CN103753818A - Micro sprinkler for manufacturing three-dimensional micro-nano fiber bracket - Google Patents
Micro sprinkler for manufacturing three-dimensional micro-nano fiber bracket Download PDFInfo
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- CN103753818A CN103753818A CN201410025693.XA CN201410025693A CN103753818A CN 103753818 A CN103753818 A CN 103753818A CN 201410025693 A CN201410025693 A CN 201410025693A CN 103753818 A CN103753818 A CN 103753818A
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Abstract
The invention provides a micro sprinkler for manufacturing a three-dimensional micro-nano fiber bracket. A screw bracket is arranged in the middle of a fixed plate; one end of a ball screw is connected with an output end of a stepper motor; a ball screw nut and the ball screw form a ball screw pair; a loading platform is connected with the ball screw nut; a spray head is arranged on a spray head support frame; one end of an extrusion push rod is connected with the loading platform; the other end of the extrusion push rod is connected with a piston inside the spray head; a nozzle is arranged at the front end of the spray head; a heat insulation device is arranged on the spray head. The nut and the screw rod in a ball screw nut mechanism disclosed by the invention are in rolling friction, so that the creeping phenomenon is not generated in the speed range of practical application; the temperature control process of the slurry before being extruded can be further refined according to the experiment requirements; a bipolar temperature control process is achieved. By adopting the process, a processing bracket tissue structure can be refined, and the process has an important role in processing of a tissue engineering bracket with a nano fiber.
Description
Technical field
The present invention relates to a kind of mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework, belong to tissue engineering technique field.
Background technology
Organizational project is a cross discipline that combines the subjects such as cell biology, engineering science, material science and medical science surgery, organizational project is intended to application project and life science principle, and exploitation is for recovering, maintain and improve the biology substitute of damaged tissue and organ dysfunction.Tissue engineering bracket is one of core carrier key element of biomedical tissue engineering, and the preparation of tissue engineering bracket refers to is processed into needed form by biomaterial.After 20th century, the mid-80 proposed the concept of organizational project, the manufacturing technology of organization bracket is able to development.It is as the implant of organizational project, need to guarantee that living cells can progressively grow into wherein after carrier bracket implants.For this reason, the support that need to manufacture multistage micro nano structure is to guarantee that cell survives and grows in-house.
The forming technology of tissue engineering bracket comprises fiber connection method, solution-cast pore-foaming agent method, thermally induced phase separation, fusing molding etc.In addition the forming technology of tissue engineering bracket melts molding, freeze-drying, fiber-reinforced method, melting die pressing, air pressure port-creating method etc. in addition.Above-mentioned these traditional handicrafts all can not realize the figuration manufacture of complicated heterogeneous material support, can not realize the control accurately flexibly to micro-nano hole gap structure, can not realize personalized implant manufacture.Therefore, need to find the method that can precision form produces the controlled tissue engineering bracket of micro-structural.
Quick-forming (Rapid Prototyping is called for short RP) technology is the manufacturing new and high technology that is applied to occurring for 1987.It adopts the concept finished parts of discrete/accumulation, can manufacture the 3D solid of any complicated shape, and not need special mould, instrument or artificial interference, has the flexibility of height.The forming process of rapid shaping technique is: first utilize CAD Software for Design to go out the CAD electronic model of part, then according to concrete technology requirement, press certain thickness layering (normally along Z direction), by its discrete be a series of two-dimentional aspects, be referred to as traditionally layering or section (Slicing), again these discrete messages are combined with machined parameters, generate NC code and input to forming machine.Forming machine is according to NC code, and order is processed each cell cube and is bonded to each other, thereby obtains the 3D solid corresponding with model (being called again physical model or prototype).By departure process, complicated three-dimensional manufacture is changed into a series of orderly manufacture of simple cell cube and the processes of combination, thereby in principle, can complete the geometrical body of any complex topology relation, be not subject to the restriction of part complexity.Above-mentioned manufacturing process is (X, Y, Z all can adopt simple rectilinear motion) except the three-dimension numerical controlled motion of the molding machine by setting, biologic bracket material is mainly to spray from mini sprinkler, and be progressively injected on each layer lamination, thereby can obtain highly consistent micro nano structure tissue, and that this point is also manufactured personalized human organ is just necessary.The highly flexible of Quick-forming and rapidity can meet the demand of tissue engineering bracket individual character manufacturing, have the incomparable advantage of traditional tissue engineering bracket, are widely applied.
