CN103948860B - A kind of Chinese medicine composition treating cyclomastopathy and preparation method thereof - Google Patents

Abstract

The present invention relates to a kind of Chinese medicine composition treating cyclomastopathy, be made up of according to weight fraction following components: Radix Bupleuri (vinegar-fried) 3 10 parts, Pericarpium Citri Reticulatae 3 10 parts, Fructus Citri Sarcodactylis 3 10 parts, Exocarpium Citri Grandis 3 10 parts, Rhizoma Curcumae 3 10 parts, the Radix Aucklandiae 3 10 parts, Radix Curcumae 6 12 parts, Cortex Moutan 6 12 parts, Herba Menthae 3 10 parts, Herba Leonuri 10 20 parts, Radix Paeoniae Rubra 5 15 parts, Herba Taraxaci 10 30 parts, 3 10 parts of Radix Glycyrrhizae.The Chinese medicine composition for the treatment of cyclomastopathy of the present invention, formulated according to theory of Chinese medical science, compatibility is reasonable, and each taste Chinese medicine combines according to monarch, plays maximum drug effect, and Chinese medicine preparation, toxic and side effects is little, low cost.

Description

A kind of Chinese medicine composition treating cyclomastopathy and preparation method thereof

Technical field

The present invention relates to traditional Chinese medicine field, particularly to a kind of Chinese drug-treated group treating cyclomastopathy Compound and preparation method thereof.

Background technology

Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and breast lobule Degeneration structurally and the growth of Progressive symmetric erythrokeratodermia connective tissue, its pathogenic factor is mainly Owing to endocrine hormone is lacked of proper care.Clinical manifestation mainly has: 1. mastalgia, is often distending pain or thorn Bitterly, can involve one or both sides breast, lay particular stress on side common, pain severe patient can not be touched, Even affect daily life and work.Pain based on lump in breast at, also can to Ipsilateral axillary fossa, The breast side of body or the radiation of shoulder back；Some then shows as sore nipples or itches.Mastalgia is often in menstruation Front a couple of days occurs or increases the weight of, and after passing through, pain substantially alleviates or disappears；Pain also can become with emotion Change and fluctuate.This pain relevant with menstrual cycle and emotion changes is that cyclomastopathy is clinical The main feature of performance.2. lump in breast, lump can be sent out in one side or bilateral breast, single Or multiple, it is apt to occur in the outside upper quadrant of breast, is also found in other quadrants.Lump shape has tile Shape, nodositas, streak, graininess etc., be wherein common with sheet bulk.Lump border is not Substantially, quality is medium or the most tough, movable good, with surrounding tissue without adhesion, often has tenderness. Tumor size differs, and little person is big as foxtail millet grain, and big person can exceed 3～4cm.Lump in breast also has The feature changed with menstrual cycle, the moon, premenstrual lump increased hardening, lump contracting after menstrual onset Little deliquescing.3. nipple discharge, small number of patients may occur in which nipple discharge, for spontaneous discharge, also has Few person extrude have courageous and upright discharge or milky to overflow seen from nipple body overflows, olive drab(O．D) or brown are starched Fluidity discharge.4. menoxenia, this patient is irregular before and after double can seeing menstruation, measures less or color Light, dysmenorrhea can be accompanied.5. feelings will changes, and patient's normal emotion will is smooth or susceptible to lose temper due to restlessness, gives birth to whenever Gas, psychentonia or tired postemphasis.

Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the head of mastopathy Position.Tradition thinks that it is to congeal into core institute due to depressed rage impairing the liver, worry impairing spleen, qi stagnation blood stasis, expectorant Causing, Chinese medicine is referred to as " nodules of the breast ".The cause of disease: 1. emotional factors: feelings will is not smooth, strongly fragrant long wound Liver, causes depression and stagnation of QI, pents up in breast stomach network, and meridian and vessels obstruction is obstructed, the most then stagnation of QI and blood may bring about pain, Heavy then stagnation of liver-QI QI and blood week loss degree, the stagnation of QI, expectorant become silted up, blood stasis lump formation due to accumulation of pathogens and form cyclomastopathy. 2. dietary factor: addiction to uncooked and cold food, delicious food, impairing the spleen and stomach, spleen fortune is lost to be good for and is then given birth to wet poly-expectorant.Expectorant Wet heresy viscous, easy air resister, stagnation of Qi and phelgm, it is then nodules of the breast that meridians block.The oldest tired interior Wound: exhaustion due to sexual indulgence, excessive fatigue, consumption hinders vigour；Kidney is the dirty of store essential substances, relies the taste day after tomorrow to be supported, With the passing of time, taste are wound to impairment caused by overstrain, the most then kidney benefit is empty, are difficult to fill and support punching and appoint, Chong and Ren channel disorder and lactogenesis Addiction.

Summary of the invention

For defect present in prior art, it is an object of the invention to provide one and treat breast The Chinese medicine composition of gland hypertrophy.

