CN103830500A - Traditional Chinese medicine for treating periodontal diseases caused by kidney-yang deficiency and preparation method thereof - Google Patents
Traditional Chinese medicine for treating periodontal diseases caused by kidney-yang deficiency and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating periodontal diseases caused by kidney-yang deficiency. The traditional Chinese medicine is characterized by being prepared from the following medicines in parts by weight: 9-10 parts of prepared rhizome of rehmannia, 13-15 parts of Chinese yam, 9-10 parts of pulp of dogwood fruit, 5-6 parts of roots of bambooleaf pricklyash root, 9-10 parts of deer-horn glue, 8-9 parts of China dodder, 7-8 parts of cortex eucommiae, 9-10 parts of Chinese angelica, 4-5 parts of cassia bark, 9-10 parts of radix aconiti lateralis preparata, 0-10 parts of oblong leaf garcinia seed oil and 0-8 parts of European verbena herb. A preparation method comprises the steps of weighing and putting the medicines into a container, adding 8 times amount of water, decocting the medicines for 1.5 hours, and filtering the decoction; adding 6 times amount of water to the filter residues, decocting the filter residues for 1 hour, and filtering the decoction; combining the filtrates, concentrating the combined filtrate, drying the concentrate, and filling the product into a capsule shell. Clinical experiments prove that by selecting proper medicines and ratio thereof, the traditional Chinese medicine achieves the obvious effect on treating periodontal diseases caused by kidney-yang deficiency, is safe and does not have toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine of causing because of insufficiency of kidney-YANG periodontal disease and preparation method thereof that is used for the treatment of.
Background technology
Periodontal disease is the chronic destructive disease of the one of periodontal tissue; Refer to gingiva tissue due to for a long time in chronic inflammatory state, the supporting tissues such as periodontal membrane and alveolar bone suffer chronic progressive external destroy a class disease.Primary disease and dental caries are the large tooth reasons of losing of old people two.Clinical manifestation is gingival swelling and pain, hemorrhage, gingiva suppurate or time have odontoseisis, a displacement, meet wind, the stimulation pain such as hot and cold increases the weight of.The cause of disease more complicated of periodontal disease, what think at present periodontal disease is the coefficient result of systemic factor and local factor, most importantly bacterial plaque in its local factor, secondly also have Occlusal Trauma and other local pessimal stimulation, systemic factor includes malnutrition, endocrine and metabolic disturbance and some chronic disease etc.Insufficiency of kidney-YANG: plain body insufficiency of kidney-YANG, or strain is excessively, or cross and take the cold and cool wound that waits the day after tomorrow and cut, causing kidney yang deficiency, life is fiery on the decline.Kidney yang deficiency, is not enough to warm QI and blood, tonneau passages through which vital energy circulates, and warm activating the spleen soil mistake department in addition, biochemical precise and tiny minimizing, fills and moistens fosterly therefore make gum meat dentary lose its temperature, occurs the atrophy of gum meat, and alveolar bone absorbs, periodontal membrane change, tooth root length shakes or dull pain, the diseases such as masticatory atonia.The clinical manifestation that causes periodontal disease because of insufficiency of kidney-YANG is mainly: whole body heating, xerostomia and thirsty, or aversion to wind.Red swelling of gingiva pain, hemorrhage, the many and thickness of the periodontal amount of suppurating, or there is abscess in gingiva many places.Red tip of the tongue, tongue white spirit or BOHUANG, floating and rapid pulse.Still lack at present the effective medicine of generally recognized as safe for the treatment that causes periodontal disease because of insufficiency of kidney-YANG.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine of causing because of insufficiency of kidney-YANG periodontal disease and preparation method thereof that is used for the treatment of, by selecting suitable medical material and proportioning thereof, reach to contribute to treat the remarkable efficacy of periodontal disease, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicine that causes periodontal disease because of insufficiency of kidney-YANG, be prepared from by the medical material of following weight proportion: 9～10 parts, Radix Rehmanniae Preparata, 13～15 parts of Rhizoma Dioscoreaes, 9～10 parts of Fructus Corni, 5～6 parts of Radix Zanthoxyli Planispinis, 9～10 parts of Colla cornus cervis, 8～9 parts of Semen Cuscutae, 7～8 parts of the Cortexs Eucommiae, 9～10 parts of Radix Angelicae Sinensis, 4～5 parts of Cortex Cinnamomis, 9～10 parts of Radix Aconiti Lateralis Preparata, 0～10 part of Olium Garciniae oblongifoliae, 0～8 part of Herba Verbenae.
