CN103828819B - A kind of bactericidal composition containing prothioconazoles Yu isotianil - Google Patents
A kind of bactericidal composition containing prothioconazoles Yu isotianil Download PDFInfo
- Publication number
- CN103828819B CN103828819B CN201410070444.2A CN201410070444A CN103828819B CN 103828819 B CN103828819 B CN 103828819B CN 201410070444 A CN201410070444 A CN 201410070444A CN 103828819 B CN103828819 B CN 103828819B
- Authority
- CN
- China
- Prior art keywords
- isotianil
- prothioconazoles
- parts
- effective ingredient
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 54
- WLPCAERCXQSYLQ-UHFFFAOYSA-N isotianil Chemical compound ClC1=NSC(C(=O)NC=2C(=CC=CC=2)C#N)=C1Cl WLPCAERCXQSYLQ-UHFFFAOYSA-N 0.000 title claims abstract description 53
- 230000000844 anti-bacterial Effects 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 claims abstract description 20
- 239000004615 ingredient Substances 0.000 claims abstract description 15
- 241000221785 Erysiphales Species 0.000 claims abstract description 14
- 239000000839 emulsion Substances 0.000 claims abstract description 8
- 239000006071 cream Substances 0.000 claims abstract description 6
- 239000003094 microcapsule Substances 0.000 claims abstract description 6
- 239000004563 wettable powder Substances 0.000 claims abstract description 6
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 5
- 239000000375 suspending agent Substances 0.000 claims abstract description 5
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 5
- 239000002552 dosage form Substances 0.000 claims abstract 2
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims description 7
- 230000000361 pesticidal Effects 0.000 claims description 7
- 240000006676 Cucumis sativus var. sativus Species 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 15
- 239000000575 pesticide Substances 0.000 abstract description 14
- 240000007594 Oryza sativa Species 0.000 abstract description 12
- 235000007164 Oryza sativa Nutrition 0.000 abstract description 11
- 235000009566 rice Nutrition 0.000 abstract description 10
- 210000000582 Semen Anatomy 0.000 abstract description 9
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 abstract description 5
- 241001530056 Athelia rolfsii Species 0.000 abstract description 4
- 150000001875 compounds Chemical class 0.000 abstract description 4
- 239000008187 granular material Substances 0.000 abstract description 4
- 240000005979 Hordeum vulgare Species 0.000 abstract description 3
- 235000007340 Hordeum vulgare Nutrition 0.000 abstract description 3
- 239000003814 drug Substances 0.000 description 25
- 239000003795 chemical substances by application Substances 0.000 description 23
- 239000002270 dispersing agent Substances 0.000 description 13
- 241000894006 Bacteria Species 0.000 description 10
- -1 Isothiazole Carbox amide Chemical class 0.000 description 10
- 230000000694 effects Effects 0.000 description 10
- 241000196324 Embryophyta Species 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 238000009114 investigational therapy Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 7
- 231100000419 toxicity Toxicity 0.000 description 7
- 230000001988 toxicity Effects 0.000 description 7
- 231100000820 toxicity test Toxicity 0.000 description 7
- 240000008067 Cucumis sativus Species 0.000 description 6
- 241000209140 Triticum Species 0.000 description 6
- 239000002253 acid Substances 0.000 description 6
- 239000003995 emulsifying agent Substances 0.000 description 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- 230000003902 lesions Effects 0.000 description 6
- 230000000607 poisoning Effects 0.000 description 6
- 231100000572 poisoning Toxicity 0.000 description 6
- 230000002265 prevention Effects 0.000 description 6
- 239000002562 thickening agent Substances 0.000 description 6
- 235000021307 wheat Nutrition 0.000 description 6
- 206010039509 Scab Diseases 0.000 description 5
- 239000000945 filler Substances 0.000 description 5
- 230000001717 pathogenic Effects 0.000 description 5
- 239000012071 phase Substances 0.000 description 5
- 239000003381 stabilizer Substances 0.000 description 5
- 239000000080 wetting agent Substances 0.000 description 5
- 241000233866 Fungi Species 0.000 description 4
- 229940051841 POLYOXYETHYLENE ETHER Drugs 0.000 description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000003899 bactericide agent Substances 0.000 description 4
- 239000006184 cosolvent Substances 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 235000019198 oils Nutrition 0.000 description 4
- 229920000056 polyoxyethylene ether Polymers 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 210000004215 spores Anatomy 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 238000010998 test method Methods 0.000 description 4
- 150000001412 amines Chemical class 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 150000003851 azoles Chemical class 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 3
- 229960000539 carbamide Drugs 0.000 description 3
- 235000013877 carbamide Nutrition 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000001804 emulsifying Effects 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 3
- 210000002383 AT1 Anatomy 0.000 description 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K Aluminium chloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
- 210000000481 Breast Anatomy 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 229920001730 Moisture cure polyurethane Polymers 0.000 description 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M NaHCO3 Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- GHMLBKRAJCXXBS-UHFFFAOYSA-N Resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 2
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- HWKQNAWCHQMZHK-UHFFFAOYSA-N Trolnitrate Chemical group [O-][N+](=O)OCCN(CCO[N+]([O-])=O)CCO[N+]([O-])=O HWKQNAWCHQMZHK-UHFFFAOYSA-N 0.000 description 2