Technical scheme is as follows:

A kind of Chinese medicine composition treating cyclomastopathy, by following components according to weight fraction group Become:

Radix Bupleuri (vinegar-fried) 3-10 part, Pericarpium Citri Reticulatae 3-10 part, Fructus Citri Sarcodactylis 3-10 part, Exocarpium Citri Grandis 3-10 Part, Rhizoma Curcumae 3-10 part, Radix Aucklandiae 3-10 part, Radix Curcumae 6-12 part, Cortex Moutan 6-12 part, Herba Menthae 3-10 part, Herba Leonuri 10-20 part, Radix Paeoniae Rubra 5-15 part, Herba Taraxaci 10-30 part, Radix Glycyrrhizae 3-10 Part.

On the basis of such scheme, the Chinese medicine composition for the treatment of cyclomastopathy is pressed by following components Form according to weight fraction:

Radix Bupleuri (vinegar-fried) 7 parts, Pericarpium Citri Reticulatae 7 parts, Fructus Citri Sarcodactylis 7 parts, Exocarpium Citri Grandis 7 parts, Rhizoma Curcumae 7 Part, the Radix Aucklandiae 7 parts, Radix Curcumae 9 parts, Cortex Moutan 9 parts, Herba Menthae 7 parts, Herba Leonuri 15 parts, red Chinese herbaceous peony 10 parts, Herba Taraxaci 20 parts, 7 parts of Radix Glycyrrhizae.

A kind of method of Chinese medicine composition preparing treatment cyclomastopathy as above is concrete Preparation process is as follows:

(1) weigh each component in compositions according to quantity, utilize warm water to wash the impurity on surface；

(2) composition powder is broken to 500 mesh；

(3) compositions after pulverizing joins in 1000 parts of water immersion 30min, post-cooked Boiling 20min；

(4) cooled and filtered, concentrates the filtrate to 300 parts, and filtering residue is dried.

In the Chinese medicine composition for the treatment of cyclomastopathy of the present invention, Rhizoma Curcumae promoting the circulation of QI to relieve pain, broken Blood and dissolving stasis；Herba Leonuri blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema, heat-clearing and toxic substances removing；Cortex Moutan clearing away heat and cooling blood, work Blood dissipating blood stasis；Radix Paeoniae Rubra clearing away heat and cooling blood, stasis-dispelling and pain-killing, purging liver-fire；Herba Taraxaci heat-clearing and toxic substances removing, disappear Carbuncle eliminating stagnation；Five medicines are ministerial drug altogether；Pericarpium Citri Reticulatae is regulated the flow of vital energy in tune, drying dampness to eliminate phlegm；Exocarpium Citri Grandis regulating the flow of QI to ease the stomach, Drying dampness to eliminate phlegm is double to help digestion；In Radix Aucklandiae pain relieving, circulation of qi promoting, tune；Three medicines are adjuvant drug；Radix Glycyrrhizae invigorating middle warmer benefit Gas, the mitigation property of medicine are for making medicine.

The Chinese medicine composition for the treatment of cyclomastopathy of the present invention, according to theory of Chinese medical science preparation Becoming, compatibility is reasonable, and each taste Chinese medicine combines according to monarch, plays maximum drug effect, Chinese medicine system Agent, toxic and side effects is little, low cost.

Detailed description of the invention

Embodiment 1

A kind of Chinese medicine composition treating cyclomastopathy, is made up of according to weight fraction following components (every part of 1g):

Radix Bupleuri (vinegar-fried) 3 parts, Pericarpium Citri Reticulatae 3 parts, Fructus Citri Sarcodactylis 3 parts, Exocarpium Citri Grandis 3 parts, Rhizoma Curcumae 3 Part, the Radix Aucklandiae 3 parts, Radix Curcumae 6 parts, Cortex Moutan 6 parts, Herba Menthae 3 parts, Herba Leonuri 10 parts, red Chinese herbaceous peony 5 parts, Herba Taraxaci 10 parts, 3 parts of Radix Glycyrrhizae.

Concrete preparation process is as follows:

(1) weigh each component in compositions according to quantity, utilize warm water to wash the impurity on surface；

(2) composition powder is broken to 500 mesh；

(3) compositions after pulverizing joins in 1000 parts of water immersion 30min, post-cooked Boiling 20min；

(4) cooled and filtered, concentrates the filtrate to 300 parts, and filtering residue is dried.

Embodiment 2

A kind of Chinese medicine composition treating cyclomastopathy, is made up of according to weight fraction following components (every part of 1g):

Radix Bupleuri (vinegar-fried) 7 parts, Pericarpium Citri Reticulatae 7 parts, Fructus Citri Sarcodactylis 7 parts, Exocarpium Citri Grandis 7 parts, Rhizoma Curcumae 7 Part, the Radix Aucklandiae 7 parts, Radix Curcumae 9 parts, Cortex Moutan 9 parts, Herba Menthae 7 parts, Herba Leonuri 15 parts, red Chinese herbaceous peony 10 parts, Herba Taraxaci 20 parts, 7 parts of Radix Glycyrrhizae.

Concrete preparation process is as follows:

(1) weigh each component in compositions according to quantity, utilize warm water to wash the impurity on surface；

(2) composition powder is broken to 500 mesh；

(3) compositions after pulverizing joins in 1000 parts of water immersion 30min, post-cooked Boiling 20min；

(4) cooled and filtered, concentrates the filtrate to 300 parts, and filtering residue is dried.

