CN103735248B - A kind of near infrared spectroscopy and electrode joint-detection device - Google Patents
A kind of near infrared spectroscopy and electrode joint-detection device Download PDFInfo
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- CN103735248B CN103735248B CN201310733760.9A CN201310733760A CN103735248B CN 103735248 B CN103735248 B CN 103735248B CN 201310733760 A CN201310733760 A CN 201310733760A CN 103735248 B CN103735248 B CN 103735248B
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Abstract
The present invention relates to a kind of near infrared spectroscopy and electrode joint-detection device.This device is divided into elastic inner layer and non-resilient skin.Elastic inner layer is adapted to different detected physiological site shapes, and is mounted with the electrode according to standard setting arrangement.Non-resilient skin is provided with the near-infrared probe that spacing is fixing.Near-infrared probe by probe positioner, fibre holder, and non-metal elastic pressure cap composition.Probe positioner is fixed on non-resilient skin, for positioning probe position.Have through hole in the middle of probe positioner, diameter, slightly larger than fibre holder, makes fibre holder be free to slide wherein.Fibre holder is cylindric part, and centre has through hole and is used for grip optical fiber.Elastic pressing cap is used for applying elastic pressure to optical fiber.The present invention proposes one can meet electrode standard setting and near-infrared light source-detector constant spacing demand simultaneously, simple, practical, near infrared spectroscopy compatible under nuclear-magnetism and electrode joint-detection device.
Description
Technical field
The present invention relates to biological tissue's functional activity non-destructive detecting device field, particularly relate to a kind of near infrared spectroscopy and electrode joint-detection device.
Background technology
The tissue optical parameter that biological tissue's spectral measurement can be monitored with physiological activity changes, and bioelectrical signals measures the biological electric discharging process can monitored with physiological activity.Spectrum and electric signal measurement are carried out to biological tissue simultaneously and can obtain more comprehensively physiologic information, better cognitive biological tissue functional activity mechanism.
For brain function monitoring, the normal electroencephalogram technology adopted based on neuroelectricity activity traditionally.In recent years, the near infrared spectroscopy measuring hematodinamics response also causes people more and more to pay close attention to.
Brain electricity detects brain function activity by measuring electroneurographic signal.At present for mankind's EEG research, be mainly divided into spontaneous brain electricity figure and event-related EEG two kinds of research meanses.The advantage of brain power technology is that temporal resolution is high, but due to the disperse characteristic of the signal of telecommunication, brain electricity is more difficult for the contrast locating of brain function activity.Near infrared spectroscopy utilizes the characteristic of near infrared band biological organism optical window.When using the illumination of this wave band to penetrate human brain, part light can enter cerebral tissue, and is scattered out brain.Be scattered the change information that the light of returning carries hemodynamic parameter, the detector of service range light source certain distance receives the optical signal from brain outgoing, just indirectly can obtain the functional activity situation of brain.The advantage of near infrared spectroscopy can carry out other space orientation of Centimeter Level to cerebration.
Can in conjunction with the advantage of two kinds of technology in Time and place resolution by brain electricity and near infrared spectroscopy conbined usage, and can the contact between the electroneurographic signal simultaneously gathered and hematodinamics signal be analyzed, better understand the working mechanism of brain.But, as the critical component of two kinds of technical tie-ups, the current still important technological problems of Collect jointly device.Xu Baolei etc. [application number 201110216299.0] disclose the device of a kind of brain electricity and near infrared spectroscopy Collect jointly brain signal, the flexible material of same covering scalp is fixed with electrode for encephalograms and near-infrared probe, and wherein near-infrared probe adopts spring design to keep the abundant contact of probe fall skin.This design cannot meet the requirement using brain electrode standard setting and ensure fixing near-infrared light source-detector pitch simultaneously.Use the positioning of electrode of standard, device is wanted to adapt to different head dummy, device is needed to have elasticity, can stretch, but the distance between near-infrared probe so just can be caused to change, and light source and detector pitch are the key factors affecting near infrared spectroscopy investigation depth, be generally all pre-set fixed value, as 3cm.And elastic device is poor for the fiber support with constant weight, increase the difficulty that device is worn, poor practicability.Ensure that near-infrared light source and detector pitch fix requirement, device materials needs for non-elastic material, non-stretchable, but like this just can not adapt to different head dummys, cannot ensure the standard setting of electrode for encephalograms.Use the near-infrared probe part of metal spring complicated in addition in this patent, and incompatible for the research of syncaryon mr imaging technique.
Summary of the invention
Simultaneously technical problem to be solved by this invention proposes one to meet electrode standard setting and near-infrared light source-detector constant spacing demand, simple, practical, near infrared spectroscopy compatible under nuclear-magnetism and electrode joint-detection device.
