CN103768041B - Method for preparing anaesthetic - Google Patents
Method for preparing anaesthetic Download PDFInfo
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- CN103768041B CN103768041B CN201410019275.XA CN201410019275A CN103768041B CN 103768041 B CN103768041 B CN 103768041B CN 201410019275 A CN201410019275 A CN 201410019275A CN 103768041 B CN103768041 B CN 103768041B
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- pipeline
- container body
- branch road
- pharmaceutical supply
- sealing
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Abstract
The invention provides a method for preparing anaesthetic. A preparation system is used in the method, and comprises a reaction container, a drug supply device, a gas stirring device and a pumping device, wherein the pumping device comprises a moving device driving a suction hose to move up and down. The method comprises the following steps: 1, supplying a first medicinal preparation; 2, stirring gas; 3, supplying a second medicinal preparation; 4, stirring gas; 5, moving the tail end of the hose close to the liquid surface by utilizing the moving device to pump residual emulsion.
Description
Technical field
The present invention relates to a kind of process for preparing medicine, is especially a kind of preparation method of anesthetics.
Background technology
The preparation process of anaesthetic owing to needing the various technological parameters adding various composition and control in preparation process, therefore more complicated comparatively speaking.At present, in order to realize the good guarantee of pharmaceutical properties, usual needs manually control state modulator in the interpolation weight of various medicine and process and drug treating.
The Ingredients Weight added is exceeded to the situation of ratio, such as, the composition of Emulsion often exceeds needs, and this is also the enough supplies in order to ensure to guarantee in preparation process Emulsion.But when processing preparation is complete, excessive Emulsion needs to remove.At this moment, in traditional method, need manually these excessive Emulsion to be removed.And the time that artificial removal needs is longer, and also there is relatively large deviation for the control of the amount removed.
Summary of the invention
In order to overcome above-mentioned defect, the present invention proposes a kind of preparation method of anesthetics, and it can realize machine supply of various composition, is convenient to control, and can carries out machine to excessive composition and remove, be convenient to the content accurately controlling various composition.Also can accurately control for the parameter in the course of processing simultaneously.
The technical solution used in the present invention is as follows:
A kind of preparation method of anesthetics, it use a kind of preparation system, described preparation system comprises prepares container, prepare container and there is the container body of bottom and the container neck on top, sealing-plug is provided with in container neck, first pipeline and the second pipeline are each passed through sealing-plug and reach in container body, wherein, first pipeline extend into the bottom of container body, second pipeline extend into the top of container body, the position that container body is inner relative is in the horizontal direction provided with two level detection sensors devices, the horizontal level of described two level detection sensors devices is consistent with the horizontal level that the second pipeline stretches into end, described two level detection sensors devices can sense itself and whether touch liquid level, first pipeline and sealing-plug are for being sealedly and fixedly connected, and the second pipeline and sealing-plug are for can mutually be connected by mobile sealing, and the second pipeline is also fixedly connected with the second pipeline mobile device above sealing-plug, and the second pipeline mobile device is fixedly connected with container neck, first pipeline is connected with the first exterior line, and the first exterior line is connected with the first second branch road with the first first branch road respectively, and the first first branch road is connected with the first pharmaceutical supply device by the first first valve, and the first second branch road is connected with first device by the first second valve, second pipeline is connected with the second second branch road with the second first branch road respectively by external hose, and the second first branch road is connected with the second pharmaceutical supply device by the second first valve, and the second second branch road is connected with the second device by the second second valve.
Second pipeline mobile device comprises fixing head, guide rail, screw rod and motor, wherein, fixing head is fixedly connected with the second pipeline, the screw coordinated with described screw rod is also fixedly installed in fixing head, guide rail is fixed on the medial wall of container neck, fixing head coordinates with slide, and motor is fixed on guide rail; Motor can, by the cooperation of screw rod and screw, make fixing head slide up and down along guide rail, thus drives the second pipeline to move up and down.
Wherein, the medicament of described first pharmaceutical supply device provisioning comprises glycerol, refining Oleum Glycines and water; The medicament of the second pharmaceutical supply device provisioning comprises liquid isoflurane; First device is gas stirring device, and the second device is aspirator.
The lower end of the second pipeline is provided with liquid level range sensor, for the distance of the lower end and liquid level of detecting the second pipeline; Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor and level detection sensors device, and sends control information respectively to described motor and respective valves.
Pumping liquid recovery port is also provided with in the bottom of described aspirator, described pumping liquid recovery port is connected with retracting device by reclaiming valve, when needing to reclaim the pumping liquid saved in described aspirator, to reclaim valve open, pumping liquid can be recycled in described retracting device and recycle.
