CN103736051A - Hemangioma nursing medicament and preparation method thereof - Google Patents

Hemangioma nursing medicament and preparation method thereof Download PDF

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Publication number
CN103736051A
CN103736051A CN201310742754.XA CN201310742754A CN103736051A CN 103736051 A CN103736051 A CN 103736051A CN 201310742754 A CN201310742754 A CN 201310742754A CN 103736051 A CN103736051 A CN 103736051A
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radix
herba
root
herb
hemangioma
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刘玉含
臧萍
于义琴
王岩
管淑红
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Abstract

The invention discloses a hemangioma nursing medicament and a preparation method thereof. A pure Chinese medicinal formula is adopted in the medicament. The hemangioma nursing medicament is mainly prepared from the following Chinese herbal medicine: astragalus, dangshen, red-rooted salvia root, Chinese angelica, barbed skullcap herb, spreading hedyotis herb, large-head atractylodes rhizome, chicken gizzard membrane, umbellate pore fungus, turmeric root-tuber, Indian mockstrawberry herb, ternate buttercup root, pseudo-ginseng root, leech, toad venom, giant knotweed root, acanthopanax root, ginger carbo, herba soroseris, dahurian patrinia herb, bigleaf beautyberry leaf, goose's throat, roasted liquoric root, snakeskin, discolor cinquefoil herb, fineleaf schizonepeta herb, safflower, paris rhizome, longhairy antenoron herb, hawthorn, cortex eucommiae, dogbane leaf, Chinese taxillus twig, spanishneedles herb, rehmannia root, dragon bone, pubescent holly root and common rush. The hemangioma nursing medicament has the advantages of remarkable curative effect, prevention of relapse and no side effect.