- 229920001807 Urea-formaldehyde Polymers 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 230000002528 anti-freeze Effects 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 239000000440 bentonite Substances 0.000 description 2
- 229910000278 bentonite Inorganic materials 0.000 description 2
- HCWYXKWQOMTBKY-UHFFFAOYSA-N calcium;dodecyl benzenesulfonate Chemical group [Ca].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 HCWYXKWQOMTBKY-UHFFFAOYSA-N 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 229940079593 drugs Drugs 0.000 description 2
- 238000003912 environmental pollution Methods 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N n-butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- 230000000149 penetrating Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000003449 preventive Effects 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- 239000011593 sulfur Substances 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 230000002195 synergetic Effects 0.000 description 2
- YXFVVABEGXRONW-UHFFFAOYSA-N toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2R,3R,4S,5R,6S)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2S,3R,4S,5R,6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2R,3R,4S,5R,6R)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
- BVDRUCCQKHGCRX-UHFFFAOYSA-N 2,3-dihydroxypropyl formate Chemical compound OCC(O)COC=O BVDRUCCQKHGCRX-UHFFFAOYSA-N 0.000 description 1
- GHNRTXCRBJQVGN-UHFFFAOYSA-N 4-dodecan-6-ylbenzenesulfonic acid Chemical compound CCCCCCC(CCCCC)C1=CC=C(S(O)(=O)=O)C=C1 GHNRTXCRBJQVGN-UHFFFAOYSA-N 0.000 description 1
- PZZYQPZGQPZBDN-UHFFFAOYSA-N Aluminium silicate Chemical group O=[Al]O[Si](=O)O[Al]=O PZZYQPZGQPZBDN-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N Ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- 235000005637 Brassica campestris Nutrition 0.000 description 1
- 241001301148 Brassica rapa subsp. oleifera Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 206010008570 Chloasma Diseases 0.000 description 1
- 241000233652 Chytridiomycota Species 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N Diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- 210000001161 Embryo, Mammalian Anatomy 0.000 description 1
- 241000221787 Erysiphe Species 0.000 description 1
- 229920001732 Lignosulfonate Polymers 0.000 description 1
- 210000001834 NPE Anatomy 0.000 description 1
- 210000004681 Ovum Anatomy 0.000 description 1
- 229940088417 PRECIPITATED CALCIUM CARBONATE Drugs 0.000 description 1
- 241001223281 Peronospora Species 0.000 description 1
- 241000233614 Phytophthora Species 0.000 description 1
- 241001503436 Plasmodiophora brassicae Species 0.000 description 1
- 241000233626 Plasmopara Species 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 239000004141 Sodium laurylsulphate Substances 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K Trisodium citrate Chemical group [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 241000317942 Venturia <ichneumonid wasp> Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 230000000845 anti-microbial Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 230000000680 avirulence Effects 0.000 description 1
- 235000012216 bentonite Nutrition 0.000 description 1
- 239000003225 biodiesel Substances 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 229920003064 carboxyethyl cellulose Polymers 0.000 description 1
- 150000007942 carboxylates Chemical class 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000005824 corn Nutrition 0.000 description 1
- 230000001419 dependent Effects 0.000 description 1
- 239000002283 diesel fuel Substances 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005669 field effect Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 125000004836 hexamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000000749 insecticidal Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N iso-propanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 1
- 150000003854 isothiazoles Chemical class 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 210000001699 lower leg Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 230000003641 microbiacidal Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 230000003020 moisturizing Effects 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 244000052769 pathogens Species 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- SRAWNDFHGTVUNZ-UHFFFAOYSA-M sodium;3,6-dibutylnaphthalene-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)C1=CC(CCCC)=CC2=CC(CCCC)=CC=C21 SRAWNDFHGTVUNZ-UHFFFAOYSA-M 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000011778 trisodium citrate Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 230000017613 viral reproduction Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 150000003738 xylenes Chemical group 0.000 description 1
Abstract
A kind of bactericidal composition containing prothioconazoles Yu isotianil, the effective ingredient prothioconazoles of this bactericidal composition compounds with isotianil two yuan, and remaining is auxiliary element.In wherein said composition pesticide, effective ingredient prothioconazoles is 1～50: 50～1 with the mass ratio of isotianil, the mass fraction ratio 1%～80% of effective ingredient prothioconazoles and isotianil in preparation, remaining is for allowing the auxiliary element using and accepting in pesticide, the dosage form of composition pesticide of the present invention is cream, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule, water preparation, it is mainly used in preventing and treating industrial crops such as Semen Tritici aestivi, barley powdery mildew, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose, net blotch, the disease such as moire disease and rice blast.
