CN103848980A - Special PET (polyester) medical chip and preparation method thereof - Google Patents
Special PET (polyester) medical chip and preparation method thereof Download PDFInfo
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- CN103848980A CN103848980A CN201410070694.6A CN201410070694A CN103848980A CN 103848980 A CN103848980 A CN 103848980A CN 201410070694 A CN201410070694 A CN 201410070694A CN 103848980 A CN103848980 A CN 103848980A
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Abstract
The invention aims at providing a special PET (polyester) medical chip which is good in hydrophobicity, high in transparency, safe to use, radiation-resisting and capable of overcoming the weaknesses of the traditional glass medical product that the weight is heavy, the transportation cost is high, the pipe wall is easy to damage and a sample is easy to leak in the transportation, centrifuging and test process and a preparation method thereof. One ton PET chip is prepared by adopting the following raw materials: 820kg to 850kg of terephthalic acid (PTA), 20kg to 25kg of isophthalic acid (IPA), 320kg to 350kg of ethylene glycol (MEG), 2.2kg to 2.6kg of diethylene glycol (DEG) and 0.025kg to 0.035kg of phosphoric acid. The raw materials are mixed and polymerized through a polyester device to produce a basic PET chip, and then the basic PET chip is crystallized, dehydrated, dust-removed and finally cooled by a solid crystallizer and a preheater to obtain the special PET medical chip. The special PET medical chip can be used for the technical field of the macromolecule material medical product.
Description
Technical field
The present invention relates to special section of a kind of PET medical treatment and preparation method thereof, relate in particular to a kind of special section of PET medical treatment that can be applicable to macromolecular material medical article technical field and preparation method thereof.
Background technology
PET is oyster white highly crystalline polymkeric substance, smooth surface and glossy, not only resistance to creep, antifatigue and wear resistance are better for it, and wear away little, hardness is high, resistance to pressure is strong, has in thermoplastics maximum toughness; Meanwhile, its electrical insulating property is good, and temperature influence is less, nontoxic and chemical proof good stability, weak acid resistant and organic solvent.At present, what be widely known by the people most is, polyethylene terephthalate (PET) is often applied to the manufactures such as cushion, carbonated beverage bottle, edible oil bottle, castor, drug bottle and bottle for cosmetics, but in the PET section field for medical articles such as the special blood sampling test tube of medical treatment and medical laboratory's test tubes, both at home and abroad still in the technological gap stage; Although all started both at home and abroad medical treatment special PET section composition and technique to study, it is still in the laboratory study stage, and complete technical scheme so far there are no.
Aspect the composition and proportioning of PET, the PET(bottle level PET used of tradition bottle blowing) composition and proportioning be to be used for the medical articles such as the special blood sampling test tube of machining medical and medical laboratory's test tube, be mainly reflected in limiting viscosity, fusing point and the degree of crystallinity of PET; The fusing point of general bottle level PET is at 253 ± 1 ℃, degree of crystallinity is 50%～55%, viscosity is within the scope of 0.75～0.88dl/g, above-mentioned characteristic parameter has determined not easy-formation and moulding is slow, the test tube wall defect that is prone to eccentric phenomena in uneven thickness of the parison of the ting model such as blood sampling test tube, medical experimental chamber test tube medical treatment injection moulded products, and the goods scrap rate of final output is high, and then waste production cost, so we need to carry out modification to existing bottle level PET, make it can make quality well and produce the special medical goods that good article rate is high.
Compared with the medical article that adopts PET materials processing to form, not only quality weighs, is not easy to transportation to the glass medical article of prior art, the damaged probability of tube wall is large, and cost is high, radiation hardness not, and carry, occur in centrifugal or process of the test the possibility of leaking at sample very big, therefore PET medical article replaces glass medical article to become at last a kind of trend.
Summary of the invention
Technical problem to be solved by this invention is to overcome the deficiencies in the prior art, aim to provide that a kind of hydrophobicity is good, transparency is high, use safety, radiation hardness, and can overcome that traditional glass medical article quality is heavy, transportation cost is high, in transportation, centrifugal, process of the test, easily there is special section of PET medical treatment of leaking and preparation method thereof in the easy fragmentation of tube wall and sample.
The technical scheme that in the present invention, the special section of a kind of PET medical treatment adopts is: the special section of a kind of PET medical treatment, calculate by 1 ton of PET section of output, and it comprises following raw material:
Terephthalic acid (PTA) 820～850Kg
M-phthalic acid (IPA) 20～25Kg
Ethylene glycol (MEG) 320～350Kg
Glycol ether (DEG) 2.2～2.6Kg
Phosphoric acid 0.025～0.035Kg.