Embodiment 3

A kind of Chinese medicine composition treating cyclomastopathy, is made up of according to weight fraction following components (every part of 1g):

Radix Bupleuri (vinegar-fried) 10 parts, Pericarpium Citri Reticulatae 10 parts, Fructus Citri Sarcodactylis 10 parts, Exocarpium Citri Grandis 10 parts, cowherb Art 10 parts, the Radix Aucklandiae 10 parts, Radix Curcumae 12 parts, Cortex Moutan 12 parts, Herba Menthae 10 parts, Herba Leonuri 20 parts, Radix Paeoniae Rubra 15 parts, Herba Taraxaci 30 parts, 10 parts of Radix Glycyrrhizae.

Concrete preparation process is as follows:

(1) weigh each component in compositions according to quantity, utilize warm water to wash the impurity on surface；

(2) composition powder is broken to 500 mesh；

(3) compositions after pulverizing joins in 1000 parts of water immersion 30min, post-cooked Boiling 20min；

(4) cooled and filtered, concentrates the filtrate to 300 parts, and filtering residue is dried.

Experimental example:

Selecting 45 example cyclomastopathy patients, wherein unilateral breast morbidity and the morbidity of bilateral breast are each 16 examples.After breast molybdenum target takes the photograph sheet inspection eliminating breast tumor, it is diagnosed as mammary gland capsule lobule Sick 14 examples of hypertrophy, Cystic hyperplasia breast 8 example, mastalgia 7 example.

Therapeutic Method: the decoction of the preparation of embodiment 2, every day 1 dose, every day 2 times, often Secondary 150g, filtering residue temperature after appropriate hot-water soak 30min spreads on ill breast, within 20 days, is 1 The course for the treatment of, continuously 5 courses for the treatment of of treatment.

Criterion of therapeutical effect

" the disease of tcm Standardization of diagnosis and curative effect " issued with reference to State Administration of Traditional Chinese Medicine is formulated.

1. recovery from illness: distending pain of the breast and lump disappear, takes the photograph sheet inspection in conjunction with breast molybdenum target and confirms mammary gland Hypertrophy sign disappears.Within after drug withdrawal 3 months, do not recur.

The most effective: distending pain of the breast disappears, and lump maximum gauge reduces more than 50%, mammary gland molybdenum Target is taken the photograph sheet inspection and is confirmed that cyclomastopathy tuberosity reduces or hypertrophy gland density alleviates and is consistent with clinic.

The most effective: distending pain of the breast alleviates, physical palpation mass reduction, but not as good as 50%, breast Gland mammography in nonpalpable breast inspection confirms that cyclomastopathy takes a turn for the better, and is substantially consistent with clinical symptoms and palpation.

The most invalid: distending pain of the breast is not improved compared with before treatment with lump, and mammary gland molybdenum Target is taken the photograph sheet inspection and is confirmed.

Through the observation of 5 courses for the treatment of, fully recover: 28 examples, effective: 12 examples, effectively: 4 examples, Invalid 1 example, total effective rate 97.8%, do not observe during whole treatment obvious bad instead Should.

Claims (3)

1. the Chinese medicine composition treating cyclomastopathy, it is characterised in that by following components according to Parts by weight form:

Vinegar-fried Radix Bupleuri 3-10 part, Pericarpium Citri Reticulatae 3-10 part, Fructus Citri Sarcodactylis 3-10 part, Exocarpium Citri Grandis 3-10 part, Rhizoma Curcumae 3-10 part, Radix Aucklandiae 3-10 part, Radix Curcumae 6-12 part, Cortex Moutan 6-12 part, Herba Menthae 3-10 Part, Herba Leonuri 10-20 part, Radix Paeoniae Rubra 5-15 part, Herba Taraxaci 10-30 part, Radix Glycyrrhizae 3-10 part.

The Chinese medicine composition for the treatment of cyclomastopathy the most according to claim 1, its feature exists In by following components by weight:

Vinegar-fried Radix Bupleuri 7 parts, Pericarpium Citri Reticulatae 7 parts, Fructus Citri Sarcodactylis 7 parts, Exocarpium Citri Grandis 7 parts, Rhizoma Curcumae 7 parts, The Radix Aucklandiae 7 parts, Radix Curcumae 9 parts, Cortex Moutan 9 parts, Herba Menthae 7 parts, Herba Leonuri 15 parts, Radix Paeoniae Rubra 10 Part, Herba Taraxaci 20 parts, 7 parts of Radix Glycyrrhizae.

3. prepare the Chinese medicine composition treating cyclomastopathy as claimed in claim 1 or 2 for one kind Method, it is characterised in that concrete preparation process is as follows:

(1) weigh each component in compositions according to quantity, utilize warm water to wash the impurity on surface；

(2) composition powder is broken to 500 mesh；

(3) compositions after pulverizing joins immersion 30min in 1000 parts of water, boils afterwards 20min；

(4) cooled and filtered, concentrates the filtrate to 300 parts, and filtering residue is dried.