Description
Technical field
The present invention relates to technical field of pesticide combination, particularly relate to a kind of sterilization containing prothioconazoles Yu isotianil
Compositions.
Background technology
Prothioconazoles is a kind of New-type wide-spectrum triazolinthione series bactericidal agent that Beyer Co., Ltd develops, its chemistry entitled (RS)-
2-(2-(1-chlorine cyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl-1-2-dihydro-3-1,2,4-triazole-3-thioketone, prothioconazoles
Toxicity is low, and without teratogenesis, mutagenesis type, to embryo's avirulence, to human and environment safety.Prothioconazoles is mainly used in preventing and treating Cereal
Numerous diseases such as crop such as Semen Tritici aestivi, Fructus Hordei Vulgaris, Brassica campestris L, Semen arachidis hypogaeae, Oryza sativa L. and legume crop.Almost all wheat and barley diseases are had very well
Prevention effect, such as Semen Tritici aestivi and the powdery mildew of Fructus Hordei Vulgaris, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose, net blotch, moire
Sick etc..Oil Lay and the soil-borne disease of Semen arachidis hypogaeae can also be prevented and treated, such as sclerotiniose, and main foliage disease, as gray mold, melasma,
Brown spot, balck shank, sclerotiniose and rust etc..
Isotianil is that Bayer researches and develops the isothiazole series bactericidal agent for preventing and treating rice blast jointly with Sumitomo Chemical.Isothiazole
Carbox amide includes that isotianil etc. has strong plant induced activity in plant, preventative uses or in morbidity
Early application, multiple biotic factor and abiotic component can activated plant self defensive Resistant reaction i.e. system induction resist
Property, and affect multiple links of pathogen life cycle, so that plant produces wide spectrum to multiple fungus, antibacterial, insecticide and virus
Self-protection effect isotianil also there is strong microbiocidal activity, for directly preventing and treating undesirably microorganism, including under
Fungus in the guiding principle of face: plasmodiophora brassicae, ovum spore fungus, chytrid, Zygomycetes, ascomycetes, Basidiomycetes and deuteromycetes.Such as rotten
Mould genus, Phytophthora, Plasmopara, Peronospora, Erysiphe, Venturia, Caulococcus, nuclear cavity Pseudomonas etc..Isotianil is special
It is not successfully used to prevent and treat corn disease, the most anti-Erysiphe kind, rice blast kind or preventing and treating vinegrowing and fruit
With the disease in vegetable growth.
In the real process of agricultural production, using chemical agent is the means that plant pest is maximally efficient of preventing and treating, but
It is easiest to generate the problem that the generation of disease drug resistance by chemical prevention disease.In the chemical control of bacteriosis,
Have been carried out years of researches both at home and abroad, although some antibacterium medicaments have begun to enter practical stage, but chemistry closes
The medicament become has the shortcomings such as cycle length, cost is high, toxicity is big, environmental pollution is serious, can not meet far away agricultural sustainable development
The requirement of exhibition.And long-term use single pesticidal preparations continuously high dose, easily cause the residual of medicament, environmental pollution with
And the problem such as resistance to Drug resistance fungus development.And by contrast, develop and study compounding and mixture efficient, low toxicity, low-residual and have
Have small investment, the lead time is short and is paid attention to both at home and abroad, and numerous and confused increasing develops dynamics.We are in lab screening and field
On the basis of test, filter out prothioconazoles and compound with isotianil, there is obvious potentiation.And about rosickyite bacterium
Azoles there is no people at present reported with the composition pesticide compounded and the application of isotianil.
Summary of the invention
Based on case above, present invention aim at providing a kind of new and effective composition pesticide, be mainly used in preventing and treating
Industrial crops such as Semen Tritici aestivi, barley powdery mildew, banded sclerotial blight, droop, leaf spot, rust, sclerotiniose, net blotch, moire disease and
The diseases such as rice blast.
Technical scheme of the present invention is realized by following measures:
A kind of bactericidal composition containing prothioconazoles Yu isotianil, the effective ingredient prothioconazoles of this composition pesticide
Compounding with isotianil two yuan, remaining is auxiliary element.Effective ingredient prothioconazoles and different thiophene in wherein said composition pesticide
The mass ratio of bacterium amine is 1～50: 50～1, described composition pesticide of the present invention through toxicity test experimental verification, prothioconazoles with
When the mass ratio of isotianil is 1～10: 10～1, synergistic effect is optimum.
