CN103893340A

CN103893340A - Traditional Chinese medicine preparation for treating cold coagulation and blood stasis type oviduct obstructive infertility

Info

Publication number: CN103893340A
Application number: CN201410127296.3A
Authority: CN
Inventors: 王景美
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-03-26
Filing date: 2014-03-26
Publication date: 2014-07-02
Anticipated expiration: 2034-03-26
Also published as: CN103893340B

Abstract

The invention discloses a traditional Chinese medicine preparation for treating cold coagulation and blood stasis type oviduct obstructive infertility. Traditional Chinese medicine pathogenic factors causing oviduct obstruction comprise kidney deficiency, liver-Qi stagnation, phlegm dampness, blood stasis, cold dampness and damp-heat pathogenic factors; traditional Chinese medicine treatment is beneficial to channel warming and cold dispelling and blood stasis removing and collateral dredging. According to the traditional Chinese medicine preparation, a decoction preparation is prepared through decocting traditional Chinese medicines, namely southern evodia fruit, seed of Ajowan-caraway, water pepper fruit, cinnamon tree peel, wild pepper spike, begonia wangii, millettia reticulata, rubia yunnanensis, pretty-leaf silk-vine stem and diversifolious pimpinella, with water; shown by clinical trials, the total effective rate is 94.5%, and the treatment effect is remarkable. During the whole treatment, patients do not suffer from obvious adverse reactions, and the routine examination of blood, urine and stool, cardiograms and the functions of the liver and kidneys all have no obvious change.

Description

A kind of Chinese medicine preparation for the treatment of cold blood stasis type oviduct obstructive sterility

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of cold blood stasis type oviduct obstructive sterility.

Background technology

Oviduct obstructive sterility is one of common clinical, difficult treatment, and its sickness rate is high, and morbidity concealment, how to have caused infertilely while finding disease, brings great hazardness to patient family, society.This disease causes stagnation of blood stasis uterus vessels of the uterus by various paathogenic factors, and " blood stasis " is again new paathogenic factor simultaneously, forms vicious cycle, causes infertility.Modern medicine treatment oviduct obstructive sterility aspect take modus operandi as main, lead to and smooth patient for slight fallopian tube, there is certain treatment clear area, select operation, patient body is had to damage, and increase patient economy burden, for after operation smoothly gestation be still the unknown, selection assisted reproduction does not meet the use standard of assisted reproduction.Modern medicine is not being preponderated aspect Drug therapy oviduct obstructive sterility.In the infertile treatment of obstructive oviduct, Chinese medicine shows good curative effect, also has been widely recognized.Modern pharmacological research confirms, the Chinese medicine that is usually used in treating tubal infertility has effect of sterilization, antiinflammatory, loosen adhesion mostly, and can effectively improve the microcirculation of pelvic tissue, and regulate metabolism, contribute to the absorption of fallopian tube inflammatory lesions, repair the connective tissue of hypertrophy, decompose adhesion, dredging tube chamber, recovers the function of fallopian tube conveying ovum and germ cell, and can effectively improve oviducal fertilization environment, improve conceived probability.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of cold blood stasis type oviduct obstructive sterility.The tcm causa morbi that causes salpingemphraxis is suffered from a deficiency of the kidney, depression of liver-QI, phlegm-damp, blood stasis, cold-damp, damp and hot pathogenic factor.The various causes of disease have formed the pathological product of blood stasis, and stagnation of blood stasis uterus, punching are appointed, vessels of the uterus, collaterals of the uterus, cause obstructed and cause infertile.Blood stasis is paathogenic factor, is again pathological product.Coryza Treated by Syndrome Differentiation cold blood stasis type oviduct obstructive sterility is answered dispelling cold by warming the meridian, eliminating blood stasis and smoothing collaterals.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment cold blood stasis type oviduct obstructive sterility is made up of the Chinese medicine of following weight portion: Folium Evodiae trichotomae 9-15 part, Semen Trachyspermi Ammi 3-5 part, Fructus polygoni hydropiperis 6-10 part, Cortex Cinnamomi Burmannii 3-9 part, Fructus Piperis sarmentosi 1-2 part, Herba Begoniae Cavalerei 9-15 part, Caulis Millettiae Reticulatae 9-15 part, Radix Rubiae Yunnanensis 9-15 part, Caulis Periplocae Calophyllae 9-12 part, Herba pimpinellae diversifoliae 9-15 part.

