CN103860828B - Medicament for treating traumatic injuries and fracture and preparation method thereof - Google Patents

Medicament for treating traumatic injuries and fracture and preparation method thereof Download PDF

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CN103860828B
CN103860828B CN201410125521.XA CN201410125521A CN103860828B CN 103860828 B CN103860828 B CN 103860828B CN 201410125521 A CN201410125521 A CN 201410125521A CN 103860828 B CN103860828 B CN 103860828B
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fracture
medicine
medicament
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traumatic injury
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CN103860828A (en
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王荣
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Abstract

The invention relates to the field of traditional Chinese medicines and particularly relates to a medicament for treating traumatic injuries and fracture and a preparation method thereof. The medicament for treating traumatic injuries and fracture comprises an external-application agent including the following components in parts by weight: 26-30 parts of leaves of williams elder twig, 20-30 parts of roots and barks of the williams elder twig, 26-30 parts of leaves of the williams elder twig, 5-10 parts of cuttlebones, 3-5 parts of paris polyphylla and 3-5 parts of tubers and roots of Aconitum kongboense. The medicament not only can treat traumatic injuries, but also can treat fracture; while being externally applied for use, the medicament is good in curative effect on diseases, and short in treatment cycle. A clinical test proves that the medicament can become effective for treating common traumatic injuries within about 3 days, the common traumatic injuries can be healed within 3-7 days, and the fracture is almost healed within 15-25 days. Besides, the medicament disclosed by the invention has a special effect on postoperative bone nonunion complication of fracture, and has a curative effect on rheumatism and effusion of knee joint. And moreover, the materials are Chinese herbal medicines and free of toxic and side effect. Besides, the preparation method is simple, so that patients can prepare the medicament by themselves.

Description

Treatment traumatic injury, medicine of fracture and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, in particular to treatment traumatic injury, the medicine of fracture and preparation method thereof.
Background technology
The medicine being presently used for treating traumatic injury, fracturing has many kinds, wherein based on Chinese medicine.In correlation technique, Some treatment traumatic injuries, either external application class should take class orally although therapeutic effect to the medicine of fracture, but treatment cycle mistake Long, it is typically necessary 1 month or the longer time.
Content of the invention
It is an object of the invention to provide treatment traumatic injury, medicine of fracture and preparation method thereof, above-mentioned to solve Problem.
Provide a kind of medicine treated traumatic injury, fracture in an embodiment of the present invention, including by following component group The externally dressing becoming:
By weight, leaf 26-30 part that gagger dissipates, root skin 20-30 part that gagger dissipates, leaf 26-30 part of powdered medicine for coaptation, Cuttlebone 5-10 part, Paris polyphylla 3-5 part, Radix Aconiti Kongboensis 3-5 part.
Further, by weight, leaf 26-28 part that gagger dissipates, root skin 25-30 part that gagger dissipates, the leaf of powdered medicine for coaptation Sub- 26-30 part, cuttlebone 6-10 part, Paris polyphylla 3-5 part, Radix Aconiti Kongboensis 3-5 part.
Further, by weight, leaf 27-30 part that gagger dissipates, root skin 20-24 part that gagger dissipates, the leaf of powdered medicine for coaptation Sub- 26-28 part, cuttlebone 5-7 part, Paris polyphylla 3-5 part, Radix Aconiti Kongboensis 3-5 part.
Further, by weight, leaf 26-30 part that gagger dissipates, root skin 20-30 part that gagger dissipates, the leaf of powdered medicine for coaptation Sub- 29-30 part, cuttlebone 5-10 part, Paris polyphylla 3-4 part, Radix Aconiti Kongboensis 3-4 part.
Additionally provide above-mentioned treatment traumatic injury, the preparation method of the medicine of fracture in an embodiment of the present invention, including The following step:
Step A:According to formula, respectively by root skin scattered to the scattered leaf of gagger, gagger, the leaf of powdered medicine for coaptation, cuttlebone, weight Building and Radix Aconiti Kongboensis, grind into powder, remix, obtain raw mixture;
Step B:Raw mixture is made externally dressing.
