CN103861043A - External medicament of traditional Chinese medicine for treating liver cirrhosis - Google Patents

Abstract

The invention discloses an external medicament of a traditional Chinese medicine for treating liver cirrhosis, which is low in cost, ideal in treatment effect and free of toxic and side effects. The external medicament of the traditional Chinese medicine for treating liver cirrhosis is characterized by comprising the following crude medicaments by weight ratio: leech, radix stephaniae tetrandrae, schisandra chinensis, rhizoma sparganii, curcuma zedoary, root of common peony, bighead atractylodes rhizome, liquorice and borneol being (3-6):(3-6):(3-6):(3-6):(3-6):(1-3):(1-3):(1-3):(0-1).

Description

The Chinese medicine external medicine for the treatment of liver cirrhosis

Technical field

The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine external medicine for the treatment of liver cirrhosis.

Background technology

China's liver cirrhosis patient is numerous, except the viral hepatitis such as HBV, HCV liver cirrhosis, also has alcoholic cirrhosis, medicine liver liver cirrhosis etc.One of the common disease of China and main Death causes.No matter doctor trained in Western medicine or the traditional Chinese medical science at present, there is no desirable treatment measure.The liver cirrhosis causing for a variety of causes is at present except etiological treatment, and wholistic therapy not yet reaches satisfied effect, and the Western medicine of anti-cirrhosis treatment to exist curative effect not remarkable, erious adverse reaction, the shortcoming such as expensive.

Chinese medicine compound and the Chinese patent medicine of the treatment of clinical research at present liver cirrhosis are more.Liver cirrhosis mostly is development of chronic hepatitis, and protracted inflammation is difficult, needs long-term treatment, and the long course of therapy of application Chinese medicine decoction is very inconvenient, and patient should be poor from property.Moreover long-term taking Chinese patent medicine can be because partially there are various side effect in the long-term mistake of the property of medicine, when Cirrhotic Portal Hypertension, gastro-intestinal congestion, how with portal hypertension gastopathy, oral drugs effect is not good enough, even damages healthy energy, cuts down damage of the spleen stomach.The high violent removing blood stasis medicine of Long-term Oral there will be the treating the liver impairment of the spleen, the situation that treating the liver is impairment of the kidney.

Chinese traditional medicine point plaster therapy is to mediate a settlement viscera theory as theoretical basis taking science of arteries and veins, according to the needs of different syndromes, select corresponding medicine to adjust cream, sticked on treatment acupuncture point, cover and fix with gauze, adhesive plaster etc., to reach the object of prevention, treatment disease.The external treatment well-known doctor Wu Shiji of the Qing Dynasty in " reason Perish the parallel prose ", brilliantly point out " reason of outer disease be in the reason of disease; The medicine of external treatment that is the medicine for the treatment of by oral administration of medicines; Different person, a method ear!

At present Chinese traditional medicine point plaster treatment cirrhotic ascites is had to clinical report, but less for the research that improves hepatic fibrosis index, reduction liver hardness number, control liver cirrhosis progress aspect.Zhang Bo etc. have carry out soft liver cream apply ointment or plaster treatment hepatic fibrosis after hepatitis treatment clinical research.Its soft liver cream is mainly by ingredients such as Pulvis Fumi Carbonisatus, SEMEN IMPATIENTIS, Fructus Ailanthi, Rhizoma Acori Graminei, raw Carapax Trionycis, the Radix Rehmanniae, Fructus Psoraleae, Ootheca Mantidis, Radix Angelicae Sinensis, Olibanum, Myrrha, Concha Ostreae, Scolopendra, Semen Persicae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Et Rhizoma Rhei, Hirudo, Arisaema Cum Bile, Radix Aconiti Kusnezoffii, Radix Curcumae, Radix Kansui, Fructus Trichosanthis.Make unguentum according to Chinese medicine processing technique, spread out on 8 cm × 8 cm byssuss, ointment diameter 3 cm, every ointment weighs 3 g.Choose point cv 9, hepatitis cave (experience cave is positioned at right side point lr 14 level other 3 cm that open to the right) and bl cave, right side.First, by local skin warm water cleaning, ointment is roastingization on slow fire, is applied on selected acupuncture point after slightly cool.Add and apply contracting spleen cave (experience cave, left side point lr 14 is flat axil median line infall left) with splenomegaly person.Within every 5 days, changing dressings 1 time, 2 months is 1 course for the treatment of.There is following problem in its technology: 1, its prescription complexity, and expensive, be unfavorable for patient's prolonged application and clinical expansion.2, plaster sticks insecurely, is easy to away cream pollution clothes.3, applying method complexity, is unfavorable for clinical expansion.4, clinical verification lacks liver hardness elastic index.

