CN103736421B - The system of band temperature-adjusting device and controller is used to prepare the method for arcotic - Google Patents
The system of band temperature-adjusting device and controller is used to prepare the method for arcotic Download PDFInfo
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- CN103736421B CN103736421B CN201310734731.4A CN201310734731A CN103736421B CN 103736421 B CN103736421 B CN 103736421B CN 201310734731 A CN201310734731 A CN 201310734731A CN 103736421 B CN103736421 B CN 103736421B
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Abstract
The invention provides a kind of method using the system of band temperature-adjusting device and controller to prepare arcotic, it use a kind of preparation system, described system comprises reaction vessel, pharmaceutical supply device, gas stirring device and aspirator, and described aspirator also comprises the mobile device that suction tube is moved up and down.Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor and level detection sensors device, and sends control information respectively to described motor and respective valves.The below of described container body is provided with temperature-adjusting device, for regulating the temperature in container.
Description
Technical field
The present invention relates to a kind of process for preparing medicine, is especially a kind of method using the system of band temperature-adjusting device and controller to prepare arcotic.
Background technology
The preparation process of anaesthetic owing to needing the various technological parameters adding various composition and control in preparation process, therefore more complicated comparatively speaking.At present, in order to realize the good guarantee of pharmaceutical properties, usual needs manually control state modulator in the interpolation weight of various medicine and process and drug-treated.
The Ingredients Weight added is exceeded to the situation of ratio, such as, the composition of emulsion often exceeds needs, and this is also the enough supplies in order to ensure to guarantee in preparation process emulsion.But when processing preparation is complete, excessive emulsion needs to remove.At this moment, in traditional method, need manually these excessive emulsion to be removed.And the time that artificial removal needs is longer, and also there is relatively large deviation for the control of the amount removed.
Summary of the invention
In order to overcome above-mentioned defect, the present invention proposes a kind of method using the system of band temperature-adjusting device and controller to prepare arcotic, and it can realize the machine supply of various composition, is convenient to control, and machine can be carried out to excessive composition to remove, be convenient to the content accurately controlling various composition.Also can accurately control for the parameter in process simultaneously.
The technical solution used in the present invention is as follows:
A kind of method using the system of band temperature-adjusting device and controller to prepare arcotic, it use a kind of preparation system, described preparation system comprises prepares container, prepare container and there is the container body of bottom and the container neck on top, sealing-plug is provided with in container neck, first pipeline and the second pipeline are each passed through sealing-plug and reach in container body, wherein, first pipeline extend into the bottom of container body, second pipeline extend into the top of container body, the position that container body is inner relative is in the horizontal direction provided with two level detection sensors devices, the horizontal level of described two level detection sensors devices is consistent with the horizontal level that the second pipeline stretches into end, described two level detection sensors devices can sense itself and whether touch liquid level, first pipeline and sealing-plug are for being sealedly and fixedly connected, and the second pipeline and sealing-plug are for can mutually be connected by mobile sealing, and the second pipeline is also fixedly connected with the second pipeline mobile device above sealing-plug, and the second pipeline mobile device is fixedly connected with container neck, first pipeline is connected with the first exterior line, and the first exterior line is connected with the first second branch road with the first first branch road respectively, and the first first branch road is connected with the first pharmaceutical supply device by the first first valve, and the first second branch road is connected with first device by the first second valve, second pipeline is connected with the second second branch road with the second first branch road respectively by external hose, and the second first branch road is connected with the second pharmaceutical supply device by the second first valve, and the second second branch road is connected with the second device by the second second valve.
Second pipeline mobile device comprises fixed head, guide rail, screw rod and motor, wherein, fixed head is fixedly connected with the second pipeline, the screw coordinated with described screw rod is also fixedly installed in fixed head, guide rail is fixed on the madial wall of container neck, fixed head coordinates with slide, and motor is fixed on guide rail; Motor can, by the cooperation of screw rod and screw, make fixed head slide up and down along guide rail, thus drives the second pipeline to move up and down.
Wherein, the medicament of described first pharmaceutical supply device provisioning comprises glycerine, refining soya-bean oil and water; The medicament of the second pharmaceutical supply device provisioning comprises liquid Isoflurane; First device is gas stirring device, and the second device is aspirator.
The lower end of the second pipeline is provided with liquid level range sensor, for the distance of the lower end and liquid level of detecting the second pipeline; Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor and level detection sensors device, and sends control information respectively to described motor and respective valves.
The below of described container body is provided with temperature-adjusting device, for regulating the temperature in container, containing liquid and electric heater in described temperature-adjusting device, electric heater can heat liquid off and on, thus liquid can be made to keep uniform temperature.
The step of described method is as follows:
One, the first pharmaceutical supply device by pharmaceutical supply to container body;
Two, gas is passed into container body to stir medicament by first device;
Three, the second pharmaceutical supply device by pharmaceutical supply to container body;
Four, gas is passed into container body to stir medicament by first device;
Five, the end of the second pipeline is moved to medicament ullage by the second pipeline mobile device, and the second device starts, and is aspirated away by the unnecessary emulsion that liquid level suspends.