Further, step B further includes:
Step B1:Add boiling water in flour, be stirred for, obtain efficacy-enhancing ingredient;
Step B2:By efficacy-enhancing ingredient and raw mixture mixing, add boiling water, the traumatic injury that obtains medical treatment, the medicine of fracture.
Further, in step B2, also include after adding boiling water:Add alcohol.
Further, in step B1, also include after stirring:Add honey.
The treatment traumatic injury of the above embodiment of the present invention, the medicine of fracture are made up of six kinds of Chinese medicines, and this medicine both may be used To treat traumatic injury, fracture can be treated again, and when external application uses, good to the therapeutic effect of above two disease, control Treat cycle is short.Clinical tests prove that, using drug therapy treatment traumatic injury and the fracture of the present invention, general traumatic injury 3 Can take effect about it, be almost recovered within 3-7 days, fracture is almost recovered for 15 to 25 days.In addition, the medicine of the above embodiment of the present invention There is special efficacy to the Bone nonunion complication of fracture surgery, also have preferable curative effect to rheumatism, effusion of knee joint.And in the present invention The medicine stating embodiment also has the further advantage that:Raw material are Chinese herbal medicine, have no toxic side effect;Preparation method is simple, and patient can be certainly Row modulation;Six kinds of medicinal materials are widely distributed, easily purchase, low cost.
The composition principle of the medicine of the above embodiment of the present invention is specific as follows.
The leaf that gagger dissipates is monarch drug in a prescription, cries Drugs of Snake Venom, szechwan sida herb, little red robe, rock leafiness, intermediary magnoliavine herb, Herba Schisandrae intermediae, ventilation again Fragrant, yellow angledtwig magnoliavine root stem and leaf, is the complete stool of the nearly edge fruit of Chinese magnoliavine in the middle of dicotyledon medicine Magnoliacea plant, mainly originates from Yunnan.Effect is:Clearly Thermal detoxification, relaxes the muscles and stimulate the blood circulation, swelling and pain relieving, controls influenza, poisonous snake, lyssodexis, rheumatic numbness, traumatic injury, irregular menstruation, carbuncle swells Sore.Meridian distribution of property and flavor, puckery slight bitter, tremble with fear.
The root skin that gagger dissipates is monarch drug in a prescription, and effect is:Clearing heat and detoxicating, relax the muscles and stimulate the blood circulation, swelling and pain relieving, rheumatic numbness, bruise is damaged Wound, carbuncle sore tumefacting virus.
The leaf of powdered medicine for coaptation is ministerial drug, cries Sambucus thunbergiana again, Sambucus chinensis, capsule, air draft rattan, Sambucus chinensis, big stinkweed, the seedling heart is careless, Hopleaf ampelopsis root-bark.Sweet, slight bitter, puts down, wind-dispelling, dampness removing, relaxing muscles and tendons, promoting blood circulation.Cure mainly:Wind-warm syndrome numbness pain, pain in waist and lower extremities, oedema, jaundice, rubella scabies Itch, erysipelas, sore swells, wind-dispelling, dampness removing, relaxing muscles and tendons, oedema of invigorating blood circulation, traumatic injury, fracture, disease is amassed.
Cuttlebone, makes hence it is evident that promoting bone defect healing to act on for assistant, especially obvious with the effect of old cuttlebone, has Synthetism acts on. antiulcer action;Also there is good friction and suction-operated, not only can destroy the conjunctival epithelium tissue of pathology, The blood of toxin and bacterium may be adsorbed with again and ooze out mucus, but no antibacterial action itself.Its main work in the present invention With being protection skin and promoting main skin absorption.
