CN103919928A - Traditional Chinese medicinal preparation for treating hypertension - Google Patents

Traditional Chinese medicinal preparation for treating hypertension Download PDF

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CN103919928A
CN103919928A CN201410127482.7A CN201410127482A CN103919928A CN 103919928 A CN103919928 A CN 103919928A CN 201410127482 A CN201410127482 A CN 201410127482A CN 103919928 A CN103919928 A CN 103919928A
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traditional chinese
chinese medicinal
medicinal preparation
treating hypertension
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张世敏
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Abstract

The invention provides a traditional Chinese medicinal preparation for treating hypertension. The preparation is prepared from the following main raw materials in parts by weight: 15 parts of salvia miltiorrhiza, 12 parts of selfheal, 10 parts of harlequin glorybower leaf, 60 parts of astragalus membranaceus, 12 parts of scutellaria baicalensis, 12 parts of eucommia ulmoides, 12 parts of safflower, 10 parts of peach kernel, 10 parts of ricepaper pith, 12 parts of liquidambar formosana hance, 12 parts of chrysanthemum, 20 parts of poria, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of plantain seed, 30 parts of hawthorn, 12 parts of cassia seed, 30 parts of sticktight, 20 parts of liquorice and 30 parts of gynostemma pentaphylla. The traditional Chinese medicinal preparation for treating hypertension has an excellent effect for preventing and treating cerebral apoplexy, myocardial infarction, heart failure and chronic kidney diseases.

