CN103721066B - A kind of decoction for the treatment of tumor - Google Patents
A kind of decoction for the treatment of tumor Download PDFInfo
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Abstract
The invention provides a kind of decoction for the treatment of tumor.The decoction of described treatment tumor is formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 14-16 part, Radix Astragali 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 11-13 part, Herba Hedyotidis Diffusae 9-11 part, Herba Scutellariae Barbatae 21.5-22.5 part, Herba Taraxaci 12.5-13.5 part, Poria 9-11 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Carapax Trionycis 9-11 part, Radix Scrophulariae 9-11.5 part, Herba Artemisiae Scopariae 9-11 part, Radix Bupleuri 9-11 part, Cortex Lycii 21.5-22.5 part, Cortex Mori 9-11.5 part, Fructus Gardeniae 9-11.5 part, Radix Glycyrrhizae 5-6.5 part.Prescription of the present invention is for tumor Primary Asthenia-Secondary Sthenia Syndrome, and meticulous compatibility, prescription is rigorous, uses clinical middle common Chinese medicine material, cheap, convenient and practical, and experiment proves that it has no side effect, and clinical effectiveness is remarkable.
Description
Technical field
The present invention relates to therapeutic field of tumor, specifically a kind of decoction for the treatment of tumor.
Background technology
Radiotherapy and chemotherapy are the essential therapeutic arsenals of malignant tumor, but its toxicity is very large.The anti-tumor medicine thing of current Clinical practice all has toxic and side effects in various degree, and they kill and wound again the cell of normal structure while killing tumor cell, especially kills and wounds the vigorous blood of growth promoter in human body, lymphocyte etc.The mode classification of cancer therapy drug untoward reaction is a lot, and according to the impact of cancer therapy drug on body different system, untoward reaction mainly contains hematotoxicity, gastrointestinal toxicity, mucosa lesions, liver toxicity, nephrotoxicity etc.
On traditional medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs basis, for common multiple pulmonary carcinoma, gastric cancer, the treatment of colorectal cancer, on the basis of conventional therapy, the lack of appetite abdominal distention that during being conceived to tumor chemoradiotherapy, patient occurs, indigestion and loss of appetite, it is diseases related that sweating is weak etc., establish emphasis disease and plant diagnosis and treatment specification, sum up and refine the obvious proved recipe of several clinical curative effect and feature therapies, promote, to the raising of patients ' life quality, the control of symptom and the attenuation synergistic of chemotherapeutics achieve very big effect, by the summary after clinical practice, treatment peri-operation period, surround system, the quality of life of radiotherapy interval patient, the controlling extent of clinical symptoms plays critical effect to curative effect and prognosis.
The traditional Chinese medical science thinks that tumor is systemic disease, weakened body resistance blood stasis, and residual poison is not clearly its pathogenic characteristic, and the basic reason of neoplasm metastasis is healthy energy virtual loss, accumulates in evil poison.No matter perform the operation or chemotherapeutic treatment, though reach and effectively subtract tumor and to uncharm object, but fundamentally do not remove the imbalance of patient's internal organs, negative and positive, QI and blood function, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs and wholistic therapy to be particular about according to Chinese traditional treatment tumor, include radiotherapy, chemotherapy in dialectical medication category, form doctor trained in Western medicine and attack heresy, the general layout of traditional Chinese medical science righting, adopt the method for the combination of Chinese and Western medicine to carry out oncotherapy and often can obtain good effect, the auxiliary therapeutic action of Chinese medicine to tumor patient also more and more gets the nod.
At present, the medicine being used for the treatment of tumor is a lot, but there is the defect that side effect is large all in various degree, have a strong impact on treatment and the rehabilitation of patient, particularly for patient's lack of appetite abdominal distention, indigestion and loss of appetite, sweating is weak etc., and diseases related medicine compares shortcoming, current needs develop a kind of action temperature and, untoward reaction is little, can prolonged application, and easy to use, determined curative effect, the new drug for the treatment of tumor.
Summary of the invention
The invention provides a kind of decoction for the treatment of tumor, can be used for the treatment of pulmonary, liver, all kinds of tumor of digestive tract, its action temperature and, untoward reaction is little, can prolonged application, and easy to use, and curative effect is fast, not easily rebounds, uses, carries, keeping is all very convenient.