Summary of the invention
The object of the invention is to carry out the architecture advances of mini sprinkler on traditional sprinkler heads basis, a kind of mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework is provided, make this mini sprinkler by control motor can adjust material spray amount number and material spray speed, realize tissue engineering bracket stable, fast, moulding manufacture that macrovoid is adjustable, can produce the micro-nano-scale cavity support that is applicable to different kind organism Growth of Cells by fast and flexible, realize the manufacture of personalized implant support.
The object of the invention is to be achieved through the following technical solutions:
A kind of mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework: comprise stepper motor, ball-screw, fixed head, ball-screw nut, weighted platform, leading screw support, pressure-ram, shower nozzle, shower nozzle bracing frame, heating and heat-insulating device one and nozzle, it is characterized in that, described stepper motor is arranged on the side on fixed head, shower nozzle bracing frame is arranged on the opposite side on fixed head, leading screw support is arranged on the middle part on fixed head, ball-screw is arranged on leading screw support, one end of ball-screw is connected with the output of stepper motor, ball-screw nut and ball-screw form ball screw assembly, weighted platform is connected with ball-screw nut, shower nozzle is arranged on shower nozzle bracing frame, one end of pressure-ram is connected with weighted platform, the other end of pressure-ram is connected with the piston in shower nozzle, the front end of shower nozzle is provided with nozzle, heating and heat-insulating device one is arranged on shower nozzle.
Also comprise heating and heat-insulating device two, described heating and heat-insulating device two is arranged on the shower nozzle at heating and heat-insulating device one rear portion.
The present invention compared with prior art its technique effect is: the first, improve the scope that shower nozzle can expand quick forming materials machining materials.The feeding principle of traditional sprinkler heads is dead-weight feeding, when the viscosity of slurry is larger, can cause feeding not enough.Shower nozzle after the present invention improves is directly to push feeding, and the material spray process of the course of conveying of slurry and shower nozzle is carried out simultaneously, and therefore no matter the viscosity of material is large or little, only needs the rotating speed of control step motor, just can control the speed of shower nozzle material spray.The second, ball-screw nut mechanism is comparatively accurate, because often the spray silk of the shower nozzle required straight-line speed of moving is less, common feed screw nut, in slow motion process, has creeping phenomenon.In ball-screw nut mechanism in the present invention, nut and leading screw are rolling friction, therefore in the velocity interval of practice without the appearance of creeping phenomenon.And the shower nozzle after improving, experimental requirement, the further temperature control process of refined pulp before extruding.Realize the process of bipolar temperature control, this process can refinement machining support institutional framework, and the tissue engineering bracket to processing with nanofiber has important effect.
Accompanying drawing explanation
Fig. 1 is the mini sprinkler fundamental diagram that the present invention manufactures for three-D micro-nano rice fibrous framework;
Fig. 2 is mini sprinkler structural representation;
Fig. 3 is the mini sprinkler structural representation that the present invention manufactures for three-D micro-nano rice fibrous framework.
The specific embodiment
As shown in Fig. 1 ~ Fig. 3, this specific embodiment provides a kind of mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework, comprise stepper motor 1, ball-screw 2, fixed head 3, ball-screw nut 5, weighted platform 6, leading screw support 7, pressure-ram 8, shower nozzle 9, shower nozzle bracing frame 10, heating and heat-insulating device 1, heating and heat-insulating device 2 12 and nozzle 13, described stepper motor 1 is arranged on the side on fixed head 3, shower nozzle bracing frame 10 is arranged on the opposite side on fixed head 3, leading screw support 7 is arranged on the middle part on fixed head 3, ball-screw 2 is arranged on leading screw support 7, one end of ball-screw 2 is connected with the output of stepper motor 1, ball-screw nut 5 forms ball screw assembly, with ball-screw 2, weighted platform 6 is connected with ball-screw nut 5, shower nozzle 9 is arranged on shower nozzle bracing frame 10, one end of pressure-ram 8 is connected with weighted platform 6, the other end of pressure-ram 8 is connected with the piston 8-1 in shower nozzle 9, the front end of shower nozzle 9 is provided with nozzle 13, heating and heat-insulating device 1 is arranged on shower nozzle 9.
Further, also comprise heating and heat-insulating device 2 12, described heating and heat-insulating device 2 12 is arranged on the shower nozzle 9 at heating and heat-insulating device one 11 rear portions.
Heater in described heating and heat-insulating device 1 or heating and heat-insulating device 2 12 is resistance heater, and power is 100w.