Description

A kind of hemangioma care drug and preparation method thereof
Technical field
The present invention relates to a kind of hemangioma care drug and preparation method thereof.
Background technology
Hemangioma is congenital benign tumor or vascular malformation, while being more common in baby due or birth after soon, it originates from remaining embryo angioblast, the hemangioma that betides oral cavity forehead accounts for the whole province angiomatous 60%, wherein great majority betide facial skin, subcutaneous tissue and oral mucosa, as tissues such as tongue, lip, mouthful ends, minority betides in frontal bone or deep tissue.Angiomatous treatment is all generally to adopt Western medicine or these methods of performing the operation, Western medicine that can be most is all with very strong side effect, and patient's major part is all again baby, and side effect is just larger on the impact of health, but with the colleague of larger side effect, curative effect is not but very high; The method of operative treatment in addition, although curative effect is high, can baby is performed the operation, difficulty is more much larger than adult, so expense is also more expensive, after operation, may infect in addition, and have very high recurrence probability.
Summary of the invention
Technical problem to be solved by this invention is to provide one and has evident in efficacyly, is difficult for recurrence, and the hemangioma care drug having no side effect.
For addressing the above problem, the present invention is achieved through the following technical solutions:
A kind of hemangioma care drug, described this medicine is pure Chinese medicine formula, mainly by following Chinese herbal medicine, is made: the Radix Astragali, Radix Codonopsis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Endothelium Corneum Gigeriae Galli, Polyporus, Radix Curcumae, Herba Duchesneae Indicae, Radix Ranunculi Ternati, Radix Notoginseng, Hirudo, Venenum Bufonis, speckle village root, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Zingiberis Recens charcoal, thin,tough silk hair chrysanthemum, Herba Patriniae, Folium Callicarpae Formosanae, Fauces trachea seu esophagus, Radix Glycyrrhizae Preparata, Periostracum Serpentis, Herba Potentillae Discoloris, Herba Schizonepetae, Flos Carthami, Rhizoma Paridis, Herba Lysimachiae, Fructus Crataegi, the Cortex Eucommiae, Herba Apocyni veneti, folded parasitism, Herba Bidentis Bipinnatae, Rhizoma Phragmitis, Os Draconis, Radix Ilicis Pubescentis and Juncus effcus, described each Chinese herbal medicine weight portion proportioning is: Radix Astragali 20g, Radix Codonopsis 10g, Radix Salviae Miltiorrhizae 10g, Radix Angelicae Sinensis 20g, Herba Scutellariae Barbatae 25g, Herba Hedyotidis Diffusae 35g, Rhizoma Atractylodis Macrocephalae 15g, Endothelium Corneum Gigeriae Galli 20g, Polyporus 20g, Radix Curcumae 10g, Herba Duchesneae Indicae 20g, Radix Ranunculi Ternati 36g, Radix Notoginseng 12g, Hirudo 5g, Venenum Bufonis 1g, speckle village root 20g, Radix Et Caulis Acanthopanacis Senticosi 25g, Rhizoma Zingiberis Recens charcoal 10g, thin,tough silk hair chrysanthemum 12g, Herba Patriniae 25g, Folium Callicarpae Formosanae 20g, Fauces trachea seu esophagus 8g, Radix Glycyrrhizae Preparata 15g, Periostracum Serpentis 10g, Herba Potentillae Discoloris 15g, Herba Schizonepetae 40g, Flos Carthami 30g, Rhizoma Paridis 18g, Herba Lysimachiae 20g, Fructus Crataegi 20g, Cortex Eucommiae 15g, Herba Apocyni veneti 30g, folded parasitic 15g, Herba Bidentis Bipinnatae 25g, Rhizoma Phragmitis 10g, Os Draconis 7g, Radix Ilicis Pubescentis 10g and Juncus effcus 12g.
Another technical problem to be solved by this invention is to provide one and has evident in efficacyly, is difficult for recurrence, and the manufacture method of the hemangioma care drug having no side effect.
The present invention is achieved through the following technical solutions: the manufacturing process of described hemangioma care drug is as follows:
A, Venenum Bufonis, Periostracum Serpentis, Os Draconis and Hirudo are ground to form to fine powder, filter with 600 mesh sieves, standby;
B, will Radix Codonopsis and Radix Salviae Miltiorrhizae in the middle of empty, the fine powder extracting in step " A " is put into the centre of Radix Codonopsis and Radix Codonopsis, with the vexed steaming twice of vinegar, with slow fire, steam 4-6 hour for the first time, steam with high heat 1 hour for the second time;