A kind of decoction for the treatment of tumor provided by the invention, is formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 14-16 part, Radix Astragali 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 11-13 part, Herba Hedyotidis Diffusae 9-11 part, Herba Scutellariae Barbatae 21.5-22.5 part, Herba Taraxaci 12.5-13.5 part, Poria 9-11 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Carapax Trionycis 9-11 part, Radix Scrophulariae 9-11.5 part, Herba Artemisiae Scopariae 9-11 part, Radix Bupleuri 9-11 part, Cortex Lycii 21.5-22.5 part, Cortex Mori 9-11.5 part, Fructus Gardeniae 9-11.5 part, Radix Glycyrrhizae 5-6.5 part.
The invention provides a kind of further formula of decoction for the treatment of tumor, it is characterized in that being formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 14.5-15.5 part, Radix Astragali 45-55 part, Pseudobulbus Cremastrae Seu Pleiones 11-13 part, Herba Hedyotidis Diffusae 9.5-10.5 part, Herba Scutellariae Barbatae 21.5-22.5 part, Herba Taraxaci 12.5-13.5 part, Poria 9-11 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Carapax Trionycis 9-11 part, Radix Scrophulariae 9-11.5 part, Herba Artemisiae Scopariae 9-11 part, Radix Bupleuri 9-11 part, Cortex Lycii 21.5-22.5 part, Cortex Mori 9-11.5 part, Fructus Gardeniae 9-11.5 part, Radix Glycyrrhizae 5-6.5 part.
The invention provides a kind of decoction preferably formula for the treatment of tumor, it is characterized in that being formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 15 parts, the Radix Astragali 50 parts, Pseudobulbus Cremastrae Seu Pleiones 12 parts, Herba Hedyotidis Diffusae 10 parts, Herba Scutellariae Barbatae 22 parts, Herba Taraxaci 13 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, Carapax Trionycis 10 parts, Radix Scrophulariae 10 parts, Herba Artemisiae Scopariae 10 parts, Radix Bupleuri 10 parts, Cortex Lycii 22 parts, Cortex Mori 10 parts, Fructus Gardeniae 10 parts, 6 parts, Radix Glycyrrhizae.
Radix Rhodiolae in decoction of the present invention, the Radix Astragali can righting gas, enhancing human body immunity functions, and having reached the merit of strengthening vital QI to eliminate pathogenic factors, is be monarch drug, i.e. principal agent; Wherein Radix Rhodiolae has magical effect of strengthening healthy qi, benefiting qi and nourishing blood, YIN nourishing lung benefiting, and benefiting QI for activating blood circulation, promotes blood circulation and relieving asthma, and can promote the nonspecific resistance of human body to destructive stimulus, strengthens the adaptability of human body, can be used for the effect such as promoting blood circulation and hemostasis, nourishing vigour; Radix Astragali nature and flavor are sweet, tepor, and main pharmacological is " benefiting QI for strengthening the superficies ", can " diuretic ", also can " promoting pus discharge and tissue regeneration strengthening ".
In decoction of the present invention, Pseudobulbus Cremastrae Seu Pleiones, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae and Herba Taraxaci can heat-clearing and toxic substances removing, anticancer tumors of dispelling, and are be ministerial drug; Wherein Pseudobulbus Cremastrae Seu Pleiones nature and flavor are bitter, micro-pungent, cool, and effectiveness: herb: dispersing swelling and dissipating binds, reduces phlegm, heat-clearing and toxic substances removing, controls carbuncle furuncle and phyma, laryngopharynx swelling and pain, sore throat ， Luo Scrofulaceum; Its patent medicine bitter in the mouth of Herba Hedyotidis Diffusae, light, cold in nature, primary efficacy is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness, outstanding kind treatment all kinds inflammation; Herba Scutellariae Barbatae acrid in the mouth, hardship, cold in nature, return lung meridian, Liver Channel, kidney channel, control haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice, have sore throat, lung abscess, furuncle, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom; Herba Taraxaci can heat-clearing and toxic substances removing, and diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
In decoction of the present invention, Carapax Trionycis, Radix Scrophulariae, Radix Bupleuri, Herba Artemisiae Scopariae, Poria and the Rhizoma Atractylodis Macrocephalae can hard masses softening and resolving, soothing livers and strengthening spleens, are be adjuvant drug; Cortex Lycii, Cortex Mori, Fructus Gardeniae and Radix Glycyrrhizae can clearind deficient heat coordinating the actions of various ingredients in a prescription, are for making medicine.
