CN103990002A - Traditional Chinese medicinal composition for treating liver cancer - Google Patents

Traditional Chinese medicinal composition for treating liver cancer Download PDF

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Publication number
CN103990002A
CN103990002A CN201410253980.6A CN201410253980A CN103990002A CN 103990002 A CN103990002 A CN 103990002A CN 201410253980 A CN201410253980 A CN 201410253980A CN 103990002 A CN103990002 A CN 103990002A
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herba
traditional chinese
chinese medicine
liver cancer
chinese medicinal
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CN201410253980.6A
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王艳军
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Abstract

The invention belongs to the technical field of traditional Chinese medicaments, and particularly relates to a traditional Chinese medicinal composition for treating liver cancer. The composition is prepared from the following raw materials by weight: 10-80g of cleavers, 10-60g of concha meretricis seu cyclinae, 10-50g of seaweed, 10-60g of rabdosia lophanthide, 10-40g of goldhair hedyotis herb, 10-70g of selaginella doederleinii hieron, 10-45g of cephalotaxus fortunei, 10-50g of asparagus and 10-60g of kirilow groundsel herb, is exact in curative effect, high in effective rate, simple in raw materials and low in cost, does not have toxic or side effects, and can be used for greatly reducing the economical burden of patients.

Description

The Chinese medicine composition of Hepatoma therapy
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition of Hepatoma therapy.
Background technology
Hepatocarcinoma can betide any age, but take 31~50 years old as many, and men and women's ratio is about 8: 1.In more than 90% belonging to when making a definite diagnosis, late period, surgical engine can many miss, so adopt modern comprehensive treatment often because Radiotherapy chemotherapy and immunization therapy are subject to certain limitation; And Radiotherapy chemotherapy is very big to the treatment toxicity of primary disease, indication reduces, and curative effect is also poor; Though interventional therapy has certain curative effect, need quite high condition and equipment, spend also larger.Therefore Chinese medicine has become one of primary treatment means of primary disease.Chinese medicine also with Radiotherapy chemotherapy fit applications, can play preferably " attenuation synergistic " effect.
The cause of disease of hepatocarcinoma, it is relevant with chronic hepatic diseases, aflatoxin, parasite, excessive drinking, inherited genetic factors that doctor trained in Western medicine is thought mainly.In China, be related to that with onset of liver cancer rate the factor of maximum is hepatitis B virus, particularly HBsAg positive.Therefore, HBsAg positive and patients with chronic liver are listed in the high-risk group of hepatocarcinoma.Have research to think, HBsAg has directly carcinogenic possibility, and not necessarily by this interstage of chronic hepatopathy.
The traditional Chinese medical science thinks that primary disease is mainly lost by internal organs asthenia of qi and blood, insufficiency of the spleen wet poly-, the expectorant blood coagulation stasis of blood; The evil poison invasion of six climate exopathogens, evil solidifying poison knot, internal injury caused by excess of seven emotions, depressed emotions etc., can make gas, blood, wet, heat, the stasis of blood, poison tie and form hepatocarcinoma mutually.Primary disease disease located in liver, closely related with spleen, gallbladder, stomach, main pathogenesis is weakened body resistance in interior, evil poison pents up.
By dialectical opinion, control, hepatocarcinoma is divided into following five types: 1, liver qi stagnation type disease is seen pain in chest and hypochondrium, uncomfortable in chest easypro, angry postemphasis, hepatomegaly, anorexia, thin white fur of tongue, stringy pulse.Controlling should depressed liver-energy dispersing and QI regulating.2, stagnation of dampness due to deficiency of the spleen type disease sees that breast coerces vexed pain, the lower mass in the abdomen of the side of body, and inappetence, or nauseating belch, weak, or loose stool, there is indentation on light red tongue limit, white and thin fur, deep-slow pulse.Controlling should invigorating the spleen to clear away damp pathogen.3, qi stagnation and blood stasis type disease is seen distending pain in the chest and hypochondrium, and sore spot is fixing not to be moved, and more so, coerce lower mass in the abdomen night, belch or singultus, and abdominal distention and anorexia, dry stool oliguria, purplish tongue secretly has ecchymosis, white and thin fur or greasy, thready and hesitant pulse.Control suitable blood circulation promoting and blood stasis dispelling, hard masses softening and resolving.4, liver gallbladder damp-heat type disease is seen upper abdominal lump, distension and fullness in the abdomen, and order skin xanthochromia, enlarged abdomen is as drum, vexed bitter taste, the anorexia of feeling sick, constipation is drowned yellow, and purplish tongue is dark, thick, yellow and greasy fur, slippery and rapid pulse.Control suitable eliminating damp-heat, change silt eliminating stagnation.5, liver-kidney yin deficiency disease is seen distending pain over the hypochondrium, become thin weak, and low grade fever night sweat, dysphoria with feverish sensation in the chest palms and soles, skin is dark and gloomy, dry stool oliguria, the few tongue of red tongue, thready and rapid pulse.Control suitable nourishing YIN and clearing away heat, right supporting anticancer.Above typing is typical pattern of syndrome, but simulataneous insufficiency and excessive often is clinically clinical in distinguishing and control with card.General take the stagnation of QI as main in early days, take blood stasis, cold-damp mid-term as main, late period many hepatic and renal YIN deficiency.
