CN103800786B - A kind of compound Chinese medicinal preparation for the treatment of gastropathy - Google Patents
A kind of compound Chinese medicinal preparation for the treatment of gastropathy Download PDFInfo
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- CN103800786B CN103800786B CN201410070948.4A CN201410070948A CN103800786B CN 103800786 B CN103800786 B CN 103800786B CN 201410070948 A CN201410070948 A CN 201410070948A CN 103800786 B CN103800786 B CN 103800786B
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Abstract
The present invention relates to a kind of compound Chinese medicinal preparation for the treatment of gastropathy, belong to the field of Chinese medicines.This compound Chinese medicinal preparation is prepared from according to certain weight proportion by crude drug Pericarpium Citri Reticulatae, Olibanum, Folium Artemisiae Argyi, Fructus Tribuli, Semen Raphani, Folium Perillae, Radix Notoginseng, Sorghum vulgare Pers. Rhizoma Zingiberis Recens and Radix Glycyrrhizae, described preparation can be the dosage forms such as tablet, pill, granule or capsule, and it is had a pain for weakness of the spleen and stomach, cold syndrome of the stomach, the disease such as hyperchlorhydria, gastric and duodenal ulcers has good therapeutical effect.
Description
Technical field
The present invention relates to a kind of compound Chinese medicinal preparation for the treatment of gastropathy, more particularly, relate to a kind ofly treat weakness of the spleen and stomach, the Chinese medicine composition of the disease such as cold syndrome of the stomach is had a pain, hyperchlorhydria, gastric and duodenal ulcers and preparation method thereof.
Background technology
Peptic Ulcers is a kind of common chronic systemic disease, is divided into gastric ulcer and duodenal ulcer, is called peptic ulcer again.Peptic ulcer is mainly formed mucosa autodigestion due to gastric acid and pepsin.Peptic Ulcers with the rhythmicity upper abdominal pain of recurrent exerbation for clinical characters, often with belch, return acid, the sensation such as scorching hot, noisy, even also have Nausea and vomiting, hematemesis, have blood in stool.Circle, oval chronic ulcer is had in gastrointestinal local.The sickness rate of Peptic Ulcers increases year by year in recent years, and this course of disease is longer, normal recurrent exerbation, does not touchingly heal.If therapeutic effect is not obvious, often there is violent stomachache, the complication such as gastrorrhagia, gastric perforation, pyloric obstruction can be caused to occur, also have severe patient to develop into canceration.
The chemical drugs that current treatment peptic ulcer is conventional has bismuth aluminate compound, cimetidine, ranitidine, omeprazole etc., but often expensive, and long-term taking has certain side effect; Conventional Chinese patent medicine has KUAIWEI PIAN, Fuzi Lizhong Wan etc., but the prescription of above-mentioned Chinese patent medicine and stress face difference, also very large to the curative effect difference of dissimilar Peptic Ulcers.
Summary of the invention
The present invention, according to Traditional Chinese Medicine theory, has invented a kind of Chinese medicine composition, can treat weakness of the spleen and stomach, the disease such as cold syndrome of the stomach is had a pain, hyperchlorhydria, gastric and duodenal ulcers, has instant effect, good analgesic effect, and the feature such as have no adverse reaction.
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of gastropathy.
Another object of the present invention is to provide the preparation method of this Chinese medicine composition.
For achieving the above object, the invention provides following technical scheme:
The invention provides a kind of Chinese medicine composition for the treatment of gastropathy, it is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 1-25 part Olibanum 1-10 part Folium Artemisiae Argyi 1-15 part
Fructus Tribuli 1-15 part Semen Raphani 1-15 part Folium Perillae 1-15 part
Radix Notoginseng 1-15 part Rhizoma Alpiniae Officinarum 1-15 part Radix Glycyrrhizae 1-10 part.
Preferably, the invention provides a kind of Chinese medicine composition for the treatment of gastropathy, it is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 2-20 part Olibanum 1-8 part Folium Artemisiae Argyi 1-10 part
Fructus Tribuli 1-10 part Semen Raphani 1-10 part Folium Perillae 1-10 part
Radix Notoginseng 1-10 part Rhizoma Alpiniae Officinarum 1-10 part Radix Glycyrrhizae 1-8 part.