Paris polyphylla makes for assistant, containing multiple steroid saponins, is two, three, four glucosides of diosgenin and pennogenin, separately contains β-moulting hormone, Daucosterol etc..Nature and flavor:Cold nature, bitter.Indication:Clearing heat and detoxicating, swelling and pain relieving, cool liver is calmed the frightened, and makees In malignant boil swollen carbuncle swells, abscess of throat, venomous snake bite, the pain of injury caused by falling and tumbling, convulsion.Its Main Function in the present invention is heat-clearing solution Poison, swelling and pain relieving, the pain of injury caused by falling and tumbling.
Radix Aconiti Kongboensis make for assistant, also known as monkshood essence, and Main Ingredients and Appearance is aconitine, cures mainly:Anti-inflammatory analgetic, dispelling wind and eliminating dampness, Traumatic injury, treating rheumatic ostealgia.Its Main Function in the present invention is anti-inflammatory analgetic.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail.
Embodiment one
A kind of medicine treated traumatic injury, fracture, including the externally dressing consisting of the following composition:By weight, gagger Scattered leaf 26-30 part, root skin 20-30 part that gagger dissipates, leaf 26-30 part of powdered medicine for coaptation, cuttlebone 5-10 part, Paris polyphylla 3-5 Part, Radix Aconiti Kongboensis 3-5 part.
Embodiment two
A kind of medicine treated traumatic injury, fracture, including the externally dressing consisting of the following composition:By weight, gagger Scattered leaf 26-28 part, root skin 25-30 part that gagger dissipates, leaf 26-30 part of powdered medicine for coaptation, cuttlebone 6-10 part, Paris polyphylla 3-5 Part, Radix Aconiti Kongboensis 3-5 part.
Embodiment three
A kind of medicine treated traumatic injury, fracture, including the externally dressing consisting of the following composition:By weight, gagger Scattered leaf 27-30 part, root skin 20-24 part that gagger dissipates, leaf 26-28 part of powdered medicine for coaptation, cuttlebone 5-7 part, Paris polyphylla 3-5 Part, Radix Aconiti Kongboensis 3-5 part.
Example IV
A kind of medicine treated traumatic injury, fracture, including the externally dressing consisting of the following composition:By weight, gagger Scattered leaf 26-30 part, root skin 20-30 part that gagger dissipates, leaf 29-30 part of powdered medicine for coaptation, cuttlebone 5-10 part, Paris polyphylla 3-4 Part, Radix Aconiti Kongboensis 3-4 part.
The pharmaceutical formulation of above-described embodiment one to four, every kind of medicinal material all can be using any part in the range of number, such as in fact Apply the Ju Ti Pei Fang shown in example five to ten six, as shown in table 1.But protection scope of the present invention is not limited only to joining shown in form Side.
The treatment traumatic injury of table 1 embodiment five to ten six offer, the formula of the medicine of fracture
The treatment traumatic injury of all the above embodiment, the medicine of fracture are formed by six kinds of Chinese medicines, all both can control Treat traumatic injury, fracture can be treated again, and when external application uses, treatment week good to the therapeutic effect of above two disease Phase is short.Clinical tests prove that, using drug therapy treatment traumatic injury and the fracture of the present invention, 3 days left sides of general traumatic injury Can take effect in the right side, be almost recovered within 3-7 days, and fracture is almost recovered for 15 to 25 days.In addition, the medicine of above-described embodiment is to fracture surgery Bone nonunion complication have special efficacy, also have preferable curative effect to rheumatism, effusion of knee joint.And the medicine of above-described embodiment is also Have the further advantage that:Raw material are Chinese herbal medicine, have no toxic side effect;Preparation method is simple, and patient can voluntarily modulate;Six kinds of medicinal materials divide Cloth extensively, is easily purchased, low cost.
The treatment traumatic injury of all the above embodiment, fracture medicine composition principle specific as follows.
