CN103947743A - Drying method of hericium erinaceus - Google Patents
Drying method of hericium erinaceus Download PDFInfo
- Publication number
- CN103947743A CN103947743A CN201410204924.3A CN201410204924A CN103947743A CN 103947743 A CN103947743 A CN 103947743A CN 201410204924 A CN201410204924 A CN 201410204924A CN 103947743 A CN103947743 A CN 103947743A
- Authority
- CN
- China
- Prior art keywords
- hericium erinaceus
- dry
- days
- drying method
- drying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a drying method of hericium erinaceus. The drying method comprises the following steps: piling newly collected hericium erinaceus in dankness for 2-5 days; and drying. According to the prepared hericium erinaceus, the content of polysaccharide of main effective components is high and the pharmacological activity is high.
Description
Invention field
The present invention relates to medicine method for making, the particularly drying means of a kind of Hericium erinaceus, belongs to medical technical field.
Background technology
Hericium erinaceus (formal name used at school: Hericium erinaceus), cries again Hericium erinaceus, monkey mushroom, and hedgehog hydnum, monkey mushroom, is the traditional famous and precious medicinal fungi of China.The pharmacology of nearly more than ten years and clinical research find that it has antiulcer, anti-inflammatory, antitumor, anti-ageing, antifatigue, liver protecting, hypoglycemic, reducing blood lipid, hypotensive, immunity conditioning, the effect such as calm.The pharmacologically active that how to improve Hericium erinaceus is medical worker's vital task.
Summary of the invention
The object of this invention is to provide the dry new method of a kind of Hericium erinaceus, the Hericium erinaceus that the method is dry, main active ingredient polyoses content is high, and pharmacologically active is strong.
The present invention is achieved in that
A drying means for Hericium erinaceus, is characterized in that: get the Hericium erinaceus of newly gathering, the 2-5 days that banks up is dry.
The drying means of a kind of Hericium erinaceus of the present invention, is characterized in that: dry is that heap postpone is dried or dries or oven dry or freeze-drying.
So far completed the present invention, the Hericium erinaceus of preparing by drying means of the present invention, main active ingredient polyoses content is high, and pharmacologically active is strong.
Further illustrate usefulness of the present invention below by test example, test example is intended to further illustrate usefulness of the present invention, but not limitation of the present invention.
By with a collection of Hericium erinaceus of newly gathering, process by the following method.
1) dry: shady and cool ventilation place, spread out and dry;
2) dry: 50 DEG C of following oven dry;
3) oven dry of banking up: bank up 3 days at dark and damp place, 50 DEG C of following oven dry.
One, the dry hericium erinaceum polysaccharide content comparison of distinct methods
The preparation of reference substance solution: get glucose reference substance appropriate, accurately weighed, add water and make the solution of every 1ml containing 0.1mg, to obtain final product.
The preparation of calibration curve: precision measures reference substance solution 0.2ml respectively, 0.4m1, 0.6ml, 0.8ml, 1.0ml, 1.2ml, put in 10ml tool plug test tube, add water to 2.0ml, precision adds sulfuric acid anthrone solution, and (precision takes anthrone 0.1g, adding 80% sulfuric acid solution 100ml makes to dissolve, shake up) 6ml, shake up, put in water-bath and heat 15 minutes, take out, put in people's ice bath cooling 15 minutes, taking corresponding reagent as blank, according to " Chinese pharmacopoeia " UV-VIS spectrophotometry, measure absorbance at 625nm wavelength place, taking absorbance as ordinate, concentration is abscissa, drawing standard curve.
The preparation of need testing solution: get the about 2g of each sample powder, accurately weighed, put in apparatus,Soxhlet's, 90ml adds water, electric heater heating and refluxing extraction is to extracting liquid colourless, and extract is transferred in 100ml measuring bottle, adds water to scale, shaking up. precision measures 10ml, adds ethanol 150ml, shakes up, place 12 hours for 4 DEG C, take out, centrifugal, the supernatant that inclines, precipitation is dissolved in water, and is transferred in 50ml measuring bottle, add water to scale, shake up, to obtain final product.
Determination method: precision measures need testing solution 2ml, put in 10ml tool plug test tube, method under the preparation of sighting target directrix curve, from " precision adds sulfuric acid anthrone solution 6ml ", measure absorbance in accordance with the law, read the weight (mg) containing glucose in need testing solution from calibration curve, calculate, to obtain final product.
Press dry product and calculate, in DEXTROSE ANHYDROUS (C6H12O6), the results are shown in Table 1 containing hericium erinaceum polysaccharide.