More preferably, the invention provides a kind of Chinese medicine composition for the treatment of gastropathy, it is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 5-18 part Olibanum 1-5 part Folium Artemisiae Argyi 1-8 part
Fructus Tribuli 1-8 part Semen Raphani 1-8 part Folium Perillae 1-8 part
Radix Notoginseng 1-8 part Rhizoma Alpiniae Officinarum 1-8 part Radix Glycyrrhizae 1-5 part.
Particularly preferably, the invention provides a kind of Chinese medicine composition for the treatment of gastropathy, it is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 8 parts of Olibanums 2 portions of Folium Artemisiae Argyis 4 parts
Fructus Tribuli 4 parts of Semen Raphanis 4 parts of Folium Perillaes 4 parts
2 parts, Radix Notoginseng 4 portions of Rhizoma Alpiniae Officinarums 4 portions of Radix Glycyrrhizaes.
In Chinese medicine composition of the present invention, with Pericarpium Citri Reticulatae, Olibanum, Folium Artemisiae Argyi for monarch drug, regulating qi-flowing for harmonizing stomach; Minister is with Fructus Tribuli, Semen Raphani, Folium Perillae, and above-mentioned three taste medicines share, and monarch drug can be assisted to strengthen treatment qi depression to blood stasis, stomach network damaging conditions; With Radix Notoginseng, Rhizoma Alpiniae Officinarum for adjuvant drug, Radix Glycyrrhizae is for making medicine.
Above-mentioned nine taste medicines share, and cold and heat are also adjusted, giving consideration to both the incidental and fundamental, can make the strong fortune of taste, stagnation resolvation stagnantization, stomach network recovering of injured, and all diseases are from removing.
Chinese medicine composition of the present invention, by above crude drug, in conjunction with modern Chinese medicine preparation process, can make clinical required various dosage forms, such as tablet, pill, granule and capsule.
On the other hand, the invention provides a kind of method preparing above-mentioned Chinese medicine composition, comprise the steps:
(1) crude drug taking described weight proportion is for subsequent use;
(2) above nine taste medicine mixed powders are broken into fine powder, cross 100-300 mesh sieve; Abundant mix homogeneously, obtains mixture;
(3) said mixture is added pharmaceutically acceptable adjuvant, conveniently the preparation method of preparation makes required dosage form.
The preparation method of above-described conventional formulation refers to what pharmaceutics those of ordinary skill was grasped, or can from document and textbook learning to the general technology of preparing of related preparations.
Again on the one hand, the invention provides the purposes of above-mentioned Chinese medicine composition in the medicine of preparation treatment gastropathy.
Detailed description of the invention
Exploitativeness of the present invention is further described below by embodiment; for a person skilled in the art; should be understood to, the following examples are not limiting the scope of the invention, still belong to protection scope of the present invention to the equivalent replacement of some technical characteristic.
Embodiment 1
Prescription: Pericarpium Citri Reticulatae 600g Olibanum 150g Folium Artemisiae Argyi 300g
Fructus Tribuli 300g Semen Raphani 300g Folium Perillae 300g
Radix Notoginseng 300g Rhizoma Alpiniae Officinarum 300g Radix Glycyrrhizae 150g
Method for making: the crude drug taking described weight proportion is for subsequent use; Above nine taste medicine mixed powders are broken into fine powder, cross 150 mesh sieves; Abundant mix homogeneously, obtains mixture; Said mixture is added appropriate magnesium stearate, is pressed into plain sheet, make 9000 altogether, film coating, to obtain final product.
Embodiment 2
Prescription: Pericarpium Citri Reticulatae 700g Olibanum 200g Folium Artemisiae Argyi 300g
Fructus Tribuli 300g Semen Raphani 300g Folium Perillae 300g
Radix Notoginseng 250g Rhizoma Alpiniae Officinarum 300g Radix Glycyrrhizae 150g
Method for making: the crude drug taking described weight proportion is for subsequent use; Above nine taste medicine mixed powders are broken into fine powder, cross 200 mesh sieves; Abundant mix homogeneously, obtains mixture; Said mixture is loaded in hard capsule, make 9000 altogether, to obtain final product.