The step of described method is as follows:
One, the first pharmaceutical supply device by pharmaceutical supply to container body;
Two, gas is passed into container body to stir medicament by first device;
Three, the second pharmaceutical supply device by pharmaceutical supply to container body;
Four, gas is passed into container body to stir medicament by first device;
Five, the end of the second pipeline is moved to medicament ullage by the second pipeline mobile device, and the second device starts, and is aspirated away by the unnecessary Emulsion that liquid level suspends.
Preferably, described liquid level range sensor is optical distance sensor or ultrasonic distance sensor.
Accompanying drawing explanation
Fig. 1 is the structural representation of preparation system of the present invention;
Fig. 2 is the structural representation of the second pipeline mobile device of the present invention.
Detailed description of the invention
A kind of preparation method of anesthetics, it use a kind of preparation system, described preparation system comprises prepares container, prepare container and there is the container body 1 of bottom and the container neck 11 on top, sealing-plug 18 is provided with in container neck 11, first pipeline 2 and the second pipeline 3 are each passed through sealing-plug 18 and reach in container body 1, wherein, first pipeline 2 extend into the bottom of container body 1, second pipeline 3 extend into the top of container body 1, the position that container body 1 inside is relative is in the horizontal direction provided with two level detection sensors devices 20, the horizontal level of described two level detection sensors devices 20 is consistent with the horizontal level that the second pipeline 3 stretches into end, described two level detection sensors devices 20 can sense itself and whether touch liquid level, first pipeline 2 and sealing-plug 18 are for being sealedly and fixedly connected, second pipeline 3 and sealing-plug 18 are for can mutually be connected by mobile sealing, second pipeline 3 is also fixedly connected with the second pipeline mobile device 6 above sealing-plug 18, and the second pipeline mobile device 6 is fixedly connected with container neck 11, first pipeline 2 is connected with the first exterior line 4, first exterior line 4 is connected with the first second branch road 16 with the first first branch road 26 respectively, first first branch road 26 is connected with the first pharmaceutical supply device 8 by the first first valve 13, and the first second branch road 16 is connected with first device 7 by the first second valve 12, second pipeline 3 is connected with the second second branch road 17 with the second first branch road 27 respectively by external hose 5, and the second first branch road 27 is connected with the second pharmaceutical supply device 9 by the second first valve 14, and the second second branch road 17 is connected with the second device 10 by the second second valve 15.
Second pipeline mobile device 6 comprises fixing head 64, guide rail 62, screw rod 63 and motor 61, wherein, fixing head 64 is fixedly connected with the second pipeline 3, the screw coordinated with described screw rod 63 is also fixedly installed in fixing head 64, guide rail 62 is fixed on the medial wall of container neck 11, fixing head 64 and guide rail 62 are slidably matched, and motor 61 is fixed on guide rail 62; Motor 61 can, by the cooperation of screw rod and screw, make fixing head 64 slide up and down along guide rail 62, thus drives the second pipeline 3 to move up and down.
Wherein, the medicament that described first pharmaceutical supply device 8 is supplied comprises glycerol, refining Oleum Glycines and water; The medicament that second pharmaceutical supply device 9 is supplied comprises liquid isoflurane; First device 7 is gas stirring device, and the second device 10 is aspirator.
The lower end of the second pipeline 3 is provided with liquid level range sensor 31, for the distance of the lower end and liquid level of detecting the second pipeline 3; Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor 31 and level detection sensors device 20, and sends control information respectively to described motor 61 and respective valves.
Pumping liquid recovery port is also provided with in the bottom of described aspirator, described pumping liquid recovery port is connected with retracting device 29 by reclaiming valve 19, when needing to reclaim the pumping liquid saved in described aspirator, opened by recovery valve 19, pumping liquid can be recycled in described retracting device 29 and recycle.
The step of described method is as follows:
One, the first pharmaceutical supply device 8 by pharmaceutical supply to container body 1;
Two, gas is passed into container body 1 to stir medicament by first device 7;
Three, the second pharmaceutical supply device 9 by pharmaceutical supply to container body 1;
Four, gas is passed into container body 1 to stir medicament by first device 7;
Five, the end of the second pipeline 3 is moved to medicament ullage by the second pipeline mobile device 6, and the second device 10 starts, and is aspirated away by the unnecessary Emulsion that liquid level suspends.
Preferably, described liquid level range sensor 31 is optical distance sensor or ultrasonic distance sensor.
