CN103816463A - Traditional Chinese medicinal composition for treating chronic colitis - Google Patents
Traditional Chinese medicinal composition for treating chronic colitis Download PDFInfo
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- CN103816463A CN103816463A CN201410062305.5A CN201410062305A CN103816463A CN 103816463 A CN103816463 A CN 103816463A CN 201410062305 A CN201410062305 A CN 201410062305A CN 103816463 A CN103816463 A CN 103816463A
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating chronic colitis. The traditional Chinese medicinal composition is prepared from the following Chinese herbal raw materials, by weight, 10-20 parts of radix saposhnikoviae, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of white peony root, 10-20 parts of dried orange peel, 10-30 parts of Radix Codonopsis, 10-30 parts of Poria cocos, 20-40 parts of coix seeds, 5-15 parts of mutmeg, 10-20 parts of Psoralea corylifolia, 10-20 parts of sharpleaf galangal fruit, 5-15 parts of Terminalia, 5-15 parts of banksia rose, 5-15 parts of Villous Amomum Fruit, 10-30 parts of Chinese yam, 5-15 parts of combined spicebush and 5-20 parts of licorice. The traditional Chinese medicinal formula has appropriate compatibility of medicines. The traditional Chinese medicinal composition for treating chronic colitis has advantages of low manufacturing cost, less cost, simple technology and obvious curative effect, has effects of invigorating spleen, disinhibiting dampness, supplementing the center and boosting qi, warming the kidney and astringe intestine to stop diarrhea and regulating qi-flowing for activating stagnancy, and especially has an effect of treating chronic colitis without relapse based on the theory of supporting the healthy energy and treating both symptoms and root causes.
Description
Technical field
The present invention relates to technical field of Chinese medicines, contain medicinal preparation deriving from Chinese herbal medicine and preparation method thereof, particularly a kind of Chinese medicine composition for the treatment of chronic colitis.
Background technology
Chronic colitis belongs to doctor trained in Western medicine name of disease, is one of clinical common intestinal tract disease, and the cause of disease is still not very clear, thinks at present due to due to environmental factors, inherited genetic factors, infective agent and immune factor etc. interact.Clinically show as that times of defecation increases, five indigested foods, or diarrhoea alternately occurs with constipation, often with borborygmus, abdominal part paroxysmal pain, recurrence, causes deficiency of spleen-YANG and kidneyYANG repeatedly, lazy the saying that occur breathing hard, aversion to cold and cold limbs, lassitude, diarrhea with loose stool or Diarrhoea more.Primary disease is more common in 20-40 year, and sickness rate is higher, has a strong impact on people's normal work and life.Treatment aspect, doctor trained in Western medicine adopts the Therapeutic Method such as aminosallcylic acid preparation and immunosuppressant, glucocorticoid or operation more, and not only treatment cycle is long, and expense is high, and side effect is large, easily outbreak repeatedly, effect is undesirable.
Summary of the invention
The object of this invention is to provide a kind of therapeutic effect obvious, cure rate is high, the Chinese medicine composition of the treatment chronic colitis that relapse rate is low, have no side effect.
For achieving the above object, the invention provides a kind of Chinese medicine composition for the treatment of chronic colitis, made by the raw material of Chinese medicine of following ratio of weight and number: Radix Saposhnikoviae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Paeoniae Alba 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Radix Codonopsis 10-30 part, Poria 10-30 part, Semen Coicis 20-40 part, Semen Myristicae 5-15 part, Fructus Psoraleae 10-20 part, Fructus Alpiniae Oxyphyllae 10-20 part, Fructus Chebulae 5-15 part, Radix Aucklandiae 5-15 part, Fructus Amomi 5-15 part, Rhizoma Dioscoreae 10-30 part, Radix Linderae 5-15 part, Radix Glycyrrhizae 5-20 part.