In use, potion, added decocting juice 200ml, took at twice prescription of the present invention every day, each serving using 100ml medicine juice, was a course for the treatment of with 10 days, general one the course for the treatment of symptom namely have clear improvement.
The present invention is using Radix Rhodiolae and the Radix Astragali as monarch drug, Pseudobulbus Cremastrae Seu Pleiones, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae and Herba Taraxaci are as ministerial drug, Carapax Trionycis, Radix Scrophulariae, Radix Bupleuri, Herba Artemisiae Scopariae, Poria and the Rhizoma Atractylodis Macrocephalae are as adjuvant drug, Cortex Lycii, Cortex Mori, Fructus Gardeniae and Radix Glycyrrhizae are as making medicine, full policy is to the disease of tumor deficiency in origin table reality, meticulous compatibility, prescription is rigorous, use this prescription decoction for treatment primary lung cancer, hepatocarcinoma, the loss of appetite that the tumors such as colon cancer cause, dysphagia, sweating is weak, the needle-likes such as cancerous protuberance pain have positive effect, greatly play righting to dispel effect of tumor, and the medicine in prescription of the present invention all uses clinical middle common Chinese medicine material, cheap, convenient and practical, and experiment proves that it has no side effect, clinical effectiveness is remarkable.
Detailed description of the invention
Embodiment 1:
The present embodiment provides a kind of decoction for the treatment of tumor, is formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight grams: Radix Rhodiolae 14g, Radix Astragali 40g, Pseudobulbus Cremastrae Seu Pleiones 11g, Herba Hedyotidis Diffusae 9g, Herba Scutellariae Barbatae 21.5g, Herba Taraxaci 12.5g, Poria 9g, Rhizoma Atractylodis Macrocephalae 9g, Carapax Trionycis 9g, Radix Scrophulariae 9g, Herba Artemisiae Scopariae 9g, Radix Bupleuri 9g, Cortex Lycii 21.5g, Cortex Mori 9g, Fructus Gardeniae 9g, Radix Glycyrrhizae 5g.
Embodiment 2:
The present embodiment provides a kind of decoction for the treatment of tumor, is formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 16g, Radix Astragali 60g, Pseudobulbus Cremastrae Seu Pleiones 13g, Herba Hedyotidis Diffusae 11g, Herba Scutellariae Barbatae 22.5g, Herba Taraxaci 13.5g, Poria 11g, Rhizoma Atractylodis Macrocephalae 11g, Carapax Trionycis 11g, Radix Scrophulariae 11g, Herba Artemisiae Scopariae 11g, Radix Bupleuri 11g, Cortex Lycii 22.5g, Cortex Mori 11.5g, Fructus Gardeniae 11.5g, Radix Glycyrrhizae 6.5g.
Embodiment 3:
The present embodiment provides a kind of decoction for the treatment of tumor, is formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 15g, Radix Astragali 50g, Pseudobulbus Cremastrae Seu Pleiones 12g, Herba Hedyotidis Diffusae 10g, Herba Scutellariae Barbatae 22g, Herba Taraxaci 13g, Poria 10g, Rhizoma Atractylodis Macrocephalae 10g, Carapax Trionycis 10g, Radix Scrophulariae 10g, Herba Artemisiae Scopariae 10g, Radix Bupleuri 10g, Cortex Lycii 22g, Cortex Mori 10g, Fructus Gardeniae 10g, Radix Glycyrrhizae 6g.
It is below the explanation of relevant performance of Drug toxicity trails for the present invention and clinical observation, result of use.
Drug toxicity trails
(1) test objective
Observe the toxic reaction produced after animal uses the present invention.
(2) test material
1, animal: select adult healthy SD rat 60, original body mass 80-100g, male and female half and half, female rats all without pregnant, is provided by Disease Prevention Control Center, Hubei Prov.