C, vexed steamed Radix Codonopsis and Radix Salviae Miltiorrhizae in step " B " are put into distilled water decoct 2 hours, filter with 500 mesh sieves, extract medicinal liquid, standby;
D, by the Radix Astragali, Radix Angelicae Sinensis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Endothelium Corneum Gigeriae Galli, Polyporus, Radix Curcumae, Herba Duchesneae Indicae, Radix Ranunculi Ternati, Radix Notoginseng, speckle village root, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Zingiberis Recens charcoal, thin,tough silk hair chrysanthemum, Herba Patriniae, Folium Callicarpae Formosanae, Fauces trachea seu esophagus, Radix Glycyrrhizae Preparata, Herba Potentillae Discoloris, Herba Schizonepetae, Flos Carthami, Rhizoma Paridis, Herba Lysimachiae, Fructus Crataegi, the Cortex Eucommiae, Herba Apocyni veneti, folded parasitic, Herba Bidentis Bipinnatae, Rhizoma Phragmitis, Radix Ilicis Pubescentis and Juncus effcus decoct with water twice, the water yield was not there to be powder to be advisable, decocting time is 2-3 hour for the first time, decocting time is 1-2 hour for the second time, after decocting well, standing 16 hours, filter and extract medicinal liquid,
E, the medicinal liquid of standing 16 hours is mixed with the medicinal liquid extracting in " C " step decoct 2 times, 3 hours for the first time, 2 hours for the second time, with 600 mesh sieves filter, extraction medicinal liquid, standby;
F, the medicinal liquid of " E " step gained is added to PH debugging agent, pH value is adjusted to prescribed limit, the capping of bottling afterwards.
The beneficial effect of a kind of hemangioma care drug of the present invention and preparation method thereof is: adopt pure Chinese drug preparation to form, and without any side effects, be difficult for recurrence, and evident in efficacy.
The specific embodiment
Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.
Embodiment:
A kind of hemangioma care drug of the present invention, described this medicine is pure Chinese medicine formula, mainly by following Chinese herbal medicine, is made: the Radix Astragali, Radix Codonopsis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Endothelium Corneum Gigeriae Galli, Polyporus, Radix Curcumae, Herba Duchesneae Indicae, Radix Ranunculi Ternati, Radix Notoginseng, Hirudo, Venenum Bufonis, speckle village root, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Zingiberis Recens charcoal, thin,tough silk hair chrysanthemum, Herba Patriniae, Folium Callicarpae Formosanae, Fauces trachea seu esophagus, Radix Glycyrrhizae Preparata, Periostracum Serpentis, Herba Potentillae Discoloris, Herba Schizonepetae, Flos Carthami, Rhizoma Paridis, Herba Lysimachiae, Fructus Crataegi, the Cortex Eucommiae, Herba Apocyni veneti, folded parasitism, Herba Bidentis Bipinnatae, Rhizoma Phragmitis, Os Draconis, Radix Ilicis Pubescentis and Juncus effcus, described each Chinese herbal medicine weight portion proportioning is: Radix Astragali 20g, Radix Codonopsis 10g, Radix Salviae Miltiorrhizae 10g, Radix Angelicae Sinensis 20g, Herba Scutellariae Barbatae 25g, Herba Hedyotidis Diffusae 35g, Rhizoma Atractylodis Macrocephalae 15g, Endothelium Corneum Gigeriae Galli 20g, Polyporus 20g, Radix Curcumae 10g, Herba Duchesneae Indicae 20g, Radix Ranunculi Ternati 36g, Radix Notoginseng 12g, Hirudo 5g, Venenum Bufonis 1g, speckle village root 20g, Radix Et Caulis Acanthopanacis Senticosi 25g, Rhizoma Zingiberis Recens charcoal 10g, thin,tough silk hair chrysanthemum 12g, Herba Patriniae 25g, Folium Callicarpae Formosanae 20g, Fauces trachea seu esophagus 8g, Radix Glycyrrhizae Preparata 15g, Periostracum Serpentis 10g, Herba Potentillae Discoloris 15g, Herba Schizonepetae 40g, Flos Carthami 30g, Rhizoma Paridis 18g, Herba Lysimachiae 20g, Fructus Crataegi 20g, Cortex Eucommiae 15g, Herba Apocyni veneti 30g, folded parasitic 15g, Herba Bidentis Bipinnatae 25g, Rhizoma Phragmitis 10g, Os Draconis 7g, Radix Ilicis Pubescentis 10g and Juncus effcus 12g.
The preparation process of described a kind of hemangioma care drug is as follows:
A, Venenum Bufonis, Periostracum Serpentis, Os Draconis and Hirudo are ground to form to fine powder, filter with 600 mesh sieves, standby;
B, will Radix Codonopsis and Radix Salviae Miltiorrhizae in the middle of empty, the fine powder extracting in step " A " is put into the centre of Radix Codonopsis and Radix Codonopsis, with the vexed steaming twice of vinegar, with slow fire, steam 4-6 hour for the first time, steam with high heat 1 hour for the second time;
