CN103735830A

CN103735830A - Traditional Chinese medicine composition for treating osteoporosis

Info

Publication number: CN103735830A
Application number: CN201410038001.5A
Authority: CN
Inventors: 陈新
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-01-26
Filing date: 2014-01-26
Publication date: 2014-04-23
Anticipated expiration: 2034-01-26
Also published as: CN103735830B

Abstract

The invention provides a traditional Chinese medicine composition for treating osteoporosis. The traditional Chinese medicine composition is prepared by the following medicaments by weight: 8 parts of prepared rehmannia root, 6 parts of herba epimedii, 3 parts of teasel root, 5 parts of rhizoma cibotii, 4 parts of the fruit of Chinese wolfberry, 5 parts of bighead atractylodes rhizome, 3 parts of rhizoma anemarrhenae, 6 parts of codonopsis pilosula, 5 parts of semen cuscutae, 5 parts of deer-horn glue, 5 parts of fructus psoraleae, 5 parts of rhizoma drynariae, 3 parts of eucommia ulmoides, 4 parts of radix ophiopogonis and 5 parts of oyster. The traditional Chinese medicine composition has an obvious curative effect on osteoporosis.

Description

One is treated osteoporotic Chinese medicine composition

Technical field

the present invention relates to medicine, especially a kind of medicine of the treatment osteoporosis being prepared from by Chinese herbal medicine.

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Background technology

Osteoporosis is a kind of osteopathia that many reasons causes, is that osseous tissue has normal calcification, and calcium salt and substrate are normal ratio, and the metabolic osteopathy that is reduced to feature with unit volume internal skeleton tissue mass becomes.In most osteoporosises, how slow the minimizing of osseous tissue fall ill due to increasing mainly due to bone absorption, very fast individually, with skeleton pain, is easy to fracture for feature, biochemical analysis normal.The visible cortical bone of pathological anatomy is poor, the sparse atrophy of bone trabecula, and osteoid layer is not thick.Women's postmenopausal osteoporotic patients, China about 6000-7,500 ten thousand people left and right, 2.2-2.5 hundred million people left and right, the whole world, there is no at present desirable medicine, primary treatment method has: 1, controversies in hormone replacement in the elderly, need life-time service more than 7-10 years, determined curative effect, but have the severe complications such as 5-10% carcinogenic rate and metrorrhagia; 2, the use of calcium preparation and fluoride preparation, can improve the density of bone, but because not changing the metabolism of bone, increase on the contrary the fragility of bone; 3, the use of phosphate preparation, it can suppress osteoclast activity, but can not promote skeletonization; 4, Chinese patent medicine is as the use of XIANLING GUBAO, and the Chinese medicine preparation of being produced by Guizhou Xian Ling pharmaceutcal corporation, Ltd, is the most representative Chinese patent medicine of current state this disease of internal therapy, but determined curative effect less in this class medicine.

Summary of the invention

in order to solve the problems of the technologies described above, to the invention provides one and treat osteoporotic Chinese medicine composition.

Technical scheme of the present invention is as follows: one is treated osteoporotic Chinese medicine composition, by the medicine of following weight portion, is prepared from: 8 parts, Radix Rehmanniae Preparata, 6 parts of Herba Epimedii, 3 parts of Radix Dipsacis, 5 parts of Rhizoma Cibotii, 4 parts of Fructus Lycii, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts of the Rhizoma Anemarrhenaes, 6 parts of Radix Codonopsis, 5 parts of Semen Cuscutae, 5 parts of Colla cornus cervis, 5 parts of Fructus Psoraleaes, 5 parts of Rhizoma Drynariae, 3 parts of the Cortexs Eucommiae, 4 parts of Radix Ophiopogonis, 5 parts of Concha Ostreaes.

The present invention adopts following preparation method preparation:

Get above each taste, add the water extraction twice of 8 times, 6 times amounts, each 2 hours, merging filtrate, was concentrated to 1g/ml.

clinical data:

1. patient's material

Diagnostic criteria, with reference to " Chinese's osteoporosis suggestion diagnostic criteria (the second original text) ", must possess whole body pain, be that obviously microtrauma can cause fracture, or scheuermann kyphosis deformity, or bone density (BMD) reduces by 2 above persons of standard deviation mainly with lumbar and back pain.

Inclusive criteria 1, there is typical osteoporosis (OP) clinical symptoms, meet OP diagnostic criteria; 2, age person between 45-70 years old; 3,, voluntarily as study subject, signature notice in the know, and energy reception test pharmaceutical dosage form, guarantee completed treatment person.

Exclusion standard 1, there are secondary osteoporosis and other serious complication persons 2 such as hyperparathyroidism, osteomalacia, rheumatoid arthritis, multiple myeloma, present obvious bow-backed deformity, deformity and disability person; 3 suffer from serious cerebrovascular, liver, kidney, lung and hemopoietic system primary disease person; 4, within the observation period course for the treatment of, due to a variety of causes, as go out, residence transfer etc. can not obtain the person of following up a case by regular visits on request; 5, to this drug allergy person or to multi-medicament allergy sufferers; 6, psychosis or patients with Alzheimer disease; 7, duration of test is failed medication or the person of dropping by the wayside in accordance with regulations.

According to above-mentioned standard, choose patient's 100 examples, wherein male 48 examples, female's 52 examples, 50 years old mean age.

2. Therapeutic Method

Use embodiment 1 Chinese medicine to treat for above-mentioned patient, a prescription is potion, and a point morning and evening takes for twice, take 30 days as one course for the treatment of, carries out continuously two courses for the treatment of.

3. criterion of therapeutical effect

Effective: the pain BMD that disappears completely checks and shows that bone density increases: effectively: pain is obviously alleviated, BMD checks that having no bone density declines; Invalid: relatively front with treatment, each side is all without improving

4. result

100 routine patients all meet remarkable standard after treatment.

5. untoward reaction

For 100 routine patients, in therapeutic process, follow middle observation, do not find obvious untoward reaction.

The specific embodiment

Below in conjunction with embodiment, the present invention is further illustrated.

Embodiment 1

By the medicine of following weight portion, be prepared from: 8 parts, Radix Rehmanniae Preparata, 6 parts of Herba Epimedii, 3 parts of Radix Dipsacis, 5 parts of Rhizoma Cibotii, 4 parts of Fructus Lycii, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts of the Rhizoma Anemarrhenaes, 6 parts of Radix Codonopsis, 5 parts of Semen Cuscutae, 5 parts of Colla cornus cervis, 5 parts of Fructus Psoraleaes, 5 parts of Rhizoma Drynariae, 3 parts of the Cortexs Eucommiae, 4 parts of Radix Ophiopogonis, 5 parts of Concha Ostreaes; Get above each taste, add the water extraction twice of 8 times, 6 times amounts, each 2 hours, merging filtrate, was concentrated to 1g/ml.

Claims

1. the osteoporotic Chinese medicine composition for the treatment of, it is characterized in that, by the medicine of following weight portion, be prepared from: 8 parts, Radix Rehmanniae Preparata, 6 parts of Herba Epimedii, 3 parts of Radix Dipsacis, 5 parts of Rhizoma Cibotii, 4 parts of Fructus Lycii, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts of the Rhizoma Anemarrhenaes, 6 parts of Radix Codonopsis, 5 parts of Semen Cuscutae, 5 parts of Colla cornus cervis, 5 parts of Fructus Psoraleaes, 5 parts of Rhizoma Drynariae, 3 parts of the Cortexs Eucommiae, 4 parts of Radix Ophiopogonis, 5 parts of Concha Ostreaes.