For solving the problems of the technologies described above, the present invention proposes a kind of near infrared spectroscopy and electrode joint-detection device, device comprises the elastic inner layer loading electrode and the non-resilient skin loading near-infrared probe.
Described elastic inner layer adapts to the individual difference of physiological site shape, and is mounted with the electrode according to standard setting arrangement, meets the demand of electrode standard setting.Electrode standard positioning system selects brain electricity 10-10,10-20,10-20 expanding system or other electrode standard positioning systems.
Described elastic inner layer has optical fiber by the first hole, make can touch physiological site from outer field optical fiber.
Described elastic inner layer optical fiber is greater than fibre diameter by the first hole, ensures when because adapting to physiological site shape, optical fiber still can pass through optic fibre end by during the first hole off-centring.
Described elastic inner layer can by elastic woven material, and gum elastic or other elastomeric materials are made.
Described non-resilient skin can by plastics, and non-resilient rubber, the non-elastic materials such as thermoplastic material are made.
Described non-resilient skin is provided with the near-infrared probe that spacing is fixing, near-infrared probe is installed luminous source optical fiber or detection optical fiber, meet the demand of near-infrared light source-detector constant spacing.
Described non-resilient skin has good enabling capabilities, can support the fibre-optical probe with constant weight, wears conveniently.Optic fibre end contacts physiological site by the optical fiber on described elastic inner layer by the first hole.
Described non-resilient skin has electrode and exposes the second hole, the electrode on elastic inner layer is come out, for injecting conductive paste and adjustment electrode.
Electrode on described non-resilient skin exposes the second hole and is greater than electrode diameter, ensures still can by electrode expose hole because adapting to physiological site shape during off-centring when electrode and be exposed to outside.
Electrode arrangement straggly on described near-infrared probe and elastic inner layer, spreads all over whole physiological site region to be detected, and near-infrared probe relies on the electrode identification physiological site of standard setting arrangement.
Described non-resilient skin and described elastic inner layer link together at device edge and the middle elastomeric material that uses, and have certain activity independence and position definitiveness between assurance device is two-layer
Described near-infrared probe comprises probe positioner, fibre holder, elastic pressing cap three assembly.
Described probe positioner is fixed on described non-resilient skin, for positioning probe position.
There is through hole, for placing described fibre holder in the middle of described probe positioner.
Described fibre holder is cylindric part, and centre has through hole and is used for grip optical fiber.
Described fibre holder external diameter is slightly less than described probe positioner through-hole diameter, freely can pass through in described probe positioner through hole.
The two ends of described elastic pressing cap are fixed on described probe positioner both sides, or are fixed on the described non-resilient skin of described probe positioner both sides.
Be placed in described probe positioner through hole after the elbow optical fiber that described fibre holder clamping near infrared spectroscopy often adopts, described elastic pressing cap mid portion is pressed in optical fiber elbow.
Described near-infrared probe three parts use rubber, and latex or other non-metallic elastic materials manufacture.Compatible under realizing the nuclear magnetic resonance, NMR of probe.
Good effect of the present invention is, near infrared spectroscopy and electrode integrated apparatus realize wearing of electrode and near-infrared probe simultaneously, realize two kinds of technical tie-ups to measure, convenient, fast, practicality, particularly solves the problem that existing near infrared spectroscopy and electrode joint-detection device can not meet electrode standard setting and near-infrared light source-detector constant spacing demand simultaneously.Described fibre holder is free to slide design and the design of described elastic pressing cap and ensure that fully contacting and wearing comfort of fiber end face and physiological site to be detected in described probe positioner through hole.Described near-infrared probe is made up of three simple parts of structure, and join the described non-resilient skin good with supportive, processing ease, practicality is good, installs simple.Described near-infrared probe makes upper technique simply in addition, and minimum a kind of technique of need can produce three parts, is easy to large-scale production.And owing to using nonmetallic materials completely, this device is near infrared spectroscopy, and electrode, still can use in the research of NMR (Nuclear Magnetic Resonance)-imaging three kinds of technical tie-ups.
Accompanying drawing explanation
Below in conjunction with the drawings and specific embodiments, technical scheme of the present invention is further described in detail.
Fig. 1 is the probe positioner forming near-infrared probe, fibre holder, elastic pressing cap three assembly schematic diagram.
Fig. 2 is near-infrared probe work front view.
Fig. 3 is near-infrared probe work left view.
The structural representation of Fig. 4 near infrared spectroscopy and electrode joint-detection device.
Detailed description of the invention
What Fig. 1 showed is the probe positioner 1 forming near-infrared probe, fibre holder 2, elastic pressing cap 3 three assembly schematic diagram.The through hole of probe positioner 1 is used for fibre holder 2 and is free to slide, and the through hole of fibre holder 2 is used for grip optical fiber, and elastic pressing cap 3 is for applying elastic pressure to optical fiber.