Hepatocarcinoma can betide any age, but take 31~50 years old as many, and men and women's ratio is about 8: 1.In more than 90% belonging to when making a definite diagnosis, late period, surgical engine can many miss, so adopt modern comprehensive treatment often because Radiotherapy chemotherapy and immunization therapy are subject to certain limitation; And Radiotherapy chemotherapy is very big to the treatment toxicity of primary disease, indication reduces, and curative effect is also poor; Though interventional therapy has certain curative effect, need quite high condition and equipment, spend also larger.Therefore Chinese medicine has become one of primary treatment means of primary disease.Chinese medicine also with Radiotherapy chemotherapy fit applications, can play preferably " attenuation synergistic " effect.
Summary of the invention
The object of the present invention is to provide a kind of Hepatoma therapy determined curative effect, effective percentage is high, the Chinese medicine composition having no side effect.
The technical solution adopted for the present invention to solve the technical problems is: the Chinese medicine composition of Hepatoma therapy, by following weight proportioning raw material make: Herba Galii Teneri 10-80g, Concha Meretricis seu Cyclinae 10-60g, Sargassum 10-50g, Herba Rabdosiae Lophanthoidis 10-60g, Herba Salviae Chinensis 10-40g, Herba Selaginellae Doederleinii 10-70g, Folium et Ramulus Cephalotaxi 10-45g, Germinatus Phragmitis 10-50g, Herba Senecionis Kirilowi 10-60g.
Preferably, the Chinese medicine composition of Hepatoma therapy, by following weight proportioning raw material make: Herba Galii Teneri 50g, Concha Meretricis seu Cyclinae 30g, Sargassum 30g, Herba Rabdosiae Lophanthoidis 30g, Herba Salviae Chinensis 20g, Herba Selaginellae Doederleinii 30g, Folium et Ramulus Cephalotaxi 20g, Germinatus Phragmitis 30g, Herba Senecionis Kirilowi 30g.
Usage: be decocted in water for oral dose, 1 dose of every day, 2 times on the one, each 1 time sooner or later.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
Herba Galii Teneri, pungent, bitter, cool, heat-clearing and toxic substances removing, inducing diuresis to remove edema.Cure mainly flu, gingival hemorrhage, acute and chronic appendicitis, urinary system infection, edema, dysmenorrhea, metrorrhagia, leucorrhea, cancer, leukemia; External is controlled mastitis from the beginning of, carbuncle furuncle and phyma poison, traumatic injury.
Concha Meretricis seu Cyclinae, salty, flat, GUIXIN, kidney channel, heat clearing away, diuretic, reduces phlegm, softening the hard mass.Control heat-phlegm and breathe heavily and cough, edema, gonorrhea, wart, tumor, gather, blood agglomeration chest pain, dysentery, hemorrhoid, metrorrhagia, leukorrhagia.
Sargassum, bitter in the mouth, salty, cold in nature, return lung, spleen, kidney, liver stomach warp, softening the hard mass; Expectorant; Diuretic; Detumescent.Thyromegaly, a submental lymph nodes tuberculosis.Eliminating stagnation gas carbuncle, abdomen inner product piece, distending pain, the ring of abdomen hollow.Also can descend 12 kinds of edema, treat between skin and gather sudden and violent bursting, stay depressed heat, diuresis.
Herba Rabdosiae Lophanthoidis, hardship, cold, clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis.Control acute hepatitis, acute cholecystitis, dysentery, enteritis, the difficulty in urination, traumatic injury congestive edema.
Herba Salviae Chinensis, pungent, bitter, flat, return kidney, urinary bladder channel, clearing away heat-damp and promoting diuresis, detoxicating and resolving stagnation of pathogens, cooling blood for hemostasis.For insufficiency of the spleen wet poly-, the esophageal carcinoma that mental disorder is condensed, carcinoma of gastric cardia, gastric cancer etc., be shown in dysphagia, dysphagia, vomiting sputum etc.Be used for retention of damp-heat in the interior, wet poly-malicious hepatocarcinoma of containing, see and coerce lower twinge, jaundice, ascites swelling etc.
Herba Selaginellae Doederleinii, sweet in the mouth, micro-hardship, puckery, cool in nature, heat-clearing and toxic substances removing, expelling wind and removing dampness, hemostasis, anticancer.
Folium et Ramulus Cephalotaxi, bitter, puckery, cold, relieve internal heat anticancer.
Germinatus Phragmitis, bitter in the mouth, sweet, slightly warm in nature, returns lung meridian, and invigorating the spleen and benefiting QI is nourshing Yin and drynsessmoistening prescription, promotes the production of body fluid and quenches one's thirst, anticancer removing toxic substances.Cure mainly: pulmonary tuberculosis chronic cough is more than; Various cancers, general lassitude is weak, inappetence etc.
Herba Senecionis Kirilowi, bitter, micro-sweet, cold, heat-clearing and toxic substances removing, diuresis.For lung abscess, urinary tract infection, dysuria, leukemia, stomatitis, furuncle and phyma.
The present invention has following beneficial effect: medicine composite for curing therapeutic efficacy for hepatic carcinoma of the present invention is definite, and effective percentage is high, have no side effect, and raw material is simple, with low cost, greatly alleviates patient's financial burden.
The specific embodiment
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiment.Every do not deviate from the change of the present invention design or be equal to substitute include within protection scope of the present invention.