C, vexed steamed Radix Codonopsis and Radix Salviae Miltiorrhizae in step " B " are put into distilled water decoct 2 hours, filter with 500 mesh sieves, extract medicinal liquid, standby;
D, by the Radix Astragali, Radix Angelicae Sinensis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Endothelium Corneum Gigeriae Galli, Polyporus, Radix Curcumae, Herba Duchesneae Indicae, Radix Ranunculi Ternati, Radix Notoginseng, speckle village root, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Zingiberis Recens charcoal, thin,tough silk hair chrysanthemum, Herba Patriniae, Folium Callicarpae Formosanae, Fauces trachea seu esophagus, Radix Glycyrrhizae Preparata, Herba Potentillae Discoloris, Herba Schizonepetae, Flos Carthami, Rhizoma Paridis, Herba Lysimachiae, Fructus Crataegi, the Cortex Eucommiae, Herba Apocyni veneti, folded parasitic, Herba Bidentis Bipinnatae, Rhizoma Phragmitis, Radix Ilicis Pubescentis and Juncus effcus decoct with water twice, the water yield was not there to be powder to be advisable, decocting time is 2-3 hour for the first time, decocting time is 1-2 hour for the second time, after decocting well, standing 16 hours, filter and extract medicinal liquid,
E, the medicinal liquid of standing 16 hours is mixed with the medicinal liquid extracting in " C " step decoct 2 times, 3 hours for the first time, 2 hours for the second time, with 600 mesh sieves filter, extraction medicinal liquid, standby;
F, the medicinal liquid of " E " step gained is added to PH debugging agent, pH value is adjusted to prescribed limit, the capping of bottling afterwards.
The using method of product hemangioma care drug of the present invention: adopt muscle injection mode, each consumption 3-5g,
One week once, two months was a course for the treatment of.
Experimental example 1:
Experimental subject: 150 have the people of hemangioma performance, the age, between 1-6 month, according to using different pharmaceutical, is divided into two groups, every group of 75 people.
Experimental technique: two groups of personnel use respectively the medicine of 2 months, first group of patient infusion product medicine of the present invention, second group of patient infusion other medicines.
Experimental result:
Figure BDA0000449307820000041
(note: hemangioma is congenital benign tumor, is more common in baby, determines whether performing the operation according to diameter.)
Experimental example 2:
Experimental subject: 150 postoperative patients of hemangioma, the age, between 1-6 month, according to using medicine difference, is divided into two groups, every group of 75 people.
Experimental technique: two groups of personnel use respectively the medicine of 2 months, first group is used product medicine of the present invention, and second group is used other medicines.
Experiment purpose: observe hands postoperative patient and carry out after medicaments nursing, have or not recurrence and side effect.
(note: the unstable expression of situation is not recurrence temporarily, but has very large probability to recur.)
From above experimental result, use the hemangioma care drug of product of the present invention, no matter be to angiomatous control and treatment, or angiomatous recurrence is prevented to have the curative effect of highly significant; And because product of the present invention adopts pure Chinese drug preparation, without any side effects to human body.
Typical case:
Money, suffers from congenital hemangioma with regard to tested finding in the time of large in 4 months, and hospital takes surgical measure to excise money hemangioma with it.Can be after 1 year, the hemangioma recurrence of money, owing to carrying out hands art one time, and postoperative recurrence, money household determines to adopt medicine control, regularly allow money use care drug, can play the slowly effect of digestion to hemangioma on the one hand, can prevent again on the one hand its recurrence, can be through the regular use of more than four months, hemangioma there is no situation about diminishing, after this situation, money household has changed care drug, bring into use product medicine of the present invention, using after about 3 months, examination in hospital, the hemangioma of money obviously diminishes, and in continual and steady reducing.
Below the present invention is described in detail, the above, be only the present invention's preferred embodiment, when not limiting the scope of the present invention, allly according to the application's scope, does impartial variation and modification, all should still belong in covering scope of the present invention.

