CN103857392A - 用于治疗增生性疾病的2-甲酰胺环氨基尿素衍生物与Hsp90抑制剂的组合 - Google Patents

用于治疗增生性疾病的2-甲酰胺环氨基尿素衍生物与Hsp90抑制剂的组合 Download PDF

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CN103857392A
CN103857392A CN201280050535.9A CN201280050535A CN103857392A CN 103857392 A CN103857392 A CN 103857392A CN 201280050535 A CN201280050535 A CN 201280050535A CN 103857392 A CN103857392 A CN 103857392A
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cancer
carcinoma
compound
alkyl
treatment
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English (en)
Chinese (zh)
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X·黄
C·夸德
H-Q·王
C·弗里特什
C·R·施奈尔
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Novartis AG
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Novartis AG
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Priority to CN201610906456.3A priority Critical patent/CN106474127A/zh
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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CN201280050535.9A 2011-10-14 2012-10-11 用于治疗增生性疾病的2-甲酰胺环氨基尿素衍生物与Hsp90抑制剂的组合 Pending CN103857392A (zh)

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CN201610906456.3A CN106474127A (zh) 2011-10-14 2012-10-11 用于治疗增生性疾病的2‑甲酰胺环氨基尿素衍生物与Hsp90抑制剂的组合

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US201161547308P 2011-10-14 2011-10-14
US61/547,308 2011-10-14
PCT/EP2012/070171 WO2013053833A1 (en) 2011-10-14 2012-10-11 2 - carboxamide cycloamino urea derivatives in combination with hsp90 inhibitors for the treatment of proliferative diseases

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CN201610906456.3A Pending CN106474127A (zh) 2011-10-14 2012-10-11 用于治疗增生性疾病的2‑甲酰胺环氨基尿素衍生物与Hsp90抑制剂的组合

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US (2) US20140275089A1 (cg-RX-API-DMAC7.html)
EP (1) EP2766015A1 (cg-RX-API-DMAC7.html)
JP (2) JP6180420B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140078656A (cg-RX-API-DMAC7.html)
CN (2) CN103857392A (cg-RX-API-DMAC7.html)
AU (1) AU2012322976B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014008400A2 (cg-RX-API-DMAC7.html)
CA (1) CA2851383A1 (cg-RX-API-DMAC7.html)
MX (1) MX2014004559A (cg-RX-API-DMAC7.html)
RU (2) RU2017119219A (cg-RX-API-DMAC7.html)
WO (1) WO2013053833A1 (cg-RX-API-DMAC7.html)

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WO2013053833A1 (en) 2013-04-18
KR20140078656A (ko) 2014-06-25
JP2017214387A (ja) 2017-12-07
EP2766015A1 (en) 2014-08-20
RU2017119219A3 (cg-RX-API-DMAC7.html) 2018-11-02
US20160199365A1 (en) 2016-07-14
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