2, medicine: per weight dosage is by 10 times of calculating (clinical application amount foundation Pharmacopoeia of the People's Republic of China version in 2010) of clinical application amount.I side: the decoction-righting for the treatment of tumor for the present invention is dispelled tumor soup, wherein Radix Rhodiolae 1.5g, Radix Astragali 5.0g, Pseudobulbus Cremastrae Seu Pleiones 1.2g, Herba Hedyotidis Diffusae 1.0g, Herba Scutellariae Barbatae 2.2g, Herba Taraxaci 1.3g, Poria 1.0g, Rhizoma Atractylodis Macrocephalae 1.0g, Carapax Trionycis 1.0g, Radix Scrophulariae 1.0g, Herba Artemisiae Scopariae 1.0g, Radix Bupleuri 1.0g, Cortex Lycii 2.2g, Cortex Mori 1.0g, Fructus Gardeniae 1.0g, Radix Glycyrrhizae 0.6g.Unit: g/kg.
3, instrument: Au800 automatic clinical chemistry analyzer, Japanese OLYMPUS; AU-TOLAB blood cell automatic analyzer, Italian AMS; Untest2200 Urine Analyzer, Guilin City Medical Treatment Electronic Equipment Factory; Radiation plague enumerator.
(3) test method
1,60 SD rats are divided into two groups, often organize 20, male and female half and half, female rats is all without pregnant.Experimental animal male and female sub-cage rearing, 5, every cage, quantitative feeding (every cage 1000-1200g/ week), normal feedstuff is experimental mouse full-valence pellet feed, freely drinks water.Experimental temperature (22 ± 2) DEG C, humidity 60%-80%.The light and shade cycle of natural lighting and about 12h.
After SD rat is bought, under this laboratory rearing condition, adapt to 2 weeks, observe general behavior performance.Test pre-test animal ingestion amount.
2, divide into groups
Two groups of SD rats wherein one group give normal saline gavage, be matched group; Another group to be dispelled tumor side's decocting gavage with righting, is test group;
3, medication
The decoction prescription for the treatment of tumor of the present invention adds water 200ml by test group, respectively decocting 2 times, and get liquid 50ml, raise device gastric infusion with filling, every day 2 times, each volume is 0.2ml/10g body weight, successive administration 26 weeks.Matched group gives the normal saline of same volume.Experimental animal is weighed weekly 1 time, according to body weight change adjustment dosage.24h after administration in the 13rd week, often group puts to death 1/3(male and female half and half), observe and detect indices; Remaining continuation administration was observed to 26 weeks, and 24h after last 1 administration, often organizes and put to death 1/3(male and female half and half again) to observe and to detect indices; Remaining 1/3 carries out 8 week convalescent period observes.
4, test item and the time
The general status of animal is observed in 4.1 general inspections every day: as the mental status, reaction, behavioral activity, defecation situation, hair color, cleannes etc.Body weight change situation and food ration measure weekly 1 time.
After 4.2 hematological examination administrations, the 13rd, 26 week and drug withdrawal recover the end of term (the 34th week) and detect following index respectively: red blood cell count(RBC) (RBC), content of hemoglobin (HGB), packed cell volume (HCT); Numeration of leukocyte (WBC), platelet count (PLT), lymphocyte comparative counting (LY), neutrophilic granulocyte comparative counting (NE), mononuclear cell comparative counting (Mon) and clotting time (CT).
4.3 blood parameters to check after administrations the 13rd, 26 week and the drug withdrawal recovery end of term (the 34th week) detects following index respectively: Lomefloxacin aspartate injection (AST), alanine aminotransferase (ALT), alkali phosphatase (AST), gross protein (TP), albumin (ALB), total bilirubin (TB), blood glucose (GLU), blood urea nitrogen (BUN), creatinine (Crea), T-CHOL (TG, uric acid (UA), blood potassium (K+), blood sodium (Na+), blood calcium (Ca+) and B2M (serum β 2-MG, renal tubular function obstacle Sensitivity Index).
After 4.4 routine urine examination,urine for routine and urine biochemical analysis administration, the 13rd, 26 week and drug withdrawal recover the end of term (the 34th week) each survey 1 time.Animal metabolism cage list cage is raised and is collected 24h urine, overnight fasting before test, detects glucose (GLU), urine bilirubin (BIL), ketoboidies (KET), pH value, protein, urobilinogen (URO), nitrite (NIT), urine is occulted blood (BLO), proportion and leukocyte (WBC); Quantitative determination of radioimmunoassay urine β 2-MG(renal tubular function obstacle sensitive indicator).