Description

The hypertensive Chinese medicine preparation for the treatment of three-hypers type
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to one and treat the hypertensive Chinese medicine preparation of three-hypers type.
Background technology
In prior art, three-hypers type hypertension is modal chronic disease, is also the topmost risk factor of cardiovascular and cerebrovascular disease, and apoplexy, myocardial infarction, heart failure and chronic kidney disease are its major complications.Hypertension is modal chronic disease, is also the topmost risk factor of cardiovascular and cerebrovascular disease, and apoplexy, myocardial infarction, heart failure and chronic kidney disease are its major complications.Both domestic and external facts have proved, hypertension is the disease that can prevent and control, reduces hyperpietic's blood pressure level, can obviously reduce apoplexy and the events of heart attack, significantly improves patient's life quality, effectively reduces disease burden.; Women before climacteric prevalence a little less than male, but after climacteric rapidly raise, even higher than male; High latitude cold district prevalence is higher than the warm area of low latitudes, and high altitude localities is higher than low altitude area; Relevant with dietary habit, salt and saturated fat are taken in higher, and mean blood pressure level and prevalence are also higher.Population of China hypertension is popular two relatively outstanding features: from south to the north, Prevalence of Hypertension is and increases progressively trend; Between different nationalities, Prevalence of Hypertension also has some differences, the national prevalence of living in the north or highlands is higher, the national prevalence of living in south or non-highlands is lower, this species diversity may be relevant with geographical environment, life style etc., and not yet finding has obvious genetic background difference between various nationalities.Treating hypertensive main purpose is to reduce to greatest extent cardiovascular morbidity and dead total danger, therefore require doctor in the hypertensive while for the treatment of, intervene the clinical disease that all reversibility cardiovascular risk factors of patient, target organ damage and merging exist.Be below 140/90mmHg for general hyperpietic's blood pressure lowering target, for the high risk patient such as complication with diabetes or nephropathy, blood pressure should be taken the circumstances into consideration to be down to more low-level in the tolerant situation of patient.Treating hypertensive main purpose is farthest to reduce cardiovascular and cerebrovascular complication to occur and dead overall danger [5], therefore, should, in the hypertensive while for the treatment of, intervene all other reversibility cardiovascular risk factors (as smoking, hypercholesterolemia or diabetes etc.), and suitably process simultaneous various clinical setting.Risk factor is more, and its degree is more serious, if also have clinical setting concurrently, cardiovascular diseases's absolute danger is just higher, also should be larger to the Intervention density of these risk factors.Relation between cardiovascular danger and blood pressure is in very large range seriality, even if also there is no obvious minimum dangerous threshold value within the scope of the so-called normal arterial pressure lower than 140/90mmHg.Therefore, blood pressure lowering should be realized as far as possible up to standard.
Summary of the invention
The object of the present invention is to provide one to there is the hypertensive Chinese medicine preparation for the treatment of three-hypers type, apoplexy, myocardial infarction, heart failure and chronic kidney disease disease are had to good preventive and therapeutic action.
The technical solution used in the present invention is: the hypertensive Chinese medicine preparation of described treatment three-hypers type, its primary raw material and weight portion respectively, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Spica Prunellaes, 10 parts of Folium et Ramulus Clerodendri Trichotomis, 60 parts of the Radixs Astragali, 12 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 12 parts, Flos Carthami, 10 parts, Semen Persicae, 10 parts of Medulla Tetrapanaciss, 12 parts of Fructus Liquidambaris, 12 parts of Flos Chrysanthemis, 20 parts, Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Semen Plantaginiss, 30 parts of Fructus Crataegis, 12 parts of Semen Cassiaes, 30 parts of Herba Bidentis Bipinnatae, 20 parts, Radix Glycyrrhizae, 30 parts of Herb Gynostemmae Pentaphylli.
In described Chinese medicine preparation and Chinese herb, its effect and pharmacological action respectively: Radix Salviae Miltiorrhizae: [nature and flavor] hardship, is slightly cold; [return through] enters the heart, Liver Channel.Function: promoting blood circulation to restore menstrual flow, evacuation of pus granulation promoting [curing mainly]: for menoxenia, blood stasis have a pain, amenorrhea, lump in the abdomen, coronary heart diseases and angina pectoris, ectopic pregnancy, vexed interior-heat, carbuncle sore tumefacting virus etc.
Spica Prunellae: [nature and flavor] bitter, acrid, cold.Enter liver, gallbladder meridian [function cures mainly] liver heat removing, eliminating stagnation, diuresis; Control the diseases such as pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension; Leaf can be for tea.Control that lymphoid tuberculosis, thyromegaly, scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia are shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia
Folium et Ramulus Clerodendri Trichotomi: [nature and flavor]: pungent, bitter, sweet, cool.[return through]: enter Liver Channel, gallbladder meridian, spleen channel.[function]: wind-damp dispelling.[curing mainly]: dispelling the wind and dampness pathogens arthralgia pain, hemiplegia, hypertension, migraine; Malaria, dysentery, hemorrhoid, carbuncle skin ulcer scabies.
The Radix Astragali: having another name called Radix Astragali, is the general designation of plant and Chinese crude drug.[nature and flavor]: sweet, tepor.[return through]: return lung, spleen, liver, kidney channel.[effect] Radix Astragali has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Radix Scutellariae: Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.For labiate Radix Scutellariae (Scutellaria baicalensis Georgi), be used as medicine with root.Radix Scutellariae: [nature and flavor with return through] hardship, cold.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.[function with cure mainly] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
The Cortex Eucommiae: [meridian distribution of property and flavor] Cortex Eucommiae, Gan Weixin, temperature.[function cures mainly] Cortex Eucommiae is warm in nature, and sweet in the mouth has invigorating the liver and kidney, strong waist knee joint, bone and muscle strengthening, antiabortive effect.The Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system, the excited Pituitary Adrenal cortex system of Cortex Eucommiae energy, adrenal cortex reinforcing function.The Cortex Eucommiae-plant ecosystem modern study also finds, the Cortex Eucommiae has and Radix Codonopsis, immunological enhancement function that the Radix Astragali is the same.All these has confirmed that ancient Chinese has the discussion of " clothes are made light of one's life by commiting suicide resistance to old for a long time " about the Cortex Eucommiae.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, frequent fetal movement, hypertension.
Flos Carthami: [chemical composition] is containing carthamin, neocarthamin, Flos Carthami quinone glycoside, Flos Carthami polysaccharide, Palmic acid, cinnamic acid, lauric acid.[nature and flavor] are warm in nature, acrid in the mouth.[function cures mainly] promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Medulla Tetrapanacis: [effect classification]: diuresis heat clearing away, ventilation stimulating milk secretion.[nature and flavor]: sweet in the mouth; Light; Cold nature.[return through]: enter lung, stomach warp.[effect and effect]: clear snobbish water; Lactogenesis.The puckery pain of main stranguria; Dysuria; Edema; Jaundice; Damp-warm diseases; Oliguria with reddish urine; Puerperal, breast was few; Amenorrhea; Leukorrhagia.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, agalactia.
