CN103735739A - Slimming composition and preparation method thereof - Google Patents
Slimming composition and preparation method thereof Download PDFInfo
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- CN103735739A CN103735739A CN201310741475.1A CN201310741475A CN103735739A CN 103735739 A CN103735739 A CN 103735739A CN 201310741475 A CN201310741475 A CN 201310741475A CN 103735739 A CN103735739 A CN 103735739A
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Abstract
The invention provides a slimming composition. The effective components of the composition comprise a cereus extract, a green tea extract and a guarana extract. The composition is compounded from the cereus extract, green tea extract and guarana extract, wherein the cereus extract can regulate the activity of lipase, promote excessive fat to be quickly decomposed, and effectively prevent the fat from being absorbed by the intestinal tract, thereby achieving the slimming effect; the green tea extract has the functions of lowering and consuming the enzyme activity, reducing the food intake and energy absorption and increasing the lipolysis and metabolism; the guarana extract can increase the rate of metabolism, enhance the energy consumption and stimulate the lipolysis; and the three extracts, which are proportionally compounded, can obviously enhance the slimming effect and have a synergic action.
Description
Technical field
The present invention relates to field of health care products, specifically, relate to a kind of Weight reducing compound and preparation method thereof.
Background technology
In recent years, along with improving constantly of living standard, people more and more pay attention to the health of self, are improved health and are accepted gradually, and become a kind of trend by health food.Along with the raising gradually of people's living standard, food type and food supply are all very abundant.The diet be in easy circumstances, allegro life causing is irregular, lacks motion etc., makes the absorption of body self-energy be greater than consumption, athero, and adipose cell increases, and the fat of health surpasses normal level, thereby causes obesity.Obesity is a kind of metabolic chronic disease, by obesity, can cause various diseases, as hypertension, hyperlipidemia, diabetes, coronary heart disease etc.These diseases are being engulfed people's health just gradually, brought very big impact to work and life, and the fat number of China are increasing with surprising rapidity, and problem of obesity can not be ignored.
At present, all kinds of diet food on market are multifarious, food, medicine, health product etc.Most products is to take appetite-suppressing, or takes the methods such as diarrhoea to reach the object of fat-reducing.Though some produces effect, also exist very large side effect, to healthy, cause damage.
Summary of the invention
The object of this invention is to provide and a kind ofly can effectively suppress fat and energy is taken in, excitor nerve promotes lipid metabolism, thereby reach, nature is controlled and the Weight reducing compound of attenuating body weight object.
Another object of the present invention is to provide the preparation method of described Weight reducing compound.
In order to realize the object of the invention, a kind of Weight reducing compound of the present invention, the effective ingredient of described compositions comprises Radix et Caulis Opuntiae Dillenii extract, green tea extract and Paullina Cupana extract.
In described compositions, each effective ingredient by weight: 100～1000 parts of 500～1500 parts of Radix et Caulis Opuntiae Dillenii extracts, 50～250 parts of green tea extracts and Paullina Cupana extracts.
Preferably, in described compositions, each effective ingredient is by weight: 800～1200 parts of Radix et Caulis Opuntiae Dillenii extracts, 100～150 parts of green tea extracts, 600～800 parts of Paullina Cupana extracts.
Wherein, described weight portion can be the known unit of weights of field of medicaments such as μ g, mg, g, kg.
Described Radix et Caulis Opuntiae Dillenii extract extracts from Radix et Caulis Opuntiae Dillenii root and stem, and the weight ratio of root and stem is 20:1.Extracting method is: to the water extraction 2 times that adds 8 times of weight in root and stem, and each 1.5 hours, merge extractive liquid,, concentrated, spraying is dry, obtains Radix et Caulis Opuntiae Dillenii extract.
In described green tea extract, contain the nutgall catechin gallic acid ester (EGCG) of 70w/w%.Extracting method is: to 80% ethanol extraction 2 times that adds 5 times of weight in dry green tea, each 1.5 hours, merge extractive liquid,, reclaimed ethanol, vacuum concentration, and spraying is dry, obtains green tea extract.
Described Paullina Cupana extract is to extract the Paullina Cupana bean producing from Brazil, containing the natural caffeine of 10w/w%.Extracting method is: in Paullina Cupana bean, add 6 times of weight, 75% ethanol extraction 2 times, each 2 hours, merge extractive liquid,, reclaimed ethanol, vacuum concentration, and spraying is dry, obtains Paullina Cupana extract.