Embodiment 3
Prescription: Pericarpium Citri Reticulatae 1500g Olibanum 300g Folium Artemisiae Argyi 600g
Fructus Tribuli 600g Semen Raphani 600g Folium Perillae 600g
Radix Notoginseng 600g Rhizoma Alpiniae Officinarum 600g Radix Glycyrrhizae 150g
Method for making: the crude drug taking described weight proportion is for subsequent use; Above nine taste medicine mixed powders are broken into fine powder, cross 200 mesh sieves; Abundant mix homogeneously, obtains mixture; Said mixture is added appropriate amylum pregelatinisatum, makes pill, to obtain final product.
The beneficial effect of medicine of the present invention is set forth further below by clinical trial
The tablet that Example 1 is made carries out clinical trial
The routine patient of clinical observation 80, is diagnosed as active stage ulcer through gastroscopy, and Syndrome Differentiation of Traditional Chinese Medicine is asthenic cold type gastric abscess.Each oral meal 2-4 sheet, every day three times, medicine time is 3 weeks, after 3 weeks, carry out traditional Chinese medical science four diagnostic methods dialectical Analyses and fibergastroscopy.In 80 routine cases, all occur the symptoms such as nausea and vomiting in various degree, acid regurgitation, abdominal distention, after taking medicine of the present invention, above-mentioned symptom disappearance 62 is routine, and take a turn for the better 14 examples, and total effective rate is 95%.Gastroscopy result shows, clinical cure 55 example in promotion ulcer healing, and effective 20 examples, total effective rate is 93.75%.
The hard capsule that Example 2 is made carries out clinical trial
The routine patient of clinical observation 100, is diagnosed as active stage ulcer through gastroscopy, and Syndrome Differentiation of Traditional Chinese Medicine is asthenic cold type gastric abscess.Each oral meal 4-6 grain, every day three times, medicine time is 4 weeks, after 4 weeks, carry out traditional Chinese medical science four diagnostic methods dialectical Analyses and fibergastroscopy.In 100 routine cases, all have the symptoms such as pain in various degree, nausea and vomiting, acid regurgitation, abdominal distention, after taking medicine of the present invention, pain disappearance 65 is routine, and take a turn for the better 25 examples, and total effective rate is 90%.Gastroscopy result shows, clinical cure 67 example in promotion ulcer healing, and effective 25 examples, total effective rate is 92%.
The pill that Example 3 is made carries out clinical trial
The routine patient of clinical observation 100, is diagnosed as active stage ulcer through gastroscopy, and Syndrome Differentiation of Traditional Chinese Medicine is asthenic cold type gastric abscess.Each oral meal 2 bags (4g), every day three times, medicine time is 3 weeks, after 3 weeks, carry out traditional Chinese medical science four diagnostic methods dialectical Analyses and fibergastroscopy.In 100 routine cases, all have the symptoms such as pain in various degree, nausea and vomiting, acid regurgitation, abdominal distention, after taking medicine of the present invention, pain disappearance 67 is routine, and take a turn for the better 25 examples, and total effective rate is 92%.Gastroscopy result shows, clinical cure 71 example in promotion ulcer healing, and effective 18 examples, total effective rate is 89%.
Content of the present invention merely illustrates some claimed specific embodiments; one of them or more described technical characteristic can be combined with arbitrary one or more technical scheme in technical scheme; these technical schemes obtained through combination also in the application's protection domain, just as these technical schemes obtained through combination in the disclosure of invention concrete record.
Claims (7)
1. treat a Chinese medicine composition for gastropathy, it is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 1-25 part Olibanum 1-10 part Folium Artemisiae Argyi 1-15 part
Fructus Tribuli 1-15 part Semen Raphani 1-15 part Folium Perillae 1-15 part
Radix Notoginseng 1-15 part Rhizoma Alpiniae Officinarum 1-15 part Radix Glycyrrhizae 1-10 part.