What Fig. 2 and Fig. 3 showed is use three parts in Fig. 1 to add the near-infrared probe operating diagram that the elbow optical fiber 5 that non-resilient outer 4 and near infrared spectroscopy of device are commonly used is formed.Probe positioner 1 is fixed on non-resilient outer 4, fibre holder 2 is put in probe positioner 1 through hole after clamping elbow optical fiber 5, again elastic pressing cap 3 is covered in the corner of elbow optical fiber 5, the two ends of elastic pressing cap 3 are fixed on probe positioner 1 both sides, or are fixed on non-resilient outer 4 of probe positioner 1 both sides.Fig. 2 is front view, and Fig. 3 is left view.This design ensure that fully contacting and wearing comfort of fiber end face and physiological site.And this probe designs has production technology simply, install simple, the advantages such as NMR (Nuclear Magnetic Resonance)-imaging is compatible.
What Fig. 4 showed is the structural representation of near infrared spectroscopy and electrode joint-detection device.Near-infrared probe needs the spacing with fixing to be arranged on non-resilient outer 4, according to electrode standard positioning system installing electrodes 7 on elastic inner layer 6 according to measuring.Elastic inner layer 6 has optical fiber by the first hole 8, thus make optical fiber 5 termination can with physiological site good contact.Optical fiber adapts to the displacement because physiological site change of shape causes by the diameter that the diameter of the first hole 8 is greater than optical fiber 5.There is on non-resilient outer 4 electrode and expose the second hole 9, for injecting conductive paste and adjustment to electrode 7.The diameter that the diameter that electrode exposes the second hole 9 is greater than electrode 7 adapts to the displacement because physiological site change of shape causes.Thisly comprise elastic inner layer 6 and the non-resilient apparatus structure of outer 4 both can adapt to physiological site shape individual variation, thus make electrode standard setting need to be met, can ensure that again near-infrared light source-detector pitch keeps fixing, can not change along with physiological site shape individual variation.
The present invention specifically implements can have various ways, below in one embodiment for example is described.
Embodiment: for head measurement, use the elastic inner layer of elastic woven material producing device, elastic inner layer is provided with silver/silver chloride sintered electrode, brain electrode is located according to international 10-20 system.Use the non-resilient skin of heat-stabilized wood flitch producing device.The rubber of different hardness is used to produce the probe positioner of near-infrared probe, fibre holder, elastic pressing cap three kinds of parts.Probe positioner outer wall position on the lower side processes the locating hole that a circle groove is accomplished fluently in advance for being stuck in non-resilient skin.Fibre holder through-hole diameter is slightly less than fibre external diameters, clamps optical fiber by caoutchouc elasticity extruding force.Fibre holder external diameter is slightly less than probe positioner through-hole diameter, and fibre holder puts into probe positioner through hole after having clamped optical fiber.The two ends of elastic pressing cap use super glue to be bonded on the non-resilient skin of probe positioner both sides, and middle part is covered in optical fiber elbow.According to near-infrared probe and electrode for encephalograms arrangement, on elastic inner layer and non-resilient skin, process optical fiber respectively and expose the second hole by the first hole and electrode.
By changing the elastic inner layer loading electrode and the stiff outer profile of loading near-infrared probe, the present invention may be used for equally to leg, and arm and other physiological site carry out the signal of telecommunication and spectral technique combined measurement.
It should be noted last that, above detailed description of the invention is only in order to illustrate technical scheme of the present invention and unrestricted, although with reference to preferred embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that, can modify to technical scheme of the present invention or equivalent replacement, and not departing from the spirit and scope of technical solution of the present invention, it all should be encompassed in the middle of right of the present invention.
Claims (11)
1. a near infrared spectroscopy and electrode joint-detection device, it is characterized in that, comprise elastic inner layer and non-resilient skin, described elastic inner layer is adapted to detection site shape, and the electrode be mounted with according to standard positioning system arrangement, described non-resilient skin is provided with the near-infrared probe meeting near-infrared light source-detector constant spacing requirement, described near-infrared probe loads luminous source optical fiber or detection optical fiber; Described elastic inner layer is provided with the first hole, described luminous source optical fiber or detection optical fiber are by the first hole, described non-resilient skin is provided with the second hole, and described electrode exposes described non-resilient skin by the second hole, described near-infrared probe and the arrangement straggly of described electrode.
2. near infrared spectroscopy according to claim 1 and electrode joint-detection device, it is characterized in that, described near-infrared probe comprises probe positioner, fibre holder, described probe positioner is fixed on described non-resilient skin by draw-in groove, described fibre holder is arranged in the middle of described probe positioner, has through hole and be used for grip optical fiber in the middle of described fibre holder.
