CN103837477A - Imaging polarization detection system - Google Patents
Imaging polarization detection system Download PDFInfo
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- CN103837477A CN103837477A CN201210474029.4A CN201210474029A CN103837477A CN 103837477 A CN103837477 A CN 103837477A CN 201210474029 A CN201210474029 A CN 201210474029A CN 103837477 A CN103837477 A CN 103837477A
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Abstract
The invention discloses an imaging polarization detection system. According to the imaging polarization detection system, a light source halogen lamp is used for emitting visible light; the visible light is delivered through an incident light transmission optical fiber, and condensation is realized using a collecting lens; a 4F collimation system is composed of a first lens, a second lens, and a first optical grating; a polarizer is used for polarizing of the visible light so as to obtain linear polarized light; and a sample to be detected is irradiated by the modulated linear polarized light with an incidence angle alpha. According to a scattered light detecting part, a beam splitting polarization analyzer is used as a polarization analyzer; a part of the backward scattered light which is parallel to the polarizer, and a part of the backward scattered light which is vertical to the polarizer can be selected using the beam splitting polarization analyzer; condensation of the light scatted by the sample 6 is realized using the second lens and a third lens, and the light is delivered through a first optical fiber and a second optical fiber successively, and then is delivered into a multi-channel optical splitter of a spectrograph for detecting; imaging is clear; resolution ratio is high; and imaging is accurate.
Description
Technical field
A kind of imaging Polarization Detection of the present invention system, the invention belongs to the optical polarization system field that medical treatment detects, and is mainly that epithelium stops canceration getting up early diagnostic system that a kind of imaging Polarization Detection system is provided.
Background technology
Life and health is the eternal topics of the mankind, but cancer is as one of main killer of the mankind, the life and health that is still worldwide threatening many people." report of world's cancer " indication of the World Health Organization (WHO), the following several years will be the global cancer patient time occurred frequently, the annual newly-increased cancer patient's number in the whole world will reach 1,500 ten thousand people, die from cancer number more than 600 ten thousand, will increase again 50% to the incidence of global range malignant tumour in 2020.Therefore, the diagnosis of cancer and the topic of having treated into whole mankind's care.Data shows, state of an illness when cancer patient's survival period directly depends on diagnosis, and can fully recover approximately 1/3rd patient of early diagnosis and therapy, and clinical cancer imaging detects the patient who finds and often can not be restored in cancer middle and advanced stage.Therefore, research cancer technique for detection has very important significance.
Whole swollen neoplastic process has been summarized in the variation of cytomorphology, is one of key feature of making a definite diagnosis of tumour, and the formation of tumour is also often reflected in the variation of cellular morphology at first.Pathological research shows to exceed 85% cancer and comes from epithelial tissue, and the early stage most important feature of cancer shows as nucleus size, the karyoplasmic ratio of epithelial layer inner tumour cell, the increase of nuclear chromatin.At present, clinical detection to the early signal of these cancers, have to rely on the biopsy such as pathological section, cell smear means, take off a small pieces tissue from position to be detected, then analyze with microscope.The Random Biopsies of this intrusive mood brings very large misery to patient, and need to spend certain Diagnostic Time, and the subjective factor such as the conclusion drawing and analyst's experience has much relations, and the border in Accurate Determining canceration district is just more difficult.
Summary of the invention
The technical problem to be solved in the present invention is to organize early diagnosis system for carcinogenesis to provide that a kind of imaging clearly, resolution are high, the accurate a kind of imaging Polarization Detection system of imaging.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of imaging Polarization Detection system, comprises that incident light regulates part and scattered light test section,
Incident light adjusting portion is divided and is comprised Halogen lamp LED 1, incident light conduction optical fiber 2, auto-collimating optical system 3, polaroid 4, beam splitter 5;
Scattered light test section comprises the second grating 7, catoptron 8, the 3rd grating 9, beam separation analyzer 10, the 3rd lens 11, the first importing optical fiber 12, the 4th lens 13, the second importing optical fiber 14, multiple tracks spectroscope 15;
The first grating 3.2 is positioned on the focal plane of the second lens 3.3, after polaroid is arranged on the far-end autocollimation system 3 of incident conduction optical fiber 2, the polarizer 4 is in the incident beam modulated part, light beam analyzing separation vessel 10 is at flashlight probe portion, light source Halogen lamp LED 1 wideband light source, multiple tracks spectroscope is arranged on the first importing optical fiber 12, second imports optical fiber 14 ends, become two channels to enter spectroanalysis instrument beam separation, the light that reflective mirror 8 reflects through detecting sample 6 for the isolated light of folded light beam separation vessel 5, the light that beam separation analyzer 10 reflects for departing from catoptron 8, light is imported after lens light gathering to the first importing optical fiber 12, second imports in optical fiber 14, the 3rd lens 11 and the 4th lens 13 are convergent lenses.