Table 1 distinct methods is dried hericium erinaceum polysaccharide content (%)
| Drying means | Dry | Dry | The oven dry of banking up |
| Content (%) | 4.38 | 4.37 | 6.25 |
Found out by table 1, Hericium erinaceus " heap postpone is dry ", polyoses content is apparently higher than " drying " and " oven dry ".
Two, the dry Hericium erinaceus of distinct methods causes the protective effect comparison of gastric mucosa damage to ethanol.
Choose healthy SD rat, male and female half and half, weight 180-220g, is divided into that control group, Hericium erinaceus dry group, dry group, oven dry group, the freezing oven dry group of banking up at random, totally 5 groups, 10 every group, every day gastric infusion 1 time, 1 2mg/kg, continuous 7 days, control group gave equivalent distilled water.Before experiment, first fasting 48 h of rat, freely drink water, after last administration, every rat oral gavage absolute ethyl alcohol 1mL/ of 1h only, put to death animal after the de-cervical vertebra of 1h, close orifice of the stomach by clip, inject 1% formaldehyde 5mL from pylorus, folder closes pylorus again, put into the fixing 10min of 1% formalin, cut off coat of the stomach along greater curvature, measure damaged length, using damaged length (width is greater than 1 mm to be doubled) summation as gastric mucosal damage index, and calculate inhibiting rate.The results are shown in Table 2.
Inhibiting rate (%)=(control group UI one administration group UI) ÷ control group UI × 100%
The protective effect result of the dry Hericium erinaceus of table 2 distinct methods to mucosal lesion
| Group | Dosage (mg/kg) | Gastric mucosal damage index (mm) | Inhibiting rate (%) |
| Control group | ? | 97.6±34.2 | ? |
| Dry group | 2 | 58.3±26.7 | 40.26 |
| Oven dry group | 2 | 58.3±25.9 | 40.27 |
| The oven dry group of banking up | 2 | 49.7±24.6 | 49.08 |
Result shows, the dry Hericium erinaceus of distinct methods causes gastric mucosa damage to ethanol all protective effect, and wherein, banking up, it is best to dry protective effect.
Detailed description of the invention
A drying means for Hericium erinaceus, is characterized in that: get the Hericium erinaceus of newly gathering, the 2-5 days that banks up, dries or dry or oven dry or freeze-drying.
embodiment 1
Get the Hericium erinaceus of newly gathering, bank up 2 days at dark and damp place, dry.
embodiment 2
Get the Hericium erinaceus of newly gathering, bank up in the cool 3 days, dry.
embodiment 3
Get the Hericium erinaceus of newly gathering, bank up 4 days indoor, dry.
embodiment 4
Get the Hericium erinaceus of newly gathering, bank up 5 days at dark and damp place, put in freeze dryer, solidification point is controlled at-30 DEG C; Reach and control after temperature, open immediately vavuum pump and be evacuated to below drying chamber pressure 50Pa, then start heater switch, promote distillation, the temperature of distillation should be controlled at below 40 DEG C; The temperature of resolution phase should be controlled at below 45 DEG C, to dry.
embodiment 5
Get the Hericium erinaceus of newly gathering, bank up 3 days outdoor, dry.
embodiment 6
Get the Hericium erinaceus of newly gathering, bank up 5 days at dark and damp place, dry.
Claims (2)
1. a drying means for Hericium erinaceus, is characterized in that: get the Hericium erinaceus of newly gathering, the 2-5 days that banks up at dark and damp place is dry.
2. according to the drying means of a kind of Hericium erinaceus of claim 1, it is characterized in that: dry is that heap postpone is dried or dries or oven dry or freeze-drying.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410204924.3A CN103947743A (en) | 2014-05-15 | 2014-05-15 | Drying method of hericium erinaceus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410204924.3A CN103947743A (en) | 2014-05-15 | 2014-05-15 | Drying method of hericium erinaceus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103947743A true CN103947743A (en) | 2014-07-30 |
Family
ID=51325214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410204924.3A Pending CN103947743A (en) | 2014-05-15 | 2014-05-15 | Drying method of hericium erinaceus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103947743A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104154716A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Application of freeze-drying technology in high-activity Gymnadenia conopsea preparation |
| CN104180622A (en) * | 2014-08-25 | 2014-12-03 | 济南康众医药科技开发有限公司 | Drying method for roots of red-rooted salvia |
| CN110326700A (en) * | 2019-08-05 | 2019-10-15 | 上海雷允上药业有限公司 | A kind of Hericium erinaceus pressed candy and preparation method thereof and purposes |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406220A (en) * | 2011-11-27 | 2012-04-11 | 河南科技大学 | Quick drying method of hericium erinaceus |
| CN102920778A (en) * | 2012-11-27 | 2013-02-13 | 福建宝草堂生物科技有限公司 | Mesona chinensis harvesting and primary processing method |
| CN102986449A (en) * | 2012-08-21 | 2013-03-27 | 南阳市乾景中药材开发有限公司 | Method for improving mushroom quality |
| CN103408368A (en) * | 2013-08-03 | 2013-11-27 | 邬金飞 | Compatibility and manufacturing method of Hericium erinaceus cultivation material |
-
2014
- 2014-05-15 CN CN201410204924.3A patent/CN103947743A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406220A (en) * | 2011-11-27 | 2012-04-11 | 河南科技大学 | Quick drying method of hericium erinaceus |
| CN102986449A (en) * | 2012-08-21 | 2013-03-27 | 南阳市乾景中药材开发有限公司 | Method for improving mushroom quality |
| CN102920778A (en) * | 2012-11-27 | 2013-02-13 | 福建宝草堂生物科技有限公司 | Mesona chinensis harvesting and primary processing method |
| CN103408368A (en) * | 2013-08-03 | 2013-11-27 | 邬金飞 | Compatibility and manufacturing method of Hericium erinaceus cultivation material |
Non-Patent Citations (3)
| Title |
|---|
| 刘晓龙等: "《食用菌生产流程图谱•猴头菇》", 31 March 2010, article "采后的管理", pages: 87 - 1 * |
| 聂光军等: "堆热法提取浮萍多糖", 《安徽工程科技学院学报》, vol. 25, no. 4, 31 December 2010 (2010-12-31), pages 6 - 1 * |
| 钟少敏: "猴头菇的干制技术", 《食用菌》, no. 1, 15 February 1995 (1995-02-15), pages 40 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104154716A (en) * | 2014-08-25 | 2014-11-19 | 济南康众医药科技开发有限公司 | Application of freeze-drying technology in high-activity Gymnadenia conopsea preparation |
| CN104180622A (en) * | 2014-08-25 | 2014-12-03 | 济南康众医药科技开发有限公司 | Drying method for roots of red-rooted salvia |
| CN110326700A (en) * | 2019-08-05 | 2019-10-15 | 上海雷允上药业有限公司 | A kind of Hericium erinaceus pressed candy and preparation method thereof and purposes |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103948638A (en) | Drying method of medical fungi | |
| CN103977034A (en) | Drying method of medicinal fungi | |
| TWI671081B (en) | The use of composition containing a plant extracts for enhancing the gene expression of transglutaminase 1, keratin, aquaporin 3, filaggrin, , glucocerebrosidase, hyaluronan synthase | |
| Guo et al. | Evaluation of antiviral effect and toxicity of total flavonoids extracted from Robinia pseudoacacia cv. idaho | |
| CN104367595A (en) | Application of American cockroach dried by different methods in preparation of medicines | |
| CN103977041A (en) | Drying method of ganoderma applanatum pat | |
| CN103947743A (en) | Drying method of hericium erinaceus | |
| CN103954100B (en) | The application of Refrigeration Technique in Hericium erinaceus is dry | |
| CN101703588A (en) | Shuanghuanglian in situ gel preparation and preparation method thereof | |
| CN103977040A (en) | Lucid ganoderma drying method | |
| CN102614242B (en) | Dropping pill of isatis root and folium isatidis and preparing method thereof | |
| CN105560379B (en) | Application of cortex mori fatty oil component in preparation of medicine for treating acute lung injury | |
| CN103948650A (en) | Drying method of artist's conk | |
| Ye et al. | Quantitative determination of triterpenoid glycosides in Fatsia japonica Decne. & Planch. using high performance liquid chromatography | |
| CN103977033A (en) | Hericium erinaceus drying method | |
| CN103550323B (en) | A kind of purposes and preparation method with the waistcoat seed extract of anti-tumor activity | |
| CN103408528B (en) | Chroman compound, as well as preparation method and application thereof | |
| CN103055191B (en) | Preparation method and quality detection method of traditional Chinese medicine for treating hematuresis caused by nephritis | |
| CN103948648A (en) | Application of freezing technology in drying medicinal fungi | |
| CN109464488B (en) | Honeysuckle total flavone and preparation method and application thereof | |
| CN109470792B (en) | HPLC method for simultaneously determining eight active ingredients in codonopsis pilosula | |
| CN102614222A (en) | Sea cucumber extract rich in triterpene sapogenin and preparation method and application thereof | |
| CN105362362A (en) | Polygonum aviculare ethyl acetate extract and preparation method and application | |
| CN102100807B (en) | Chinese medicine composition for regulating qi, widening chest and relieving pain as well as detection method thereof | |
| CN104147087A (en) | Drying method of eucommia ulmoides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140730 |