Fructus Liquidambaris: Chinese sweet gum deciduous tree, high 20-40m.Bark taupe, square shape peels off.Leaf alternate; The long 3-7cm of petiole; Stipule is linear, caducous; Blade heart, normal 3 split, and leaf when children and on sprouting branch mostly is palmate 5 and splits, long 6-12cm, wide 8-15cm, sliver ovum shape triangle or avette, tip shape of tail is point gradually, base portion heart, there is serration at edge, and crown has gland shape prominent.Flower unisexuality, hermaphroditism, without perianth; Male flower pistac, becomes amentum to line up total shape again, is born in Zhi Ding; Stamen majority, filigree is not isometric; Female flower is lined up the head inflorescence of spheroidal; Calyx tooth 5, bores shape; Ovary half is the next, Room 2, style 2, stigma bending.Head infructescence spheroidal, diameter 2.5-4.5cm, surperficial spinosity, capsule has persistent calyx and style, and two lobes split, shallow the splitting of every lobe 2.Seed majority is tiny, flat.The florescence 3-4 month, the fruit phase 9-10 month.
Flos Chrysanthemi: the heat that disappears of avoiding heat, improving eyesight clears away heart-fire.Wind and heat dispersing, clear swollen removing toxic substances.For summer furuncle skin eczema fester and be also usually used in preventing cold.There is the effect of heat-clearing and toxic substances removing, be applicable to carbuncle, erysipelas, the disease such as laryngopharynx swelling and pain, wind-fire acute conjunctivitis of attacking on burning hot.[curing mainly] controls anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, furuncle, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.With wild chrysanthemum a bud just ready to burst alabastrum make.Wild chrysanthemum originates in mountain area, the south of the River, and its shape is yellowish green as rice, therefore claim Herba Dendranthematis indici bud.Record according to " augmentation DACAO detailed outline ": " Chuzhou goes out Herba Dendranthematis indici, and natives adopt its core and do it, as large in half Semen phaseoli radiati, very fragrant and light, He Huangliang.To relieving internal heat, loosely treat, dispel the wind, relieve inflammation or internal heat, improving eyesight is first.
Poria: [nature and flavor]: sweet, light, flat.[return through]: GUIXIN warp, lung meridian, spleen channel, kidney channel.[function]: diuretic medicine; Diuretics with the action of eliminating dampness.[curing mainly]: dysuria; Edema distension; Phlegm retention cough with dyspnea; Vomiting; Insufficiency of the spleen lack of appetite; Have loose bowels; Palpitation and restlessness; Insomnia forgetfulness; Seminal emission nebulousurine.
The Rhizoma Atractylodis Macrocephalae: [nature and flavor] bitter in the mouth; Sweet; [return through] warm in nature returns spleen; Stomach is through [effect] invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, dampness diuretic; Reduce phlegm, hidroschesis; Antiabortive; Increase appetite.
Semen Plantaginis: [nature and flavor]: sweet; Light; Cold nature.[return through]: return lung meridian; Liver Channel; Kidney channel; Urinary bladder channel.[function]: clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.[curing mainly]: main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily.
Fructus Crataegi: [nature and flavor] tepor, sweet, sour.[effect] can prevention and cure of cardiovascular disease, has blood vessel dilating, increases coronary flow, improves heart vigor, stimulating central nervous system system, reduces blood pressure and cholesterol, vessel softening and diuresis and sedation; There is cardiotonic, helpful to senile heart disease; Energy appetite-stimulating indigestion-relieving, offsets meat stagnation effect better; There is effect of activating blood circulation to dissipate blood stasis, contribute to remove local congestion state, traumatic injury is had to auxiliary curative effect; There is to contraction in uterus, has the effect expediting the emergence of anemia of pregnant woman just before giving birth time, and can promote uterine involution in puerperal; The substance blocking-up such as contained flavonoid and vitamin C, carotene, reduce the generation of free radical, and the immunity of enhancing body, has anti-aging, anticancer effect; In Fructus Crataegi, having relievings asthma reduces phlegm, the composition of anti-bacteria, treatment abdominal pain diarrhea.The patient of gastric ulcer, duodenal ulcer, hyperchlorhydria, should not eat Fructus Crataegi etc. containing organic superacid fruit, in order to avoid damage gastric mucosa increases the weight of the state of an illness.
Semen Cassiae: Semen Cassiae is annual suffruticose draft; The brightly yellowish color of Semen Cassiae, pod is elongated, four prism type; Little Semen Cassiae plant is less, and pod is shorter.There is a merit of improving eyesight and name with it.Semen Cassiae [nature and flavor] bitter in the mouth, sweet, salty, cold nature, [return through] enters liver, kidney, large intestine channel, [effect] loosening bowel to relieve constipation, blood fat reducing improving eyesight, [curing mainly] treatment constipation and hyperlipidemia, hypertension.Liver heat removing and eyesight improving, diuretic relieving constipation, has laxative action, reducing blood pressure and blood fat.
Herba Bidentis Bipinnatae: [nature and flavor] bitter in the mouth; Cold nature.[return through] returns liver, lung, large intestine channel.[function with cure mainly] heat-clearing and toxic substances removing, hemostasis antidiarrheal, dissipating blood stasis for subsidence of swelling.For appendicitis, nephritis, cholecystitis, enteritis, bacillary dysentery, hepatitis, peritonitis, upper respiratory tract infection, tonsillitis, laryngitis, amenorrhea, scalds venom, traumatic injury, skin infection, the diseases such as infantile convulsion, infantile malnutrition.
Radix Glycyrrhizae: [nature and flavor] sweet in the mouth, property is flat, nontoxic.[return through]: enter spleen, stomach, lung meridian [function cures mainly] treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Raw pathogenic fire purging heat, the ripe use exterior cold of fall apart of use, goes pharyngalgia, removes pathogenic heat, delays healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening.[effect and effect]: QI invigorating invigorating middle warmer; Relieving spasm to stop pain; Nourishing the lung to arrest cough; Eliminating fire and detoxication; Coordinating the actions of various ingredients in a prescription.Main asthenia lack of appetite; Leanness yellowish complexion; Shortness of breath and palpitation; Stomachache loose stool; The anxious pain of extremity contraction; Hysteria; Cough and asthma; Laryngopharynx swelling and pain; Carbuncle skin ulcer swells and ache; Infantile carbuncle; And medicine, alimentary toxicosis.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herb Gynostemmae Pentaphylli: [nature and flavor]: bitter in the mouth; Micro-sweet; Cool in nature.[return through]: return lung; Spleen; Kidney channel.[effect]: replenishing QI to invigorate the spleen, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing.[effect classification]: qi-restoratives medicine; Apophlegmatisant; Antipyretic.[curing mainly]: body void is weak; Nephrasthenia emission; Leukopenia; Hyperlipemia; Viral hepatitis; Chronic gastroenteritis; Chronic tracheitis.
Specific implementation method
The hypertensive Chinese medicine preparation of described treatment three-hypers type, its primary raw material and weight portion respectively, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Spica Prunellaes, 10 parts of Folium et Ramulus Clerodendri Trichotomis, 60 parts of the Radixs Astragali, 12 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 12 parts, Flos Carthami, 10 parts, Semen Persicae, 10 parts of Medulla Tetrapanaciss, 12 parts of Fructus Liquidambaris, 12 parts of Flos Chrysanthemis, 20 parts, Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Semen Plantaginiss, 30 parts of Fructus Crataegis, 12 parts of Semen Cassiaes, 30 parts of Herba Bidentis Bipinnatae, 20 parts, Radix Glycyrrhizae, 30 parts of Herb Gynostemmae Pentaphylli.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can be by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; Bring into play better drug effect for the each raw material that makes this medicine, carry out special extraction for certain crude drug, as ethanol extraction, these can not be used for limiting the scope of the invention.Active component of the present invention can add various conventional adjuvant required while preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. are prepared into any conventional peroral dosage form with conventional method of Chinese medicinal, as pill, powder, tablet, capsule, oral liquid etc.