The leaf that gagger dissipates is monarch drug in a prescription, cry that Drugs of Snake Venom, gagger be scattered again, szechwan sida herb, little red robe, rock leafiness, Herba Schisandrae intermediae, ventilation Fragrant, yellow angledtwig magnoliavine root stem and leaf, is the complete stool of the nearly edge fruit of Chinese magnoliavine in the middle of dicotyledon medicine Magnoliacea plant, mainly originates from Yunnan.Effect is:Clearly Thermal detoxification, relaxes the muscles and stimulate the blood circulation, swelling and pain relieving, controls influenza, poisonous snake, lyssodexis, rheumatic numbness, traumatic injury, irregular menstruation, carbuncle swells Sore.Meridian distribution of property and flavor, puckery slight bitter, tremble with fear.
The root skin that gagger dissipates is monarch drug in a prescription.Effect is:Clearing heat and detoxicating, relax the muscles and stimulate the blood circulation, swelling and pain relieving, rheumatic numbness, bruise is damaged Wound, carbuncle sore tumefacting virus.
The leaf of powdered medicine for coaptation is ministerial drug, cries Sambucus thunbergiana again, Sambucus chinensis, capsule, air draft rattan, Sambucus chinensis, big stinkweed, the seedling heart is careless, Hopleaf ampelopsis root-bark.Sweet, slight bitter, puts down, wind-dispelling, dampness removing, relaxing muscles and tendons, promoting blood circulation.Cure mainly:Wind-warm syndrome numbness pain, pain in waist and lower extremities, oedema, jaundice, rubella scabies Itch, erysipelas, sore swells, wind-dispelling, dampness removing, relaxing muscles and tendons, oedema of invigorating blood circulation, traumatic injury, fracture, disease is amassed.In addition, the distribution of powdered medicine for coaptation Very wide, easily take.
Cuttlebone is cuttlebone again, makes for assistant, hence it is evident that promoting bone defect healing to act on, especially to act on the most with old cuttlebone Substantially, there is synthetism effect. antiulcer action;Also there is good friction and suction-operated, not only can destroy the conjunctiva of pathology Epithelial tissue, may be adsorbed with the blood of toxin and bacterium again and ooze out mucus, but no antibacterial action itself.It is in the present invention Main Function be protection skin and promote main skin absorption.
Paris polyphylla makes for assistant, containing multiple steroid saponins, is diosgenin(diosgenin)And pennogenin (pennogenin)Two, three, four glucosides, separately contain β-moulting hormone, Daucosterol etc..Nature and flavor:Cold nature, bitter.Function master Control:Clearing heat and detoxicating, swelling and pain relieving, cool liver is calmed the frightened, and makees in swell carbuncle swells, abscess of throat, venomous snake bite, the pain of injury caused by falling and tumbling, infantile convulsion of malignant boil and takes out Jerk.Its Main Function in the present invention is clearing heat and detoxicating, swelling and pain relieving, the pain of injury caused by falling and tumbling.
Radix Aconiti Kongboensis make for assistant, also known as monkshood essence, and Main Ingredients and Appearance is aconitine, cures mainly:Anti-inflammatory analgetic, dispelling wind and eliminating dampness, Traumatic injury, treating rheumatic ostealgia.Its Main Function in the present invention is anti-inflammatory analgetic.
Embodiment 17
The treatment traumatic injury of all the above embodiment, the medicine of fracture all can adopt following preparation method, including following Step:
The first step:According to formula, root skin that the leaf that dissipates gagger respectively, gagger dissipate, the leaf of powdered medicine for coaptation, cuttlebone, Paris polyphylla and Radix Aconiti Kongboensis, grind into powder, remix, obtain raw mixture.
Second step:Raw mixture is made externally dressing.
In actual fabrication process, also can directly purchase the powder agent of six kinds of medicinal materials in formula, the step saving grinding.Separately Outward, it is also possible to first mix six kinds of medicinal materials in the above-mentioned first step, then it is ground.