As preferably, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata.
As preferably, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 8 parts of Herba Verbenae.
As preferably, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae.
As preferably, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae, 8 parts of Herba Verbenae.
A kind of preparation method that causes the Chinese medicine of periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of, comprise the steps: to take Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Radix Zanthoxyli Planispini, Colla cornus cervi, Semen Cuscutae, the Cortex Eucommiae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Olium Garciniae oblongifoliae, Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
As preferably, comprise the steps: to take Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Radix Zanthoxyli Planispini, Colla cornus cervi, Semen Cuscutae, the Cortex Eucommiae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Olium Garciniae oblongifoliae, Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, granulate according to this area common process.
As preferably, comprise the steps: to take Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Radix Zanthoxyli Planispini, Colla cornus cervi, Semen Cuscutae, the Cortex Eucommiae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Olium Garciniae oblongifoliae, Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
The pharmacology analysis of the each Chinese medicinal ingredients of the present invention is as follows:
The Preparation process product of Radix Rehmanniae Preparata [source] Radix Rehmanniae.[nature and flavor] are sweet, tepor.[return through] returns liver, kidney channel.[function cures mainly] nourishing YIN and supplementing blood, beneficial essence is filled out marrow.
The dry rhizome of Rhizoma Dioscoreae [source] Dioscoreaceae plant Rhizoma Dioscoreae.[nature and flavor] are sweet, flat.[return through] returns spleen, lung, kidney channel.[function cures mainly] spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
The drying and ripening sarcocarp of Fructus Corni [source] Cornaceae plant Fructus Corni.[nature and flavor] acid, puckery, tepor.[return through] returns liver, kidney channel.[function cures mainly] liver and kidney tonifying, essence astringing and desertion stemming.
Root bark or the root of Radix Zanthoxyli Planispini [source] rutaceae Fructus Zanthoxyli Plansipini.[nature and flavor] are pungent; Bitter; Temperature; Mild toxicity.[return through] lung meridian.[function cures mainly] expelling wind and cold; Warming middle-JIAO is regulated the flow of vital energy; Promoting blood circulation and stopping pain.
Colla cornus cervi [source] is that Cornu Cervi endures, concentrates through decocting the solid gum of making.[nature and flavor] are sweet, salty, temperature.[return through] returns kidney, Liver Channel.[function cures mainly] temperature compensation Liver and kidney, beneficial intensive culture blood.
The dry mature seed that Semen Cuscutae [source] this product is convolvulus cuscuta plant.[nature and flavor] are sweet, temperature.[return through] returns liver,kidney,spleen warp.[function cures mainly] nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.
The dry bark of the Cortex Eucommiae [source] Eucommiaceae plant Cortex Eucommiae Eucommia ulmoides Oliv..[nature and flavor] are sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
The dry root of Radix Angelicae Sinensis [source] umbelliferae angelica.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
The dry bark of Cortex Cinnamomi [source] canella Cortex Cinnamomi.[nature and flavor] are pungent, sweet, hot greatly.[return through] returns kidney, spleen, the heart, Liver Channel.It is supporing yang that [function cures mainly] mends fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
The processed goods of the daughter root of Radix Aconiti Lateralis Preparata [source] ranunculaceae plant Aconitum carmichjaelii Debx..[nature and flavor] are pungent, sweet, hot greatly; Poisonous.[return through] GUIXIN, kidney, spleen channel.[function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.
The fatty oil of Olium Garciniae oblongifoliae [source] Garcinia maingayii Fructus Garciniae oblongifoliae kernel.[nature and flavor] hardship; Sweet acid; Cool.[function cures mainly] heat-clearing and toxic substances removing; Convergence granulation promoting.
The dry aerial parts of Herba Verbenae [source] Verbenaceae Herba Verbenae.[nature and flavor] hardship, cool.[return through] returns liver, spleen channel.[function cures mainly] promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, removing toxic substances, inducing diuresis to remove edema.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
Through clinical patient's 149 examples that cause periodontal disease because of insufficiency of kidney-YANG of accepting for medical treatment, take the oral agents of making according to embodiment 1, two doses of every days, use continuously 15-20 days.Therapeutic evaluation: cure: transference cure; Effective: symptom alleviates, but do not disappear completely; Invalid: symptom does not disappear, without obviously changing.