Preferably, described liquid level range sensor is optical distance sensor or ultrasonic distance sensor.
By technique scheme, owing to have employed two kinds of medicine component feedwaies, achieve and the machine of these medicine components is supplied, can be convenient to realize accurate control; Meanwhile, Gas Stirring is utilized to control sufficient reacting; Utilize aspirator then to carry out machine to excessive emulsion to remove, carry out without the need to manual.Then aspirator can be realized good quantitative sucking-off corresponding to different liquid levels by moving up and down device, ensureing to avoid excessive suction while needing the amount of suction to aspirate.
Accompanying drawing explanation
Fig. 1 is the structural representation of preparation system of the present invention;
Fig. 2 is the structural representation of the second pipeline mobile device of the present invention.
Detailed description of the invention
A kind of method using the system of band temperature-adjusting device and controller to prepare arcotic, it use a kind of preparation system, described preparation system comprises prepares container, prepare container and there is the container body 1 of bottom and the container neck 11 on top, sealing-plug 18 is provided with in container neck 11, first pipeline 2 and the second pipeline 3 are each passed through sealing-plug 18 and reach in container body 1, wherein, first pipeline 2 extend into the bottom of container body 1, second pipeline 3 extend into the top of container body 1, the position that container body 1 inside is relative is in the horizontal direction provided with two level detection sensors devices 20, the horizontal level of described two level detection sensors devices 20 is consistent with the horizontal level that the second pipeline 3 stretches into end, described two level detection sensors devices 20 can sense itself and whether touch liquid level, first pipeline 2 and sealing-plug 18 are for being sealedly and fixedly connected, second pipeline 3 and sealing-plug 18 are for can mutually be connected by mobile sealing, second pipeline 3 is also fixedly connected with the second pipeline mobile device 6 above sealing-plug 18, and the second pipeline mobile device 6 is fixedly connected with container neck 11, first pipeline 2 is connected with the first exterior line 4, first exterior line 4 is connected with the first second branch road 16 with the first first branch road 26 respectively, first first branch road 26 is connected with the first pharmaceutical supply device 8 by the first first valve 13, and the first second branch road 16 is connected with first device 7 by the first second valve 12, second pipeline 3 is connected with the second second branch road 17 with the second first branch road 27 respectively by external hose 5, and the second first branch road 27 is connected with the second pharmaceutical supply device 9 by the second first valve 14, and the second second branch road 17 is connected with the second device 10 by the second second valve 15.
Second pipeline mobile device 6 comprises fixed head 64, guide rail 62, screw rod 63 and motor 61, wherein, fixed head 64 is fixedly connected with the second pipeline 3, the screw coordinated with described screw rod 63 is also fixedly installed in fixed head 64, guide rail 62 is fixed on the madial wall of container neck 11, fixed head 64 and guide rail 62 are slidably matched, and motor 61 is fixed on guide rail 62; Motor 61 can, by the cooperation of screw rod and screw, make fixed head 64 slide up and down along guide rail 62, thus drives the second pipeline 3 to move up and down.
Wherein, the medicament that described first pharmaceutical supply device 8 is supplied comprises glycerine, refining soya-bean oil and water; The medicament that second pharmaceutical supply device 9 is supplied comprises liquid Isoflurane; First device 7 is gas stirring device, and the second device 10 is aspirator.
The lower end of the second pipeline 3 is provided with liquid level range sensor 31, for the distance of the lower end and liquid level of detecting the second pipeline 3; Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor 31 and level detection sensors device 20, and sends control information respectively to described motor 61 and respective valves.
The below of described container body 1 is provided with temperature-adjusting device 19, for regulating the temperature in container 1, containing liquid and electric heater 91 in described temperature-adjusting device 19, electric heater 91 can heat liquid off and on, thus liquid can be made to keep uniform temperature.
The step of described method is as follows:
One, the first pharmaceutical supply device 8 by pharmaceutical supply to container body 1;
Two, gas is passed into container body 1 to stir medicament by first device 7;
Three, the second pharmaceutical supply device 9 by pharmaceutical supply to container body 1;
Four, gas is passed into container body 1 to stir medicament by first device 7;
Five, the end of the second pipeline 3 is moved to medicament ullage by the second pipeline mobile device 6, and the second device 10 starts, and is aspirated away by the unnecessary emulsion that liquid level suspends.
Preferably, described liquid level range sensor 31 is optical distance sensor or ultrasonic distance sensor.