Preferably, the special section of a kind of PET medical treatment, calculates by 1 ton of PET section of output, and it comprises following raw material:
Terephthalic acid (PTA) 830～840Kg
M-phthalic acid (IPA) 21～24Kg
Ethylene glycol (MEG) 330～340Kg
Glycol ether (DEG) 2.3～2.5Kg
Phosphoric acid 0.028～0.032Kg.
Preferred, the special section of a kind of PET medical treatment, calculates by 1 ton of PET section of output, and it comprises following raw material:
Terephthalic acid (PTA) 837Kg
M-phthalic acid (IPA) 23Kg
Ethylene glycol (MEG) 334Kg
Glycol ether (DEG) 2.4Kg
Phosphoric acid 0.03Kg.
The technical scheme that in the present invention, the preparation method of the special section of a kind of PET medical treatment adopts is:
A, routine requirement in mass ratio, terephthalic acid (PTA), m-phthalic acid (IPA), ethylene glycol (MEG), glycol ether (DEG) and phosphoric acid mixed and put into polyester device and carry out successive polymerization after 10～14 hours, then producing basic PET section through pelletizing system;
B, described basic PET section is sent in solid-phase crystallization device, at the temperature of 170 ± 2 ℃, carries out crystallization for the first time, crystallization time 15～25 minutes, and moisture and dust that described basic PET is cut into slices are above removed;
C, deliver in preheater and carry out crystallization for the second time completing described basic PET section after crystallization for the first time, the temperature of crystallization is controlled between 200～220 ℃, crystallization time 2～3 hours;
D, complete the second subcrystalline PET section and belonged to medical PET section, from preheater, take out described medical PET and cut into slices and carry out air cooling, cooling temperature≤60 ℃;
E, the cooling described medical PET section completing is delivered to and in finished product bin, carried out finished product packing by PET delivery system.
Preferably, the polymerization time in step a is 12 hours, and the crystallization time for the first time in step b is 15 minutes, and the crystallization time for the second time in step c is 2 hours.
The invention has the beneficial effects as follows: because the present invention calculates by 1 ton of PET section of output, it comprises terephthalic acid (PTA) 820～850Kg, m-phthalic acid (IPA) 20～25Kg, ethylene glycol (MEG) 320～350Kg, glycol ether (DEG) 2.2～2.6Kg, phosphoric acid 0.025～0.035Kg, and after mixing, above-mentioned raw materials produces basic PET section through polyreaction, again by solid-phase crystallization device and preheater by basic PET section carry out crystallization, dewater, dedusting, cooling making, so the present invention has following several respects a little:
1, with regard to glass medical article of the prior art, adopt that the medical article hydrophobicity made of the present invention is good, transparency is high, use safety, radiation hardness, can effectively overcome that glass medical container quality is heavy, transportation cost is high, the shortcoming of leaking easily occurs in transportation, centrifugal, process of the test the easy fragmentation of tube wall and sample;
2, with regard to the composition and proportioning of bottle level PET of the prior art, m-phthalic acid (IPA) content in the present invention exceeds 5～8 times than m-phthalic acid (IPA) content in traditional bottle level PET, the increase of m-phthalic acid (IPA) is the regularity in order to reduce PET macromolecular alignment, and then the crystal property of reduction section, make degree of crystallinity reach 35%～45%, thereby softening temperature and the fusing point of PET are reduced, its advantage is not only to improve the processing characteristics of injection moulding, as make medical article wall thickness more evenly and avoid the generation of eccentric phenomena, and can reduce processing temperature, save cost, improve the injection-molded finished transparency, in addition, the present invention is lower compared with the viscosity of bottle level PET, can reach 0.61 ± 0.020dl/g, and this measure is convenient to injection moulded products and is formed parison, can meet the manufacture requirement to small-sized medical articles such as test tubes,
3, with regard to preparation technology, because the limiting viscosity of medical PET is compared with bottle level PET difference, therefore the preparation technology of bottle level PET and production line are not suitable for for making medical PET, through the preparation technology to existing bottle level PET and the technological transformation of production line, be embodied in and after solid-phase crystallization device and preheater, added delivery system and cold air system, more be conducive to the limiting viscosity control of medical PET, thereby further guaranteed the good article rate of injection moulded products.
Accompanying drawing explanation
Fig. 1 is preparation technology's schema of the present invention.