In Weight reducing compound provided by the invention, also comprise pharmaceutically acceptable carrier or diluent.For example, in described compositions, each composition is by weight: 500～1500 parts of Radix et Caulis Opuntiae Dillenii extracts, 50～250 parts of green tea extracts, 100～1000 parts of Paullina Cupana extracts and pharmaceutically acceptable carrier 100-20000.
Described pharmaceutically acceptable carrier or diluent are selected from one or more in xylitol, Sorbitol, hydroxyl isomaltulose, isomaltulose, mannitol, ethanol, microcrystalline Cellulose, lactose, starch, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose or magnesium stearate etc.
Described Weight reducing compound can be prepared into solid preparation or liquid preparation, and solid preparation comprises, such as tablet, capsule, granule etc.
In Weight reducing compound formula provided by the invention:
Radix et Caulis Opuntiae Dillenii extract is the root of Cactaeous plants Radix et Caulis Opuntiae Dillenii Opuntia dillenii Haw and the extract of stem, has the effect of fat-reducing, blood sugar lowering, antibacterial, antiinflammatory.In Radix et Caulis Opuntiae Dillenii, contain abundant hydroxymalonic acid, inhibited to fatty growth; Radix et Caulis Opuntiae Dillenii is containing triterpenoid saponin, triterpene is the necessary material of human body, they can directly regulate human body Secretion and regulate the activity of lipase, promote that superabundant fats decomposes rapidly, and can effectively prevent that fat is by intestinal absorption, suppress fat synthetic in liver, antagonism cholesterol, in the deposition of blood vessel, can lose weight by easy stages.
Green tea extract is the polyphenols extracting from natural green tea, and wherein catechin component content is more, and particularly the content of nutgall catechin gallic acid ester (EGCG) reaches 70%.EGCG is the chief component composition of Green Tea Polyphenols, is also the main component of green tea catechins class.The fat-reducing mechanism of its functional component EGCG it be unclear that, and has molecule experiment and the prompting of cell experiment result of study, and EGCG brings into play antiobesity action by following approach: (1) reduces consumption enzyme activity, reduces the absorption of food intake and energy; (2) increase steatolysis, oxidation and burning; (3) regulate the expression of lipoprotein; (4) reduce the quantity of front adipose cell and adipose cell, make weight loss.There is bibliographical information, the moderate obese patient (body index 25-32kg/m2) of take is object of study, experimenter takes 4 of green tea extract capsules every day, and (wherein dosage is counted 375mg with catechin, with EGCG, count 270mg) take continuously after 3 months, lost weight 4.6%, waistline has reduced 4.48%.
Paullina Cupana (Guarana) is a kind of wild certain kind of berries of Amazon area special product, is heat energy combustion fat supplement, includes natural Caffeine, vitamin, unsaponifiable matter and tannin, and abundant alkaloid, tannin, protein etc.The caffeine that Paullina Cupana seed and root contain can keep the human body mental status, is specially adapted to deal with modern society's life, and research shows, the excited people's of a small amount of caffeine energy nerve, there is the effect of burning body fat, make people keep the good mental status, therefore there is the effect of fat-reducing.
The present invention further provides the preparation side of described compositions: take in proportion Radix et Caulis Opuntiae Dillenii extract, green tea extract and Paullina Cupana extract, sieve, mix, obtain.
Weight reducing compound of the present invention can effectively suppress fat and energy is taken in, and excitor nerve promotes lipid metabolism, thereby reaches the object that body weight was controlled and lowered to nature.
Compositions for losing weight of the present invention, Radix et Caulis Opuntiae Dillenii extract, green tea extract and Paullina Cupana extract are carried out composite in specific proportions, wherein, Radix et Caulis Opuntiae Dillenii extract regulates the activity of lipase, promote that superabundant fats decomposes rapidly, and can effectively prevent that fat is in intestinal absorption, thereby reach fat-reducing effect; Green tea extract has the consumption of reduction enzyme activity, reduces the absorption of food intake and energy, has the effect that increases steatolysis and metabolism simultaneously; Paullina Cupana extract increases rate of metabolism, can increase energy expenditure and stimulate steatolysis, and it is composite that three kinds of extracts carry out by a certain percentage, can significantly increase fat-reducing effect, has synergistic function.
