening range of reaction cup or reaction tube " several fluid holes on base plate be positioned at ", therefore these reagent just all flow in reaction cup or reaction tube, reagent under self gravitation effect can all, clean from fluid hole stream up hill and dale, avoid the reagent that prior art accumulates around newel and become the drawback that residual liquid cannot flow out, can ensure that correctly, exactly with diluent, and the sample gathered by quantitative capillary tube precisely mixes, obtain accurate test result.
Further, described newel is hollow pipe, and newel top needle point is offered through hole connection hollow pipe.
Further, configuring annular snap ring between described kit box and described piston, described snap ring is step-like, and first half inwall mates with the cylinder outer wall of kit box, and latter half inwall mates with piston outer wall.
Further, top tapered needle surface and tube wall appearance at described newel offer groove, and groove direction is from up to down.
Further, the top tapered needle point of described newel and tube wall are the multi-disc vertically radial laminated structure stretched out.
Beneficial effects of the present invention, determined by the construction features of the present invention, it is encapsulated in the reagent in piston agent bin to flow downward out from the breach of sealer, flow into the appearance of newel, trickling is to kit box, the fluid hole offered from the surrounding of newel all, flow in reaction cup or reaction tube up hill and dale, can obtain accurate test result.Revolutionize that remaining reagent amount in prior art is uncontrollable, can not survey, can not the disadvantage of emptying, and the method changed is simple, feasible, reliable results.
Accompanying drawing explanation
Fig. 1 is the sampling reagent adding device one embodiment that the present invention eliminates reagent residual, the structure configuration map of bottom placing response cup test tube；
Fig. 2 is the sampling reagent adding device another embodiment that the present invention eliminates reagent residual, configures the structure configuration map of snap ring between kit box and piston；
Fig. 3 is the sampling reagent adding device another embodiment that the present invention eliminates reagent residual, and newel is hollow pipe, and top needle point is offered the structure chart of through hole connection hollow pipe；
Fig. 4 is the structure chart of a kind of quantitative sampling reagent adding device of prior art.
In figure:
1 is quantitative capillary tube, 2 to be kit box, 2a be fluid holes, 2b to be base plate, 2c be newel, 3 it is piston, 3a is agent bin, 3b to be sealer, 4 to be installing rack, 4a be needle points, 4b be pipe, 5 is snap ring.
Detailed description of the invention
The structure of the present invention is further described below in conjunction with accompanying drawing.
A kind of sampling reagent adding device eliminating reagent residual, including quantitative capillary tube 1 from bottom to top, installing rack 4, kit box 2 and piston 3,
Described quantitative capillary tube 1 is fixed on the bottom of kit box 2 by shaft-like installing rack 4；
The kit box 2 cylinder in opening upwards, it is needle point that the central authorities at cylinder arrange vertical newel 2c, newel 2c top, on the base plate 2b of cylinder interior, offers several fluid holes 2a around newel 2c；
Inserting in the cylinder that kit box 2 is open above can the cylindric piston 3 of relative movement up and down；The bottom of piston 3 is upwards offered in agent bin 3a, agent bin 3a and is encapsulated reagent by the sealer 3b of bottom；
At described kit box 2 base plate 2b bottom placing response cup or reaction tube, several fluid holes 2a on base plate 2b is positioned at the opening range of reaction cup or reaction tube.
Described newel 2c is hollow pipe, and newel 2c top needle point is offered through hole connection hollow pipe.Offering on kit box 2 base plate 2b on the basis of fluid hole 2a, then to allow newel 2c be hollow pipe, top needle point is offered through hole connection hollow pipe, dual trickling reagent can accelerate to flow into the speed of reaction cup or reaction tube.
Configuring annular snap ring 5 between described kit box 2 and described piston 3, described snap ring 5 is in step-like, and first half inwall mates with the cylinder outer wall of kit box 2, and latter half inwall mates with piston 3 outer wall.The structure of member-retaining portion prior art sampling reagent adding device, available existing parts, reduce the cost of remodeling, the remodeling of advantageous elements prior art products.
Top tapered needle surface and tube wall appearance at described newel 2c offer groove, and groove direction is from up to down.Reagent in agent bin can trickle downwards along groove, it can be ensured that in the agent bin 3a of piston 3, reagent solution flows out from agent bin, and stream is clean.
The top tapered needle point of described newel 2c and tube wall are the multi-disc vertically radial laminated structure stretched out.Described laminated structure can be four, six etc., just as heat radiation lamellar configuration, it is easier to scratch sealer, allows the reagent in agent bin flow out.
Claims (4)
1. eliminate a sampling reagent adding device for reagent residual, including quantitative capillary tube (1) from bottom to top, installing rack (4), kit box (2) and piston (3), it is characterised in that:
Described quantitative capillary tube (1) is fixed on the bottom of kit box (2) by shaft-like installing rack (4)；
The kit box (2) cylinder in opening upwards, central authorities at cylinder arrange vertical newel (2c), newel (2c) top is needle point, on the base plate (2b) of cylinder interior, around newel (2c), offer several fluid holes (2a)；
Inserting in the cylinder that kit box (2) is open above can the cylindric piston (3) of relative movement up and down；Agent bin (3a) is upwards offered in the bottom of piston (3), has reagent in agent bin (3a), and described reagent is encapsulated by the sealer (3b) being positioned at agent bin (3a) bottom；
Several fluid holes (2a) on described kit box (2) base plate (2b) bottom placing response cup or reaction tube, base plate (2b) are positioned at the opening range of reaction cup or reaction tube.
