CN103893309A - Medicament for treating rheumatoid arthritis - Google Patents

Abstract

The invention discloses traditional Chinese medicine for treating diseases, and particularly discloses a medicament prepared from Chinese herbal medicine raw materials for treating rheumatoid arthritis. The medicament consists of the following components by weight: 10-20g of Chinese angelica, 10-20g of cortex eucommiae, 10-20g of yellowmouth dutchmanspipe root, 10-20g of clematis root, 10-20g of large-leaved gentian, 10-20g of medicinal cyathula root, 10-20g of pawpaw, 10-20g of giant knotweed, 8-12g of garter snake, 8-12g of frankincense, 8-12g of myrrh, 15-25g of epimedium herb and 3-7g of common monkshood mother root. A preparation method of the medicament comprises the following steps: putting 5g of common monkshood mother root into an earthen pot, adding 500ml of water for decocting, boiling together with the remaining medicinal materials over big fire, then decocting over soft fire for 40 minutes, and filtering out 250ml of liquid medicament by using a filter screen; and adding water again, decocting for 20 minutes and then filtering out 250 ml of liquid medicament and combining the liquid medicaments decocted in two times to obtain a decoction. The decoction product contains multiple types of medicinal materials, and is strict in composition, long in duration of medicinal effect and remarkable curative effect.

Description

A kind of medicine for the treatment of rheumatoid arthritis

Technical field: the present invention relates to a kind of Chinese medicine for the treatment of disease, a kind of medicine for the treatment of rheumatoid arthritis that specifically utilizes Chinese herbal medicine to prepare for raw material.

Background technology: rheumatoid arthritis is the difficult problem on our times medical science, is medically called not dead cancer.According to incompletely statistics, there is in the world more than 1/3rd population to suffer from various rheumatism, wherein have 80% the chronic disease that transfers to.Rheumatoid arthritis is just general as cat fever, emphasis is coastal area, mountain region and extremely frigid zones, perplexing for a long time people's production and life always, bring great misery to extensive patients, the lighter causes arthralgia, the akinesia of patient's rainy weather, cold season, severe one causes lifelong maimed person, can't take care of oneself.Many people therefore produce other complication, threat to life.World Health Organization (WHO) is called after world joint buring sun on annual October 12 for this reason, and 2000-2010 is defined as to B&J disease international control 10 years.At present, in global range, also do not effect a radical cure the specific drug of rheumatoid arthritis, and the medicine major part for the treatment of now rheumatoid arthritis disease has side effect, and gastrointestinal tract is had to stimulation, Immunosuppression function, easily recurrence after drug withdrawal.And price is more expensive, therapeutic effect is undesirable and can not effect a radical cure.

Summary of the invention: object of the present invention has just been to provide that a kind of prescription is rigorous and medicine source is wide, the long and a kind of medicine for the treatment of rheumatoid arthritis evident in efficacy of duration of efficacy.

The present invention for the technical scheme that realizes above-mentioned order ground and adopt is: its prescription is: Radix Angelicae Sinensis 10-20g, Cortex Eucommiae 10-20g, Radix Stephaniae Tetrandrae 10-20g, Radix Clematidis 10-20g, Radix Gentianae Macrophyllae 10-20g, Radix Cyathulae 10-20g, Fructus Chaenomelis 10-20g, Rhizoma Polygoni Cuspidati 10-20g, Zaocys 8-12g, Olibanum 8-12g, Myrrha 8-12g, Herba Epimedii 15-25g, Radix Aconiti 3-7g; Its preparation method adds water 500ml for Radix Aconiti 5g is put into marmite, boils 80 minutes, then together puts into medicine pot with all the other medicines that soak 1 hour, water and exceed medicine 5cm, first uses big fire boiled, then boils after 40 minutes with little fire, medicinal liquid is leached with filter screen, endure out medicinal liquid 250ml first; Again add water and exceed the medicine 2.5cm after boiling first, re-starting and boil, boiling after 20 minutes time, then leaching medicinal liquid 250ml; Then the medicinal liquid boiling for twice is put together, decoction, finally pack packs warehouse-in.