Operation principle:
By ball-screw nut mechanism, the circumferencial direction of stepper motor is rotatablely moved, be converted into the rectilinear motion of ball-screw nut along continuous straight runs, by the rectilinear motion of weighted platform, directly the slurry of extruding jet inside, goes out slurry from shower nozzle internal spray.The speed of extruding slurry can realize by the rotating speed of computer-controlled stepper motor; The temperature that slurry is extruded can be by realizing the control of shower nozzle internal temperature.
Ball-screw and ball-screw nut have formed ball screw assembly,, stepper motor is connected with ball-screw, ball-screw nut 5 is connected with weighted platform, when the stepper motor being connected with ball screw framework drives ball-screw precision rotation, produce accurate translational motion with nut and the weighted platform of ball-screw precision-fit, drive pressure-ram, make slurry in shower nozzle from nozzle ejection out.Ball-screw and shower nozzle are fixed together by leading screw support, shower nozzle bracing frame and fixed head.
Described weighted platform is a linear rolling track, compares coefficient of friction less (0.0003-0.0005) with identical rail plate, therefore for motion in the situation of the little displacement of straight line low speed flexibly, non-slip, kinematic accuracy is high, and positioning precision is also high can reach 0.1 μ m-0.2 μ m.Simultaneously after pretension, good rigidity, the life-span is long.According to shower nozzle service condition and required precision, select the LM guide rail SRS of THK serial, model is SRS12M UU+120L M, and through load and capacity are checked, this guide rail meets the demands.
Ball screw assembly, axial rigidity is higher, motion steadily, transmission efficiency is high, transmission accuracy is high, not easy to wear, long service life, low speed are difficult for creeping.Consider service condition of the present invention, selecting helical pitch is the THKBNK0801 standard lead precise ball screw rod of 1mm.Then according to selecting BNK0801-3GT+145LC5Y M leading screw in the situation of the global design load of whole shower nozzle and life requirements.Because stroke is short, movement velocity is low, this ball-screw adopts the supporting way that one end is fixed, move about in one end, can reduce the impact that screw mandrel thermal deformation brings, and keeps higher positioning precision.
During extruding, consider to take slurry convenient, what pressure-ram adopted is disposable medical syringe.This syringe cost is low, and can directly from wide-mouth bottle, draw slurry., there is heating and heat-insulating device outside at syringe.Wherein heater is resistance heater, and power is 100w.The temperature sensor of attemperating unit adopts thermocouple assembly.The PXW-4 temp controlled meter that attemperating unit core adopts Japanese FUJI company to produce.Temp controlled meter is according to detecting in real time the operation that the temperature value obtaining is controlled heating component.
In the time of the bipolar temperature control of needs, can at shower nozzle place, add again a heating and heat-insulating device according to concrete structure, can realize the bipolar temperature control of slurry before extruding.On the basis of single-stage temperature control, only need add a heating and heat-insulating device just can reach bipolar temperature controlled requirement.
Claims (3)
1. a mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework, comprise stepper motor (1), ball-screw (2), fixed head (3), ball-screw nut (5), weighted platform (6), leading screw support (7), pressure-ram (8), shower nozzle (9), shower nozzle bracing frame (10), heating and heat-insulating device one (11) and nozzle (13), it is characterized in that, described stepper motor (1) is arranged on the side on fixed head (3), shower nozzle bracing frame (10) is arranged on the opposite side on fixed head (3), leading screw support (7) is arranged on the middle part on fixed head (3), ball-screw (2) is arranged on leading screw support (7), one end of ball-screw (2) is connected with the output of stepper motor (1), ball-screw nut (5) forms ball screw assembly, with ball-screw (2), weighted platform (6) is connected with ball-screw nut (5), shower nozzle (9) is arranged on shower nozzle bracing frame (10), one end of pressure-ram (8) is connected with weighted platform (6), the other end of pressure-ram (8) is connected with the piston (8-1) in shower nozzle (9), the front end of shower nozzle (9) is provided with nozzle (13), heating and heat-insulating device one (11) is arranged on shower nozzle (9).
2. a kind of mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework according to claim 1, it is characterized in that, also comprise heating and heat-insulating device two (12), described heating and heat-insulating device two (12) is arranged on the shower nozzle (9) at heating and heat-insulating device one (11) rear portion.