The specific embodiment
Following examples are used for illustrating the present invention, but are not used for limiting the scope of the invention.If do not specialize, the conventional means that in embodiment, technological means used is well known to those skilled in the art, the raw materials used commercial goods that is.
The Radix et Caulis Opuntiae Dillenii extract who relates in following examples and green tea extract are purchased from Jiahe, Shaanxi plant Chemical Co., Ltd., and Paullina Cupana extract is purchased from the illustrious and influential International Trading Company Ltd in Dalian.
Embodiment 1 Weight reducing compound capsule
1, prescription: Radix et Caulis Opuntiae Dillenii extract 500g, green tea extract 250g, Paullina Cupana extract 1000g, starch 250g.
2, preparation technology
1) according to prescription, take Radix et Caulis Opuntiae Dillenii extract, green tea extract, Paullina Cupana extract and cross respectively 40 mesh sieves, standby;
2) according to prescription, take starch, above-mentioned supplementary material, by the equivalent method mix homogeneously that progressively increases, is poured in capsule-filling mould, fill capsule, polishing, subpackage, obtains 5000.
3, specification: every 400mg, containing Radix et Caulis Opuntiae Dillenii extract 0.1g, green tea extract 0.05g, Paullina Cupana extract 0.2g.
Embodiment 2 Weight reducing compound granules
1, prescription: Radix et Caulis Opuntiae Dillenii extract 1500g, green tea extract 50g, Paullina Cupana extract 100g, hydroxyl isomaltulose 3350g.
2, preparation technology
1) according to prescription, take Radix et Caulis Opuntiae Dillenii extract, green tea extract, Paullina Cupana extract and cross respectively 40 mesh sieves, standby;
2) according to prescription, take hydroxyl isomaltulose; by above-mentioned supplementary material by the equivalent method mix homogeneously that progressively increases; use 50% ethanol as binding agent, soft material processed, by above-mentioned soft material granulation in the oscillating granulator of 14 eye mesh screens; granule is inserted in multi-functional boiling drier; 50 ℃ of airpillow-dry approximately 40 minutes, control pellet moisture 5%, then granulate; subpackage, obtains 1000 bags.
3, specification: every bag of 5g, containing Radix et Caulis Opuntiae Dillenii extract 1.5g, green tea extract 0.05g, Paullina Cupana extract 0.1g.
Embodiment 3 Weight reducing compound tablets
1, prescription: Radix et Caulis Opuntiae Dillenii extract 800g, green tea extract 150g, Paullina Cupana extract 800g, starch 220g, lactose 1000g, magnesium stearate 30g.
2, preparation technology
1) according to prescription, take Radix et Caulis Opuntiae Dillenii extract 800g, green tea extract 150, Paullina Cupana extract 800g, standby;
2) according to recipe quantity, take starch, lactose, by the equivalent method mix homogeneously that progressively increases, use 50% ethanol as binding agent above-mentioned supplementary material; soft material processed, by above-mentioned soft material granulation in the oscillating granulator of 14 eye mesh screens, inserts granule in multi-functional boiling drier; 50 ℃ of airpillow-dry approximately 40 minutes, control pellet moisture 5%, granulate; then in granule, add magnesium stearate 20g; mix homogeneously, tabletting, film coating; subpackage, obtains 5000.
3, specification: every 0.6g, containing Radix et Caulis Opuntiae Dillenii extract 0.16g, green tea extract 0.03g, Paullina Cupana extract 0.16g.
Embodiment 4 Weight reducing compound capsules
1, prescription: Radix et Caulis Opuntiae Dillenii extract 1200g, green tea extract 100g, Paullina Cupana extract 600g, starch 640g.
2, preparation technology
1) according to prescription, take Radix et Caulis Opuntiae Dillenii extract 1200g, green tea extract 100, Paullina Cupana extract 600g, cross respectively 40 mesh sieves, standby;
2) according to prescription, take starch, above-mentioned supplementary material, according to the equivalent method mix homogeneously that progressively increases, is poured in capsule-filling mould, fill capsule, polishing, subpackage, obtains 5000.
3, specification: every 400mg, containing Radix et Caulis Opuntiae Dillenii extract 0.24g, green tea extract 0.02g, Paullina Cupana extract 0.12g.