3. near infrared spectroscopy according to claim 1 and electrode joint-detection device, is characterized in that, described first hole diameter is greater than described luminous source optical fiber or detection optical fiber diameter.
4. near infrared spectroscopy according to claim 1 and electrode joint-detection device, is characterized in that, described second hole diameter is greater than described electrode diameter.
5. near infrared spectroscopy according to claim 2 and electrode joint-detection device, is characterized in that, has the through hole larger than described fibre holder external diameter in the middle of described probe positioner.
6. near infrared spectroscopy according to claim 2 and electrode joint-detection device, it is characterized in that, described near-infrared probe also comprises elastic pressing cap, and described elastic pressing cap two ends are fixed on described probe positioner both sides, for being pressed in optical fiber elbow, elastic pressure is applied to optical fiber.
7. near infrared spectroscopy according to claim 1 and electrode joint-detection device, is characterized in that, electrode standard positioning system selects brain electricity 10-10,10-20,10-20 expanding system or other electrode standard positioning systems.
8. near infrared spectroscopy according to claim 1 and electrode joint-detection device, is characterized in that, described non-resilient skin and described elastic inner layer are linked together by elastomeric material.
9. near infrared spectroscopy according to claim 1 and electrode joint-detection device, is characterized in that, described non-resilient skin is by plastics, and non-resilient rubber, thermoplastic material or other non-elastic materials are made.
10. near infrared spectroscopy according to claim 1 and electrode joint-detection device, is characterized in that, described elastic inner layer is by elastic woven material, and gum elastic or other elastomeric materials are made.
11. near infrared spectroscopies according to claim 6 and electrode joint-detection device, is characterized in that, described probe positioner, and fibre holder and elastic pressing cap adopt rubber, and latex or other non-metallic elastic material manufacture.
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103445774A (en) * | 2013-07-14 | 2013-12-18 | 北京师范大学 | Photoelectric electrode capable of synchronously collecting EEG signals and blood oxygen signals |
| CN106037665A (en) * | 2016-07-06 | 2016-10-26 | 苏州格林泰克科技有限公司 | Near infrared spectrum cerebral function imaging device |
| CN106037667A (en) * | 2016-07-06 | 2016-10-26 | 苏州格林泰克科技有限公司 | Electroencephalograph (EEG) and near-infrared spectroscopy combined collecting device |
| CN106137135A (en) * | 2016-08-10 | 2016-11-23 | 中国医学科学院生物医学工程研究所 | It is applied to the headgear of the electrical combined collection brain signal of transcranial magnetic stimulation |
| CN106937868B (en) * | 2017-03-03 | 2020-02-04 | 燕山大学 | Electroencephalogram and near infrared spectrum combined acquisition device applied to rat |
| CN108042131B (en) * | 2017-12-26 | 2024-07-12 | 武汉智普天创科技有限公司 | Portable cap for collecting brain signals by combining brain electricity and near infrared spectrum |
| CN110618094B (en) * | 2019-08-12 | 2022-03-15 | 山西省平遥牛肉集团有限公司 | Multi-index composite synchronous detection table for fresh beef and use method |
| CN113951901B (en) * | 2021-11-19 | 2024-03-01 | 中国中医科学院西苑医院 | Automatic analysis system and method for data acquisition effectiveness of electroencephalogram |
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| CN102894972A (en) * | 2011-07-26 | 2013-01-30 | 财团法人交大思源基金会 | Physiological signal collecting unit and probe thereof |
| CN102894971A (en) * | 2011-07-29 | 2013-01-30 | 中国科学院沈阳自动化研究所 | Helmet for acquiring brain signal by combining electroencephalography with near-infrared spectroscopy |
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| US7974671B2 (en) * | 2003-09-19 | 2011-07-05 | Hitachi Medical Corporation | Living body information signal processing system combining living body optical measurement apparatus and brain wave measurement apparatus and probe device used for the same |
| US8527035B2 (en) * | 2008-04-28 | 2013-09-03 | The Trustees Of Dartmouth College | System, optode and cap for near-infrared diffuse-optical function neuroimaging |
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| CN1692874A (en) * | 2004-05-08 | 2005-11-09 | 香港中文大学 | Finger ring type physiological information monitoring device |
| CN102894972A (en) * | 2011-07-26 | 2013-01-30 | 财团法人交大思源基金会 | Physiological signal collecting unit and probe thereof |
| CN102894971A (en) * | 2011-07-29 | 2013-01-30 | 中国科学院沈阳自动化研究所 | Helmet for acquiring brain signal by combining electroencephalography with near-infrared spectroscopy |
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