4.5 system postmortems and histopathologic examination carry out macroscopy to each internal organs, the organs such as heart, liver, spleen, lungs, kidney, adrenal gland, thymus, thyroid, pancreas, brain, uterus, ovary, testis, prostate are taken out and weighs, calculate organ coefficient (organ weights/body weight).
With light microscopic, histological examination is carried out to above-mentioned internal organs and thymus, pancreas, spinal cord, hypophysis cerebri, optic nerve, lymph node, bladder, bone marrow (breastbone), Stomach duodenum, ileum, coton and rectal etc.
(4) result
1, ordinary circumstance is observed:
Two groups of rats are showed no obvious abnormalities.
2, on the impact of rat blood index
The results are shown in Table 1 and table 2.Administration is after 13 weeks and 26 weeks, test group (namely using I side's) examine index all without significant difference compared with matched group, after drug withdrawal recovers 8 weeks, each group examine indices compared with matched group all without significant difference.
Table 1 continuously ig administration 26 weeks and 8 week convalescent period on the impact of rat blood cytology index (n=10,
)
Table 2 continuously ig administration 26 weeks and 8 week convalescent period on the impact of rat blood cytology index (n=10,
)
3. on the impact of rat blood biochemical indicator
The results are shown in Table 3 and table 4.Administration is after 13 weeks and 26 weeks, index that Chinese drug-treated group is examined compared with matched group all without significant difference.After drug withdrawal recovers 8 weeks, each group examine indices compared with matched group all without significant difference.
Table 3 continuously ig administration 26 weeks and 8 week convalescent period on the impact of rat blood biochemical indexes (n=10,
)
Table 4 continuously ig administration 26 weeks and 8 week convalescent period on the impact of rat blood biochemical indexes (n=10,
)
4, on the impact of rat urine
The results are shown in Table 5 and table 6.Administration is after 13 weeks and 26 weeks, index that Chinese drug-treated group is examined compared with matched group all without significant difference.After drug withdrawal recovers 8 weeks, each group examine indices compared with matched group all without significant difference.
Table 5 continuously ig administration 26 weeks and 8 week convalescent period on the impact of rat urine biochemical indicator (n=10,
)
Table 6 continuously ig administration 26 weeks and 8 week convalescent period on the impact of rat urine biochemical indicator (n=10,
)
5. system postmortem and histopathologic examination
Each treated animal is all without macroscopic pathological change.Histological examination shows that each group of each internal organs are compared with matched group and is showed no obvious pathological change.
6. brief summary
Through test show adopt of the present invention a kind of treat the decoction decocting of tumor after continuous 26 weeks to SD rat gavage after, rat blood index, biochemical indicator, urine and pathology etc. are had no effect, there is not any toxic reaction, prove prescription avirulence of the present invention.
Clinic Case one: applicant is for adopting the decoction treatment cancerous protuberance for the treatment of tumor of the present invention, the summary of the routine clinical observation of cancerous pain 400, specific as follows:
In in May ,-2013 in August, 2012, the patient of the symptoms such as the loss of appetite that Affiliated Hospital of Hubei University of Chinese Medicine uses a kind of decoction prescription for the treatment of tumor described in the embodiment of the present invention one to cause tumors such as 400 routine primary lung cancers, hepatocarcinoma, colon cancer, dysphagia, sweating are weak, cancerous protuberance pain treats, and clinical observation has been carried out to it, it is as follows that existing situation of being observed by pertinent clinical sums up report:
One, physical data
The sweating that the tumors such as the court in above-mentioned period common diagnosis and treatment pulmonary carcinoma, gastric cancer, esophageal carcinoma cause is weak, lack of appetite abdominal distention patient amounts to 400 examples, is divided into treatment group and matched group at random.Treatment group 340 example, man 160 example, female 180 example; Age 50-65 year, 59 years old mean age, wherein less than 55 years old 275 examples (80.8%); The morbidity course of disease more than 3 months 266 examples, more than 6 months 74 examples; Diagnosing 113 example, gastric cancer 91, colon cancer 32 example, other 54 examples.Matched group 60 example, man 27 example, female 33 example; Age 55-64 year.58 years old mean age, wherein less than 53 years old 48 examples (80.0%); The morbidity course of disease: more than 3 months 49 examples, more than 6 months 11 examples; Diagnosing 25 example, esophageal carcinoma 21, hepatocarcinoma 6 example, other 8 examples.