Embodiment 1
The Chinese medicine composition of Hepatoma therapy, by following weight proportioning raw material make: Herba Galii Teneri 10g, Concha Meretricis seu Cyclinae 60g, Sargassum 20g, Herba Rabdosiae Lophanthoidis 60g, Herba Salviae Chinensis 30g, Herba Selaginellae Doederleinii 50g, Folium et Ramulus Cephalotaxi 10g, Germinatus Phragmitis 50g, Herba Senecionis Kirilowi 60g.
Embodiment 2
The Chinese medicine composition of Hepatoma therapy, by following weight proportioning raw material make: Herba Galii Teneri 50g, Concha Meretricis seu Cyclinae 30g, Sargassum 30g, Herba Rabdosiae Lophanthoidis 30g, Herba Salviae Chinensis 20g, Herba Selaginellae Doederleinii 30g, Folium et Ramulus Cephalotaxi 20g, Germinatus Phragmitis 30g, Herba Senecionis Kirilowi 30g.
Embodiment 3
The Chinese medicine composition of Hepatoma therapy, by following weight proportioning raw material make: Herba Galii Teneri 80g, Concha Meretricis seu Cyclinae 50g, Sargassum 10g, Herba Rabdosiae Lophanthoidis 30g, Herba Salviae Chinensis 10g, Herba Selaginellae Doederleinii 10g, Folium et Ramulus Cephalotaxi 45g, Germinatus Phragmitis 20g, Herba Senecionis Kirilowi 10g.
Embodiment 4
The Chinese medicine composition of Hepatoma therapy, by following weight proportioning raw material make: Herba Galii Teneri 30g, Concha Meretricis seu Cyclinae 10g, Sargassum 50g, Herba Rabdosiae Lophanthoidis 10g, Herba Salviae Chinensis 40g, Herba Selaginellae Doederleinii 70g, Folium et Ramulus Cephalotaxi 35g, Germinatus Phragmitis 10g, Herba Senecionis Kirilowi 50g.
In side, Herba Galii Teneri heat-clearing and toxic substances removing, reducing swelling and alleviating pain, diuresis dissipating blood stasis; Concha Meretricis seu Cyclinae clearing away heat-damp and promoting diuresis, dissipating phlegm and resolving masses; Herba Scutellariae Barbatae heat clearing away, removing toxic substances, dissipating blood stasis, hemostasis, analgesic therapy; Sargassum heat clearing away, hard masses softening and resolving; Herba Rabdosiae Lophanthoidis clearing away heat-damp and promoting diuresis, jaundice eliminating damp eliminating, cool the blood dissipate blood stasis; Herba Salviae Chinensis removing toxic substances, detumescence; Herba Selaginellae Doederleinii subduing swelling and detoxicating, wind dispelling cold expelling, hemostasia and promoting granulation and anticancer; Folium et Ramulus Cephalotaxi relieves internal heat anticancer; Germinatus Phragmitis not only has anticancer effect, and in asparagus spear, contains the trace element etc. of rich in protein, vitamin, mineral and needed by human body, has adjusting organism metabolism, improves the effect of body immunity; Herba Senecionis Kirilowi heat-clearing and toxic substances removing, inducing diuresis to remove edema.All medicine compatibilities, play soothing liver-QI dissipating blood stasis, hard masses softening and resolving, heat-clearing and toxic substances removing, anticancer effect altogether.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
Patient's data: liver cancer patient is totally 72 examples, male patient's 49 examples wherein, female patient 23 examples, early hepatocarcinoma patient 30 examples, mid and late liver cancer patient 42 examples, 40 years old of age minimum, maximum 69 years old, 51 years old mean age.
Symptoms: hepatalgia, poor appetite, weak, become thin, abdominal distention, heating, jaundice common sympton.
Therapeutic Method: Chinese medicine composition of the present invention is decocted in water for oral dose, 1 dose of every day, 2 times on the one, each 1 time sooner or later one month is 1 course for the treatment of.
Curative effect judging standard:
Cure: clinical symptom disappearance, foci disappearance, not recurrence above in a year after drug withdrawal;
Effective: clinical symptoms is clearly better, focus is obviously dwindled;
Invalid: clinical symptoms has no improvement, or continue to worsen.
Therapeutic outcome: cure 24 examples in 30 routine early hepatocarcinoma patients, effective 6 examples, cure 10 examples in 42 routine mid and late liver cancer patients, effective 27 examples, invalid 5 examples, total effective rate 93%, take after Chinese medicine of the present invention, there is not other side reactions in patient, have no side effect except hepatocarcinoma clinical symptoms.
Model case 1
Lee * *, man, 68 years old, realizes that epigastrium has lump, twinge recently, spiritlessness and weakness, shallow complexion, poor appetite, abdominal distention, hepatic region palpation can touch matter obvious tuberosity firmly, deep red tongue, tongue is few yellow greasy, stringy,thready and rapid pulse, card belongs to Zhong Yi mass in the abdomen (doctor trained in Western medicine is referred to as primary hepatocarcinoma).With this side plus-minus treatment 1 month, symptom obviously alleviated, and 2 courses for the treatment of of defence's following the service, within 1 year, had no recurrence, and patient is energetic, secretly advises its family members, advised that it is quitted smoking, wine, greasy product.
Model case 2
Pungent * *, female, 47 years old, patient's liver pain was uncomfortable, become thin 6 months, and B ultrasonic, CT examination are found approximately 3 * 4cm of tumor size.Through taking Chinese medicine of the present invention after 2 courses for the treatment of, patient's subjective symptoms obviously alleviates, and hospital's check tumor is reduced into 1 * 2cm, continues to take 2 courses for the treatment of, and check tumor disappears, and advises it to avoid rich food dish, follows up a case by regular visits to not recurrence in a year.