The present invention treats the Chinese medicine composition of chronic colitis, and the optimum weight portion rate of various raw materials is: Radix Saposhnikoviae 10-15 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Radix Paeoniae Alba 10-15 part, Pericarpium Citri Reticulatae 10-15 part, Radix Codonopsis 15-30 part, Poria 10-20 part, Semen Coicis 25-35 part, Semen Myristicae 8-12 part, Fructus Psoraleae 10-15 part, Fructus Alpiniae Oxyphyllae 15-20 part, Fructus Chebulae 8-12 part, Radix Aucklandiae 8-12 part, Fructus Amomi 10-15 part, Rhizoma Dioscoreae 15-20 part, Radix Linderae 8-12 part, Radix Glycyrrhizae 10-15 part.
Chinese medicine composition of the present invention is according to Chinese medical discrimination theory, and the sick position of primary disease is at large intestine, how relevant with spleen kidney, insufficiency of the spleen heresy is taken advantage of, transportation capabilities obstacle, it is not normal that small intestinal is conducted by Sheng and large intestine, is impairment of the kidney for a long time and rush down, the decline of the fire from the gate of life of suffering from a deficiency of the kidney, on warm soil spleen is more empty, lower consumption body fluid is not opened entire mistake department for stomach pass, damp and hotly accumulates long-pending large intestine, internal organs gas is unfavorable, coagulation of QI-blood and falling ill.Therefore it shows coldheat complex, deficiency and excess is also shown in, thus the treatment of primary disease must invigorating spleen to remove dampness, invigorating the spleen and replenishing QI, the kidney warming astringing intestine to stop diarrhea, circulation of qi promoting intestinal stasis relieving, by strengthening the body resistance, the principle for the treatment of both the principal and secondary aspects of a disease, this is sick and be difficult for effect of recurrence to reach treatment.
Specific implementation method:
The administering mode of described Chinese medicine composition is oral.
Described Chinese medicine composition dosage form is decoction, powder, tablet, honey refining pill, water and pill, tablet, capsule, oral liquid, granule.
The preparation method of described Chinese medicine composition comprises:
The step of pulverizing: described raw material is mixed by proportioning, drop into pulverizer and be ground into fine powder, granularity is 80-110 order;
The step of mixing: the fine powder of above-mentioned steps gained is dropped into mixing and blending machine and fully mix;
The step of packing: by bottle or packing box subpackage for the fine powder mixing, every 10-20 gram is one bag or a box subpackage.
The pharmacological action of medicine of the present invention is analyzed as follows:
Radix Saposhnikoviae: pungent, sweet, slightly warm in nature, has relieving spasm to stop pain, victory is wet antipruritic, the effect of expelling pathogenic wind from the body surface, for affection of exogenous wind-cold, stomachache is had loose bowels, stool band blood etc., polygamy closes the uses such as the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, return spleen, stomach warp.Cure mainly deficient QI of the spleen and stomach, anorexia, lack of appetite abdominal distention, diarrhea with loose stool, has invigorating the spleen and benefiting QI, dampness diuretic, and strengthening superficial resistance to stop perspiration and antiabortive effect are used for the treatment of abdominal distention diarrhoea, distension and fullness in the abdomen, dysuria etc.
The Radix Paeoniae Alba: cool, bitter, sour, be slightly cold, the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing is received antiperspirant, has antibacterial, antipyretic, spasmolytic antiulcer and analgesic effect, for dysentery stomachache, menalgia, breast abdomen association rib pain, spasm of the limbs pain and uneasy lower limb syndrome etc.
Pericarpium Citri Reticulatae: bitter, pungent, warm.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, cures mainly fullness in the epigastrium and chest due to stagnation of QI in spleen and stomach, lack of appetite and vomiting, dyspepsia, indigestion and loss of appetite loose stool, cough with copious phlegm etc.With the same use of the Rhizoma Atractylodis Macrocephalae, there is effect of tonifying the spleen and stomach.
Radix Codonopsis: flat, sweet, micro-acid, return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, for body due to deficiency of QI in middle-JIAO empty asthenia, anorexia and loose stool, the disease such as thirsty of breathing hard, with air making-up and spleen enlivening, same the using of the sharp dry Rhizoma Atractylodis Macrocephalae of dehumidifying, can improve human body adaptability, antiulcer, increase intestinal tension force, regulate the effect of stomach motion, be clinically usually used in treating chronic diarrhea, ulcerative colitis, chronic atrophic gastritis etc.