Embodiment 5 Weight reducing compound capsules
1, prescription: Radix et Caulis Opuntiae Dillenii extract 1000g, green tea extract 120g, Paullina Cupana extract 500g, starch 380g.
2, preparation technology
1) according to prescription, take Radix et Caulis Opuntiae Dillenii extract 1000g, green tea extract 120, Paullina Cupana extract 500g, cross respectively 40 mesh sieves, standby;
2) according to prescription, take starch, above-mentioned supplementary material, according to the equivalent method mix homogeneously that progressively increases, is poured in capsule-filling mould, fill capsule, polishing, subpackage, obtains 5000.
3, specification: every 400mg, containing Radix et Caulis Opuntiae Dillenii extract 0.2g, green tea extract 0.024g, Paullina Cupana extract 0.1g.
The human experimentation of embodiment 6 Weight reducing compounds
1, experimental subject and method
1.1 experimental subject
This is tested whole experimenters and before experiment, carries out respectively constitutional index assessment and be obese people, male 40 examples in 84 routine experimenters, female's 44 examples; Age is between 18-45 year, year mean age (30.7 ± 6.5).
1.2 experimental technique
Grouping: 84 experimenters are divided into six groups at random, negative control group (N=12), positive control one group of (N=12), positive control two groups of (N=12), positive control three groups of (N=12), experiment one group of (N=12), experiment two groups of (N=12) and three groups (N=12) of experiment.Negative control group is taken placebo, 5/day; One group of positive control is taken Radix et Caulis Opuntiae Dillenii capsule, 5/day (every containing Radix et Caulis Opuntiae Dillenii extract 0.2g); Two groups of positive controls are taken green tea extract, 5/day (every containing green tea extract 0.3g); Three groups of positive controls are taken Paullina Cupana extract, and 5/day (every containing Paullina Cupana extract 0.1g), test one group and take the Weight reducing compound group of preparing in the embodiment of the present invention 5,5/day; Test two groups of Weight reducing compounds of taking preparation in the embodiment of the present invention 3,5/day; Test 1 bag/day of three groups of Weight reducing compound of taking in the embodiment of the present invention 2 preparation.Take continuously according to the method described above 8 weeks.Whole experimental session, does not keep on a diet, and deliberately do not increase motion, and taboo takes other diet food and medicine.
1.3 test index
1.3.1 body composition test: before experiment and adopt weekly the body weight of DX200 super strong type body composition test instrument test subject, body fat percentage, body-mass index after experiment.
1.4 data statistics
The data obtained is processed with Excel, adopts single blind method and t check to carry out statistical analysis to test data, with mean ± SD, represents.
2, experimental result and analysis
2.1 body composition analysis results
2.1.1 subject re-detection result before and after testing
Experimenter's body weight situation of change before and after table 1 experiment
Note: with take before compare, * P<0.05, * * P<0.01; Compare with one group of positive control,
#p<0.05; Compare with two groups of positive controls,
aMP.AMp.Ampp<0.05; Compare ^P<0.05 with three groups of positive controls.
As can be seen from Table 1; compare with the body weight before experiment; after one group of positive control, two groups of positive controls, three groups of positive controls, one group of experiment, two groups of experiments and three groups of experiments of experiment, body weight all have different reductions, one group of positive control, two groups of positive controls and three groups of body weight of positive control significantly decline (P<0.05); Test one group, two groups of experiments and the experiment body weight of three groups extremely significantly decline (P<0.01).
Compare with one group of positive control, test the weight loss obvious (P<0.05) of a group, two groups, three groups.
Compare with two groups of positive controls, test one group, the weight loss of two groups of experiments, three groups of experiments obviously (P<0.05).
Compare with three groups of positive controls, test one group, the weight loss of two groups of experiments, three groups of experiments obviously (P<0.05).
2.1.2 body fat percentage testing result before and after testing
Table 2 experimenter body fat percentage testing result
Note: with take before compare, * P<0.05, * * P<0.01; Compare with one group of positive control,
#p<0.05; Compare with two groups of positive controls,
aMP.AMp.Ampp<0.05; Compare ^P<0.05 with three groups of positive controls.