Two, Therapeutic Method
Matched group gives the nutritional support such as fatsoluble vitamin, water soluble vitamins, once a day, and SHENQI FUZHENG ZHUSHEYE, once a day; Treatment group, with decoction decocting oral medication treatment of control group method basis giving the treatment tumor described in the embodiment of the present invention one, every day 1 dose, decocts juice 200ml, divide 2 clothes, each serving the medicine juice with 100ml, two groups was all a course for the treatment of with 10 days, treated a course for the treatment of.
Three, evaluation criteria
Effective: subjective symptoms (loss of appetite, sweating, weak, lack of appetite abdominal distention etc.) disappears; Effective: subjective symptoms is improved; Invalid: treat after 10 days, symptom, sign are all not improved.
Four, result
1. liang group comparitive study: effective 307 examples in treatment group 340 example, effective 30 examples, invalid 3 examples, cure rate 90.4%, total effective rate 99.0%; 40 examples are cured, effective 13 examples, invalid 7 examples, cure rate 66.7%, total effective rate 88.3% in matched group 60 example.Two groups of curative effect comparitive study are as following table:
| Group | Number of cases | Effective | Effectively | Invalid | Cure rate | Total effective rate |
| Treatment group | 340 | 307 | 30 | 3 | 90.4% | 99.0% |
| Matched group | 60 | 40 | 13 | 7 | 66.7% | 88.3% |
From table, display, can find out the treatment curative effect for the treatment of group apparently higher than matched group;
2. treatment time compares: the average effective time for the treatment of group 5 days, and the average effective time of matched group is 9 days, and two groups for the treatment of times compare significant difference, and wherein the treatment time for the treatment of group shortens greatly;
3. follow-up observation: all cases follow up a case by regular visits to 2-3 days, none routine subjective symptoms for the treatment of group occurs, the routine symptom of matched group 16 occurs, two groups are compared and have significant difference, and the self-healing performance of its treatment group is high.
Five, conclusion
To in the understanding of tumor etiology, inherit tradition point endogenous cause of ill, exopathogenic factor, understanding chemical principle because of causes of disease such as, Viral cause and heredity again, and recognizing that town heresy relation is the key factor in cancerous protuberance is fallen ill.The importance of " healthy energy " is proposed in the good and evil relation of tumor.Ancients' cloud: " pathogen gathered, and its gas must be empty." morbidity of cancerous protuberance, being the interactional results of good and evil, is also collective defense function and the interactional result of cancerigenic factor.Evil victory just declines, and cancerous protuberance is then fallen ill, and healthy energy is vigorous, though then there is its cancerous protuberance evil also not necessarily to fall ill.The medical needle of TCM on tumor, to this feature of deficiency in origin and excess in superficiality, treatment gives Radix Rhodiolae, Radix Astragali righting gas, enhancing human body immunity function, has reached the merit of strengthening vital QI to eliminate pathogenic factors; Pseudobulbus Cremastrae Seu Pleiones, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herba Taraxaci heat-clearing and toxic substances removing, anticancer Eradicates tumor; Carapax Trionycis, Radix Scrophulariae, Radix Bupleuri, Herba Artemisiae Scopariae, Poria, Rhizoma Atractylodis Macrocephalae hard masses softening and resolving, soothing liver and strengthening spleen; Cortex Lycii, Cortex Mori, Fructus Gardeniae, Radix Glycyrrhizae clearind deficient heat coordinating the actions of various ingredients in a prescription, full side plays righting altogether and to dispel effect of tumor.
Clinic Case two: applicant for the decoction for the treatment of tumor of the present invention for the clinical observation for the treatment of pulmonary carcinoma deficiency of both QI and YIN disease
Pulmonary carcinoma type of deficiency of both QI and YIN shows as dry cough, it is micro-to cough low voice, or sputum mixed with blood, diseases such as all having spiritlessness and weakness, xerostomia, breathe hard, be indigestion and loss of appetite.2011-2012 years, use decoction treatment pulmonary carcinoma type of deficiency of both QI and YIN patient totally 80 examples for the treatment of tumor of the present invention, and carried out clinical observation, existing report of observed result being summed up was as follows:
One, physical data
80 examples are divided into treatment group and matched group by 2011-2012 years diagnosis and treatment pulmonary carcinoma type of deficiency of both QI and YIN patients totally 80 examples at random.Treatment group 60 example, wherein nonsmall-cell lung cancer 42 example, scale cancer 12 example, adenocarcinoma 6 example; Man 47 example, female 13 example; 52 years old mean age.Matched group 20 example, wherein nonsmall-cell lung cancer 14 example, scale cancer 4 example, adenocarcinoma 2 example; Man 13 example, female 7 example; 51 years old mean age.