The formulations of pesticide that described composition pesticide of the present invention can be prepared are cream, suspending agent, wettable powder, moisture
Shot agent, aqueous emulsion, microemulsion, granule, microcapsule, water preparation.Wherein effective ingredient prothioconazoles and isotianil are in system
Gross mass in agent accounts for the 1%～80% of the whole quality of the pharmaceutical preparations, and when wherein accounting for 1%～50%, toxicity and residual reach preferable
Balance, cost is relatively low.
The specific embodiments of the formulations of pesticide that composition pesticide of the present invention is configured to is as follows:
Described bactericidal composition is cream preparation, and the mass fraction of component is: prothioconazoles 1～50 parts；Isotianil 1
～50 parts；Conventional emulsifier 10～30 parts；Conventional solvents 20～50 parts；Conventional synergist 1～5 parts.This cream preparation concrete
Production stage is for first adding emulsifying agent, potentiation after being completely dissolved in effective ingredient prothioconazoles and isotianil addition solvent
Agent becomes the oily liquids of transparent and homogeneous, fill after stirring, i.e. can be made into the cream preparation of the present composition.
Described bactericidal composition is suspending agent, and the mass fraction of component is: prothioconazoles 1～50 parts；Isotianil 1～
50 parts；Dispersant 5～20 parts；Antifreezing agent 1～5 parts；Thickening agent 0.1～2 parts；Defoamer 0.1～0.8 part；Penetrating agent 0～10
Part；PH value regulator 0.1～5 parts；Water, surplus.The concrete production stage of this suspending agent is for first to mix other auxiliary agents, through at a high speed
Shear-mixed is uniform, adds effective ingredient prothioconazoles and isotianil, abrading-ball 2～3 hours in ball crusher, makes a diameter equal
At below 5mm, i.e. can be made into the aqueous suspension formulations of the present composition.
Described bactericidal composition is wettable powder, and the mass fraction of component is: prothioconazoles 1～50 parts；Different thiophene bacterium
Amine 1～50 parts；Dispersant 3～10 parts；Wetting agent 1～5 parts；Filler, surplus.The concrete production stage of this wettable powder is:
By above-mentioned formula, effective ingredient prothioconazoles is mixed with isotianil and dispersant, wetting agent and filler, in stirred tank
Uniform stirring, at mix homogeneously after jet mill, i.e. can be made into the wettable powder of the present composition.
Described bactericidal composition is water dispersible granules, and the mass fraction of component is: prothioconazoles 1～50 parts；Different thiophene bacterium
Amine 1～50 parts；Dispersant 3～10 parts；Wetting agent 1～10 parts；Disintegrating agent 1～5 parts；Filler, surplus.This water dispersible granules
Concrete production stage is: by above-mentioned formula by effective ingredient prothioconazoles and isotianil and dispersant, wetting agent, disintegrating agent with
And filler mix homogeneously, pulverize with micro jet, through mediating, be subsequently adding in fluidized-bed granulation dryer and make
Grain, be dried, screening after through sample analysis, i.e. can be made into the water dispersible granules of the present composition.
Described bactericidal composition is aqueous emulsion, and the mass fraction of component is: prothioconazoles 1～50 parts；Isotianil 1～
50 parts；Emulsifying agent 3～30 parts；Solvent 5～15 parts；Stabilizer 2～15 parts；Antifreezing agent 1～5 parts；Defoamer 0.1～8 parts；Thickening
Agent 0.2～2 parts；Water, surplus.The concrete production stage of this aqueous emulsion is: first by prothioconazoles and isotianil, solvent and breast
Agent, cosolvent are added together, and make to be dissolved into uniform oil phase；By part water, antifreeze, other the pesticide such as antimicrobial
Auxiliary agent mixes uniformly aqueous phase；While high-speed stirred, oil phase is added aqueous phase in a kettle., slowly add water straight
To reaching phase inversion point, open cutter and carry out high speed shear, and add remaining water, shear about half an hour, form oil-in-water type
Aqueous emulsion, i.e. can be made into the aqueous emulsion of the present composition.
Described bactericidal composition is microemulsion, and the mass fraction of component is: prothioconazoles 1～50 parts, isotianil 1～
50 parts, emulsifying agent 10～30 parts, antifreezing agent 1～8 parts, stabilizer 0.5～10 parts, Conventional solvents cosolvent 20～50 parts.By third
Sulfur bacterium azoles is completely dissolved with isotianil cosolvent, adds other compositions such as emulsifying agent, antifreezing agent stabilizer, uniformly mixes
Close, be eventually adding water, microemulsion after being sufficiently stirred for, can be made into.