Claims (2)

1. a hemangioma care drug, described this medicine is pure Chinese medicine formula, mainly by following Chinese herbal medicine, is made: the Radix Astragali, Radix Codonopsis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Endothelium Corneum Gigeriae Galli, Polyporus, Radix Curcumae, Herba Duchesneae Indicae, Radix Ranunculi Ternati, Radix Notoginseng, Hirudo, Venenum Bufonis, speckle village root, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Zingiberis Recens charcoal, thin,tough silk hair chrysanthemum, Herba Patriniae, Folium Callicarpae Formosanae, Fauces trachea seu esophagus, Radix Glycyrrhizae Preparata, Periostracum Serpentis, Herba Potentillae Discoloris, Herba Schizonepetae, Flos Carthami, Rhizoma Paridis, Herba Lysimachiae, Fructus Crataegi, the Cortex Eucommiae, Herba Apocyni veneti, folded parasitism, Herba Bidentis Bipinnatae, Rhizoma Phragmitis, Os Draconis, Radix Ilicis Pubescentis and Juncus effcus, described each Chinese herbal medicine weight portion proportioning is: Radix Astragali 20g, Radix Codonopsis 10g, Radix Salviae Miltiorrhizae 10g, Radix Angelicae Sinensis 20g, Herba Scutellariae Barbatae 25g, Herba Hedyotidis Diffusae 35g, Rhizoma Atractylodis Macrocephalae 15g, Endothelium Corneum Gigeriae Galli 20g, Polyporus 20g, Radix Curcumae 10g, Herba Duchesneae Indicae 20g, Radix Ranunculi Ternati 36g, Radix Notoginseng 12g, Hirudo 5g, Venenum Bufonis 1g, speckle village root 20g, Radix Et Caulis Acanthopanacis Senticosi 25g, Rhizoma Zingiberis Recens charcoal 10g, thin,tough silk hair chrysanthemum 12g, Herba Patriniae 25g, Folium Callicarpae Formosanae 20g, Fauces trachea seu esophagus 8g, Radix Glycyrrhizae Preparata 15g, Periostracum Serpentis 10g, Herba Potentillae Discoloris 15g, Herba Schizonepetae 40g, Flos Carthami 30g, Rhizoma Paridis 18g, Herba Lysimachiae 20g, Fructus Crataegi 20g, Cortex Eucommiae 15g, Herba Apocyni veneti 30g, folded parasitic 15g, Herba Bidentis Bipinnatae 25g, Rhizoma Phragmitis 10g, Os Draconis 7g, Radix Ilicis Pubescentis 10g and Juncus effcus 12g.
2. a preparation method for hemangioma care drug as claimed in claim 1, is characterized in that: comprise the following steps:
A, Venenum Bufonis, Periostracum Serpentis, Os Draconis and Hirudo are ground to form to fine powder, filter with 600 mesh sieves, standby;
B, will Radix Codonopsis and Radix Salviae Miltiorrhizae in the middle of empty, the fine powder extracting in step " A " is put into the centre of Radix Codonopsis and Radix Codonopsis, with the vexed steaming twice of vinegar, with slow fire, steam 4-6 hour for the first time, steam with high heat 1 hour for the second time;
C, vexed steamed Radix Codonopsis and Radix Salviae Miltiorrhizae in step " B " are put into distilled water decoct 2 hours, filter with 500 mesh sieves, extract medicinal liquid, standby;
D, by the Radix Astragali, Radix Angelicae Sinensis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Endothelium Corneum Gigeriae Galli, Polyporus, Radix Curcumae, Herba Duchesneae Indicae, Radix Ranunculi Ternati, Radix Notoginseng, speckle village root, Radix Et Caulis Acanthopanacis Senticosi, Rhizoma Zingiberis Recens charcoal, thin,tough silk hair chrysanthemum, Herba Patriniae, Folium Callicarpae Formosanae, Fauces trachea seu esophagus, Radix Glycyrrhizae Preparata, Herba Potentillae Discoloris, Herba Schizonepetae, Flos Carthami, Rhizoma Paridis, Herba Lysimachiae, Fructus Crataegi, the Cortex Eucommiae, Herba Apocyni veneti, folded parasitic, Herba Bidentis Bipinnatae, Rhizoma Phragmitis, Radix Ilicis Pubescentis and Juncus effcus decoct with water twice, the water yield was not there to be powder to be advisable, decocting time is 2-3 hour for the first time, decocting time is 1-2 hour for the second time, after decocting well, standing 16 hours, filter and extract medicinal liquid,
E, the medicinal liquid of standing 16 hours is mixed with the medicinal liquid extracting in " C " step decoct 2 times, 3 hours for the first time, 2 hours for the second time, with 600 mesh sieves filter, extraction medicinal liquid, standby;
F, the medicinal liquid of " E " step gained is added to PH debugging agent, pH value is adjusted to prescribed limit, the capping of bottling afterwards.
CN201310742754.XA 2013-12-30 2013-12-30 Hemangioma nursing medicament and preparation method thereof Pending CN103736051A (en)

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CN110464774A (en) * 2019-09-17 2019-11-19 河南百年康鑫药业有限公司 A kind of compound hydrochloric acid Propranolol oral solution for treating infantile hemangioma

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104162111A (en) * 2014-08-27 2014-11-26 曲华君 Oral traditional Chinese medicine for treating hemangiomas
CN110464774A (en) * 2019-09-17 2019-11-19 河南百年康鑫药业有限公司 A kind of compound hydrochloric acid Propranolol oral solution for treating infantile hemangioma
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