2. Chinese medicine composition according to claim 1, is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 2-20 part Olibanum 1-8 part Folium Artemisiae Argyi 1-10 part
Fructus Tribuli 1-10 part Semen Raphani 1-10 part Folium Perillae 1-10 part
Radix Notoginseng 1-10 part Rhizoma Alpiniae Officinarum 1-10 part Radix Glycyrrhizae 1-8 part.
3. Chinese medicine composition according to claim 2, is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 5-18 part Olibanum 1-5 part Folium Artemisiae Argyi 1-8 part
Fructus Tribuli 1-8 part Semen Raphani 1-8 part Folium Perillae 1-8 part
Radix Notoginseng 1-8 part Rhizoma Alpiniae Officinarum 1-8 part Radix Glycyrrhizae 1-5 part.
4. Chinese medicine composition according to claim 3, is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Pericarpium Citri Reticulatae 8 parts of Olibanums 2 portions of Folium Artemisiae Argyis 4 parts
Fructus Tribuli 4 parts of Semen Raphanis 4 parts of Folium Perillaes 4 parts
2 parts, Radix Notoginseng 4 portions of Rhizoma Alpiniae Officinarums 4 portions of Radix Glycyrrhizaes.
5. a Chinese medicine preparation, is characterized in that the Chinese medicine composition described in any one of Claims 1-4 to make tablet, pill, granule or capsule.
6. the preparation method of Chinese medicine preparation as claimed in claim 5, is characterized in that, comprise the steps:
(1) crude drug taking described weight proportion is for subsequent use;
(2) each crude drug mixed powder is broken into fine powder, crosses 100-300 mesh sieve; Abundant mix homogeneously, obtains mixture;
(3) said mixture is added pharmaceutically acceptable adjuvant, conveniently the preparation method of preparation makes tablet, pill, granule or capsule.
7. the purposes of the Chinese medicine composition described in any one of claim 1-4 in the medicine of preparation treatment gastropathy.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410070948.4A CN103800786B (en) | 2014-02-28 | 2014-02-28 | A kind of compound Chinese medicinal preparation for the treatment of gastropathy |
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| CN201410070948.4A CN103800786B (en) | 2014-02-28 | 2014-02-28 | A kind of compound Chinese medicinal preparation for the treatment of gastropathy |
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| CN103800786A CN103800786A (en) | 2014-05-21 |
| CN103800786B true CN103800786B (en) | 2016-03-02 |
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| CN105535784A (en) * | 2016-01-07 | 2016-05-04 | 大连大学 | Traditional Chinese medicine composition for treating stomach illness and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101417110A (en) * | 2008-11-21 | 2009-04-29 | 冯书德 | Pill formulation capable of strengthening the spleen and stomach and preparation method thereof |
| CN102631619A (en) * | 2012-04-10 | 2012-08-15 | 丰建君 | Traditional Chinese medicines for treating chronic superficial gastritis |
| CN102847048A (en) * | 2012-09-27 | 2013-01-02 | 冯书德 | Medicine for treating superficial gastritis and preparation method thereof |
| CN103055173A (en) * | 2012-12-06 | 2013-04-24 | 潍坊圣仁药业有限公司 | Preparation method for medicine for treating gastric ulcer |
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2014
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101417110A (en) * | 2008-11-21 | 2009-04-29 | 冯书德 | Pill formulation capable of strengthening the spleen and stomach and preparation method thereof |
| CN102631619A (en) * | 2012-04-10 | 2012-08-15 | 丰建君 | Traditional Chinese medicines for treating chronic superficial gastritis |
| CN102847048A (en) * | 2012-09-27 | 2013-01-02 | 冯书德 | Medicine for treating superficial gastritis and preparation method thereof |
| CN103055173A (en) * | 2012-12-06 | 2013-04-24 | 潍坊圣仁药业有限公司 | Preparation method for medicine for treating gastric ulcer |
Non-Patent Citations (1)
| Title |
|---|
| 辨证论治胃痞证86例分析;杨彦生;《甘肃中医》;20020830;第15卷(第04期);第33-35页 * |
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