Summary of the invention

The object of this invention is to provide a kind of with low cost, therapeutic effect is desirable, the Chinese medicine external medicine of the treatment liver cirrhosis that has no side effect.

To achieve these goals, the present invention is by the following technical solutions:

Treat a Chinese medicine external medicine for liver cirrhosis, it is characterized in that comprising each crude drug of following weight ratio example: Hirudo, Radix Stephaniae Tetrandrae, Fructus Schisandrae Chinensis, Rhizoma Sparganii, Rhizoma Curcumae, Radix Paeoniae Rubra, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Borneolum Syntheticum=3-6:3-6: 3-6:3-6:3-6:1-3:1-3:1-3:0-1.

The Chinese medicine external medicine of above-mentioned treatment liver cirrhosis, comprises each crude drug of following weight ratio example: Hirudo, Radix Stephaniae Tetrandrae, Fructus Schisandrae Chinensis, Rhizoma Sparganii, Rhizoma Curcumae, Radix Paeoniae Rubra, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Borneolum Syntheticum=4:4:4:4:4:2:2:1:1.

The Chinese medicine external medicine of above-mentioned treatment liver cirrhosis, makes powder according to Chinese medicine processing method.

The application of a kind of described Chinese medicine external medicine in preparation treatment liver cirrhosis.

Pharmacology of the present invention is as follows:

Radix Stephaniae Tetrandrae: hardship, cold.Return bladder, lung meridian.Function cures mainly inducing diuresis to remove edema, wind-expelling pain-stopping.For edema beriberi, dysuria, eczema sore, rheumatic arthralgia; Hypertension.

Hirudo: salty, bitter, flat; Poisonous.Return Liver Channel.Function with cure mainly removing blood stasis, removing blood stasis, stimulates the menstrual flow.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, traumatic injury.

Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Function with cure mainly convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.

Rhizoma Sparganii: pungent, bitter, flat.Return liver, spleen channel.Function with cure mainly removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.

Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.Function with cure mainly circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For  abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.

Radix Paeoniae Rubra: hardship, is slightly cold.Return Liver Channel.Function with cure mainly clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, { note of the ancient Chinese } abdominal mass stomachache, injury from falling down, carbuncle skin infection.

The Rhizoma Atractylodis Macrocephalae: warm in nature, bitter in the mouth, sweet.Cure mainly invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention have loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.

Radix Glycyrrhizae: have removing toxic substances, eliminate the phlegm, pain relieving, spasmolysis.Invigorating the spleen and replenishing QI, grows and coughs lung moistening, emergency removing toxic substances, mediation hundred medicines.

Hirudo removing blood stasis in medicine of the present invention, removing blood stasis, stimulates the menstrual flow, dredging water passages.Be apt to control blood-retention, lump in the abdomen, gathers; Rhizoma Sparganii, Rhizoma Curcumae mutual reinforcement between are use, instrumental ensemble the removing blood stasis silt of dispelling, promoting the circulation of QI to relieve pain, the merit of removing food stagnancy ， Zhi WEIJIA.Radix Paeoniae Rubra can clots absorbing, pain relieving, and removing heat from blood, detumescence, arrogates to oneself and controls the stagnant amenorrhea of the stasis of blood, and hernia abdominal mass is gathered, stomachache, hypochondriac pain.Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI, dampness diuretic, is to get the meaning that it " sees the disease tonifying the spleen in the ban of liver ".The medicine that prevents removing blood stasis injures taste.Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Borneolum Syntheticum heat-clearing and toxic substances removing, promotes Drug Percutaneous Absorption.All for adjuvant drug vinegar sour in the mouth slightly warm in nature can draw all medicines, to enter Liver Channel be for making medicine, and all medicines share blood stasis dispelling worry without hematozemia with nourishing blood with executing that coordination of potent and mild therapies is invigorated blood circulation, and circulation of qi promoting is again without the fraud of impairment of YIN.Make the without hindrance merit of playing altogether dispersing the stagnated liver-QI and dredging collateral of the unimpeded blood of venation.The external application of Chinese medicine both can stimulating acupoint, strengthened immunologic function, had again circulation of qi promoting dissipating blood stasis effect, can make effective ingredient by the meridians disease institute that goes directly, and reached effect of depressed liver-energy dispersing and QI regulating blood circulation promoting and blood stasis dispelling, hard masses softening and resolving.