Claims (2)
1. the method using the system of band temperature-adjusting device and controller to prepare arcotic, it use a kind of preparation system, described preparation system comprises prepares container, it is characterized in that: prepare container and there is the container body (1) of bottom and the container neck (11) on top, sealing-plug (18) is provided with in container neck (11), first pipeline (2) and the second pipeline (3) are each passed through sealing-plug (18) and reach in container body (1), wherein, first pipeline (2) extend into the bottom of container body (1), second pipeline (3) extend into the top of container body (1), the position that container body (1) is inner relative is in the horizontal direction provided with two level detection sensors devices (20), the horizontal level of described two level detection sensors devices (20) is consistent with the horizontal level that the second pipeline (3) stretches into end, described two level detection sensors devices (20) can sense itself and whether touch liquid level, first pipeline (2) and sealing-plug (18) are for being sealedly and fixedly connected, second pipeline (3) and sealing-plug (18) are for can mutually be connected by mobile sealing, second pipeline (3) is also fixedly connected with the second pipeline mobile device (6) in sealing-plug (18) top, and the second pipeline mobile device (6) is fixedly connected with container neck (11), first pipeline (2) is connected with the first exterior line (4), first exterior line (4) is connected with the first second branch road (16) with the first first branch road (26) respectively, first first branch road (26) is connected with the first pharmaceutical supply device (8) by the first first valve (13), and the first second branch road (16) is connected with first device (7) by the first second valve (12), second pipeline (3) is connected with the second second branch road (17) with the second first branch road (27) respectively by external hose (5), second first branch road (27) is connected with the second pharmaceutical supply device (9) by the second first valve (14), and the second second branch road (17) is connected with the second device (10) by the second second valve (15),
Second pipeline mobile device (6) comprises fixed head (64), guide rail (62), screw rod (63) and motor (61), wherein, fixed head (64) is fixedly connected with the second pipeline (3), the screw coordinated with described screw rod (63) is also fixedly installed in fixed head (64), guide rail (62) is fixed on the madial wall of container neck (11), fixed head (64) and guide rail (62) are slidably matched, and motor (61) is fixed on guide rail (62); Motor (61) can, by the cooperation of screw rod and screw, make fixed head (64) slide up and down along guide rail (62), thus drives the second pipeline (3) to move up and down;
Wherein, the medicament that described first pharmaceutical supply device (8) is supplied comprises glycerine, refining soya-bean oil and water; The medicament that second pharmaceutical supply device (9) is supplied comprises liquid Isoflurane; First device (7) is gas stirring device, and the second device (10) is aspirator;
The lower end of the second pipeline (3) is provided with liquid level range sensor (31), for the distance of the lower end and liquid level of detecting the second pipeline (3); Described preparation system also comprises controller, and described controller is used for the information of receiving liquid face range sensor (31) and level detection sensors device (20), and sends control information respectively to described motor (61) and respective valves;
The below of described container body (1) is provided with temperature-adjusting device (19), for regulating the temperature in container (1), containing liquid and electric heater (91) in described temperature-adjusting device (19), electric heater (91) can heat liquid off and on, thus liquid can be made to keep uniform temperature;
The step of described method is as follows:
One, the first pharmaceutical supply device (8) by pharmaceutical supply to container body (1);
Two, gas is passed into container body (1) to stir medicament by first device (7);
Three, the second pharmaceutical supply device (9) by pharmaceutical supply to container body (1);
Four, gas is passed into container body (1) to stir medicament by first device (7);
Five, the end of the second pipeline (3) is moved to medicament ullage by the second pipeline mobile device (6), and the second device (10) starts, and is aspirated away by the unnecessary emulsion that liquid level suspends.
2. the method for claim 1, wherein described liquid level range sensor (31) is optical distance sensor or ultrasonic distance sensor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310734731.4A CN103736421B (en) | 2013-12-27 | 2013-12-27 | The system of band temperature-adjusting device and controller is used to prepare the method for arcotic |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310734731.4A CN103736421B (en) | 2013-12-27 | 2013-12-27 | The system of band temperature-adjusting device and controller is used to prepare the method for arcotic |
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| Publication Number | Publication Date |
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| CN103736421A CN103736421A (en) | 2014-04-23 |
| CN103736421B true CN103736421B (en) | 2015-09-02 |
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| CN201310734731.4A Expired - Fee Related CN103736421B (en) | 2013-12-27 | 2013-12-27 | The system of band temperature-adjusting device and controller is used to prepare the method for arcotic |
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| CN104772095B (en) * | 2015-03-16 | 2016-05-18 | 浙江大学 | Automatically regulate chloramines preparation facilities and the method thereof of pharmacy response usage ratio according to variations in temperature |
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| DE4228776A1 (en) * | 1992-08-28 | 1994-03-03 | Bosch Siemens Hausgeraete | Device for enriching water with CO¶2¶ gas to produce carbonated water |
| US6260477B1 (en) * | 1999-10-25 | 2001-07-17 | Automatic Bar Controls, Inc. | Autofill system with improved automixing |
| CN201676667U (en) * | 2010-04-22 | 2010-12-22 | 苏州天成燃气设备技术开发有限公司 | Proportioned gas-liquid blending system employing accurate pressure control |
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