Embodiment
Embodiment mono-:
The special section of a kind of PET medical treatment, calculates by 1 ton of PET section of output, and it comprises following raw material:
Terephthalic acid (PTA) 850Kg
M-phthalic acid (IPA) 21Kg
Ethylene glycol (MEG) 323Kg
Glycol ether (DEG) 2.5Kg
Phosphoric acid 0.03Kg.
As shown in Figure 1, preparation method and the flow process of the special section of the medical treatment of PET described in the present embodiment are as follows:
A, by routine requirement in mass ratio, terephthalic acid (PTA), m-phthalic acid (IPA), ethylene glycol (MEG), glycol ether (DEG) and phosphoric acid are all put into preparation container and are mixed, mixed slurry is admitted to and in polyester device, carries out successive polymerization reaction 12 hours, the reaction occurring in polyester device comprises, the first esterification, the second esterification, precondensation and poly-eventually, PET after having gathered eventually produces basic PET section through pelletizing system, and is temporarily put into section storehouse, basis;
B, the basic PET section of being cut into slices in storehouse in described basis are sent in solid-phase crystallization device, carry out crystallization for the first time at the temperature of 170 ± 2 ℃, and moisture and dust that crystallization was cut into slices above to described basic PET after 15 minutes are removed;
C, deliver in preheater and carry out crystallization for the second time completing described basic PET section after crystallization for the first time, the temperature of crystallization is controlled between 200～220 ℃, crystallization time 2 hours;
D, complete the second subcrystalline PET section and belonged to medical PET section, from preheater, take out described medical PET and cut into slices and put into water cooler and carry out air cooling, cooling temperature≤60 ℃;
E, the cooling described medical PET section completing is delivered to and in finished product bin, carried out finished product packing by PET delivery system.
Detected result: (referring to table 1)
(table 1)
Embodiment bis-:
The special section of a kind of PET medical treatment, calculates by 1 ton of PET section of output, and it comprises following raw material:
Terephthalic acid (PTA) 840Kg
M-phthalic acid (IPA) 24Kg
Ethylene glycol (MEG) 332Kg
Glycol ether (DEG) 2.3Kg
Phosphoric acid 0.03Kg.
Preparation method in preparation method and the embodiment mono-of the special section of PET medical treatment in the present embodiment is basically identical, and difference is: crystallization time is 20 minutes for the first time, and crystallization time is 2.5 hours for the second time.
Detected result: (referring to table 2)
(table 2)
Embodiment tri-:
The special section of a kind of PET medical treatment, calculates by 1 ton of PET section of output, and it comprises following raw material:
Terephthalic acid (PTA) 837Kg
M-phthalic acid (IPA) 23Kg
Ethylene glycol (MEG) 334Kg
Glycol ether (DEG) 2.4Kg
Phosphoric acid 0.03Kg.
Preparation method in preparation method and the embodiment mono-of the special section of PET medical treatment in the present embodiment is basically identical, and difference is: crystallization time is 20 minutes for the first time, and crystallization time is 3 hours for the second time.
Detected result: (referring to table 3)
(table 3)
The detected result being obtained from above table and embodiment, composition proportion scope and preparation technology parameter scope given in the claims in the present invention all can reach the quality standard that medical PET product is produced.
The present invention can be applicable to macromolecular material medical article technical field.
Claims (5)
1. the special section of PET medical treatment, is characterized in that: calculate by 1 ton of PET section of output, it comprises following raw material:
Terephthalic acid (PTA) 820～850Kg;
M-phthalic acid (IPA) 20～25Kg;
Ethylene glycol (MEG) 320～350Kg;
Glycol ether (DEG) 2.2～2.6Kg;
Phosphoric acid 0.025～0.035Kg.
2. the special section of a kind of PET medical treatment according to claim 1, is characterized in that: calculate by 1 ton of PET section of output, it comprises following raw material:
Terephthalic acid (PTA) 830～840Kg;
M-phthalic acid (IPA) 21～24Kg;
Ethylene glycol (MEG) 330～340Kg;
Glycol ether (DEG) 2.3～2.5Kg;
Phosphoric acid 0.028～0.032Kg.
3. the special section of a kind of PET medical treatment according to claim 1 and 2, is characterized in that: calculate by 1 ton of PET section of output, it comprises following raw material:
Terephthalic acid (PTA) 837Kg;
M-phthalic acid (IPA) 23Kg;
Ethylene glycol (MEG) 334Kg;
Glycol ether (DEG) 2.4Kg;
Phosphoric acid 0.03Kg.
4. a preparation method for the special section of a kind of PET medical treatment as claimed in claim 1, is characterized in that: the method comprises the following steps:
A. routine requirement in mass ratio, phthalic acid (PTA), m-phthalic acid (IPA), ethylene glycol (MEG), glycol ether (DEG) and phosphoric acid mixed and put into polyester device and carry out successive polymerization reaction after 10～14 hours, then producing basic PET section through pelletizing system;
B. described basic PET section is sent in solid-phase crystallization device, at the temperature of 170 ± 2 ℃, carries out crystallization for the first time, crystallization time 15～25 minutes, and moisture and dust that described basic PET is cut into slices are above removed;
C. deliver in preheater and carry out crystallization for the second time completing described basic PET section after crystallization for the first time, the temperature of crystallization is controlled between 200～220 ℃, crystallization time 2～3 hours;
D. complete second subcrystalline PET section and belonged to medical PET section, from preheater, take out described medical PET and cut into slices and carry out air cooling, cooling temperature≤60 ℃;
E. the cooling described medical PET section completing is delivered to and in finished product bin, carried out finished product packing by PET delivery system.
5. the preparation method of the special section of a kind of PET medical treatment according to claim 4, is characterized in that: the polymerization time in step a is 12 hours, and the crystallization time for the first time in step b is 15 minutes, and the crystallization time for the second time in step c is 2 hours.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104072738A (en) * | 2014-07-16 | 2014-10-01 | 珠海华润包装材料有限公司 | Novel PET (polyethylene terephthalate) chip and preparation method thereof |
| CN105694016A (en) * | 2016-04-23 | 2016-06-22 | 珠海华润包装材料有限公司 | Formula of PET slices for oil bottles |
| CN105694015A (en) * | 2016-04-23 | 2016-06-22 | 珠海华润包装材料有限公司 | Formula of PET slices for water bottle |
| CN105860038A (en) * | 2016-04-23 | 2016-08-17 | 珠海华润包装材料有限公司 | Production technology of novel medical section |
| CN105860042A (en) * | 2016-04-23 | 2016-08-17 | 珠海华润包装材料有限公司 | PET (polyethylene terephthalate) slice formula for heat pot bottle |
| CN110951062A (en) * | 2019-12-13 | 2020-04-03 | 江苏栖云新材料科技有限公司 | Bottle-grade polyester chip for medicine bottle and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101100504A (en) * | 2006-07-07 | 2008-01-09 | 新疆屯河聚酯有限责任公司 | Low pressure resistant polyethylene terephthalate resin and producing method thereof |
| CN102083884A (en) * | 2008-07-02 | 2011-06-01 | 英威达技术有限公司 | Copolyester for shrink film applications |
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2014
- 2014-02-28 CN CN201410070694.6A patent/CN103848980B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101100504A (en) * | 2006-07-07 | 2008-01-09 | 新疆屯河聚酯有限责任公司 | Low pressure resistant polyethylene terephthalate resin and producing method thereof |
| CN102083884A (en) * | 2008-07-02 | 2011-06-01 | 英威达技术有限公司 | Copolyester for shrink film applications |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104072738A (en) * | 2014-07-16 | 2014-10-01 | 珠海华润包装材料有限公司 | Novel PET (polyethylene terephthalate) chip and preparation method thereof |
| CN105694016A (en) * | 2016-04-23 | 2016-06-22 | 珠海华润包装材料有限公司 | Formula of PET slices for oil bottles |
| CN105694015A (en) * | 2016-04-23 | 2016-06-22 | 珠海华润包装材料有限公司 | Formula of PET slices for water bottle |
| CN105860038A (en) * | 2016-04-23 | 2016-08-17 | 珠海华润包装材料有限公司 | Production technology of novel medical section |
| CN105860042A (en) * | 2016-04-23 | 2016-08-17 | 珠海华润包装材料有限公司 | PET (polyethylene terephthalate) slice formula for heat pot bottle |
| CN110951062A (en) * | 2019-12-13 | 2020-04-03 | 江苏栖云新材料科技有限公司 | Bottle-grade polyester chip for medicine bottle and preparation method thereof |
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| CN103848980B (en) | 2016-05-11 |
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Address after: No. 2001, pingwan 3rd road, petrochemical zone, Gaolan Port Economic Zone, Zhuhai City, Guangdong Province Patentee after: Zhuhai Huarun Chemical Materials Technology Co.,Ltd. Address before: Seven North Road 519050 Guangdong city of Zhuhai Province in the northwest side of the Gaolan Port Economic Zone Petrochemical area Patentee before: ZHUHAI HUARUN PACKAGING MATERIALS Co.,Ltd. |