In above-mentioned second step, the method making externally dressing has many kinds it is preferable that can adopt with the following method:First to flour Middle addition boiling water, is stirred for, obtains efficacy-enhancing ingredient;Again efficacy-enhancing ingredient and raw mixture are mixed, add boiling water, the bruise that obtains medical treatment is damaged Wound, the medicine of fracture.In this method, as efficacy-enhancing ingredient, Main Function is to increase medicine to the batter being formed using after flour and water mixing The cohesive of thing, viscosity, so that external application, safety, easily acquisition again simultaneously.In addition, flour is being formed with boiling water mix and blend Honey can also be added after batter, obtain the more preferable efficacy-enhancing ingredient of effect, the Main Function of honey is to increase the viscosity of medicine, promote Enter the transdermal absorption factor of medicine, honey also has bactericidal action simultaneously, and safe without toxic side effect again.In addition, by efficacy-enhancing ingredient With raw mixture mixing, alcohol can also be added after adding boiling water, medicine can be made evenly, degree of adhesion more preferably, also has Cooling effect.
Embodiment 18
The treatment traumatic injury of all the above embodiment, the medicine of fracture may also be employed following preparation method:
Prepare six kinds of medicinal materials according to formula in advance;Flour adds some boiling water, stirs to the batter of sticky shape;Batter adds honeybee Honey, stirs, and forms efficacy-enhancing ingredient;Efficacy-enhancing ingredient adds states the medicinal material preparing, and stirs when adding boiling water, then natural cooling(About 3 points Clock);After cooling, add alcohol, stir and can form final patent medicine.
Wherein, the addition of flour, boiling water, honey and alcohol can according to actual conditions adjustment it is preferable that by weight, The medicinal material that every 104-120 part prepares, adds 15-20 part flour, about 500 parts altogether of boiling water(It is highly preferred that boiling water adopts altogether 200-300 part), honey about 3-5 part, about 4 parts of alcohol.
In addition, the outer coating method for the treatment of traumatic injury mentioned above, the medicine of fracture has many kinds, according to actual conditions Depending on.For example, put well smooth for structure mulberry paper(Structure mulberry paper has good gas permeability and leak resistance, using this paper medicine Transdermal absorption factor is higher), it is placed on paper with wood chip or blade, then patent medicine is uniformly put on structure mulberry paper, then in structure skin Cotton bar is put on the surrounding of paper, then above every on alcohol gauze can be to employ.And typically apply 3 in site of disease My god(The same day adds medicine to, and pulls down medicine the day after tomorrow)The state of an illness can be clearly better.In addition, the suggestion consumption of the medicine of the present invention is each 110g Left and right, can adjust in therapeutic process as one sees fit.
Clinical example
In order to be illustrated more clearly that the effect of the present invention, clinical example also provided below.
Clinical case:Be related to sprain, get injured by a fall, the disease such as lumbar strain, fracture, protrusion of lumber intervertebral disc, effusion of knee joint, rheumatism Example.
Treatment method:All liniments, and medicine is the preparation of formula according to embodiment 16 and embodiment 18 Method is obtained.
Treatment results are as follows(Often bag medicine hereinafter described weighs about 110g):
Hand(Including shoulder)Sprain 30, be slight soft tissue injury, liniment 1-2 bag, totally 5 days, the having of healing 25, mitigation have 5.
Hand gout and compare swelling(Swelling is serious, as steamed bun)Get injured by a fall 30, liniment 3-4 bag, common 11- 12 days, healing have 20, subsided a swelling go back pain spot have 10.
Lumbar strain, protrusion of lumber intervertebral disc(Leg not type bitterly), acute waist dampens(Walk all very pain that, get up all difficult) 50, liniment 1-2 bag, totally 5 days, cure 40, alleviate 2, invalid 8.
Knee joint, sprain of ankle joint get injured by a fall 60(Ipsilateral swells 1 times than strong side), liniment 5 to 6 bag, common 15-17 days, 50 curing, 6 of rehabilitation 70-80%, 4 of rehabilitation 3-5%.