As can be seen from Table 2, compare with the body fat percentage before experiment, after negative control group, one group of positive control, two groups of positive controls, three groups of positive controls, one group of experiment, two groups of experiments and three groups of experiments of experiment, body fat percentages all have different reductions, one group of positive control, two groups of positive controls and three groups of body fat percentages of positive control significantly decline (P<0.05); Test one group, two groups of experiments and the experiment body fat percentage of three groups extremely significantly decline (P<0.01).
Compare with one group of positive control, test the body fat decline obvious (P<0.05) of one group, two groups, three groups.
Compare with two groups of positive controls, test one group, the body fat of two groups of experiments, three groups of experiments decline obviously (P<0.05).
Compare with three groups of positive controls, test one group, the body fat of two groups of experiments, three groups of experiments decline obviously (P<0.05).
3, conclusion
In compositions of the present invention, Radix et Caulis Opuntiae Dillenii extract, green tea extract and Paullina Cupana extract carry out composite in specific proportions, wherein, Radix et Caulis Opuntiae Dillenii extract regulates the activity of lipase, promotes that superabundant fats decomposes rapidly, and can effectively prevent that fat is in intestinal absorption, thereby reach fat-reducing effect; Green tea extract has the consumption of reduction enzyme activity, reduces the absorption of food intake and energy, has the effect that increases steatolysis and metabolism simultaneously.Paullina Cupana extract increases rate of metabolism, can increase energy expenditure and stimulate steatolysis, and three kinds of extracts are arranged in pairs or groups by a certain percentage, can significantly increase fat-reducing effect, have synergistic function.
In the present embodiment, with ratio before experiment, the amplitude that experimental group is lost weight is greater than one group of positive control, two groups and three groups, body fat percentage is utmost point significance and declines, illustrate that experimenter takes Weight reducing compound of the present invention at the slimming fat that reduces simultaneously, body fat percentage declines, and then reaches the object of fat-reducing, has synergistic function.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements, all belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (10)
1. a Weight reducing compound, is characterized in that, the effective ingredient of described compositions comprises Radix et Caulis Opuntiae Dillenii extract, green tea extract and Paullina Cupana extract.
2. compositions according to claim 1, is characterized in that, in described compositions, each effective ingredient by weight: 100～1000 parts of 500～1500 parts of Radix et Caulis Opuntiae Dillenii extracts, 50～250 parts of green tea extracts and Paullina Cupana extracts.
3. compositions according to claim 2, is characterized in that, in described compositions, each effective ingredient by weight: 800～1200 parts of Radix et Caulis Opuntiae Dillenii extracts, 100～150 parts of green tea extracts, 600～800 parts of Paullina Cupana extracts.
4. compositions according to claim 1, is characterized in that, described Radix et Caulis Opuntiae Dillenii extract extracts from Radix et Caulis Opuntiae Dillenii root and stem, and the weight ratio of root and stem is 20:1; Extracting method is: to the water extraction 2 times that adds 8 times of weight in root and stem, and each 1.5 hours, merge extractive liquid,, concentrated, spraying is dry, obtains Radix et Caulis Opuntiae Dillenii extract.
5. compositions according to claim 1, is characterized in that, contains the nutgall catechin gallic acid ester of 70w/w% in described green tea extract; Extracting method is: to 80% ethanol extraction 2 times that adds 5 times of weight in green tea, each 1.5 hours, merge extractive liquid,, reclaimed ethanol, vacuum concentration, and spraying is dry, obtains green tea extract.
6. compositions according to claim 1, is characterized in that, described Paullina Cupana extract is to extract from Paullina Cupana bean, containing the natural caffeine of 10w/w%; Extracting method is: in Paullina Cupana bean, add 6 times of weight, 75% ethanol extraction 2 times, each 2 hours, merge extractive liquid,, reclaimed ethanol, vacuum concentration, and spraying is dry, obtains Paullina Cupana extract.
7. compositions according to claim 1, is characterized in that, described compositions also comprises pharmaceutically acceptable carrier or diluent.
8. compositions according to claim 7, it is characterized in that, described pharmaceutically acceptable carrier or diluent are selected from one or more in xylitol, Sorbitol, hydroxyl isomaltulose, isomaltulose, mannitol, ethanol, microcrystalline Cellulose, lactose, starch, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose or magnesium stearate.
9. according to the compositions described in claim 1-8 any one, it is characterized in that, described compositions is tablet, capsule or granule.