Claims (2)

1. the Chinese medicine composition of Hepatoma therapy, is characterized in that, by following weight proportioning raw material make: Herba Galii Teneri 10-80g, Concha Meretricis seu Cyclinae 10-60g, Sargassum 10-50g, Herba Rabdosiae Lophanthoidis 10-60g, Herba Salviae Chinensis 10-40g, Herba Selaginellae Doederleinii 10-70g, Folium et Ramulus Cephalotaxi 10-45g, Germinatus Phragmitis 10-50g, Herba Senecionis Kirilowi 10-60g.
2. the Chinese medicine composition of Hepatoma therapy as claimed in claim 1, is characterized in that, by following weight proportioning raw material make: Herba Galii Teneri 50g, Concha Meretricis seu Cyclinae 30g, Sargassum 30g, Herba Rabdosiae Lophanthoidis 30g, Herba Salviae Chinensis 20g, Herba Selaginellae Doederleinii 30g, Folium et Ramulus Cephalotaxi 20g, Germinatus Phragmitis 30g, Herba Senecionis Kirilowi 30g.
CN201410253980.6A 2014-06-10 2014-06-10 Traditional Chinese medicinal composition for treating liver cancer Pending CN103990002A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434826A (en) * 2015-12-31 2016-03-30 青岛昌安达药业有限公司 Traditional Chinese medicine composition for treating liver cancer
CN105878829A (en) * 2016-04-13 2016-08-24 董伟 Traditional Chinese medicine composition for treating liver cancer
CN105998719A (en) * 2016-07-29 2016-10-12 张子志 Medicine for treating liver cancer and preparation method thereof
CN110051741A (en) * 2019-04-24 2019-07-26 赵九海 A kind of Traditional Chinese medicine liniment and preparation method thereof for treating liver cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1237452A (en) * 1999-04-12 1999-12-08 黄强 Cold tea for resisting cancer and preventing cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1237452A (en) * 1999-04-12 1999-12-08 黄强 Cold tea for resisting cancer and preventing cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘延泽 等: "中草药中发现新抗癌药物的途径", 《现代药物与临床》 *
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434826A (en) * 2015-12-31 2016-03-30 青岛昌安达药业有限公司 Traditional Chinese medicine composition for treating liver cancer
CN105878829A (en) * 2016-04-13 2016-08-24 董伟 Traditional Chinese medicine composition for treating liver cancer
CN105998719A (en) * 2016-07-29 2016-10-12 张子志 Medicine for treating liver cancer and preparation method thereof
CN110051741A (en) * 2019-04-24 2019-07-26 赵九海 A kind of Traditional Chinese medicine liniment and preparation method thereof for treating liver cancer

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Inventor after: Wang Yanjun

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