Principle of work of the present invention is:
Light source Halogen lamp LED 1, emission wavelength ranges is the visible ray of 400～900nm, derive optical fiber through incident light conduction optical fiber 2, again through condenser optically focused, first lens 3.1, first lens 3.3 and the common composition 4F of the first grating 3.2 colimated light system, wherein the first grating 3.2 is positioned at first lens 3.1, on the focal plane of the second lens 3.3, the aperture of the first grating 3.2, change the degree of collimation of light, the first grating 3.2 is adjusted to hour, obtain the visible ray of collimation, the polarizer 4 is used for visible ray to rise partially, produce linearly polarized photon, the linearly polarized photon modulating incides and detects on sample 6 with incident angle α, in the test section of scattered light, beam separation analyzer 10 serves as the effect of analyzer, can select component parallel with vertical with the polarizer 4 difference in rear orientation light by beam separation analyzer 10, the light of 6 scatterings of sample passes through respectively first optical fiber 12 after being focused on by the second lens 12 and the 3rd lens 14 after testing, the multiple tracks optical splitter 15 of the 2 14 optical fiber lead-in light spectrometer is surveyed.
Advantage of the present invention is: imaging clearly, resolution is high, imaging is accurate.
Accompanying drawing explanation
Accompanying drawing is structure principle chart of the present invention.
Embodiment
Below in conjunction with accompanying drawing, the specific embodiment of the present invention is described:
As shown in drawings, a kind of imaging Polarization Detection system, comprises that incident light regulates part and scattered light test section,
Incident light adjusting portion is divided and is comprised Halogen lamp LED 1, incident light conduction optical fiber 2, auto-collimating optical system 3, polaroid 4, beam splitter 5;
Scattered light test section comprises the second grating 7, catoptron 8, the 3rd grating 9, beam separation analyzer 10, the 3rd lens 11, the first importing optical fiber 12, the 4th lens 13, the second importing optical fiber 14, multiple tracks spectroscope 15;
The first grating 3.2 is positioned at the second lens 3.3(f=50.8mm, D=30mm), L2(f=50.8mm, D=30mm) focal plane on, utilized the focussing property of lens to directional light, shield the scattered light of wide-angle by diaphragm, thereby the light that makes to incide on sample collimates more.
Polaroid makes the optical fiber polarisation from light source after being arranged on the far-end autocollimation system 3 of incident conduction optical fiber 2.Because this experimental system is based on polarization gate technique, therefore the polaroid 4(Chinese light of standing upright, D=25.4mm), the light beam analyzing separation vessel 10(Chinese light of standing upright, D=25.4mm) be the key components that whole Optical System Design is realized, in system, serve as straight line polarizer.The polarizer 4 is in the incident beam modulated part, and effect is that the natural light that light source is sent becomes linearly polarized photon, is therefore called the polarizer; Light beam analyzing separation vessel 10, at flashlight probe portion, is for detecting component parallel with vertical with the polarization direction difference of incident light in rear orientation light, being therefore known as analyzer.Desirable polaroid, only allows the light beam of specific direction to pass through, and this direction is exactly the polarizing axis of this polaroid, and polarization direction is absorbed completely with the vertical light beam of polarizing axis.
Light source Halogen lamp LED 1 wideband light source, consider the high scattering of biological tissue to visible ray, the light source that we select in experiment is that the model that OLYMPU company provides is LG-PS2, the Halogen lamp LED of 12V, 100W, the microscopical illuminator that Ta Shi the said firm produces, it has following two features: a) spectral distribution of light source is similar to nature white light, and wavelength coverage is 400 ~ 900nm; B) even to the illumination of object.The light sending, by by deriving with the supporting LG-SF optical fiber of light source, meets the condenser MX-TILLB matching with it, numerical aperture N.A.=0.6 of this condenser, diameter D=30mm before fibre-optical probe.The light beam that light source LG-PS2 sends is dispersed, and condenser is exactly the degree of divergence that changes light at this Main Function, makes luminous energy more concentrated.