Two, Therapeutic Method
It is oral that matched group gives decoction made from radix adenophorea, tuber of dwarf lilyturf (Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, the Radix Rehmanniae, Radix Scrophulariae, Bulbus Fritillariae Uninbracteatae, Cortex Moutan, Semen Lepidii (Semen Descurainiae), the Radix Paeoniae Alba), every day potion, decocting 200ml, point secondary clothes; The righting that treatment group gives the treatment tumor described in the embodiment of the present invention two tumor side's soup (Radix Rhodiolae, the Radix Astragali, Pseudobulbus Cremastrae Seu Pleiones, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Carapax Trionycis, Radix Scrophulariae, Herba Artemisiae Scopariae, Radix Bupleuri, Cortex Lycii, Cortex Mori, Fructus Gardeniae, Radix Glycyrrhizae) of dispelling is oral.Every day 1 dose, decocting 200ml, point 2 clothes.Be a course for the treatment of with 10 days, take three courses for the treatment of.
Three, evaluation criteria
Effective: patient's spiritlessness and weakness, xerostomia, breathe hard, indigestion and loss of appetite disappearance;
Effective: patient's spiritlessness and weakness, xerostomia, alleviation of breathing hard, appetite takes a turn for the better;
Invalid: patients symptomatic is without improvement.
Four, result
Effective 13 examples in treatment group 60 example, effective 36 examples, invalid 11 examples, total effective rate 81.6%; Effective 3 examples in matched group 20 example, effective 9 examples, invalid 8, total effective rate 60.0%.2 groups of comparitive study have significant difference.
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 60 | 13 | 36 | 11 | 81.6% |
| Matched group | 20 | 3 | 9 | 8 | 60.0% |
Five, discuss
Lung cancer morbidity rate is in rising trend, is the malignant tumor of serious harm health.At present at operation, positive chemicotherapy, the aspects such as Biotherapeutics are being explored, but effect is still undesirable.And the traditional Chinese medical science has unique effect improving the fermentation such as patients symptomatic, band tumor existence, be therefore one of clinical at present important topic to the research of Chinese medicine.The righting for the treatment of tumor of the present invention is dispelled tumor side's strengthening vital QI to eliminate pathogenic factors, and immunostimulant, has unique curative effect for primary disease, be worth applying in clinical treatment.
Clinic Case three: applicant dispels for the righting for the treatment of tumor of the present invention the experience brief summary of tumor side's treatment colon cancer 12 example.
In March ,-2012 in June, 2011, our unit uses righting to dispel tumor side's treatment colorectal cancer patients 12 example, achieves good therapeutic effect, existing that therapeutic process is as follows with summary of experience:
One, physical data
The patient of non-row chemotherapy after whole 12 examples are Operation of Colon Carcinoma, patient is dizzy, pale complexion, fatigue and weakness, abdominal distention, cold type of pain.In age 60-72 year, male 4 people, women 8 people, all gives nutritional support treatment.
Two, therapeutic scheme
On nutrition treatment basis, to treatment tumor of the present invention to give the righting tumor side (Radix Rhodiolae, the Radix Astragali, Pseudobulbus Cremastrae Seu Pleiones, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Carapax Trionycis, Radix Scrophulariae, Herba Artemisiae Scopariae, Radix Bupleuri, Cortex Lycii, Cortex Mori, Fructus Gardeniae, Radix Glycyrrhizae) that dispels oral.Every day 1 dose, decocting 200ml, point 2 clothes.Be a course for the treatment of with 10 days, take three to four courses for the treatment of.
Three, result
In 12 people, after having 3 people to take a course for the treatment of, lack of appetite abdominal distention, cold type of pain symptom take a turn for the better, and take transference cure after 3 courses for the treatment of, after 6 people take four courses for the treatment of, symptom alleviates, and 3 people are not improved.
Four, discuss
Colon cancer is one of a kind of modal malignant tumor, the traditional Chinese medical science adopt righting dispel tumor side intervene obviously can improve the symptoms such as patient is weak, dizzy, indigestion and loss of appetite, diarrhoea, stomachache, xerostomia, improve life in patients, have positive effect at clinical expansion.