Claims (2)
1. the preparation method of an anesthetics, it use a kind of preparation system, described preparation system comprises prepares container, it is characterized in that: prepare container and there is the container body (1) of bottom and the container neck (11) on top, sealing-plug (18) is provided with in container neck (11), first pipeline (2) and the second pipeline (3) are each passed through sealing-plug (18) and reach in container body (1), wherein, first pipeline (2) extend into the bottom of container body (1), second pipeline (3) extend into the top of container body (1), the position that container body (1) is inner relative is in the horizontal direction provided with two level detection sensors devices (20), the horizontal level of described two level detection sensors devices (20) is consistent with the horizontal level that the second pipeline (3) stretches into end, described two level detection sensors devices (20) can sense itself and whether touch liquid level, first pipeline (2) and sealing-plug (18) are for being sealedly and fixedly connected, second pipeline (3) and sealing-plug (18) are for can mutually be connected by mobile sealing, second pipeline (3) is also fixedly connected with the second pipeline mobile device (6) in sealing-plug (18) top, and the second pipeline mobile device (6) is fixedly connected with container neck (11), first pipeline (2) is connected with the first exterior line (4), first exterior line (4) is connected with the first second branch road (16) with the first first branch road (26) respectively, first first branch road (26) is connected with the first pharmaceutical supply device (8) by the first first valve (13), and the first second branch road (16) is connected with first device (7) by the first second valve (12), second pipeline (3) is connected with the second second branch road (17) with the second first branch road (27) respectively by external hose (5), second first branch road (27) is connected with the second pharmaceutical supply device (9) by the second first valve (14), and the second second branch road (17) is connected with the second device (10) by the second second valve (15),
Second pipeline mobile device (6) comprises fixing head (64), guide rail (62), screw rod (63) and motor (61), wherein, fixing head (64) is fixedly connected with the second pipeline (3), the screw coordinated with described screw rod (63) is also fixedly installed in fixing head (64), guide rail (62) is fixed on the medial wall of container neck (11), fixing head (64) and guide rail (62) are slidably matched, and motor (61) is fixed on guide rail (62); Motor (61) can, by the cooperation of screw rod and screw, make fixing head (64) slide up and down along guide rail (62), thus drives the second pipeline (3) to move up and down;
Wherein, the medicament that described first pharmaceutical supply device (8) is supplied comprises glycerol, refining Oleum Glycines and water; The medicament that second pharmaceutical supply device (9) is supplied comprises liquid isoflurane; First device (7) is gas stirring device, and the second device (10) is aspirator;
The lower end of the second pipeline (3) is provided with liquid level range sensor (31), for the distance of the lower end and liquid level of detecting the second pipeline (3); Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor (31) and level detection sensors device (20), and sends control information respectively to described motor (61) and respective valves;
Pumping liquid recovery port is also provided with in the bottom of described aspirator, described pumping liquid recovery port is connected with retracting device (29) by reclaiming valve (19), when needing to reclaim the pumping liquid saved in described aspirator, to reclaim valve (19) to open, pumping liquid can be recycled in described retracting device (29) and recycle;
The step of described method is as follows:
One, the first pharmaceutical supply device (8) by pharmaceutical supply to container body (1);
Two, gas is passed into container body (1) to stir medicament by first device (7);
Three, the second pharmaceutical supply device (9) by pharmaceutical supply to container body (1);
Four, gas is passed into container body (1) to stir medicament by first device (7);
Five, the end of the second pipeline (3) is moved to medicament ullage by the second pipeline mobile device (6), and the second device (10) starts, and is aspirated away by the unnecessary Emulsion that liquid level suspends.
2. the method for claim 1, wherein described liquid level range sensor (31) is optical distance sensor or ultrasonic distance sensor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410019275.XA CN103768041B (en) | 2014-01-16 | 2014-01-16 | Method for preparing anaesthetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410019275.XA CN103768041B (en) | 2014-01-16 | 2014-01-16 | Method for preparing anaesthetic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103768041A CN103768041A (en) | 2014-05-07 |
| CN103768041B true CN103768041B (en) | 2015-05-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410019275.XA Expired - Fee Related CN103768041B (en) | 2014-01-16 | 2014-01-16 | Method for preparing anaesthetic |
Country Status (1)
| Country | Link |
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| CN (1) | CN103768041B (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2039227U (en) * | 1988-11-23 | 1989-06-14 | 王茹兰 | Treatment equipment of emulsive waste liquid |
| US6371332B1 (en) * | 1999-07-13 | 2002-04-16 | Albert H. Fox | Apparatus for producing foam from liquid mixture |
| CN101683544B (en) * | 2008-09-28 | 2013-03-20 | 深圳迈瑞生物医疗电子股份有限公司 | Anesthesia evaporator |
| CN101569607B (en) * | 2009-06-16 | 2011-02-16 | 中国药科大学 | Di-demethoxycurcumin precursor liposome and preparation method thereof |
| CN101709263B (en) * | 2009-10-30 | 2012-07-18 | 南京工业大学 | Chemostat continuous cultivation device |
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2014
- 2014-01-16 CN CN201410019275.XA patent/CN103768041B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN103768041A (en) | 2014-05-07 |
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