Multiple tracks spectroscope is arranged on the first importing optical fiber 12, the second importing optical fiber 14 ends, becomes two channels to enter spectroanalysis instrument beam separation.
The light that reflective mirror 8 reflects through detecting sample 6 for the isolated light of folded light beam separation vessel 5.
The 3rd lens 11 and the 4th lens 13 are convergent lenses, focal distance f=30.8mm, and it can will converge to detector surface through the light of sample institute scattering.
The above; only the embodiment of the inventive method; not the present invention is imposed any restrictions, the variation of every any simple modification of above embodiment being done according to technical solution of the present invention, structure replaces and all still belonging in the protection domain of the technology of the present invention system.
Claims (2)
1. an imaging Polarization Detection system, comprises that incident light regulates part and scattered light test section, is characterized in that:
Incident light adjusting portion is divided and is comprised Halogen lamp LED (1), incident light conduction optical fiber (2), auto-collimating optical system (3), polaroid (4), beam splitter (5);
Scattered light test section comprises that the second grating (7), catoptron (8), the 3rd grating (9), beam separation analyzer (10), the 3rd lens (11), first import optical fiber (12), the 4th lens (13), second and import optical fiber (14), multiple tracks spectroscope (15);
The first grating (3.2) is positioned on the focal plane of the second lens (3.3), the far-end autocollimation system (3) that polaroid is arranged on incident conduction optical fiber (2) afterwards, the polarizer (4) is in the incident beam modulated part, light beam analyzing separation vessel (10) is at flashlight probe portion, light source Halogen lamp LED (1) wideband light source, multiple tracks spectroscope is arranged on the first importing optical fiber (12), second imports optical fiber (14) end, become two channels to enter spectroanalysis instrument beam separation, the light that reflective mirror (8) reflects through detecting sample (6) for the isolated light of folded light beam separation vessel (5), beam separation analyzer (10) is for departing from the light of catoptron (8) reflection, light is imported after lens light gathering to the first importing optical fiber (12), second imports in optical fiber (14), the 3rd lens (11) and the 4th lens (13) are convergent lenses.
2. a kind of imaging Polarization Detection system according to claim 1, it is characterized in that: light source Halogen lamp LED (1), emission wavelength ranges is the visible ray of 400～900nm, derive optical fiber through incident light conduction optical fiber (2), again through condenser optically focused, first lens (3.1), first lens (3.3) and the first grating (3.2) form 4F colimated light system jointly, wherein the first grating (3.2) is positioned at first lens (3.1), on the focal plane of the second lens (3.3), the aperture of the first grating (3.2), change the degree of collimation of light, the first grating (3.2) is adjusted to hour, obtain the visible ray of collimation, the polarizer (4) is used for visible ray to rise partially, produce linearly polarized photon, the linearly polarized photon modulating incides and detects on sample (6) with incident angle α, in the test section of scattered light, the effect that beam separation analyzer (10) serves as analyzer, can select component parallel with vertical with the polarizer 4 difference in rear orientation light by beam separation analyzer (10), the light of 6 scatterings of sample passes through respectively first optical fiber (12) after being focused on by the second lens (12) and the 3rd lens (14) after testing, the multiple tracks optical splitter (15) of the second (14) optical fiber lead-in light spectrometer is surveyed.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210474029.4A CN103837477A (en) | 2012-11-21 | 2012-11-21 | Imaging polarization detection system |
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| CN201210474029.4A CN103837477A (en) | 2012-11-21 | 2012-11-21 | Imaging polarization detection system |
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| CN103837477A true CN103837477A (en) | 2014-06-04 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106018290A (en) * | 2016-07-04 | 2016-10-12 | 长春理工大学 | Dual-waveband active-polarization target identification system for observing sea fog environment |
| CN106094234A (en) * | 2016-07-26 | 2016-11-09 | 中国科学院西安光学精密机械研究所 | A kind of autocollimatic light path system with polarization beam splitting element |
-
2012
- 2012-11-21 CN CN201210474029.4A patent/CN103837477A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106018290A (en) * | 2016-07-04 | 2016-10-12 | 长春理工大学 | Dual-waveband active-polarization target identification system for observing sea fog environment |
| CN106094234A (en) * | 2016-07-26 | 2016-11-09 | 中国科学院西安光学精密机械研究所 | A kind of autocollimatic light path system with polarization beam splitting element |
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Application publication date: 20140604 |