Beneficial effect of the present invention: the treatment for liver cirrhosis disease patient is very effective, various crude drug are mutually coordinated can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, medicine of the present invention has no side effect in addition, expense is lower.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is described in further details, following explanation is only exemplary, does not limit protection scope of the present invention.

Embodiment 1

Ingredients: Hirudo 20g, Radix Stephaniae Tetrandrae 20g, Fructus Schisandrae Chinensis 20g, Rhizoma Sparganii 20g, Rhizoma Curcumae 20g, Radix Paeoniae Rubra 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Glycyrrhizae 5g, Borneolum Syntheticum 5g.

Preparation method: medicine is taken by proportion speed, be crushed to micron order through pulverizing mill, insert air-tight bottle for subsequent use after 200 mesh sieves filter.

Usage and consumption: get 5g vinegar furnishing pasty state at every turn and be filled in the acupoint plaster of internal diameter 2.0cm, select two acupuncture points at every turn, alternately spread on SHENQUE acupoint, bl cave, point lr 14, tsu san li, point lr 13, the next day applies 12h, 12 months courses for the treatment of for 1 time at every turn.

Embodiment 2

Ingredients: Hirudo 12g, Radix Stephaniae Tetrandrae 15g, Fructus Schisandrae Chinensis 9g, Rhizoma Sparganii 18g, Rhizoma Curcumae 12g, Radix Paeoniae Rubra 7.5g, Rhizoma Atractylodis Macrocephalae 6g, Radix Glycyrrhizae 9g, Borneolum Syntheticum 3g.

Preparation method: make unguentum by Mel or Rhizoma Zingiberis Recens juice or Chinese medicine processing technique, disinfection final vacuum is enclosed in acupoint plaster, and after patient's cleaning skin, opening protecting film can stick immediately.Consumption is with embodiment 1.

Embodiment 3

Ingredients: Hirudo 10, Radix Stephaniae Tetrandrae 18, Fructus Schisandrae Chinensis 18, Rhizoma Sparganii 18 g, Rhizoma Curcumae 18 g, Radix Paeoniae Rubra 3g, Rhizoma Atractylodis Macrocephalae 9g, Radix Glycyrrhizae 3g

Preparation method and usage and dosage are with embodiment 1.

Clinical data

One, suffer from the people of liver cirrhosis male 12 examples, women's 8 examples for 20 of clinical treatment.

Two, clinical manifestation: limb is soft weak, weak from head to foot; Abdominal distention, nauseating, upper abdomen dull pain; Hepatomegaly, quality are partially hard; Yellow cellulitis, anemia or have bleeding tendency; There are liver palm, spider angioma, cutaneous pigmentation and edema etc.

Three, curative effect determinate standard:

Cure: weak disappearance, limbs are strong; Abdominal distention, feel sick, upper abdomen dull pain obviously alleviates; Anemia and hepatic face are obviously alleviated, and face is wise man in vain, occurs ruddy; Edema disappears; Hepatic fibrosis Index for examination is obviously alleviated.

Take a turn for the better: with it energetically; Abdominal distention, feel sick, vomiting, anemia, edema etc. are slow to some extent.

Invalid: before treatment.

When clinical experiment, utilize medicine of the present invention alternately to spread on SHENQUE acupoint, bl cave, point lr 14, tsu san li, point lr 13, the next day, applies 12h, 12 months courses for the treatment of for 1 time at every turn.

Four, therapeutic outcome

Table 1:20 name patient with liver cirrhosis curative effect table

In table 1, show that medicine total effective rate of the present invention reaches 95%, therapeutic effect is good.

Claims (4)

1. treat a Chinese medicine external medicine for liver cirrhosis, it is characterized in that comprising each crude drug of following weight ratio example: Hirudo, Radix Stephaniae Tetrandrae, Fructus Schisandrae Chinensis, Rhizoma Sparganii, Rhizoma Curcumae, Radix Paeoniae Rubra, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Borneolum Syntheticum=3-6:3-6: 3-6:3-6:3-6:1-3:1-3:1-3:0-1.

2. treat according to claim 1 the Chinese medicine external medicine of liver cirrhosis, it is characterized in that comprising each crude drug of following weight ratio example: Hirudo, Radix Stephaniae Tetrandrae, Fructus Schisandrae Chinensis, Rhizoma Sparganii, Rhizoma Curcumae, Radix Paeoniae Rubra, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Borneolum Syntheticum=4:4:4:4:4:2:2:1:1.

3. Chinese medicine external medicine according to claim 1 and 2, it is characterized in that: make powder according to Chinese medicine processing method.

4. the application of the Chinese medicine external medicine described in a claim 1 or 2 in preparation treatment liver cirrhosis.