2. eliminate the sampling reagent adding device of reagent residual according to claim 1, it is characterized in that configuring annular snap ring (5) between described kit box (2) and described piston (3), described snap ring (5) is in step-like, first half inwall mates with the cylinder outer wall of kit box (2), and latter half inwall mates with piston (3) outer wall.
3. eliminate the sampling reagent adding device of reagent residual according to claim 1, it is characterised in that top tapered needle surface and tube wall appearance at described newel (2c) offer groove, and groove direction is from up to down.
4. eliminate the sampling reagent adding device of reagent residual according to claim 1, it is characterised in that the top tapered needle point of described newel (2c) and tube wall are the multi-disc vertically radial laminated structure stretched out.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410145696.7A CN103954479B (en) | 2014-04-11 | 2014-04-11 | A kind of sampling reagent adding device eliminating reagent residual |
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| CN201410145696.7A CN103954479B (en) | 2014-04-11 | 2014-04-11 | A kind of sampling reagent adding device eliminating reagent residual |
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| CN103954479A CN103954479A (en) | 2014-07-30 |
| CN103954479B true CN103954479B (en) | 2016-07-06 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104502150B (en) * | 2014-12-16 | 2017-01-04 | 武汉海王新能源工程技术有限公司 | Used in nuclear power station radioactive liquid sample sampler and sampling method |
| CN107144460A (en) * | 2017-06-23 | 2017-09-08 | 张雪峰 | Just sample processor |
| CN108414263A (en) * | 2018-05-04 | 2018-08-17 | 上海透景诊断科技有限公司 | Fecal sample integral collecting device and method |
| CN109925966A (en) * | 2019-04-01 | 2019-06-25 | 丹娜（天津）生物科技有限公司 | A kind of filling of reagent and reaction unit |
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| US5307696A (en) * | 1991-03-25 | 1994-05-03 | Cogema-Compagnie Generale Des Matieres Nucleires | Liquid sampling head having a removable needle body immersed in a cavity |
| CN1293950A (en) * | 1999-10-20 | 2001-05-09 | 吴振东 | High-speed pneumatically osmotic composite cotton swab for medical purpose or daily use |
| CN102072949A (en) * | 2010-11-11 | 2011-05-25 | 郝书顺 | Integrated quantitative sampling and reagent adding device |
| CN202204706U (en) * | 2011-08-12 | 2012-04-25 | 石家庄禾柏生物技术股份有限公司 | Integral sample collecting injection device |
| CN202903768U (en) * | 2012-11-07 | 2013-04-24 | 上海奥普生物医药有限公司 | Improved structure of quantitative sampling reagent feed device |
| CN203132865U (en) * | 2012-12-25 | 2013-08-14 | 南京普朗医用设备有限公司 | Puncturing piston type sample feeding and sampling device |
| CN204008218U (en) * | 2014-04-11 | 2014-12-10 | 上海地慧光电科技有限公司 | A kind of solid pillar sampling reagent adding device |
-
2014
- 2014-04-11 CN CN201410145696.7A patent/CN103954479B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5307696A (en) * | 1991-03-25 | 1994-05-03 | Cogema-Compagnie Generale Des Matieres Nucleires | Liquid sampling head having a removable needle body immersed in a cavity |
| CN1293950A (en) * | 1999-10-20 | 2001-05-09 | 吴振东 | High-speed pneumatically osmotic composite cotton swab for medical purpose or daily use |
| CN102072949A (en) * | 2010-11-11 | 2011-05-25 | 郝书顺 | Integrated quantitative sampling and reagent adding device |
| CN202204706U (en) * | 2011-08-12 | 2012-04-25 | 石家庄禾柏生物技术股份有限公司 | Integral sample collecting injection device |
| CN202903768U (en) * | 2012-11-07 | 2013-04-24 | 上海奥普生物医药有限公司 | Improved structure of quantitative sampling reagent feed device |
| CN203132865U (en) * | 2012-12-25 | 2013-08-14 | 南京普朗医用设备有限公司 | Puncturing piston type sample feeding and sampling device |
| CN204008218U (en) * | 2014-04-11 | 2014-12-10 | 上海地慧光电科技有限公司 | A kind of solid pillar sampling reagent adding device |
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Effective date of registration: 20180321 Address after: No. 33, highway 4633, Pudong New Area Academy of Shanghai, Shanghai Patentee after: Shanghai Wangxin Bean Product Apparatus Co., Ltd. Address before: 200237, Shanghai, Minhang District Hongmei South Road, No. 1755, a layer of AB10 room Patentee before: SHANGHAI DIHUI PHOTOELECTRIC TECHNOLOGY CO., LTD. |