3. a kind of mini sprinkler of manufacturing for three-D micro-nano rice fibrous framework according to claim 2, is characterized in that, the heater in described heating and heat-insulating device one (11) or heating and heat-insulating device two (12) is resistance heater, and power is 100w.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410025693.XA CN103753818A (en) | 2014-01-21 | 2014-01-21 | Micro sprinkler for manufacturing three-dimensional micro-nano fiber bracket |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410025693.XA CN103753818A (en) | 2014-01-21 | 2014-01-21 | Micro sprinkler for manufacturing three-dimensional micro-nano fiber bracket |
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| CN103753818A true CN103753818A (en) | 2014-04-30 |
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| CN201410025693.XA Pending CN103753818A (en) | 2014-01-21 | 2014-01-21 | Micro sprinkler for manufacturing three-dimensional micro-nano fiber bracket |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105057667A (en) * | 2015-09-02 | 2015-11-18 | 华中科技大学 | 3D printing mechanism |
| CN105150538A (en) * | 2015-09-22 | 2015-12-16 | 重庆塞拉雷利科技有限公司 | 3D printer for fluid materials |
| CN105584046A (en) * | 2015-12-29 | 2016-05-18 | 中国石油大学(北京) | 3D printer and 3D printing method |
| CN105881887A (en) * | 2014-12-29 | 2016-08-24 | 无锡龙舜实业有限公司 | Welding machine for water distribution pipes |
| CN105880889A (en) * | 2014-12-29 | 2016-08-24 | 无锡龙舜实业有限公司 | Vertical welding machine for water distribution pipes |
| CN106515003A (en) * | 2016-12-16 | 2017-03-22 | 中国地质大学（武汉） | Jet type 3D print head and printer using jet type 3D print head |
| CN108819219A (en) * | 2018-09-07 | 2018-11-16 | 上海黑焰医疗科技有限公司 | A kind of hand-held 3D biomaterial extruder |
| CN110328852A (en) * | 2019-06-27 | 2019-10-15 | 陕西科技大学 | A kind of the 3D printing equipment and its application method of continuous fiber reinforcement silicon rubber |
| CN112248437A (en) * | 2020-09-02 | 2021-01-22 | 清华大学 | Silicone rubber liquid 3D printing feeding and extruding device and 3D printing equipment |
| CN116353047A (en) * | 2023-04-11 | 2023-06-30 | 哈尔滨工业大学 | Biological 3D prints crowded silk module with dual drive |
-
2014
- 2014-01-21 CN CN201410025693.XA patent/CN103753818A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| LIANG YINGCHUN等: "3D PLLA/Nano-hydroxyapatite Scaffolds with Hierarchical Porous Structure Fabricated by Lowtemperature Deposition Manufacturing", 《JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATER. SCI. ED.》 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105881887A (en) * | 2014-12-29 | 2016-08-24 | 无锡龙舜实业有限公司 | Welding machine for water distribution pipes |
| CN105880889A (en) * | 2014-12-29 | 2016-08-24 | 无锡龙舜实业有限公司 | Vertical welding machine for water distribution pipes |
| CN105057667A (en) * | 2015-09-02 | 2015-11-18 | 华中科技大学 | 3D printing mechanism |
| CN105150538A (en) * | 2015-09-22 | 2015-12-16 | 重庆塞拉雷利科技有限公司 | 3D printer for fluid materials |
| CN105584046A (en) * | 2015-12-29 | 2016-05-18 | 中国石油大学(北京) | 3D printer and 3D printing method |
| CN106515003A (en) * | 2016-12-16 | 2017-03-22 | 中国地质大学（武汉） | Jet type 3D print head and printer using jet type 3D print head |
| CN108819219A (en) * | 2018-09-07 | 2018-11-16 | 上海黑焰医疗科技有限公司 | A kind of hand-held 3D biomaterial extruder |
| CN110328852A (en) * | 2019-06-27 | 2019-10-15 | 陕西科技大学 | A kind of the 3D printing equipment and its application method of continuous fiber reinforcement silicon rubber |
| CN112248437A (en) * | 2020-09-02 | 2021-01-22 | 清华大学 | Silicone rubber liquid 3D printing feeding and extruding device and 3D printing equipment |
| CN112248437B (en) * | 2020-09-02 | 2021-11-23 | 清华大学 | Silicone rubber liquid 3D printing feeding and extruding device and 3D printing equipment |
| CN116353047A (en) * | 2023-04-11 | 2023-06-30 | 哈尔滨工业大学 | Biological 3D prints crowded silk module with dual drive |
| CN116353047B (en) * | 2023-04-11 | 2024-02-06 | 哈尔滨工业大学 | Biological 3D prints crowded silk module with dual drive |
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Application publication date: 20140430 |