Described bactericidal composition is granule, and the mass fraction of component is: prothioconazoles 1～50 parts, isotianil 1～
50 parts, wetting dispersing agent 1～10 parts；Thickening agent 0.1～5 parts；Defoamer 0.1～5 parts；Oleum Ricini, surplus is supplied.To effectively become
Each components such as point prothioconazoles and isotianil, dispersant, stabilizer, defoamer and solvent are mixed in the ratio of formula, put into
After grinding in sand milling still, in sending into mixer for well-distribution, mixing gets product.
Described bactericidal composition is microcapsule, and the mass fraction of component is: prothioconazoles 1～50 parts, isotianil 1
～50 parts, carbamide 5～20 parts；Formaldehyde 5～20 parts；Emulsifying dispersant 5～20 parts；Antifreezing agent 1～5 parts；Thickening agent 0.1～2 parts；
Defoamer 0.1～0.8 part；Water, surplus.Carbamide and formaldehyde (the amount ratio of material is added in equipped with the there-necked flask of agitating device
It is about l:1.5～2.0), with the pH value of sodium hydroxide solution regulation solution to 8～about 9, then heat to 70～80 DEG C, instead
Stable urea resin prepolymer should be obtained.Take a certain amount of prothioconazoles to be dissolved in hexamethylene with isotianil, and at solution
Middle addition emulsifying dispersant, with being stirred vigorously, the stable breast of the O/W type with the aqueous solution containing emulsifying dispersant as aqueous phase that is made into
Liquid.Above-mentioned urea resin prepolymer is added in emulsion, regulate pH value, polyreaction occurs under acid catalysed conditions, makes oil
Phase material is wrapped, and forms microcapsule granule.Slowly heat up, solidification, temperature controls at 40～50 DEG C, hardening time 1h.
Select to add appropriate auxiliary agent, stable microcapsule.
Described bactericidal composition is water preparation, and the mass fraction of component is: prothioconazoles 1～50 parts, isotianil 1～50
Part, wetting dispersing agent 0.1～30 parts；Antifreezing agent 2～8 parts；Defoamer 0.1～1 part；Thickening agent 0.1～3 parts；Spreader-sticker 5～15
Part；Water, surplus is supplied.By effective ingredient prothioconazoles and isotianil, it is completely dissolved with cosolvent, adds dispersant, anti-
Freeze other compositions such as agent, defoamer, uniformly mix, be eventually adding water, after being sufficiently stirred for, finished product.
The most above-described emulsifying agent is selected from calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkyl phenol polyoxy
Vinyl Ether sulfosuccinate, styrylphenol polyoxyethylene ether, NPE, castor oil polyoxyethylene ether,
Aliphatic acid polyethenoxy base ester, any one of polyoxyethylene aliphatic alcohol ether or more than one any mixture than composition.
Described solvent is dimethylbenzene or biodiesel, toluene, diesel oil, methanol, ethanol, n-butyl alcohol, isopropanol, rosin-based
Vegetable oil code name is ND-45, solvent naphtha, dimethylformamide, dimethyl sulfoxide, one or more in water equal solvent
Arbitrarily than the mixture of composition.
Described dispersant is LG-3, GY-D1252, GY-D1256, SNWGF-01 selected from polycarboxylate code name, lignin
Sulfonate code name is 201107,201108, alkylphenol polyoxyethylene methyl ether condensate sulfate, alkylsulfonate calcium salt, naphthalene
Sulfonic formaldehyde condensation compound sodium salt, alkylphenol polyoxyethylene, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, glyceride
One or more in fat acid ester polyoxyethylene ether.
Described wetting agent is selected from sodium lauryl sulphate, calcium dodecyl benzene sulfonate, Nekal BX, moistens penetrating agent F,
Alkylbenzenesulfonate polyoxyethylene triphen phosphenylic acid salt dimly, spaonin powder, Bombyx mori L., one or more in Fructus Sapindi Mukouossi powder.
Described disintegrating agent is selected from bentonite, and carbamide, ammonium sulfate, aluminum chloride, citric acid, succinic acid, in sodium bicarbonate
One or more.
Described thickening agent be selected from xanthan gum, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, Magnesiumaluminumsilicate,
In polyvinyl alcohol one or more.
Described stabilizer is selected from sodium citrate, the one in resorcinol.
Described antifreezing agent is selected from ethylene glycol, propylene glycol, one or more in glycerol.
Described defoamer is selected from silicone oil, silicone compound, C10-20Saturated fat acid compounds, C8-10Fatty alcohol
One or more.
Described filler is selected from Kaolin, and kieselguhr, bentonite, attapulgite, white carbon, starch, in precipitated calcium carbonate
One or more.
The present invention has obvious potentiation with prothioconazoles and the isotianil composite bactericide as effective ingredient, prolongs
The slow drug-fast generation in key, and reduce into product cost and use cost.It is mainly used in preventing and treating powdery mildew, banded sclerotial blight, withering
The diseases such as disease, leaf spot, rust, sclerotiniose, net blotch, moire disease and rice blast.
