CN103751745B

CN103751745B - A kind of Traditional Chinese drug mixture treating urticaria

Info

Publication number: CN103751745B
Application number: CN201410012176.9A
Authority: CN
Inventors: 周兰柱; 许伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-01-13
Filing date: 2014-01-13
Publication date: 2016-06-15
Anticipated expiration: 2034-01-13
Also published as: CN103751745A

Abstract

The present invention provides a kind of Traditional Chinese drug mixture treating urticaria, it is characterised in that be made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 10-30 part, Radix Curcumae 5-15 part, Cortex Moutan 5-15 part, Semen Persicae 5-15 part, Radix Scutellariae 5-15 part, Radix Codonopsis 5-15 part, Rhizoma Pinelliae 5-15 part, Rhizoma Zingiberis Recens 1-5 part, Radix Glycyrrhizae Preparata 5-15 part, Fructus Jujubae 5-15 part, Herba Ephedrae 3-8 part, Herba Asari 3-8 part. It is obvious that the present invention has curative effect for treatment urticaria, and treatment cost is low, it does not have the advantages such as side effect.

Description

A kind of Traditional Chinese drug mixture treating urticaria

Technical field:

The present invention relates to technical field of Chinese medicines, specifically a kind of Traditional Chinese drug mixture treating urticaria.

Background technology:

Urticaria is a kind of common dermatosis. It it is the multiple different mucocutaneous vascular reactivity disease of one caused by reason. Showing as flickering, well-defined, red or white pruritic welt, the traditional Chinese medical science claims " urticaria ", is commonly called as " rubella wheal ". The course of disease of rubella wheal is indefinite, and what have erythra for several times occurred within one day, stops outbreak, be called acute urticaria after a few days or 1～2 thoughtful several weeks. There is erythra in many patients, or occur time and again by spells or increase the weight of, alleviate or disappear everyday, as long as several months or several years, is called chronic urticaria and specific type urticaria.

The treatment of urticaria is mainly used the medicines such as chlorphenamine, Decloxizine, loratadine and excellent pool to treat by current doctor trained in Western medicine, but often makes patient produce the problems such as side effect generation such as drowsiness, dizzy, xerostomia. And use existing Chinese medicinal formulae usually therapeutic effect poor, and the drug withdrawal easily problem such as repeatedly.

Summary of the invention:

The present invention is to solve the deficiency to urticaria treatment in prior art, it is provided that it is obvious that a kind for the treatment of for urticaria has curative effect, and treatment cost is low, it does not have the Traditional Chinese drug mixture of side effect.

The following is technical scheme provided by the invention:

A kind of Traditional Chinese drug mixture treating urticaria, it is characterised in that be made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 10-30 part, Radix Curcumae 5-15 part, Cortex Moutan 5-15 part, Semen Persicae 5-15 part, Radix Scutellariae 5-15 part, Radix Codonopsis 5-15 part, Rhizoma Pinelliae 5-15 part, Rhizoma Zingiberis Recens 1-5 part, Radix Glycyrrhizae Preparata 5-15 part, Fructus Jujubae 5-15 part, Herba Ephedrae 3-8 part, Herba Asari 3-8 part.

Optimization formula is:

Radix Bupleuri 15 parts, Radix Curcumae 10 parts, Cortex Moutan 10 parts, 10 parts of Semen Persicae, Radix Scutellariae 10 parts, Radix Codonopsis 10 parts, the Rhizoma Pinelliae 10 parts, 3 parts of Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata 10 parts, Fructus Jujubae 10 parts, 6 parts of Herba Ephedrae, Herba Asari 6 parts.

Below to making the pharmacology of various raw material of Chinese medicine of the present invention, drug effect is described further:

Radix Bupleuri: bitter in the mouth, pungent, cold nature. Return Liver Channel, gallbladder meridian. There is expelling pathogenic factors from the exterior expel the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, rise effects such as lifting yang-energy. In this product, contained Bupleurum chinense polysaccharide can improve the phagocytic function of cell, make Natural killer activity strengthen, and improves special viral antibody titre, improves lymphocyte and turns core rate, improves skin delayed hypersensitivity reaction.

Radix Curcumae: acrid in the mouth, hardship, cold in nature. Return liver, the heart, lung meridian. Have regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire the effects such as removing heat from blood. The water logging agent of this product, in vitro all has inhibitory action in various degree to trichophyton, Trichophyton concentricunm, trichophyton gypseum, perhaps blue achorion, Du's dermatophytes such as big belly microspore tinea bacterium, rust microspore tinea bacterium difficult to understand.