The technical scheme that the present invention solves is to rheumatoid arthritis and the pathogenetic understanding of complication and Therapeutic Principle based on motherland's medical science, achieve with reference to modern pharmacological research, from motherland's medical treasure-house, filter out several natural plants, by theory of Chinese medical science prescription, skim the cream off milk, make its alleviation and radical cure rheumatoid arthritis disease.

Theory of Chinese medical science thinks, rheumatoid arthritis is not that people imagine to such an extent that is petty die-hard, is difficult to cure, and just can reach the object of radical cure by endo-medicine, and medicine has the speciality of individual character, and there is gregarious magical effect side, and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs gets final product in medication.Rheumatoid arthritis belongs to the category of impediment syndrome, and the occurrence cause of primary disease is mainly by positive QI-insufficiency, experiences the heresy of wind, cold, wet, heat, and impatency meridians, due to QI-blood circulation is not smooth.As " class card sanction-arthromyodynia " institute's cloud: " wind and cold is wet attacks in taking advantage of a weak point in opponent's defence for all numbness ... good in the Wei Xianxu of battalion, interspaces of skin and muscles being loose.Healthy energy is hindered by evil, can not declare row, thereby be detained, and QI and blood is solidifying puckery, forms for a long time numbness ".To the treatment of primary disease, should be with strong liver the kidney invigorating, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, dispersing swelling and dissipating binds, removing obstruction in the collateral to relieve pain is method.Radix Angelicae Sinensis in this prescription, Olibanum, Myrrha promoting blood circulation and stopping pain, detumescence and promoting granulation; Radix Aconiti wind-damp dispelling, dispersing cold for relieving pain; The Cortex Eucommiae, Radix Cyathulae, Herba Epimedii invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, promoting blood circulation profit joint; Fructus Chaenomelis, river Macrophylla, Radix Stephaniae Tetrandrae, Radix Clematidis relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and removing dampness and stopping numbness pain; Zaocys dispelling, collateral-activating, has the effect of " the deep wind of searching "; Rhizoma Polygoni Cuspidati has clearing away heat-damp and promoting diuresis, the effect of the analgesic therapy of invigorating blood circulation.Under interacting, concoct all medicines by said medicine, and guide all medicines sick institute that goes directly.

Preparation of the present invention is oral medicine, and attending scope is mainly applicable to rheumatoid arthritis coldheat complex, the arthromyodynia of congestion resistance network, be muscle or arthralgia, fix and do not move, twinge or sore spot tenderness, local heating of touching but conscious fear of cold, or touch not hot but conscious heating, whole body thermal image is aobvious, local swelling can have scleroma, or sees ankylosis deformity, joint stuffiness, amyotrophy, dark tongue quality or have ecchymosis, yellow fur or white, or HUANGBAI(sic) is double mutually, wiry and frequent pulse or heavy carefully puckery.There is wind and heat dispersing, diuretic dampness, the function of booster immunization effect, is generally suitable for rheumatoid arthritis disease, and has healing effect.Rheumatoid arthritis is there is to the effect that significantly slows down PD.

The invention has the beneficial effects as follows: medicine of the present invention shows there is following advantages through clinical practice result:

1, preparation of the present invention, has the outstanding effect of suiting the medicine to the illness to affected part, and the distinguishing mark that all local arthralgias causing because of wind, cold, wet and inflammation can show dyschromasia, can effect a radical cure to the ill.

2, preparation of the present invention, duration of efficacy is long, once suit the medicine to the illness, will carry out continual effect to wind, cold, wet factor always, as long as disease is not dispelled, drug effect just continues always.

3, the present invention prepares the Chinese herbal medicine needing and draws materials and facilitate simple and easyly, is applicable to artificial establishing in large scale, and output is high, and product mass-energy guarantees, thereby cost is low, is conducive to extensive popularization.

4, the present invention has no side effect, safe and reliable.Wherein Radix Aconiti removes through special handling toxicity, can not work the mischief to human body and vital movement.

5, the present invention is owing to having adopted various Chinese crude drugs and meticulous special processing process, and its goods include multi-medicament, and prescription is rigorous, and technique is simple, and dosage form is various.