Detailed description of the invention
For making technical scheme, purpose and advantage are clearer, present invention specific examples below
Illustrate, but the present invention is not limited to these examples.The effect experimental of the present invention uses indoor biometrics and field test phase
In conjunction with mode, if no special instructions, ratio mentioned below is all mass fraction ratio.
Embodiment: prothioconazoles is tested with isotianil different ratio co-toxicity.
1.1 reagent agent
The 95% former medicine of prothioconazoles, the 95% former medicine of isotianil, above-mentioned former medicine is ground by sea rel Pharmaceutical limited company
The portion of sending out provides.
1.2 test targets
Never executed the prothioconazoles Fructus Cucumidis sativi with isotianil and with type to gather potted plantly separate from Shouguang, Shandong, supplied
Examination cucumber variety: Chang Chun Mi Ci.
1.3 test method
1.3.1 medicament preparation
First with the former medicine of acetone solution, according to the result of preliminary experiment, two appropriate former medicines are made into several different ratio,
With acetone, each process is diluted to several Concentraton gradient respectively more stand-by.
Being cultivated in pot for growing seedlings by susceptible cucumber variety Chang Chun Mi Ci, be placed in greenhouse cultivation, plant grows to three to four leaves
After date, gathers the blade of identical leaf age, for cultivation and the mensuration of powdery mildew of cucumber pathogenic bacteria.
1.3.2 the cultivation of powdery mildew of cucumber pathogenic bacteria and the preparation of spore suspension
Powdery mildew of cucumber pathogenic bacteria use plants method 20 DEG C, cultivate under conditions of 12h alternation of light and darkness, every 30 d turn generation
Cultivate 1 time.With the conidium on sterilized water eluting incidence of leaf during inoculation, being configured to spore concentration is l × 106Individual/mL
Suspension.
1.3.3 strains tested sensitivity testing
Leaf dish moisturizing method is used to carry out toxicity test.First the blade of collection is prepared as the leaf dish of a diameter of 1.5cm, at random
Mixing, is respectively placed in the series concentration medicinal liquid configured immersion lh, 50 leaf dishes of each concentration, and test is with not adding medicine
Being processed as blank, soak after terminating, leaf faces up in the absorbent paper being placed in identical liquor strength moistening, leaf dish
On medicinal liquid blot, the spore suspension l0L prepared is inoculated in leaf dish central authorities, after room temperature places 5 min, be placed in 20 DEG C, 1
Cultivate under conditions of 2h alternation of light and darkness, measure the onset area on leaf dish after 10d, calculate EC50。
The percentage rate accounting for leaf disc area according to lesion area divides sick level
0 grade: anosis；
1 grade: sorus area accounts for less than the 5% of whole leaf area；
3 grades: sorus area accounts for below the 6%-10% of whole leaf area；
5 grades: sorus area accounts for below the 11%-20% of whole leaf area；
7 grades: sorus area accounts for below the 21%-50% of whole leaf area；
9 grades: sorus area accounts for more than the 50% of whole leaf area；
1.3.4 mixture toxicity test and interpretation of result
Carry out the toxicity test of mixture according to mixed ratio by single dose toxicity test method.
If comparison mortality rate < 5%, do not correct, comparison mortality rate, between 5%-20%, is corrected by formula 2, and comparison is dead
Die rate 20%, test need to be reformed.
It is independent variable x with the logarithm value of drug concentration (mg/L), with the probability value of corrected mortality for dependent variable y, respectively
Set up virulence regression equation formula, use DPS computed in software single dose and the EC of each proportioning mixture50Poison altogether is calculated according to the abundant method of Sun Yun
Coefficient (CTC).Co-toxicity coefficient CTC, computing formula is as follows: (with prothioconazoles as standard agent, its toxicity index is 100):
The EC of toxicity index (the TI)=prothioconazoles of isotianil50The EC of/isotianil50×100
The EC of true toxicity index (the ATI)=prothioconazoles of M50The EC of/M50×100
TI × P isotianil of the TI × P prothioconazoles+isotianil of theoretical toxicity index (the TTI)=prothioconazoles of M
TTI × 100 of the ATI/M of co-toxicity coefficient (the CTC)=M of M
In formula:
M is the mixture of prothioconazoles and isotianil different ratio
P prothioconazoles is the ratio that prothioconazoles is shared in mixture
P isotianil is the ratio that isotianil is shared in mixture.
2.1 toxicity test results
Table 1 prothioconazoles and the isotianil toxicity test to powdery mildew of cucumber
As can be seen from the table, the result of the test of different proportion proportioning shows, dilutes equal table respectively in effective ingredient ratio
Reveal stronger potentiation, wherein with prothioconazoles: isotianil as 1:10～when 10:1 synergistic effect optimal, it is proposed that
Suitable proportion about 1:10～10:1 mixture preparation is carried out further field control effectiveness test, to evaluate the actual application in its field
Effect.
