CN103800716A - Traditional Chinese medicine for treating otogenic brain abscess - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating otogenic brain abscess, belonging to the technical field of traditional Chinese medicine. The traditional Chinese medicine for treating otogenic brain abscess is characterized in that a raw pharmaceutical material of the traditional Chinese medicine contains the following ingredients in parts by weight: 6-20 parts of radix trichosanthis, 6-15 parts of Zhejiang fritillary bulb, 5-15 parts of phellodendron bark, 5-15 parts of dahurian angelica root, 6-12 parts of honeysuckle flower, 3-10 parts of tangerine peel, 4-15 parts of radish seed, 3-9 parts of tuckahoe, 5-15 parts of borneol, 3-10 parts of polygonatum odoratum and 5-15 parts of reed rhizome. The traditional Chinese medicine preparation disclosed by the invention is safe, reliable and effective and is free from toxic and side effects.

Description

A kind of Chinese medicine for the treatment of otogenic brain abscess

Technical field

The present invention relates to a kind of Chinese medicine for the treatment of otogenic brain abscess, belong to technical field of Chinese medicines.

Background technology

Otogenic brain abscess is gathered by the pus in the concurrent cerebral tissue of suppurative features of chronic otitis media.

The formation of brain abscess generally can be divided into limitation encephalitis phase, stadium suppurations and peplos and form phase three phases, forms easily serious ventriculitis and the meningitis of formation of phase at peplos.Even cause fatal fulminant meningitis.If intracranial pressure obviously raises.Cerebral tissue is shifted.Form cerebral hernia.Often there is herniation of the cerebellar incisura tentori in temporal lobe abscess.Cerebellar abscess is common with transforminal herniation.Can occur breathing.Cardiac arrest and dead rapidly.

Treat clinically at present otogenic brain abscess the general main employing of light disease be a large amount of sensitivity antibiotic and sulfa drugss, antibiotic use makes patient body produce larger Drug resistance, patient's health has often been produced to larger toxic and side effects, and therapeutic effect is undesirable.Patient with severe symptoms must adopt operative treatment, and expense is high, has a big risk, and patient suffering is large.

Summary of the invention

The present invention aims to provide the Chinese medicine of a kind of safe and reliable, evident in efficacy, treatment no pain, the treatment otogenic brain abscess that has no side effect, this Chinese medicine, by selecting rationally effectively raw medicinal material and proportioning thereof, reaches the object of safe and effective healing otogenic brain abscess.

The present invention is achieved by the following technical solutions:

A kind of Chinese medicine for the treatment of otogenic brain abscess, special character is, formulated by the crude drug of following weight proportion: Radix Trichosanthis 6-20 part, Bulbus Fritillariae Thunbergii 6-15 part, Cortex Phellodendri 5-15 part, Radix Angelicae Dahuricae 5-15 part, Flos Lonicerae 6-12 part, Pericarpium Citri Reticulatae 3-10 part, Semen Raphani 4-15 part, Poria 3-9 part, Borneolum Syntheticum 5-15 part, Rhizoma Polygonati Odorati 3-10 part, Rhizoma Phragmitis 5-15 part.

More excellent raw material components is chosen as: 12 parts of Radix Trichosanthis, 8 parts of Bulbus Fritillariae Thunbergiis, 10 parts of Cortex Phellodendris, 10 parts of the Radixs Angelicae Dahuricae, 8 parts of Flos Loniceraes, 6 parts of Pericarpium Citri Reticulataes, 8 parts of Semen Raphani, 6 parts, Poria, 10 parts of Borneolum Syntheticums, 8 parts of Rhizoma Polygonati Odorati, 7 parts of Rhizoma Phragmitiss.

Radix Trichosanthis: sweet in the mouth, micro-hardship, be slightly cold.Attach to the lung and stomach meridians.For the root of cucurbitaceous plant Chinese juniper beach wormwood, be clearing away heat-fire class medicine, its concrete effect is clearing away heat-fire, promoting the production of body fluid to quench thirst, evacuation of pus detumescence.Cure mainly: control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.

Bulbus Fritillariae Thunbergii: the large hardship of taste, cold in nature.Removing heat-phlegm, powder detoxifcation.Control cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.

Cortex Phellodendri: nature and flavor: hardship; Cold.Gui Jing: kidney channel; Bladder; Large intestine channel.Function: heat and toxic materials clearing away medicine; Heat clearing and dampness removing medicine.Cure mainly: hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia; Hectic fever due to YIN-deficiency consumptive fever, night sweat; And aphtha of the mouth and tongue; Conjunctival congestion and swelling pain; Skin sore.