Preferably, 12 parts of Folium Evodiae trichotomae, 4 parts of Semen Trachyspermi Ammis, 8 parts of Fructus polygoni hydropiperis, 1.5 parts of 6 parts of, Fructus Piperis sarmentosi of Cortex Cinnamomi Burmannii, 12 parts of Herba Begoniae Cavalerei, 12 parts of Caulis Millettiae Reticulataes, 12 parts of Radix Rubiae Yunnanensis, 11 parts of Caulis Periplocae Calophyllaes, 12 parts of Herba pimpinellae diversifoliaes.

Preparation method, by above-mentioned Chinese medicine decocting, is made decoction.

In side: Folium Evodiae trichotomae warming spleen and stomach for dispelling cold, depressed liver-energy dispersing and QI regulating, dispersing the depressed liver-QI for alleviating pain; Semen Trachyspermi Ammi dispel cold dehumidifying, the appetizing pain relieving of regulating the flow of vital energy; Fructus polygoni hydropiperis warming middle-JIAO diuretic, drastically removing blood stasis and resolving static blood; Cortex Cinnamomi Burmannii warming spleen and stomach for dispelling cold, wind-damp dispelling; Fructus Piperis sarmentosi warming middle-JIAO warming the stomach, the circulation of qi promoting of dispeling the wind; The easypro network of Herba Begoniae Cavalerei is invigorated blood circulation, is stimulated the menstrual flow; Caulis Millettiae Reticulatae nourishing blood to expel wind, dredge the meridian passage; Radix Rubiae Yunnanensis blood circulation promoting and enriching, expelling wind and removing dampness; Caulis Periplocae Calophyllae induce sweat cold expelling, wind-expelling pain-stopping; Herba pimpinellae diversifoliae cold expelling blood stasis dispelling, detumescence, eliminate indigestion.

Clinical data

1, the selected 55 routine clinic cases of physical data are cold blood stasis type oviduct obstructive sterility through clinical definite, maximum 39 years old age, minimal ages 22 years old, 29.28 years old mean age, the longest infertile time limit 122 months, the shortest infertile time limit 13 months, the average infertile time limit 39.50 months.

2, diagnostic criteria (1) women of child-bearing age, have normal sexuality after marriage, and bridegroom's or husband's side reproductive function is normal, and contraception is not lived together 1 year and failed the person of becoming pregnant; (2) there are salpingitis tubal medical history or Salpingography to confirm that a side or bilateral obstruction of fallopian tube are smooth, block; (3) under peritoneoscope, confirm that obstruction of fallopian tube is smooth, block; (4) menstruation rule, endocrine detects normal; (5) basal body temperature two-phase.

Dialectical disease: infertile, inferior belly gas pain has creeping chill; Waist sacrum distending pain or cold type of pain discomfort; Profuse leukorrhea, color white matter is rare, coldness of the body with chills, abdominal pain in menstruation increases the weight of, or sees that menstruation delays, measures few, and chromaticness is dark, accompanies clot, and pale tongue is dark, and tongue is white thick or satiny, deep and stringy pulse or stringy and tense pulse.

3, Therapeutic Method patient takes Chinese medicine preparation of the present invention, takes Folium Evodiae trichotomae 12g, Semen Trachyspermi Ammi 4g, Fructus polygoni hydropiperis 8g, Cortex Cinnamomi Burmannii 6g, Fructus Piperis sarmentosi 1.5g, Herba Begoniae Cavalerei 12g, Caulis Millettiae Reticulatae 12g, Radix Rubiae Yunnanensis 12g, Caulis Periplocae Calophyllae 11g, Herba pimpinellae diversifoliae 12g.Decocting extracting juice.Every day 2 times, in decoction being taken warmly 30 minutes ante cibum, after menstruation is clean, first day starts medication, until next menstrual onset is discontinued medication, a menstrual cycle is a course for the treatment of, treats continuously 3 menstrual cycle.