3, field test preventing and treating wheat powdery mildew, the experimental result of rice blast
3.1 field test preventing and treating wheat powdery mildews
3.1.1 test method
Test site, in great Tong Qiao village, capital town, Fengyang County, is Semen Tritici aestivi for studying thing, and kind is short morning 781, broadcasts sowing, growing way
Preferably, test sets every mu and sets comparison totally 10 process.Often processing and be repeated 4 times, random district group arranges, plot area 30 square metres.
3.1.2 control time and number of times
Before dispenser, after the 1st medicine after 7 days and the 2nd dispenser 7 days, 14 days, every community used diagonal 5 sampling, often
Point investigation 20 strains, before blooming, every strain takes 2 leaves from upper end, and the every strain of Post flowering takes sword-like leave 2 leaf, investigates occurring degree by leaf classification,
Calculate disease to refer to and prevention effect.
Grade scale is as follows:
0 grade: anosis；
1 grade: lesion area accounts for less than the 5% of one-piece blade area；
3 grades: lesion area accounts for the 6%-15% of one-piece blade area；
5 grades: lesion area accounts for the 16%-25% of one-piece blade area；
7 grades: lesion area accounts for the 26%-50% of one-piece blade area；
9 grades: lesion area accounts for more than the 50% of one-piece blade area.
3.1.3 drug effect computational methods
Sick leaf rate (%)=sick number of sheets/investigate the total number of sheets × 100
Disease index=∑ (the sick number of sheets × relative level numerical value at different levels)/(investigating the total number of sheets × 9) × 100
Prevention effect (%)=(disease index after disease index × treatment region medicine before 1-(blank district medicine)/(blank
Disease index before disease index × treatment region medicine after district's medicine)) × 100.
3.1.4 poisoning investigation method
After dispenser, whether continuous 14d range estimation medicament has poisoning to crop.
3.1.5 result of the test and analysis
Each effect processing preventing and treating wheat powdery mildew.
Prothioconazoles and isotianil composite bactericide control effect apparently higher than third for wheat powdery mildew as shown in Table 2
Sulfur bacterium azoles and isotianil single dose, bactericidal effect is incremented by with the increase of dosage.Estimate according to field, in test dose scope
In, plant growth is normal, and the poisoning phenomenon to Semen Tritici aestivi does not all occur in each treatment agent, illustrates that it is safe to Semen Tritici aestivi.Suggestion
The antibacterial different from the mechanism of action is used in mixed way to delay the drug-fast generation of pathogenic bacteria.
3.2 field test preventing and treating rice blast
3.2.1 test method
Test is at Xianning City's paddy base, and test kind is hybrid rice variety, often processes 4 times and repeats, every community
Double diagonal line 5 points of investigation, five strain whole blade during investigation, a situation arises for statistics disease.
Recording occurring degree by staging, grade scale is as follows:
0 grade: anosis；
1 grade: scab heap area accounts for less than the 5% of whole leaf area；
3 grades: scab heap area accounts for below the 6%-10% of whole leaf area；
5 grades: scab heap area accounts for below the 11%-20% of whole leaf area；
7 grades: scab heap area accounts for below the 21%-50% of whole leaf area；
9 grades: scab heap area accounts for more than the 50% of whole leaf area.
3.2.2 control time and number of times
Test investigation 4 times altogether, before medicine, radix investigation, investigates after 7 days, 7 days for the second time and medicine after medicine for the first time for 15 days.
3.2.3 drug effect computational methods
Sick leaf rate (%)=sick number of sheets/investigate the total number of sheets × 100
Disease index=∑ (the sick number of sheets × relative level numerical value at different levels)/(investigating the total number of sheets × 9) × 100
Prevention effect (%)=(disease index after disease index × treatment region medicine before 1-(blank district medicine)/(blank
Disease index before disease index × treatment region medicine after district's medicine)) × 100.
3.2.4 poisoning investigation method
After dispenser, whether continuous 15d range estimation medicament has poisoning to crop.
3.2.5 result of the test and analysis
Rice blast is prevented and treated measurement result by table 3 different disposal
Being shown by above field experiment, prothioconazoles and isotianil complex preparation are bright for the preventive effect of rice blast
Showing and be better than single dose, bactericidal effect is incremented by with the increase of dosage.Estimate according to field, in the range of test dose, plant growth
Normally, occur without poisoning situation, significant for agricultural produce, it is worthy to be popularized.
In sum, the present invention contains the bactericidal composition of prothioconazoles and isotianil, to wheat powdery mildew, Oryza sativa L. rice
Pestilence has good prevention effect, and it is to Target crops safety.Complex preparation not only increases preventive effect, and expand right
The preventing and treating of antibacterial, so this compounded combination has being of great significance in production practices.