The Radix Angelicae Dahuricae: warm in nature, acrid in the mouth.Wind-damp dispelling, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving.For headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.The cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Expelling pathogenic wind from the body surface: for cold, the cards such as headache, nasal obstruction, have dispersing wind and cold, an effect of the pain that relieves the pain.Wind-expelling pain-stopping: for wind syndrome of head pain, migraine, supraorbital bone pain, nasosinusitis headache, tooth pain etc., can wind-expelling pain-stopping.Dissipation evacuation of pus: with controlling carbuncle skin infection, from the beginning of dissipating, can evacuation of pus after bursting.A surname's clearing the nasal passage: for the long stream of turbid tears of nasal sinusitis, anosmia person.

Flos Lonicerae: sweet, micro-hardship, delicate fragrance, pungent, cold.Return lung, stomach, the heart, large intestine channel.For Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or the first flower of opening of band.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.The sweet cold fragrance of its property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, and for various febrile diseases, as fever of the body, dermexanthesis, send out the cards such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.

Semen Raphani: pungent, sweet, flat.Return lung, spleen, stomach warp.Dyspepsia and intestinal stasis relieving; Lowering the adverse-rising QI to resolve phlegm.Main stagnation of QI due to dyspepsia; Distension and fullness in the abdomen; Diarrhoea; Heavy after dysentery; Cough ant phlegm; QI rising in reverse order dyspnea with fullness of the chest.The fatty oil of Semen Raphani, volatile oil.In volatile oil, there is methanthiol etc.In fatty oil, contain volume erucic acid, linoleic acid, linolenic acid and glycerol sinapate etc.Semen Raphani is containing antibiotic substance, and its effective ingredient is raphanin, the secret escherichia coli of staphylococcus is had and is showing inhibitory action, and can affect various plant seed germinations.After from Semen Raphani, isolate again a kind of oil, can be to growths such as streptococcus, pyococcus, streptococcus pneumoniae, escherichia coli.

Pericarpium Citri Reticulatae: warm in nature, acrid in the mouth, bitter in the mouth.Enter spleen channel, stomach warp, lung meridian.Regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia.Abdominal distention uncomfortable in chest, indigestion and loss of appetite loose stool in turbid damp resistance.Phlegm-damp is stopped up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Pericarpium Citri Reticulatae has three major types effect, and the one, lead cold-evil in the heart, two broken stagnant gas, three strengthening the spleen stomaches.This three greatly on, Main Function is row QI of the spleen and stomach.The main transmitting and distributing the fluids of taste, therefore QI of the spleen and stomach capablely can dry, spleen invigorating, reduce phlegm, therefore can say again, Pericarpium Citri Reticulatae temperature can be supported spleen, pungent can being amusing, bitter can spleen invigorating.Due to the main row QI of the spleen and stomach of Pericarpium Citri Reticulatae, taste are located in middle Jiao, and middle Jiao's gas is current, and the gas of three warmers is also sprung up thereupon.Three warmers are the organ in charge of water circulation, and current water liquid, accompanies with wetting phase; Again for hiding mansion outside mansion, the upper and heart, lung, lower and liver, kidney.So the effect of Pericarpium Citri Reticulatae can wide and all Zang Fu, spread all over whole body wet.

Poria: ancients claim that Poria is " god medicine " at 4 o'clock, because its effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, no matter cold, temperature, wind, all diseases that wets can be brought into play its unique effects.The property of medicine is gentle, dampness removing and do not hinder healthy energy.For cough due to fluid-retention, phlegm-damp enters network, and aching pain in should and back Poria can promoting diuresis to eliminate damp pathogen, has again a function of invigorating spleen, for insufficiency of the spleen can not transmitting and distributing the fluids, stop the disease of the raw phlegm retention of dimerization, there is therapeutical effect.

Borneolum Syntheticum: arduous, cool.Enter the heart, lung meridian.Logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.Control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.

Rhizoma Polygonati Odorati: sweet in the mouth, property is flat.Return lung; Stomach warp.Nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of the cloudy liquid consumption of calentura wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.

Rhizoma Phragmitis: nature and flavor are sweet, cold.Return lung meridian, stomach warp.Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.

Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:

1, physical data

Inventor has collected the out-patient of 85 routine otogenic brain abscess altogether between JIUYUE to 2012 year JIUYUE from 2010, wherein male 45 examples, and female's 40 examples, before all patients are the peplos formation phase.Age 30-68 year, course of disease 1-3 month.85 routine patients are divided at random: treatment group 55 examples, matched group 30 examples.Two groups of patients' the data such as age, the course of disease, without significant difference, has comparability.

2, test method

2.1, the routine oral antibiotic of matched group 30 and sulfa drugs, by specification is taken, one month course for the treatment of.