Cortex Moutan: bitter in the mouth, pungent, cold nature.GUIXIN, liver, kidney channel. There is clearing away heat and cooling blood; The effects such as promoting blood circulation to remove blood stasis. Bacillus subtilis, escherichia coli, Bacillus typhi, Salmonella paratyphi, Bacillus proteus, bacillus pyocyaneus, staphylococcus, Hemolytic streptococcus, streptococcus pneumoniae, vibrio cholera etc. are all had stronger antibacterial action by Cortex Moutan decoct by the decoct of this product, and dysentery bacterium, bacillus pyocyaneus and staphylococcus aureus are had notable antibacterial action by leaf of paeonia suffruticosa ardr. decoct. Contained paeonol also has the effects such as antiinflammatory, analgesia, calmness, antipyretic, diuresis.

Semen Persicae: taste bitter, sweet, flat. GUIXIN, liver, large intestine channel. There is blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma. The water decoction of this product and extract have analgesia, antiinflammatory, antibacterial, anti-allergic effects.

Radix Scutellariae: bitter in the mouth, cold nature. Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian. There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive. The effects such as this product also has antiplatelet aggregation and anticoagulant, blood fat reducing, protects the liver, function of gallbladder promoting, antioxidation.

Radix Codonopsis: sweet in the mouth, micro-acid, property is put down. Return spleen, lung meridian. There is invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting. This product has enhancing human body immunity function, strengthens hemopoietic function, anti-stress, heart tonifying, shock, adjustment blood pressure, resists myocardial ischemia and suppresses the effects such as platelet aggregation. Also there is the effects such as Fructus Alpiniae Oxyphyllae, calmness, hypnosis, convulsion.

The Rhizoma Pinelliae: acrid in the mouth, warm in nature. Return lung, spleen, stomach warp. There is the effects such as drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, reducing swelling and alleviating pain. This product also has the effects such as antiulcer, blood fat reducing, tranquilizing soporific, antitumor, removing toxic substances antiinflammatory.

Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature. Return lung, spleen channel. There is relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, effect of warming the lung to relieve cough. Research shows: this product has gone out to be had, antiinflammatory, protect the liver, outside the effect such as function of gallbladder promoting, antioxidation, its contained shogaol also has excited vasomotor center, respiratory center and action of the heart.

Radix Glycyrrhizae Preparata: sweet in the mouth, property is put down. Enter spleen, stomach, lung meridian. There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription. This product also has antiinflammatory, antiviral and the function such as protecting liver and detoxication and enhancing immunity, anti-cancer and cancer-preventing, interferon inducer and cell immunomodulator.

Fructus Jujubae: sweet in the mouth, warm in nature, return spleen, stomach warp. There is invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relax effect of the property of medicine. Research shows: this product also has, and prevents transfusion reaction, reduces serum glutamic pyruvic transminase, antitumor, antioxidation, blood pressure lowering, cholesterol reducing, hepatoprotective, improves immunity, preventing and treating cerebral blood supply insufficiency, antiallergic, anti-angiocardiopathy, prevent and treat the effect such as osteoporosis and anemia.

Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature. Return lung, bladder warp. Have and relieving asthma, antitussive, remove expectorant, diaphoresis, diuresis, antiinflammatory, antipyretic, effect of excited maincenter. This product also has the effect such as antiinflammatory, antibacterial, antiviral.

Herba Asari: acrid in the mouth, warm in nature. Return lung, kidney, heart channel. There is expelling wind and cold, sensible pain relieving, effect of warming the lung to resolve fluid-retention. This product volatile oil, decoct and ethanol extract have the effects such as analgesia, antipyretic, antibacterial, antiinflammatory, antitussive, antihistaminic, enhancing cortex metabolism, antiallergic action and local anaesthesia.

All medicine compatibilities of the present invention, bring out the best in each other, have expelling pathogenic factors from the exterior and expel the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, dissolving lump and resolving mass, invigorating the spleen and replenishing QI, it is suppressed that the effects such as fungus, each drug effect has synergism, treatment for urticaria has evident in efficacy, treating both the principal and secondary aspects of a disease, and treatment cost is low, the feature such as have no side effect, and controls the advantages such as recurrence rate after healing is low.

Detailed description of the invention:

Embodiment 1:

A kind of Traditional Chinese drug mixture treating urticaria, is made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 10-30 part, Radix Curcumae 5-15 part, Cortex Moutan 5-15 part, Semen Persicae 5-15 part, Radix Scutellariae 5-15 part, Radix Codonopsis 5-15 part, Rhizoma Pinelliae 5-15 part, Rhizoma Zingiberis Recens 1-5 part, Radix Glycyrrhizae Preparata 5-15 part, Fructus Jujubae 5-15 part, Herba Ephedrae 3-8 part, Herba Asari 3-8 part.