4, criterion of therapeutical effect is evaluated with reference to " obstetrics and gynecology ".(1) clinical cure: become pregnant or do not become pregnant in December after treatment but hysterosalpingography confirms that bilateral fallopian tube is all unobstructed, contrast agent disperse is normal.(2) effective: though do not become pregnant after treatment, patient clinical performance and the auxiliary examination of being correlated with are all alleviated to some extent; Contrast agent disperse is normally unobstructed to be improved or to lead to and not smooth, and contrast agent disperse is bad, or bilateral salpingemphraxis becomes the rear one-sided obstruction for the treatment of before treatment.(3) invalid: after treatment, do not become pregnant and clinical manifestation and auxiliary examination all unchanged.Radiography shows that tubal patency degree is unchanged.

5, wherein clinical recovery 24 examples (43.6%) of the routine patient of therapeutic outcome 55, effective 28 examples (50.9%), invalid 3 examples (5.5%), total effective rate 94.5%, evident in efficacy.In whole therapeutic process, there is not obvious untoward reaction in patient, and blood, urine, stool routine examination, electrocardiogram and liver, renal function have no significant change.

The specific embodiment

Embodiment mono-: take Folium Evodiae trichotomae 12g, Semen Trachyspermi Ammi 4g, Fructus polygoni hydropiperis 8g, Cortex Cinnamomi Burmannii 6g, Fructus Piperis sarmentosi 1.5g, Herba Begoniae Cavalerei 12g, Caulis Millettiae Reticulatae 12g, Radix Rubiae Yunnanensis 12g, Caulis Periplocae Calophyllae 11g, Herba pimpinellae diversifoliae 12g, become decoction by traditional method decocting.

Embodiment bis-: take Folium Evodiae trichotomae 15g, Semen Trachyspermi Ammi 3g, Fructus polygoni hydropiperis 10g, Cortex Cinnamomi Burmannii 3g, Fructus Piperis sarmentosi 2g, Herba Begoniae Cavalerei 9g, Caulis Millettiae Reticulatae 15g, Radix Rubiae Yunnanensis 9g, Caulis Periplocae Calophyllae 12g, Herba pimpinellae diversifoliae 9g, become decoction by traditional method decocting.

Embodiment tri-: take Folium Evodiae trichotomae 9g, Semen Trachyspermi Ammi 5g, Fructus polygoni hydropiperis 6g, Cortex Cinnamomi Burmannii 9g, Fructus Piperis sarmentosi 1g, Herba Begoniae Cavalerei 15g, Caulis Millettiae Reticulatae 9g, Radix Rubiae Yunnanensis 15g, Caulis Periplocae Calophyllae 9g, Herba pimpinellae diversifoliae 15g, become decoction by traditional method decocting.

Claims

1. treat a Chinese medicine preparation for cold blood stasis type oviduct obstructive sterility, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Folium Evodiae trichotomae 9-15 part, Semen Trachyspermi Ammi 3-5 part, Fructus polygoni hydropiperis 6-10 part, Cortex Cinnamomi Burmannii 3-9 part, Fructus Piperis sarmentosi 1-2 part, Herba Begoniae Cavalerei 9-15 part, Caulis Millettiae Reticulatae 9-15 part, Radix Rubiae Yunnanensis 9-15 part, Caulis Periplocae Calophyllae 9-12 part, Herba pimpinellae diversifoliae 9-15 part.

2. a kind of Chinese medicine preparation for the treatment of cold blood stasis type oviduct obstructive sterility as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: 12 parts of Folium Evodiae trichotomae, 4 parts of Semen Trachyspermi Ammis, 8 parts of Fructus polygoni hydropiperis, 1.5 parts of 6 parts of, Fructus Piperis sarmentosi of Cortex Cinnamomi Burmannii, 12 parts of Herba Begoniae Cavalerei, 12 parts of Caulis Millettiae Reticulataes, 12 parts of Radix Rubiae Yunnanensis, 11 parts of Caulis Periplocae Calophyllaes, 12 parts of Herba pimpinellae diversifoliaes.