2.2, treatment group 55 example adopts oral patent medicine of the present invention, the morning, noon and afternoon respectively once, one month course for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1, criterion of therapeutical effect

Recovery from illness: clinical symptoms all disappears, and lab testing project is normal.Take a turn for the better: clinical symptom relief, lab testing improves or be normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of, and lab testing is without improvement.

3.2, treatment statistical result is in table 1

The Comparison of therapeutic of table 1 treatment group and matched group

Group	Case load	Recovery from illness	Take a turn for the better	Invalid	Total effective rate (%)
						Treatment group	55	38（69%）	12（22%）	5（9%）	91%
Matched group	30	15（50%）	6（20%）	9（30%）	70%

Show by above-mentioned experimental data, the medicine that the present invention makes can be pacified effective treatment otogenic brain abscess entirely.

The specific embodiment

In order to understand better and to implement the present invention, below in conjunction with the specific embodiment, be used for formation of the present invention to be further described.

Embodiment 1

Take: 6 grams of Radix Trichosanthis, 6 grams of Bulbus Fritillariae Thunbergiis, 5 grams of Cortex Phellodendris, 5 grams of the Radixs Angelicae Dahuricae, 12 grams of Flos Loniceraes, 3 grams of Pericarpium Citri Reticulataes, 15 grams of Semen Raphani, 3 grams, Poria, 5 grams of Borneolum Syntheticums, 3 grams of Rhizoma Polygonati Odorati, 5 grams of Rhizoma Phragmitiss, the decocting that adds 6 times of amounts boils 1.5-2 hour, filtrate for later use after filtration, the decocting that filtering residue adds 6 times of amounts again boils 1-1.5 hour, the filtrate of filtering and the filtrate of last time merge, after concentrated, carry out dry packing, must meet the powder of one day consumption of normal adult.

Instructions of taking and dose are: morning, noon and afternoon every day take for three times.

Embodiment 2

Take: 20 grams of Radix Trichosanthis, 15 grams of Bulbus Fritillariae Thunbergiis, 15 grams of Cortex Phellodendris, 15 grams of the Radixs Angelicae Dahuricae, 12 grams of Flos Loniceraes, 10 grams of Pericarpium Citri Reticulataes, 15 grams of Semen Raphani, 9 grams, Poria, 15 grams of Borneolum Syntheticums, 10 grams of Rhizoma Polygonati Odorati, 15 grams of Rhizoma Phragmitiss, the decocting that adds 6 times of amounts boils 1.5-2 hour, filtrate for later use after filtration, the decocting that filtering residue adds 6 times of amounts again boils 1-1.5 hour, the filtrate of filtering and the filtrate of last time merge, after concentrated, be dried, then add appropriate dextrin and correctives, after granulating according to this area common process, pack, must meet the granule of one day consumption of normal adult.

Embodiment 3

Take: 12 grams of Radix Trichosanthis, 8 grams of Bulbus Fritillariae Thunbergiis, 10 grams of Cortex Phellodendris, 10 grams of the Radixs Angelicae Dahuricae, 8 grams of Flos Loniceraes, 6 grams of Pericarpium Citri Reticulataes, 8 grams of Semen Raphani, 6 grams, Poria, 10 grams of Borneolum Syntheticums, 8 grams of Rhizoma Polygonati Odorati, 7 grams of Rhizoma Phragmitiss.Preparation method is with embodiment 2.

Claims (2)

1. treat the Chinese medicine of otogenic brain abscess for one kind, be characterised in that, formulated by the crude drug of following weight proportion: Radix Trichosanthis 6-20 part, Bulbus Fritillariae Thunbergii 6-15 part, Cortex Phellodendri 5-15 part, Radix Angelicae Dahuricae 5-15 part, Flos Lonicerae 6-12 part, Pericarpium Citri Reticulatae 3-10 part, Semen Raphani 4-15 part, Poria 3-9 part, Borneolum Syntheticum 5-15 part, Rhizoma Polygonati Odorati 3-10 part, Rhizoma Phragmitis 5-15 part.

2. a kind of Chinese medicine for the treatment of otogenic brain abscess as claimed in claim 1, be characterised in that, formulated by the crude drug of following weight proportion: 12 parts of Radix Trichosanthis, 8 parts of Bulbus Fritillariae Thunbergiis, 10 parts of Cortex Phellodendris, 10 parts of the Radixs Angelicae Dahuricae, 8 parts of Flos Loniceraes, 6 parts of Pericarpium Citri Reticulataes, 8 parts of Semen Raphani, 6 parts, Poria, 10 parts of Borneolum Syntheticums, 8 parts of Rhizoma Polygonati Odorati, 7 parts of Rhizoma Phragmitiss.