Poria: sweet, light, flat, there is promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, anticancer effect relieves internal heat, can invigorating the spleen and regulating the stomach, again can eliminating dampness by diuresis diuresis, be tonifying the spleen and stomach, the good medicine of controlling the deficiency of vital energy, pharmacological research proves that this medical instrument has enhancing immunity, antibacterial, antitumor and calm effect, has treatment and preventive effect to digestive tract ulcer.
Semen Coicis: cool, sweet, light, invigorating spleen to remove dampness, eliminating impediment antidiarrheal, clearing away heat and discharging pus, has the effect of antipyretic, analgesia, antiinflammatory, enhancing immunity, can be used for treating diarrhea due to hypofunction of the spleen, dysuria, the diseases such as acute appendicitis edema.
Semen Myristicae: pungent, bitter, puckery, enter spleen, stomach two warps.Warming middle-JIAO astringing intestine to stop diarrhea, promote qi circulation digestion promoting, cures mainly chronic diarrhea due to Deficiency and coldness of spleen and stomach, cold-dysentery, abdominal distention, lack of appetite vomiting, dyspepsia does not disappear etc., has certain calmness, antiinflammatory action simultaneously.
Fructus Psoraleae: acrid, bitter, warm, enter kidney, spleen channel.Warm spleen antidiarrheal, reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, helping inspiration to relieve asthma.For have loose bowels due to deficiency of spleen-YANG and kidneyYANG and deficiency of kidney-QI due to dyspnea due to deficiency, frequent micturition etc.
Fructus Alpiniae Oxyphyllae: pungent, warm, bitter, return spleen, kidney channel.Warming spleen and stopping diarrha and middle QI invigorating, warming the kidney controlling nocturnal emission with astringent drugs, cures mainly cold type of pain in Deficiency and coldness of spleen and stomach, abdomen, mouthful slavers over more, enuresis due to deficiency of the kidney.There is the effect of certain analgesia, antiulcer and antianaphylaxis.
Fructus Chebulae: bitter, sour, puckery, flat.Enter large intestine, lung, stomach warp; The astringing intestine to stop diarrhea therapeutic method to keep the adverse QI flowing downwards, the sore-throat relieving of astringing the lung, for chronic diarrhea and dysentery, stool band blood, chronic cough aphonia etc., can remove oxygen-derived free radicals in vivo, and dysentery bacterium, Bacillus typhi, shigella dysenteriae etc. are had to obvious inhibitory action.
The Radix Aucklandiae: acrid, bitter, warm, return spleen, stomach, liver, lung meridian.Promoting the circulation of QI to relieve pain, intestinal stasis relieving in tune, can treat the intestines and stomach weakness, and the excessive thirst of having loose bowels, rice indigested food, abdominal swelling, breast side of body painful abdominal mass are vexed, dysentery pus and blood, tenesmus, night rise again and again, limbs asthenia etc.
Fructus Amomi: pungent, temperature, enters spleen, stomach, kidney channel, removing dampness circulation of qi promoting, warming the spleen, antiabortive.There is ulcer, antiplatelet aggregation and the analgesic activity of inhibition, can be used for that retention of damp leading to blockage of QI, distension and fullness in the abdomen, anorexia, stomachache are had loose bowels, pregnancy reactions, frequent fetal movement etc.
Rhizoma Dioscoreae: sweet, flat, enter spleen, lung, kidney channel.Spleen reinforcing, support lung, reinforce the kidney, benefit essence, can blood fat reducing, blood sugar lowering, antioxidation, improve immunity and promote ulcer and wound healing, cure mainly diarrhea due to hypofunction of the spleen, lack of appetite edema, the frequent micturition of suffering from a deficiency of the kidney, seminal emission and be with inferior.
The Radix Linderae: pungent, warm, return spleen, stomach, liver, kidney, urinary bladder channel.Promoting the circulation of QI to relieve pain, warming kidney for dispelling cold, vexed for abdominal distention, fullness in the chest and hypochondrium, headache, dysmenorrhea and puerperal abdonimal pain etc.There is well antibacterial, antiinflammatory, analgesia and suppress the effect of gastrointestinal smooth muscular spasm.
Radix Glycyrrhizae: sweet, flat, return spleen, stomach, the heart, lung meridian.Detoxify, remove distention and fullness in the abdomen, coordinating the actions of various ingredients in a prescription with middle emergency, lung moistening, be used for the treatment of weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool and medicine, alimentary toxicosis etc.
Model case
In certain, man.49 years old, peasant, recurrent diarrhea outbreak more than 20 years, gently every day 3-5 time, heavy more than 10 inferior, often with mucus and pus and blood, and crissum bearing down is obvious.When the colonoscopy prompting sigmoid colon hyperemia of hospital of districts and cities, edema, visible two place's aphtha faces, surface, with white mucus, is diagnosed as chronic ulcerative colitis, through multi-treatment, poor effect, takes medicine of the present invention, and after 1 course for the treatment of, symptom obviously alleviates, after continuing to take half a year, fully recover, follow up a case by regular visits to so far without recurrence.
Grandson, female, 50 years old, stomachache, diarrhoea are shown effect more than 5 years repeatedly, and local hospital colonoscopy is diagnosed as chronic colitis, rear hospitalization, after remission, leave hospital, but after meeting fatigue, anger, just show effect, carry not digest food and white mucus secretly with stomachache, borborygmus, stool, use treatment by Chinese herbs of the present invention transference cure, recovery from illness after 60 days.
Wu, man, 40 years old, often diarrhoea, companion stomachache, borborygmus, slightly slow after rushing down, the greasy or raw and cold diarrhoea of slightly taking food aggravation, day rushes down 3-5 time, often presss from both sides indigestion food and glues and freeze shape liquid, and inappetence, becomes thin weak.Colonoscope is diagnosed as chronic colitis, takes Chinese medicine of the present invention, and pain is rushed down only entirely after 10 doses, then consolidates curative effect after take bimester, follows up a case by regular visits to without recurrence.
Liu, man.35 years old, outbreak stomachache repeatedly, diarrhoea 3 years, be mainly in night, every day 2-4 time, indigestion, lack of appetite abdominal distention, lassitude of the limbs and weakness, time have lower abdomen dull pain, colonoscopy prompting colitis, after taking 5 doses of Chinese medicine decoction of the present invention, all diseases all subtract, and fully recover after continuing to take January.
High certain, man, 36 years old, cadre, diarrhea with loose stool more than 8 years, day 3-4 time, loose stool is not well, is with not digest food and mucus, pus and blood, abdominal distention hypodynia, inappetence, body constitution is become thin; Examine as chronic colitis through local hospital colonoscopy, take Chinese medicine pill of the present invention, orally taken for curing was fully recovered after 3 months.After 1 year, follow up a case by regular visits to without recurrence.
Therapeutic effect is formulated with reference to " Chinese medicine Clinical Researches of New Drugs guideline ": recovery from illness: clinical symptoms, sign disappear, and fibro-colonoscope check is normal, and it is normal that intestinal mucosa pathological changes is recovered; Effective: clinical symptoms obviously alleviates, sign disappears substantially, and fibro-colonoscope check takes a turn for the better, and intestinal mucosa pathological changes is obviously improved; Invalid: before and after treatment, clinical symptoms and sign are without improvement, and fibro-colonoscope check is without taking a turn for the better.
Treat altogether patient 121 people, male 93 people, female 28 people, age distribution is in 25-68 year, and all per rectum mirror is diagnosed as colitis.Through taking Chinese medicine of the present invention, clinical cure 99 examples (81.8%), effective 12 examples (9.9%), total effective rate is 91.7%.
Claims (5)
1. a Chinese medicine composition for the treatment of chronic colitis, is characterized in that, it is to be made up of the herbal raw material of following ratio of weight and number: Radix Saposhnikoviae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Paeoniae Alba 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Radix Codonopsis 10-30 part, Poria 10-30 part, Semen Coicis 20-40 part, Semen Myristicae 5-15 part, Fructus Psoraleae 10-20 part, Fructus Alpiniae Oxyphyllae 10-20 part, Fructus Chebulae 5-15 part, Radix Aucklandiae 5-15 part, Fructus Amomi 5-15 part, Rhizoma Dioscoreae 10-30 part, Radix Linderae 5-15 part, Radix Glycyrrhizae 5-20 part.
2. the Chinese medicine composition for the treatment of according to claim 1 chronic colitis, is characterized in that, the optimum weight portion rate of various raw materials is: Radix Saposhnikoviae 10-15 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Radix Paeoniae Alba 10-15 part, Pericarpium Citri Reticulatae 10-15 part, Radix Codonopsis 15-30 part, Poria 10-20 part, Semen Coicis 25-35 part, Semen Myristicae 8-12 part, Fructus Psoraleae 10-15 part, Fructus Alpiniae Oxyphyllae 15-20 part, Fructus Chebulae 8-12 part, Radix Aucklandiae 8-12 part, Fructus Amomi 10-15 part, Rhizoma Dioscoreae 15-20 part, Radix Linderae 8-12 part, Radix Glycyrrhizae 10-15 part.
3. according to the Chinese medicine composition for the treatment of chronic colitis described in claim 1 and 2, it is characterized in that, described Chinese medicine composition dosage form is decoction, powder, honeyed pill, the watered pill, tablet, capsule, oral liquid, electuary.
4. according to the Chinese medicine composition for the treatment of chronic colitis described in claim 1 and 2, it is characterized in that, the administering mode of described Chinese medicine composition is oral.
5. the Chinese medicine composition for the treatment of according to claim 3 chronic colitis, is characterized in that, the preparation method of described Chinese medicine composition composition powders comprises:
The step of pulverizing: described raw material is mixed by proportioning, drop into pulverizer and be ground into fine powder, granularity is 80-110 order;
The step of mixing: the fine powder of above-mentioned steps gained is dropped into mixing and blending machine and fully mix;
The step of packing: by bottle or packing box subpackage for the fine powder mixing, every 10-20 gram is one bag or a box subpackage.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104162060A (en) * | 2014-08-15 | 2014-11-26 | 刘振声 | Traditional Chinese medicinal preparation for treating colitis |
| CN105056003A (en) * | 2015-09-05 | 2015-11-18 | 南京正宽医药科技有限公司 | Medicinal preparation for treating chronic colitis |
| CN105381021A (en) * | 2015-12-23 | 2016-03-09 | 刘可 | Traditional Chinese medicine composition for treating chronic colitis and preparation method and application thereof |
| CN106237229A (en) * | 2016-08-31 | 2016-12-21 | 亳州市庆聚药业销售有限公司 | A kind of Chinese medicine composition treating chronic colitis |
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| JP2004115536A (en) * | 2003-11-27 | 2004-04-15 | Rohto Pharmaceut Co Ltd | Anti-helicobacter pylori activator |
| CN103432501A (en) * | 2013-09-10 | 2013-12-11 | 孙丰卿 | Traditional Chinese medicine composition for treating chronic colitis and preparation method of preparation thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104162060A (en) * | 2014-08-15 | 2014-11-26 | 刘振声 | Traditional Chinese medicinal preparation for treating colitis |
| CN105056003A (en) * | 2015-09-05 | 2015-11-18 | 南京正宽医药科技有限公司 | Medicinal preparation for treating chronic colitis |
| CN105381021A (en) * | 2015-12-23 | 2016-03-09 | 刘可 | Traditional Chinese medicine composition for treating chronic colitis and preparation method and application thereof |
| CN106237229A (en) * | 2016-08-31 | 2016-12-21 | 亳州市庆聚药业销售有限公司 | A kind of Chinese medicine composition treating chronic colitis |
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