Therapeutic outcome: cure and effective totally 128 examples, effective percentage, up to 85.9%, is followed up a case by regular visits to after June again, all without recurrence.
The specific embodiment
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae, 8 parts of Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of and cause periodontal disease because of insufficiency of kidney-YANG.Oral, two doses of every days.
Embodiment 2
Take: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae, 8 parts of Herba Verbenae, insert in container, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Filtering residue adds 2 times of water gagings, decocts 1 hour, filters; Merge three times filtrate, concentrated.
Be used for the treatment of and cause periodontal disease because of insufficiency of kidney-YANG.Oral, two doses of every days.
Embodiment 3
Take: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae, 8 parts of Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of and cause periodontal disease because of insufficiency of kidney-YANG.Oral, two doses of every days.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Everyly belong to apparent variation or the still row in protection scope of the present invention of variation that technical scheme of the present invention extends out.
Claims (8)
1. one kind is used for the treatment of the Chinese medicine that causes periodontal disease because of insufficiency of kidney-YANG, it is characterized in that, be prepared from by the medical material of following weight proportion: 9～10 parts, Radix Rehmanniae Preparata, 13～15 parts of Rhizoma Dioscoreaes, 9～10 parts of Fructus Corni, 5～6 parts of Radix Zanthoxyli Planispinis, 9～10 parts of Colla cornus cervis, 8～9 parts of Semen Cuscutae, 7～8 parts of the Cortexs Eucommiae, 9～10 parts of Radix Angelicae Sinensis, 4～5 parts of Cortex Cinnamomis, 9～10 parts of Radix Aconiti Lateralis Preparata, 0～10 part of Olium Garciniae oblongifoliae, 0～8 part of Herba Verbenae.
2. a kind of Chinese medicine that causes periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata.
3. a kind of Chinese medicine that causes periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 8 parts of Herba Verbenae.
4. a kind of Chinese medicine that causes periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae.
5. a kind of Chinese medicine that causes periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Dioscoreaes, 10 parts of Fructus Corni, 6 parts of Radix Zanthoxyli Planispinis, 10 parts of Colla cornus cervis, 9 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Radix Angelicae Sinensis, 5 parts of Cortex Cinnamomis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Olium Garciniae oblongifoliae, 8 parts of Herba Verbenae.
6. one kind is used for the treatment of the preparation method that causes the Chinese medicine of periodontal disease because of insufficiency of kidney-YANG, it is characterized in that, comprise the steps: to take Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Radix Zanthoxyli Planispini, Colla cornus cervi, Semen Cuscutae, the Cortex Eucommiae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Olium Garciniae oblongifoliae, Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
7. a kind of preparation method that causes the Chinese medicine of periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of according to claim 6, it is characterized in that, comprise the steps: to take Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Radix Zanthoxyli Planispini, Colla cornus cervi, Semen Cuscutae, the Cortex Eucommiae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Olium Garciniae oblongifoliae, Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, granulate according to this area common process.
8. a kind of preparation method that causes the Chinese medicine of periodontal disease because of insufficiency of kidney-YANG that is used for the treatment of according to claim 6, it is characterized in that, comprise the steps: to take Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Radix Zanthoxyli Planispini, Colla cornus cervi, Semen Cuscutae, the Cortex Eucommiae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Olium Garciniae oblongifoliae, Herba Verbenae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
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| CN103356789A (en) * | 2013-07-22 | 2013-10-23 | 兰州理工大学 | Zanthoxylum armatum total alkaloids extract, and preparation method and application thereof |
| CN103599490A (en) * | 2013-11-29 | 2014-02-26 | 成都九芝堂金鼎药业有限公司 | Preparation method of traditional Chinese medicine pill for treating periodontitis |
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- 2014-03-14 CN CN201410094026.7A patent/CN103830500A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1772166A (en) * | 2005-10-27 | 2006-05-17 | 叶明伟 | Chinese herbal medicine decoction for treating kidney-Yang deficiency type senile cataract and its prepn |
| CN102266464A (en) * | 2011-07-11 | 2011-12-07 | 张安美 | Chinese medicinal composition for treating periodontitis |
| CN102697967A (en) * | 2012-06-16 | 2012-10-03 | 李承平 | Tablet for blacking hair, benefiting brains and nourishing liver and kidney |
| CN103356789A (en) * | 2013-07-22 | 2013-10-23 | 兰州理工大学 | Zanthoxylum armatum total alkaloids extract, and preparation method and application thereof |
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Application publication date: 20140604 |