Claims (1)

1. the hypertensive Chinese medicine preparation for the treatment of three-hypers type, it is characterized in that: its primary raw material and weight portion respectively, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Spica Prunellaes, 10 parts of Folium et Ramulus Clerodendri Trichotomis, 60 parts of the Radixs Astragali, 12 parts of Radix Scutellariaes, 12 parts of the Cortexs Eucommiae, 12 parts, Flos Carthami, 10 parts, Semen Persicae, 10 parts of Medulla Tetrapanaciss, 12 parts of Fructus Liquidambaris, 12 parts of Flos Chrysanthemis, 20 parts, Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Semen Plantaginiss, 30 parts of Fructus Crataegis, 12 parts of Semen Cassiaes, 30 parts of Herba Bidentis Bipinnatae, 20 parts, Radix Glycyrrhizae, 30 parts of Herb Gynostemmae Pentaphylli.
CN201410127482.7A 2014-03-27 2014-03-27 Traditional Chinese medicinal preparation for treating hypertension Pending CN103919928A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758572A (en) * 2015-04-29 2015-07-08 赵振荣 Medicine for treating phlegm retention obstructing lung type cardiac insufficiency and preparation method thereof
CN106266425A (en) * 2015-06-10 2017-01-04 王世祥 A kind of Chinese medicine formula treating hypertension
CN106668144A (en) * 2016-10-11 2017-05-17 刘艳平 Chinese herbal medicine blood pressure reducing tea and preparation method thereof
CN108686144A (en) * 2017-08-15 2018-10-23 苏建林 It is capable of the preparation method of the oat mixed powder of lower hyperlipidemia, hypertension, hyperglycemia

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758572A (en) * 2015-04-29 2015-07-08 赵振荣 Medicine for treating phlegm retention obstructing lung type cardiac insufficiency and preparation method thereof
CN106266425A (en) * 2015-06-10 2017-01-04 王世祥 A kind of Chinese medicine formula treating hypertension
CN106668144A (en) * 2016-10-11 2017-05-17 刘艳平 Chinese herbal medicine blood pressure reducing tea and preparation method thereof
CN106668144B (en) * 2016-10-11 2020-08-18 刘艳平 Chinese herbal medicine tea for reducing blood pressure and preparation method thereof
CN108686144A (en) * 2017-08-15 2018-10-23 苏建林 It is capable of the preparation method of the oat mixed powder of lower hyperlipidemia, hypertension, hyperglycemia

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