The specific embodiment: embodiment 1: its prescription is: Radix Angelicae Sinensis 10-20g, Cortex Eucommiae 10-20g, Radix Stephaniae Tetrandrae 10-20g, Radix Clematidis 10-20g, Radix Gentianae Macrophyllae 10-20g, Radix Cyathulae 10-20g, Fructus Chaenomelis 10-20g, Rhizoma Polygoni Cuspidati 10-20g, Zaocys 8-12g, Olibanum 8-12g, Myrrha 8-12g, Herba Epimedii 15-25g, Radix Aconiti 3-7g; Its preparation method adds water 500ml for Radix Aconiti 5g is put into marmite, boils 80 minutes, then together puts into medicine pot with all the other medicines that soak 1 hour, water and exceed medicine 5cm, first uses big fire boiled, then boils after 40 minutes with little fire, medicinal liquid is leached with filter screen, endure out medicinal liquid 250ml first; Again add water and exceed the medicine 2.5cm after boiling first, re-starting and boil, boiling after 20 minutes time, then leaching medicinal liquid 250ml; Then the medicinal liquid boiling for twice is put together, decoction, finally pack packs warehouse-in.

Embodiment 2: its prescription is: Radix Angelicae Sinensis 15g, Cortex Eucommiae 15g, Radix Stephaniae Tetrandrae 15g, Radix Clematidis 15g, Radix Gentianae Macrophyllae 15g, Radix Cyathulae 15g, Fructus Chaenomelis 15g, Rhizoma Polygoni Cuspidati 15g, Zaocys 10g, Olibanum 10g, Myrrha 10g, Herba Epimedii 20g, Radix Aconiti 5g; Its preparation method adds water 500ml for Radix Aconiti 5g is put into marmite, boils 80 minutes, then together puts into medicine pot with all the other medicines that soak 1 hour, water and exceed medicine 5cm, first uses big fire boiled, then boils after 40 minutes with little fire, medicinal liquid is leached with filter screen, endure out medicinal liquid 250ml first; Again add water and exceed the medicine 2.5cm after boiling first, re-starting and boil, boiling after 20 minutes time, then leaching medicinal liquid 250ml; Then the medicinal liquid boiling for twice is put together, decoction, finally pack packs warehouse-in.

Embodiment 3: criterion of therapeutical effect of the present invention is:

Clinical cure: symptom, sign disappear completely, and walking is normal, and erythrocyte sedimentation rate is normal, rheumatoid factor negative.

Effective: symptom, sign are clearly better completely, erythrocyte sedimentation rate declines 60%, and morning, deadlock, gait were improved, rheumatoid factor negative.

Invalid: symptom, sign are without improvement, and erythrocyte sedimentation rate, rheumatoid factor are without improvement.

Embodiment 4: finished medicines prepared by the present invention is liquid preparation, belongs to oral medicine.When use, can divide and sooner or later service once, 250 grams of dosing, take 2 months continuously, can cure or take a turn for the better.

Embodiment 5: through diagnoses and treatment proves to patient clinical, this preparation, to rheumatoid arthritis disease, has and significantly slows down the effect of PD and cure effect.

Clinical 42 examples for the treatment of altogether of this preparation, through 2 months medication treatments, clinical cure 19 examples accounted for 45.2%, and effective 21 examples account for 50%, and invalid 2 examples account for 4.8%, total effective rate 95.2%.For effective patient, can under physician guidance, continue to take medicine according to the state of an illness, until cure, nonresponder's dialectical Analyses, finds new treatment approach.

Prove through clinical diagnosis treatment, this medicine is pure Chinese herbal medicine type for oral administration, effect stability, safe without toxic side effect.

Embodiment 6: prove through several patient clinical diagnoses and treatment:

1, patient, man, Earthquake of Anyang station in Henan people, workman, 47 years old, suffers from rheumatoid arthritis.Fall ill 1999 time, overcast and rainy both legs can not be stretched in the wrong, pain redness, the fruit of failing to respond to any medical treatment everywhere.Within 2010, treat to here, March 16 medication 250ml for the first time, double knee joint position pain relief after ten days.Medication for the second time on April 16, after two months, meets rainy weather, painless feel, and under normal weather conditions, no abnormalities feel.