Five, model case
Liu's ××, female, 66 years old, patient because stool band blood January is to Wuhan City No.1 Hospital's row colonoscopy in June, 2010, is thought of as colon cancer, arrived Concord Hospital's row Operation of Colon Carcinoma June 20, postoperative disease inspection well-differentiated adenocarcinoma. periodic review thereafter, has no obvious transfer and relapse.Patient mental is general, poor appetite, weak, occasionally has constipation with dry stool, urine can, pale tongue tongue is white, deep,thready and forceless pulse.The righting giving the treatment tumor described in the embodiment of the present invention three tumor side (Radix Rhodiolae, the Radix Astragali, Pseudobulbus Cremastrae Seu Pleiones, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herba Taraxaci, Poria, the Rhizoma Atractylodis Macrocephalae, Carapax Trionycis, Radix Scrophulariae, Herba Artemisiae Scopariae, Radix Bupleuri, Cortex Lycii, Cortex Mori, Fructus Gardeniae, Radix Glycyrrhizae) that dispels is oral.Every day 1 dose, decocting 200ml, point 2 clothes.Once a day, appetite is good, does not tell giddy to take patient stool after 30 days, without weak tired sleeping.
Prescription of the present invention is for the disease of tumor deficiency in origin table reality, and meticulous compatibility, prescription is rigorous, uses clinical middle common Chinese medicine material, cheap, convenient and practical, and experiment proves that it has no side effect, and clinical effectiveness is remarkable.Chinese medicine then untoward reaction is little, can prolonged application.Found by this research, the symptoms such as the lack of appetite abdominal distention that the decoction for the treatment of tumor of the present invention causes treatment tumor, indigestion and loss of appetite weak, sweating have obvious effect, substantially improve the symptom of patient, improve curative effect, improve quality of life of patients, patient can be helped to be with the advantages such as tumor existence, and clinic is applied.
Claims (3)
1. treat a decoction for tumor, it is characterized in that being formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 14-16 part, Radix Astragali 40-60 part, Pseudobulbus Cremastrae Seu Pleiones 11-13 part, Herba Hedyotidis Diffusae 9-11 part, Herba Scutellariae Barbatae 21.5-22.5 part, Herba Taraxaci 12.5-13.5 part, Poria 9-11 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Carapax Trionycis 9-11 part, Radix Scrophulariae 9-11.5 part, Herba Artemisiae Scopariae 9-11 part, Radix Bupleuri 9-11 part, Cortex Lycii 21.5-22.5 part, Cortex Mori 9-11.5 part, Fructus Gardeniae 9-11.5 part, Radix Glycyrrhizae 5-6.5 part.
2. the decoction for the treatment of tumor according to claim 1, is characterized in that being formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 14.5-15.5 part, Radix Astragali 45-55 part, Pseudobulbus Cremastrae Seu Pleiones 11-13 part, Herba Hedyotidis Diffusae 9.5-10.5 part, Herba Scutellariae Barbatae 21.5-22.5 part, Herba Taraxaci 12.5-13.5 part, Poria 9-11 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Carapax Trionycis 9-11 part, Radix Scrophulariae 9-11.5 part, Herba Artemisiae Scopariae 9-11 part, Radix Bupleuri 9-11 part, Cortex Lycii 21.5-22.5 part, Cortex Mori 9-11.5 part, Fructus Gardeniae 9-11.5 part, Radix Glycyrrhizae 5-6.5 part.
3. the decoction for the treatment of tumor according to claim 1, is characterized in that being formed by the raw material of Chinese medicine Pharmaceutical formulations of following weight parts: Radix Rhodiolae 15 parts, the Radix Astragali 50 parts, Pseudobulbus Cremastrae Seu Pleiones 12 parts, Herba Hedyotidis Diffusae 10 parts, Herba Scutellariae Barbatae 22 parts, Herba Taraxaci 13 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, Carapax Trionycis 10 parts, Radix Scrophulariae 10 parts, Herba Artemisiae Scopariae 10 parts, Radix Bupleuri 10 parts, Cortex Lycii 22 parts, Cortex Mori 10 parts, Fructus Gardeniae 10 parts, 6 parts, Radix Glycyrrhizae.
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