Effusion of knee joint(Moderate, do not reach or can not smoke how many, or doctor is it is not recommended that smoke)60, external application 4 Wrap 6 bag medicines, common 12-21 days, 51 of healing(Magnetic resonance check can be clapped), 9 of alleviation.
Chest, hip soft tissue damages 30, external application 2-3 bag medicine, totally 7 days, cures 30.
Finger, fracture of metacarpal bone, fracture of calcaneus(Dislocation-free)160, medicine for external application 8 to 10 wrap, common 22-30 days, film making answer Look into recovery from illness 160(Some youths, physique is good, as long as the state of an illness is just fully recovered for light 4 to 6 times common 12-18 days).
Post operation Bone nonunion(I.e. bone does not grow)Half a year to 1 year, 16, external application 12 to 20 bag medicine, totally 46 days -58 My god, 16 of film making growth of spur(Remove the misery of bone grafting of performing the operation once again from), the longest 11 year 3 moonset length, wrap 22 Secondary, poroma length.
The fracture of dislocation and the fracture of privileged sites(Clavicle, fracture of neck of femur)12, first reset, fix 15 days, outer The topical application of drug 6 is wrapped, 2 totally months, cures 12.
The waist of rheumatalgia, membra arthralgia 30(Dysarthrasis and indeformable), external application 4 bag medicine, totally 12 days, cure 20,10 of pain relief.
From the result of above-mentioned clinic example, the medicine of the present invention not only can treat multiple diseases, and curative effect is all very Hurry up, in particular for traumatic injury and fracture.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for the skill of this area For art personnel, the present invention can have various modifications and variations.All within the spirit and principles in the present invention, made any repair Change, equivalent, improvement etc., should be included within the scope of the present invention.

Claims (5)

1. treatment traumatic injury, the medicine of fracture be it is characterised in that by weight, leaf 26-28 part that gagger dissipates, and gagger dissipates Root skin 25-30 part, leaf 26-30 part of powdered medicine for coaptation, cuttlebone 6-10 part, Paris polyphylla 3-5 part, Radix Aconiti Kongboensis 3-5 part.
2. the preparation method of the treatment traumatic injury described in claim 1, the medicine of fracture is it is characterised in that include following step Suddenly:
Step A:According to formula, root skin that the leaf that dissipates described gagger respectively, described gagger dissipate, the leaf of described powdered medicine for coaptation, Described cuttlebone, described Paris polyphylla and described Radix Aconiti Kongboensis, grind into powder, remix, obtain raw mixture;
Step B:Described raw mixture is made externally dressing.
3. treatment traumatic injury according to claim 2, the preparation method of the medicine of fracture are it is characterised in that described step Rapid B further includes:
Step B1:Add boiling water in flour, be stirred for, obtain efficacy-enhancing ingredient;
Step B2:By described efficacy-enhancing ingredient and described raw mixture mixing, add boiling water, the traumatic injury that obtains medical treatment, fracture Medicine.
4. treatment traumatic injury according to claim 3, the preparation method of the medicine of fracture are it is characterised in that described step In rapid B2, also include after adding boiling water:Add alcohol.
5. treatment traumatic injury according to claim 3, the preparation method of the medicine of fracture are it is characterised in that described step In rapid B1, also include after stirring:Add honey.
CN201410125521.XA 2014-03-31 2014-03-31 Medicament for treating traumatic injuries and fracture and preparation method thereof Active CN103860828B (en)

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CN105395787A (en) * 2015-12-09 2016-03-16 刘仕炳 Medicinal liquor
CN111588787A (en) * 2020-06-18 2020-08-28 四川药王坛中草药科技有限公司 Traumatic injury pain relieving composition and preparation method thereof

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* Cited by examiner, † Cited by third party
Title
"海螵蛸对骨愈合相关基因表达的影响";高云等;《中医正骨》;20040731;第16卷(第7期);第1-4页 *

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