10. the preparation method of compositions described in claim 1-9 any one, is characterized in that, takes in proportion Radix et Caulis Opuntiae Dillenii extract, green tea extract and Paullina Cupana extract, sieves, and mixes, and obtains.
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947962A (en) * | 2014-05-09 | 2014-07-30 | 上海盛世中侬农业科技发展有限公司 | Weight-losing food |
| CN104366647A (en) * | 2014-10-20 | 2015-02-25 | 北京康比特体育科技股份有限公司 | Composition capable of enhancing durability and relieving fatigue and preparation method of composition |
| CN104397697A (en) * | 2014-12-02 | 2015-03-11 | 张满锦 | Weight-losing guarana oral liquid |
| CN104547274A (en) * | 2014-12-19 | 2015-04-29 | 北京康比特体育科技股份有限公司 | Weight losing composition containing citrus aurantium extract and preparation of weight losing composition |
| CN105410927A (en) * | 2015-10-30 | 2016-03-23 | 郭长合 | Plant-source food capable of reducing weight and preparation method of plant-source food |
| CN105520880A (en) * | 2016-01-20 | 2016-04-27 | 广州丹奇日用化工厂有限公司 | Weight-reducing cosmetic composition |
| CN105685288A (en) * | 2016-01-20 | 2016-06-22 | 广州丹奇日用化工厂有限公司 | Tea leaf composition and application of tea leaf composition |
| CN114391653A (en) * | 2021-12-24 | 2022-04-26 | 山东捷晶生物科技有限公司 | Sports nutrition tablet for losing weight and preparation method thereof |
| CN115039878A (en) * | 2021-03-09 | 2022-09-13 | 仙乐健康科技股份有限公司 | Composition for regulating fat metabolism function |
| CN115969045A (en) * | 2021-10-14 | 2023-04-18 | 南京盛德生物科技研究院有限公司 | Composition with weight health management function and preparation method and application thereof |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103947962A (en) * | 2014-05-09 | 2014-07-30 | 上海盛世中侬农业科技发展有限公司 | Weight-losing food |
| CN103947962B (en) * | 2014-05-09 | 2015-10-28 | 上海盛世中侬农业科技发展有限公司 | A kind of diet food |
| CN104366647B (en) * | 2014-10-20 | 2016-09-28 | 北京康比特体育科技股份有限公司 | A kind of stamina intensifying, composition for relieving fatigue and preparation method thereof |
| CN104366647A (en) * | 2014-10-20 | 2015-02-25 | 北京康比特体育科技股份有限公司 | Composition capable of enhancing durability and relieving fatigue and preparation method of composition |
| CN104397697A (en) * | 2014-12-02 | 2015-03-11 | 张满锦 | Weight-losing guarana oral liquid |
| CN104547274B (en) * | 2014-12-19 | 2018-09-25 | 北京康比特体育科技股份有限公司 | Weight reducing compound containing Bitter Orang P.E and its preparation |
| CN104547274A (en) * | 2014-12-19 | 2015-04-29 | 北京康比特体育科技股份有限公司 | Weight losing composition containing citrus aurantium extract and preparation of weight losing composition |
| CN105410927A (en) * | 2015-10-30 | 2016-03-23 | 郭长合 | Plant-source food capable of reducing weight and preparation method of plant-source food |
| CN105520880A (en) * | 2016-01-20 | 2016-04-27 | 广州丹奇日用化工厂有限公司 | Weight-reducing cosmetic composition |
| CN105685288A (en) * | 2016-01-20 | 2016-06-22 | 广州丹奇日用化工厂有限公司 | Tea leaf composition and application of tea leaf composition |
| CN115039878A (en) * | 2021-03-09 | 2022-09-13 | 仙乐健康科技股份有限公司 | Composition for regulating fat metabolism function |
| CN115039878B (en) * | 2021-03-09 | 2024-01-05 | 仙乐健康科技股份有限公司 | Composition for regulating fat metabolism |
| CN115969045A (en) * | 2021-10-14 | 2023-04-18 | 南京盛德生物科技研究院有限公司 | Composition with weight health management function and preparation method and application thereof |
| CN114391653A (en) * | 2021-12-24 | 2022-04-26 | 山东捷晶生物科技有限公司 | Sports nutrition tablet for losing weight and preparation method thereof |
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Application publication date: 20140423 |