Claims (4)
1. contain bactericidal composition application in preparation prevents and treats the pesticidal preparations of powdery mildew of cucumber of prothioconazoles and isotianil,
It is characterized in that: the effective ingredient of this bactericidal composition is prothioconazoles and isotianil binary built, and remaining is auxiliary element,
Wherein effective ingredient prothioconazoles is 3:1 with the mass ratio of isotianil.
Application the most according to claim 1, it is characterised in that: prothioconazoles and the isotianil total matter in pesticidal preparations
Amount accounts for the 1%～80% of whole pesticidal preparations quality.
Application the most according to claim 2, it is characterised in that: prothioconazoles and the isotianil total matter in pesticidal preparations
Amount accounts for the 1%～50% of whole pesticidal preparations quality.
4. according to the application described in claim 1 or 2 or 3, it is characterised in that: the dosage form of this pesticidal preparations be cream, suspending agent,
Wettable powder, water dispersible granules, aqueous emulsion, microemulsion, microcapsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410070444.2A CN103828819B (en) | 2014-02-28 | A kind of bactericidal composition containing prothioconazoles Yu isotianil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410070444.2A CN103828819B (en) | 2014-02-28 | A kind of bactericidal composition containing prothioconazoles Yu isotianil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103828819A CN103828819A (en) | 2014-06-04 |
| CN103828819B true CN103828819B (en) | 2016-11-30 |
Family
ID=
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1826053A (en) * | 2003-07-23 | 2006-08-30 | 拜尔农作物科学股份公司 | Fungicidal active substance combinations |
| CN103025160A (en) * | 2010-07-28 | 2013-04-03 | 日本农药株式会社 | Sigatoka disease control method |
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8426372B2 (en) * | 2003-07-20 | 2013-04-23 | Bayer Cropscience Ag | Fungicidally active compound combinations |
| CN1826053A (en) * | 2003-07-23 | 2006-08-30 | 拜尔农作物科学股份公司 | Fungicidal active substance combinations |
| CN103025160A (en) * | 2010-07-28 | 2013-04-03 | 日本农药株式会社 | Sigatoka disease control method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103355333A (en) | Sterilization composition containing pyraclostrobin and boscalid | |
| CN105409990A (en) | Sterilization composition containing pyraclostrobin and efficient metalaxyl-M | |
| CN105409963A (en) | Sterilization composition containing efficient metalaxyl-M and azoxystrobin | |
| CN103975932B (en) | A kind of bactericidal composition containing prothioconazoles and flumorph | |
| CN103355308A (en) | Sterilization composition containing prothioconazole and boscalid | |
| CN103719102A (en) | Sterilization composite containing fluopyram and prothioconazole | |
| CN103931623A (en) | Bactericidal composition containing meptyldinocap and prothioconazole | |
| CN103828819B (en) | A kind of bactericidal composition containing prothioconazoles Yu isotianil | |
| CN103503879A (en) | Sterilization composition containing prothioconazole and bupirimate | |
| CN103688965A (en) | Bactericidal composition containing fluopyram and pyraclostrobin | |
| CN104054708A (en) | Bactericidal composition containing meptyldinocap and spiroxamine | |
| CN103975928A (en) | Bactericidal composition containing meptyldinocap and penconazole | |
| CN103783046A (en) | Fungicidal composition containing prothioconazole and pyrimethanil | |
| CN102960349A (en) | Germicide composition containing pyraoxystrobin and tiadinil | |
| CN107787990A (en) | A kind of bactericidal composition containing fluorine ether bacterium acid amides and flumorph | |
| CN105394048A (en) | Bactericidal composition containing prothioconazole and efficient metalaxyl-M | |
| CN107361074A (en) | A kind of bactericidal composition containing pyraclostrobin Yu the gloomy copper of thiophene | |
| CN104757005A (en) | Fungicide composition containing metalaxyl and thifluzamide | |
| CN105076166A (en) | Bactericidal composition containing tetramycin and thifluzamide | |
| CN103931624A (en) | Fungicidal composition containing prothioconazole and cyazofamid | |
| CN103814904A (en) | Bactericidal composition containing prothioconazole and cyflufenamid | |
| CN103503881A (en) | Sterilization composition containing prothioconazole and famoxadone | |
| CN103719094B (en) | A kind of bactericidal composition containing pyraoxystrobin Yu ferimzone | |
| CN103798244A (en) | Bactericidal composition containing cyflufenamid and flutriafol | |
| CN103947651A (en) | Fungicidal composition containing (2,4-dinitro-6-(1-methylheptyl)phenylcrotonate,2,4-DNOPC) and difenoconazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant |