CN103932273B - One main laminaria Lactobacillus buccal tablet and preparation method thereof - Google Patents
One main laminaria Lactobacillus buccal tablet and preparation method thereof Download PDFInfo
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- CN103932273B CN103932273B CN201410194609.7A CN201410194609A CN103932273B CN 103932273 B CN103932273 B CN 103932273B CN 201410194609 A CN201410194609 A CN 201410194609A CN 103932273 B CN103932273 B CN 103932273B
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- thallus
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- thallus laminariae
- thallus eckloniae
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- 241000186660 Lactobacillus Species 0.000 title claims abstract description 26
- 229940039696 lactobacillus Drugs 0.000 title claims abstract description 26
- 229940046011 buccal tablet Drugs 0.000 title claims abstract description 16
- 239000006189 buccal tablet Substances 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 241001466453 Laminaria Species 0.000 title claims abstract description 8
- 238000000855 fermentation Methods 0.000 claims abstract description 30
- 230000004151 fermentation Effects 0.000 claims abstract description 30
- 239000000843 powder Substances 0.000 claims abstract description 30
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 26
- 241000894006 Bacteria Species 0.000 claims abstract description 20
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000004310 lactic acid Substances 0.000 claims abstract description 13
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 13
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims abstract description 12
- 229930006000 Sucrose Natural products 0.000 claims abstract description 9
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229920000858 Cyclodextrin Polymers 0.000 claims abstract description 6
- 239000001116 FEMA 4028 Substances 0.000 claims abstract description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 6
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 6
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 6
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 6
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims abstract description 6
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims abstract description 6
- 229960004853 betadex Drugs 0.000 claims abstract description 6
- 239000000796 flavoring agent Substances 0.000 claims abstract description 6
- 235000019634 flavors Nutrition 0.000 claims abstract description 6
- 239000008103 glucose Substances 0.000 claims abstract description 6
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 6
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229960004793 sucrose Drugs 0.000 claims abstract description 6
- 239000000811 xylitol Substances 0.000 claims abstract description 6
- 235000010447 xylitol Nutrition 0.000 claims abstract description 6
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 6
- 229960002675 xylitol Drugs 0.000 claims abstract description 6
- 239000008187 granular material Substances 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims abstract description 5
- 239000000945 filler Substances 0.000 claims abstract description 4
- 238000005469 granulation Methods 0.000 claims abstract description 4
- 230000003179 granulation Effects 0.000 claims abstract description 4
- 239000000314 lubricant Substances 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 239000000080 wetting agent Substances 0.000 claims abstract description 4
- 241000512259 Ascophyllum nodosum Species 0.000 claims description 20
- 240000001929 Lactobacillus brevis Species 0.000 claims description 14
- 235000013957 Lactobacillus brevis Nutrition 0.000 claims description 14
- 240000006024 Lactobacillus plantarum Species 0.000 claims description 14
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims description 14
- 241000192130 Leuconostoc mesenteroides Species 0.000 claims description 14
- 229940072205 lactobacillus plantarum Drugs 0.000 claims description 14
- 238000004108 freeze drying Methods 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 7
- 230000003321 amplification Effects 0.000 claims description 6
- 239000012531 culture fluid Substances 0.000 claims description 6
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 6
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 6
- 239000007779 soft material Substances 0.000 claims description 6
- 239000003826 tablet Substances 0.000 claims description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 5
- 239000002002 slurry Substances 0.000 claims description 5
- 238000009835 boiling Methods 0.000 claims description 4
- 238000011081 inoculation Methods 0.000 claims description 4
- 239000003223 protective agent Substances 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims description 4
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 3
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 3
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000007710 freezing Methods 0.000 claims description 3
- 230000008014 freezing Effects 0.000 claims description 3
- 235000019359 magnesium stearate Nutrition 0.000 claims description 3
- 239000004531 microgranule Substances 0.000 claims description 3
- 239000011812 mixed powder Substances 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 238000001291 vacuum drying Methods 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 2
- 230000004913 activation Effects 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 210000000481 breast Anatomy 0.000 abstract description 3
- 235000013305 food Nutrition 0.000 abstract description 3
- 230000000529 probiotic effect Effects 0.000 abstract description 3
- 235000008935 nutritious Nutrition 0.000 abstract description 2
- 239000006041 probiotic Substances 0.000 abstract description 2
- 235000018291 probiotics Nutrition 0.000 abstract description 2
- 238000005516 engineering process Methods 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 235000019629 palatability Nutrition 0.000 description 3
- 230000000975 bioactive effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- MXNRLFUSFKVQSK-UHFFFAOYSA-N 2-Amino-6-(trimethylazaniumyl)hexanoate Chemical compound C[N+](C)(C)CCCCC(N)C([O-])=O MXNRLFUSFKVQSK-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000010855 food raising agent Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- -1 polysaccharide sulfate Chemical class 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/60—Edible seaweed
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/121—Brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/161—Mesenteroides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Edible Seaweed (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to main laminaria breast Lactobacillus buccal tablet and preparation method thereof, belong to food processing field. The primary raw material of described Thallus Laminariae (Thallus Eckloniae) Lactobacillus buccal tablet is by weight percentage: Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder 40��60%, beta-cyclodextrin 1��4%, maltodextrin 10��20%, xylitol 5-10%, glucose powder 10��20%, cane sugar powder 5��20%, citric acid 0.5��2%, Oleum menthae 0.1-0.4%. The present invention by Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder with filler, local flavor regulator, mix lubricant uniformly, with suitable quantity of water for wetting agent, prepares Thallus Laminariae (Thallus Eckloniae) lactic acid bacteria buccal tablet by operations such as granulation, dry, granulate, tablettings. Product of the present invention contains substantial amounts of active probiotic and functional components, has nutritious, unique flavor, the advantage carrying instant.
Description
Technical field
The present invention relates to main laminaria breast Lactobacillus buccal tablet and preparation method thereof, belong to food processing field.
Background technology
Thallus Laminariae (Thallus Eckloniae) heat content is low, protein content is medium, mineral is abundant, has several functions active component, and research shows that Thallus Laminariae (Thallus Eckloniae) has the several functions such as blood fat reducing, blood sugar lowering, preventing and treating goiter, beauty treatment, fat-reducing slow down aging. At present, laminaria culture yield is huge, but processing method is simple and easy, and converted products is based on limnetic dry kelp, kelp knot, sea-tangle roll, and the converted products form that Thallus Laminariae (Thallus Eckloniae) is relevant is single, and kind is abundant not, lacks innovation. Traditional kelp processing product is difficult to meet the food service industry of development, and has seriously blocked making full use of Thallus Laminariae (Thallus Eckloniae) resource.
Lactic acid bacteria, as a kind of probiotic bacteria, has and improves human gastrointestinal tract function, recovers colony balance in human body intestinal canal, forms antibacterial biological barrier, safeguards the effect of health. Buccal tablet has and carries instant, good palatability, oral cavity time of staying length, adaptation population's feature widely. This fermented type kelp processing product of Thallus Laminariae (Thallus Eckloniae) Lactobacillus buccal tablet, in conjunction with probiotic action, meets people instantly and pursues health, life style easily.
Summary of the invention
It is an object of the invention to provide main laminaria breast Lactobacillus buccal tablet and preparation method thereof.
The technology implementation scheme of the present invention is as follows:
One main laminaria Lactobacillus buccal tablet, its primary raw material is by weight percentage: Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder 40��60%, beta-cyclodextrin 1��4%, maltodextrin 10��20%, xylitol 5-10%, glucose powder 10��20%, cane sugar powder 5��20%, citric acid 0.5��2%, Oleum menthae 0.1-0.4%, above each percentage ratio sum is 100%;
The preparation process of described Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder is as follows:
1) prepared by kelp paste: the plant pulverizer coarse crushing of dry Thallus Laminariae (Thallus Eckloniae), after being crushed to the particle mean size microgranule less than 100 microns with super micron mill again, addition accounts for the dry water of Thallus Laminariae (Thallus Eckloniae) weight 100%-500% and the white sugar of 2-8% is sized mixing, through boiling sterilization 3 minutes, cooling rapidly, prepares kelp paste;
2) prepared by lactobacillus leaven: Lactobacillus plantarum (Lactobacillusplantarum), Leuconostoc mesenteroides (Leuconostocmesenteroides) and Lactobacillus brevis (Lactobacillusbrevis) strain aseptically carry out activation and conventional amplification culture respectively, Lactobacillus plantarum in culture fluid after amplification culture, Leuconostoc mesenteroides bacterium number content be 6.0 �� 109~7.0��109CFU/mL, the bacterium number content of Lactobacillus brevis is 1.5 �� 109~3.5��109CFU/mL, respectively by mixing by the weight ratio of 1��2:2��3:2��3 containing bacteria culture fluid after Lactobacillus plantarum (Lactobacillusplantarum), Leuconostoc mesenteroides (Leuconostocmesenteroides) and Lactobacillus brevis (Lactobacillusbrevis) strain expanded culture, prepare lactobacillus leaven;
3) kelp paste lactic acid bacteria fermentation: the kelp paste of preparation is imported in fermentation tank, inoculation accounts for the lactobacillus leaven that kelp paste percentage by weight is 2-5%, after sealing, the fermentation temperature regulated in tank is 25-30 DEG C, ferment 5-7 days, the total acid content of fermentation liquid is in lactic acid >=1.5g/100g, it is thus achieved that rich in the Thallus Laminariae (Thallus Eckloniae) fermentation slurry of Lactobacillus;
4) Thallus Laminariae (Thallus Eckloniae) yeast powder is prepared in lyophilization: adding percentage by weight in above-mentioned Thallus Laminariae (Thallus Eckloniae) fermentation slurry is that the trehalose of 3-6% is as lactic acid bacteria freeze drying protective agent; after freezing; vacuum lyophilization 18��24h at-20��-40 DEG C, after pulverizing, obtains Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder.
The preparation method of described Thallus Laminariae (Thallus Eckloniae) Lactobacillus buccal tablet, comprises the following steps:
(1) allotment: Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder is mixed homogeneously by following percentage by weight with filler, local flavor regulator, wherein Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder 40��60%, beta-cyclodextrin 1��4%, maltodextrin 10��20%, xylitol 5-10%, glucose powder 10��20%, cane sugar powder 5��20%, citric acid 0.5��2%, Oleum menthae 0.1-0.4%, above each percentage ratio sum is 100%;
(2) granulate: in above-mentioned deployed mixed powder, add appropriate amounts of sterilized water as wetting agent, make moistening uniform, prepare soft material, the soft material made is agglomerating with holding, after firmly pressing through 16 eye mesh screens granulations, put into 10 DEG C ~ 20 DEG C cold drying in vacuum drying oven and prepare Thallus Laminariae (Thallus Eckloniae) ferment particulate;
(3) tabletting: dried Thallus Laminariae (Thallus Eckloniae) ferment particulate, add account for Thallus Laminariae (Thallus Eckloniae) ferment particulate percentage by weight be the magnesium stearate of 1��5% as lubricant, and add proper amount of edible essence, mix homogeneously, stand 10 ~ 40 minutes, be pressed into, with tablet machine, the tablet that specification is 0.5��2g.
The technology of the present invention feature:
The present invention is with dry Thallus Laminariae (Thallus Eckloniae) for raw material, after micronizing, add water and size mixing, after boiling sterilization, inoculation mixed lactic bacterium leavening agent ferments, it is possible to the dissolution being greatly facilitated in Thallus Laminariae (Thallus Eckloniae) the bioactive substance such as the nutritional labeling such as protein and aminoacid, vitamin, mineral and Thallus Laminariae (Thallus Eckloniae) polysaccharide sulfate, mannitol, laminine; Vacuum freeze-drying method is adopted to be dried to ensure the lactic bacteria activity of final products in conjunction with lactic acid bacteria freeze drying protective agent; The Thallus Laminariae (Thallus Eckloniae) lactic acid bacteria buccal tablet of preparation has good dispersibility and palatability in the oral cavity, does not easily stay slag, sour and sweet palatability containing changing in the oral cavity, has the peculiar flavour of Thallus Laminariae (Thallus Eckloniae). Buccal tablet is nutritious, containing the multiple bioactive functions composition in substantial amounts of Lactobacillus and Thallus Laminariae (Thallus Eckloniae).
Detailed description of the invention
It is below specific embodiment of the invention case, is used for describing the present invention, but the present invention is not limited only to this.
Embodiment 1
1, prepared by kelp paste: the plant pulverizer coarse crushing of dry Thallus Laminariae (Thallus Eckloniae), after being crushed to, with super micron mill, the microgranule that particle mean size is 45 microns again, add and account for the dry water of Thallus Laminariae (Thallus Eckloniae) weight 400% and after the white sugar etc. of 5% sizes mixing, through boiling sterilization 3 minutes, cooling rapidly, prepares kelp paste.
2, prepared by lactobacillus leaven: choose Lactobacillus plantarum, Leuconostoc mesenteroides, Lactobacillus brevis strain (Lactobacillus plantarum (Lactobacillusplantarum), Leuconostoc mesenteroides (Leuconostocmesenteroides), Lactobacillus brevis (Lactobacillusbrevis) is purchased from Chinese industrial Microbiological Culture Collection administrative center) carry out respectively activating and amplification culture. Lactobacillus plantarum in culture fluid after amplification culture, Leuconostoc mesenteroides bacterium number content be 6.0 �� 109CFU/mL, the bacterium number content of Lactobacillus brevis is 2.0 �� 109CFU/mL, respectively by mixing by the weight ratio of 1:2:2 containing bacteria culture fluid after above-mentioned strain expanded culture, prepares lactobacillus leaven.
3, kelp paste lactic acid bacteria fermentation: kelp paste lactic acid bacteria fermentation: the kelp paste of preparation is imported in fermentation tank, inoculation accounts for the lactobacillus leaven that kelp paste percentage by weight is 3%, after sealing, the fermentation temperature regulated in tank is 25-30 DEG C, ferment 5 days, it is thus achieved that rich in the Thallus Laminariae (Thallus Eckloniae) fermentation slurry of Lactobacillus.
4, Thallus Laminariae (Thallus Eckloniae) yeast powder is prepared in lyophilization: add trehalose that percentage by weight is 4% in being starched by above-mentioned Thallus Laminariae (Thallus Eckloniae) leaven as lactic acid bacteria freeze drying protective agent; after freezing; vacuum lyophilization 24h at-30 DEG C, after pulverizing, obtains the Thallus Laminariae (Thallus Eckloniae) yeast powder rich in Lactobacillus.
5, allotment: Thallus Laminariae (Thallus Eckloniae) yeast powder is mixed homogeneously by following percentage by weight with filler, local flavor regulator, wherein Thallus Laminariae (Thallus Eckloniae) fermentation superfine powder 55%, beta-cyclodextrin 2%, xylitol 8%, maltodextrin 15%, glucose powder 15%, cane sugar powder 3.8%, citric acid 1%, Oleum menthae 0.2%.
6, granulate: in above-mentioned deployed mixed powder, add suitable quantity of water as wetting agent, make moistening uniform, prepare soft material. The soft material made is agglomerating with holding, after firmly pressing through 16 eye mesh screens granulations, put in vacuum drying oven in 15 DEG C of dry prepared Thallus Laminariae (Thallus Eckloniae) ferment particulate.
7, tabletting: dried granule, adds and accounts for magnesium stearate that weight percentage is 1.2% as lubricant, and add proper amount of edible essence, and mix homogeneously stands 20 minutes, is pressed into, with tablet machine, the tablet that specification is 1g.
Claims (2)
1. a main laminaria Lactobacillus buccal tablet, it is characterized in that: the primary raw material of described Thallus Laminariae (Thallus Eckloniae) Lactobacillus buccal tablet is by weight percentage: Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder 40��60%, beta-cyclodextrin 1��4%, maltodextrin 10��20%, xylitol 5-10%, glucose powder 10��20%, cane sugar powder 5��20%, citric acid 0.5��2%, Oleum menthae 0.1-0.4%, above each percentage ratio sum is 100%;
The preparation process of described Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder is as follows:
1) prepared by kelp paste: the plant pulverizer coarse crushing of dry Thallus Laminariae (Thallus Eckloniae), after being crushed to the particle mean size microgranule less than 100 microns with super micron mill again, addition accounts for the dry water of Thallus Laminariae (Thallus Eckloniae) weight 100%-500% and the white sugar of 2-8% is sized mixing, through boiling sterilization 3 minutes, cooling rapidly, prepares kelp paste;
2) prepared by lactobacillus leaven: Lactobacillus plantarum (Lactobacillusplantarum), Leuconostoc mesenteroides (Leuconostocmesenteroides) and Lactobacillus brevis (Lactobacillusbrevis) strain aseptically carry out activation and conventional amplification culture respectively, Lactobacillus plantarum in culture fluid after amplification culture, Leuconostoc mesenteroides bacterium number content be 6.0 �� 109��7.0 �� 109CFU/mL, the bacterium number content of Lactobacillus brevis is 1.5 �� 109��3.5 �� 109CFU/mL, respectively by mixing by the weight ratio of 1��2:2��3:2��3 containing bacteria culture fluid after Lactobacillus plantarum (Lactobacillusplantarum), Leuconostoc mesenteroides (Leuconostocmesenteroides) and Lactobacillus brevis (Lactobacillusbrevis) strain expanded culture, prepare lactobacillus leaven;
3) kelp paste lactic acid bacteria fermentation: the kelp paste of preparation is imported in fermentation tank, inoculation accounts for the lactobacillus leaven that kelp paste percentage by weight is 2-5%, after sealing, the fermentation temperature regulated in tank is 25-30 DEG C, ferment 5-7 days, the total acid content of fermentation liquid is in lactic acid >=1.5g/100g, it is thus achieved that rich in the Thallus Laminariae (Thallus Eckloniae) fermentation slurry of Lactobacillus;
4) Thallus Laminariae (Thallus Eckloniae) yeast powder is prepared in lyophilization: adding percentage by weight in above-mentioned Thallus Laminariae (Thallus Eckloniae) fermentation slurry is that the trehalose of 3-6% is as lactic acid bacteria freeze drying protective agent; after freezing; vacuum lyophilization 18��24h at-20��-40 DEG C, after pulverizing, obtains Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder.
2. the preparation method of Thallus Laminariae (Thallus Eckloniae) Lactobacillus buccal tablet as claimed in claim 1, it is characterised in that: described preparation method comprises the following steps:
(1) allotment: Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder is mixed homogeneously by following percentage by weight with filler, local flavor regulator, wherein Thallus Laminariae (Thallus Eckloniae) lactate fermentation superfine powder 40��60%, beta-cyclodextrin 1��4%, maltodextrin 10��20%, xylitol 5-10%, glucose powder 10��20%, cane sugar powder 5��20%, citric acid 0.5��2%, Oleum menthae 0.1-0.4%, above each percentage ratio sum is 100%;
(2) granulate: in above-mentioned deployed mixed powder, add appropriate amounts of sterilized water as wetting agent, make moistening uniform, prepare soft material, the soft material made is agglomerating with holding, after firmly pressing through 16 eye mesh screens granulations, put into 10 DEG C��20 DEG C cold drying in vacuum drying oven and prepare Thallus Laminariae (Thallus Eckloniae) ferment particulate;
(3) tabletting: dried Thallus Laminariae (Thallus Eckloniae) ferment particulate, add account for Thallus Laminariae (Thallus Eckloniae) ferment particulate percentage by weight be the magnesium stearate of 1��5% as lubricant, and add proper amount of edible essence, mix homogeneously, stand 10��40 minutes, be pressed into, with tablet machine, the tablet that specification is 0.5��2g.
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| CN105559064A (en) * | 2015-12-23 | 2016-05-11 | 于蜀豪 | Five-alga probiotic enzyme tablets and preparation method thereof |
| CN106937669A (en) * | 2017-03-13 | 2017-07-11 | 福州亿达食品有限公司 | A kind of crisp production method of high fine sea-tangle coarse cereals |
| CN108030097B (en) * | 2017-12-28 | 2021-03-30 | 福建拓天生物科技有限公司 | Probiotic freeze-dried powder for stimulating appetite of children |
| CN109288042A (en) * | 2018-09-20 | 2019-02-01 | 齐鲁工业大学 | A kind of method and application using probiotics fermention kelp preparation malignant tumour medical food raw material |
| CN114451532A (en) * | 2022-02-21 | 2022-05-10 | 福建农林大学 | Fermented kelp capable of regulating intestinal flora and preparation method thereof |
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