2, patient, man, people from Puyang oilfield of Henan, retired worker, 85 years old, the summer in 1963 was felt double knee joint pain, constantly the medicine does no good in centre.Arthroncus in 1980, nineteen ninety-five both legs deformity of knee-joint, right lower limb knee joint introversion.Within 2000, show through hospital's X-ray, be diagnosed as rheumatoid arthritis.On May 10th, 2011 starts this soothing the channels and quicking the network vessels decoction formulation, dosage 250ml, and rain evening May 16, and only sensation is heavy, not feels pain.Feel comfortable strong morning May 22.Medication in afternoon on May 26 250ml, June 2 rained, and agents area is without heavy, pain.Medication in afternoon on June 10 250ml, in medication process, joint part has the heat sensation that rises.Treat after one month, both legs can walk, by bike.

3, patient, people from Hebi, Henan, civil servant, 45 years old, female, suffered from rheumatoid arthritis for 1981.Within 1998, lumbar vertebra is tetanic successively, and natural torsion is lost, and is arc, and chest is comforted the back of the body and can not directly be risen.Start medication on August 15th, 2012, thoracic vertebra is treated continuous use once a day, a drug 250ml.Continuous use 20 days, back is with pruritus.JIUYUE after 5 days between the each vertebra of chest and back tetanic joint mobilization can hear sound, thoracic dorsal can be straight and upright, waist is flexible, and sensation is strong, when sitting and lying, the sense of buttocks tenderness alleviates.JIUYUE continues medication on 15th, and October 15, pain was not obvious, after this discontinued medication, and adhered to restorative exercise.

Claims (2)

1. treat the medicine of rheumatoid arthritis for one kind, it is characterized in that its prescription is: Radix Angelicae Sinensis 10-20g, Cortex Eucommiae 10-20g, Radix Stephaniae Tetrandrae 10-20g, Radix Clematidis 10-20g, Radix Gentianae Macrophyllae 10-20g, Radix Cyathulae 10-20g, Fructus Chaenomelis 10-20g, Rhizoma Polygoni Cuspidati 10-20g, Zaocys 8-12g, Olibanum 8-12g, Myrrha 8-12g, Herba Epimedii 15-25g, Radix Aconiti 3-7g; Its preparation method adds water 500ml for Radix Aconiti 5g is put into marmite, boils 80 minutes, then together puts into medicine pot with all the other medicines that soak 1 hour, water and exceed medicine 5cm, first uses big fire boiled, then boils after 40 minutes with little fire, medicinal liquid is leached with filter screen, endure out medicinal liquid 250ml first; Again add water and exceed the medicine 2.5cm after boiling first, re-starting and boil, boiling after 20 minutes time, then leaching medicinal liquid 250ml; Then the medicinal liquid boiling for twice is put together, decoction, finally pack packs warehouse-in.

2. a kind of medicine for the treatment of rheumatoid arthritis according to claim 1, it is characterized in that its prescription is: Radix Angelicae Sinensis 15g, Cortex Eucommiae 15g, Radix Stephaniae Tetrandrae 15g, Radix Clematidis 15g, Radix Gentianae Macrophyllae 15g, Radix Cyathulae 15g, Fructus Chaenomelis 15g, Rhizoma Polygoni Cuspidati 15g, Zaocys 10g, Olibanum 10g, Myrrha 10g, Herba Epimedii 20g, Radix Aconiti 5g; Its preparation method adds water 500ml for Radix Aconiti 5g is put into marmite, boils 80 minutes, then together puts into medicine pot with all the other medicines that soak 1 hour, water and exceed medicine 5cm, first uses big fire boiled, then boils after 40 minutes with little fire, medicinal liquid is leached with filter screen, endure out medicinal liquid 250ml first; Again add water and exceed the medicine 2.5cm after boiling first, re-starting and boil, boiling after 20 minutes time, then leaching medicinal liquid 250ml; Then the medicinal liquid boiling for twice is put together, decoction, finally pack packs warehouse-in.