Embodiment 2: a kind of Traditional Chinese drug mixture treating urticaria, is made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 15 parts, Radix Curcumae 10 parts, Cortex Moutan 10 parts, 10 parts of Semen Persicae, Radix Scutellariae 10 parts, Radix Codonopsis 10 parts, the Rhizoma Pinelliae 10 parts, 3 parts of Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata 10 parts, Fructus Jujubae 10 parts, 6 parts of Herba Ephedrae, Herba Asari 6 parts.

Embodiment 3:

A kind of Traditional Chinese drug mixture treating urticaria, is then made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 20 parts, Radix Curcumae 15 parts, Cortex Moutan 15 parts, 15 parts of Semen Persicae, Radix Scutellariae 15 parts, Radix Codonopsis 15 parts, the Rhizoma Pinelliae 15 parts, 5 parts of Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata 15 parts, Fructus Jujubae 15 parts, 8 parts of Herba Ephedrae, Herba Asari 8 parts.

My institute has altogether in recent years accepts urticaria patient 225 example for medical treatment, male 130 example, women 95 example, minimum 10 years old of age, maximum 67 years old.

The following is my institute's therapeutic effect standard to urticaria.

Cure: after treatment, erythra and scratchiness are completely eliminated, drug withdrawal nothing recurrence in 3 months.

Take a turn for the better: erythra disappears substantially, and scratchiness has clear improvement, and still has welt to show effect, but the size of welt outbreak and number of times significantly reduce.

Invalid: after treating 2 courses for the treatment of, it is not improved before each symptom and treatment.

Therapeutic Method:

Using traditional decocting for Chinese herbal medicine method, every day 1 dose, decoct twice, a point morning and evening takes on an empty stomach. It within 10th, it is a course for the treatment of.

After the treatment of 2-3 the course for the treatment of, 80 examples of fully recovering, take a turn for the better 134 examples, and invalid 11 examples, total effective rate reaches more than the 90% of total number of persons.

Concrete case:

1, patient Liu, female 45 years old, after edible maror was gone on business in private prosecution during patient assessment before 1 year, namely plays red welt next day, scratchiness is strong, substantially disappears through treatment welt, and patient is drug withdrawal stopped treatment just, the recent state of an illness breaks out, and sporadic welt occurs in whole body, and scratchiness is strong. After taking 2 courses for the treatment of of Drug therapy of the present invention, welt disappears substantially, and scratchiness has clear improvement, again recovery from illness after 3 courses for the treatment of of medication treatment, after follow up a case by regular visits to drug withdrawal over the past half year without recurring.

2, patient Liu, man 35 years old, after during patient assessment, before private prosecution two days, house decoration contacts a large amount of dust, this day cervical region, behind etc. its a large amount of welts, scratchiness is strong. After taking 2 courses for the treatment of of Drug therapy of the present invention, welt disappears substantially, and scratchiness has clear improvement, again recovery from illness after 2 courses for the treatment of of medication treatment, after follow up a case by regular visits to drug withdrawal 3 months over without recurring.

3, Lee so-and-so, man 10 years old, when infant is medical, the patient head of a family claims one week sky, and band infant goes to park to play, and when going home latter second day to get up, just plays many places welt with discovery, and scratchiness is strong. After taking 1 course for the treatment of of Drug therapy of the present invention, welt is obviously reduced, and scratchiness has clear improvement, again recovery from illness after 2 courses for the treatment of of medication treatment, after follow up a case by regular visits to drug withdrawal 3 months over without recurring.

Claims

1. the Traditional Chinese drug mixture treating urticaria, it is characterised in that be made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 10-30 part, Radix Curcumae 5-15 part, Cortex Moutan 5-15 part, Semen Persicae 5-15 part, Radix Scutellariae 5-15 part, Radix Codonopsis 5-15 part, Rhizoma Pinelliae 5-15 part, Rhizoma Zingiberis Recens 1-5 part, Radix Glycyrrhizae Preparata 5-15 part, Fructus Jujubae 5-15 part, Herba Ephedrae 3-8 part, Herba Asari 3-8 part.

2. a kind of Traditional Chinese drug mixture treating urticaria according to claim 1, it is characterised in that be made up of the raw material of Chinese medicine of following composition by weight: Radix Bupleuri 15 parts, Radix Curcumae 10 parts, Cortex Moutan 10 parts, 10 parts of Semen Persicae, Radix Scutellariae 10 parts, Radix Codonopsis 10 parts, the Rhizoma Pinelliae 10 parts, 3 parts of Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata 10 parts, Fructus Jujubae 10 parts, 6 parts of Herba Ephedrae, Herba Asari 6 parts.