CN103782301B - 用于基于网络的生物活性评估的系统与方法 - Google Patents

用于基于网络的生物活性评估的系统与方法 Download PDF

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CN103782301B
CN103782301B CN201280043499.3A CN201280043499A CN103782301B CN 103782301 B CN103782301 B CN 103782301B CN 201280043499 A CN201280043499 A CN 201280043499A CN 103782301 B CN103782301 B CN 103782301B
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network
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CN103782301A (zh
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F·马丁
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Philip Morris Products SA
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
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  • Biomedical Technology (AREA)
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  • Primary Health Care (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201280043499.3A 2011-09-09 2012-09-07 用于基于网络的生物活性评估的系统与方法 Active CN103782301B (zh)

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CN201710237916.2A CN107391961B (zh) 2011-09-09 2012-09-07 用于基于网络的生物活性评估的系统与方法

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US201161532972P 2011-09-09 2011-09-09
US61/532,972 2011-09-09
PCT/EP2012/003760 WO2013034300A2 (en) 2011-09-09 2012-09-07 Systems and methods for network-based biological activity assessment

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CN103782301B true CN103782301B (zh) 2017-05-17

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US (1) US20140214336A1 (https=)
EP (1) EP2754075A2 (https=)
JP (3) JP6138793B2 (https=)
CN (2) CN103782301B (https=)
WO (1) WO2013034300A2 (https=)

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EP2608122A1 (en) 2011-12-22 2013-06-26 Philip Morris Products S.A. Systems and methods for quantifying the impact of biological perturbations
CN104508671B (zh) 2012-06-21 2018-10-19 菲利普莫里斯生产公司 通过偏差校正和分类预测生成生物标记签名的系统和方法
CN104584022B (zh) 2012-06-21 2018-11-16 菲利普莫里斯生产公司 一种生成生物标记签名的系统及方法
EP2989578B1 (en) * 2013-04-23 2023-03-29 Philip Morris Products S.A. Systems and methods for using mechanistic network models in systems toxicology
CN105940421B (zh) * 2013-08-12 2020-09-01 菲利普莫里斯生产公司 用于生物网络的人群验证的系统和方法
US10842444B2 (en) 2013-09-13 2020-11-24 Philip Morris Products S.A. Systems and methods for evaluating perturbation of xenobiotic metabolism
EP3158487A1 (en) * 2014-06-20 2017-04-26 Connecticut Children's Medical Center Automated cell culture system and corresponding methods
CN104298593B (zh) * 2014-09-23 2017-04-26 北京航空航天大学 一种基于复杂网络理论的soa系统可靠性评价方法
KR101721528B1 (ko) * 2015-05-28 2017-03-31 아주대학교산학협력단 질병 네트워크로부터 동반 발병 확률을 제공하는 방법
US20170059554A1 (en) * 2015-09-02 2017-03-02 R. J. Reynolds Tobacco Company Method for monitoring use of a tobacco product
CN107480467B (zh) * 2016-06-07 2020-11-03 王�忠 一种判别或比较药物作用模块的方法
CN107992720B (zh) * 2017-12-14 2021-08-03 浙江工业大学 基于共表达网络的癌症靶向标志物测绘方法
TWI693612B (zh) * 2018-01-10 2020-05-11 國立臺灣師範大學 環境賀爾蒙與人體基因的關聯性運算平台
CN108614536B (zh) * 2018-06-11 2020-10-27 云南中烟工业有限责任公司 一种卷烟制丝工艺关键因素的复杂网络构建方法
US11515005B2 (en) * 2019-02-25 2022-11-29 International Business Machines Corporation Interactive-aware clustering of stable states
CN110706749B (zh) * 2019-09-10 2022-06-10 至本医疗科技（上海）有限公司 一种基于组织器官分化层次关系的癌症类型预测系统和方法
WO2023193935A1 (en) * 2022-04-08 2023-10-12 NEC Laboratories Europe GmbH Method and system for predicting gene expression perturbations
JPWO2024019081A1 (https=) 2022-07-22 2024-01-25
CN115798598B (zh) * 2022-11-16 2023-11-14 大连海事大学 一种基于超图的miRNA-疾病关联预测模型及方法
CN115861275B (zh) * 2022-12-26 2024-02-06 中南大学 细胞计数方法、装置、终端设备及介质
CN118072926B (zh) * 2024-04-17 2024-07-30 吉林大学 医疗机构院科两级感染风险评估系统及方法
CN118899037A (zh) * 2024-10-08 2024-11-05 福建医科大学附属第一医院 太空电离辐射关键分子的识别方法及系统

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US20050086035A1 (en) * 2003-09-02 2005-04-21 Pioneer Hi-Bred International, Inc. Computer systems and methods for genotype to phenotype mapping using molecular network models
US20070198653A1 (en) * 2005-12-30 2007-08-23 Kurt Jarnagin Systems and methods for remote computer-based analysis of user-provided chemogenomic data
US20090326897A1 (en) * 2006-07-11 2009-12-31 Bayer Technology Services Gmbh Method for determining the behavior of a biological system after a reversible perturbation
US20100216660A1 (en) * 2006-12-19 2010-08-26 Yuri Nikolsky Novel methods for functional analysis of high-throughput experimental data and gene groups identified therefrom

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US20070198653A1 (en) * 2005-12-30 2007-08-23 Kurt Jarnagin Systems and methods for remote computer-based analysis of user-provided chemogenomic data
US20090326897A1 (en) * 2006-07-11 2009-12-31 Bayer Technology Services Gmbh Method for determining the behavior of a biological system after a reversible perturbation
US20100216660A1 (en) * 2006-12-19 2010-08-26 Yuri Nikolsky Novel methods for functional analysis of high-throughput experimental data and gene groups identified therefrom

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Also Published As

Publication number Publication date
JP2014532205A (ja) 2014-12-04
CN107391961B (zh) 2020-11-17
JP2017073163A (ja) 2017-04-13
EP2754075A2 (en) 2014-07-16
US20140214336A1 (en) 2014-07-31
CN107391961A (zh) 2017-11-24
WO2013034300A3 (en) 2013-09-19
CN103782301A (zh) 2014-05-07
JP6138793B2 (ja) 2017-05-31
JP2018116729A (ja) 2018-07-26
WO2013034300A2 (en) 2013-03-14
JP6407242B2 (ja) 2018-10-17

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