CN103705666B - A kind of oral drugs treating stone in urinary system and preparation method - Google Patents
A kind of oral drugs treating stone in urinary system and preparation method Download PDFInfo
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- CN103705666B CN103705666B CN201310641467.XA CN201310641467A CN103705666B CN 103705666 B CN103705666 B CN 103705666B CN 201310641467 A CN201310641467 A CN 201310641467A CN 103705666 B CN103705666 B CN 103705666B
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- 239000004575 stone Substances 0.000 title claims abstract description 30
- 230000002485 urinary effect Effects 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 229940126701 oral medication Drugs 0.000 title description 3
- 239000003814 drug Substances 0.000 claims abstract description 32
- 241000522190 Desmodium Species 0.000 claims abstract description 13
- 241000405414 Rehmannia Species 0.000 claims abstract description 13
- 241000522254 Cassia Species 0.000 claims abstract description 11
- 238000010410 dusting Methods 0.000 claims abstract description 10
- 240000006995 Abutilon theophrasti Species 0.000 claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 239000006187 pill Substances 0.000 claims abstract description 8
- 239000002775 capsule Substances 0.000 claims abstract description 5
- 239000002245 particle Substances 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims abstract description 3
- 229940079593 drug Drugs 0.000 claims description 5
- 239000011812 mixed powder Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 claims description 4
- 235000019082 Osmanthus Nutrition 0.000 claims description 2
- 241000333181 Osmanthus Species 0.000 claims description 2
- 235000013372 meat Nutrition 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 230000001225 therapeutic effect Effects 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 2
- 238000004140 cleaning Methods 0.000 abstract 1
- 241000411851 herbal medicine Species 0.000 abstract 1
- 230000007059 acute toxicity Effects 0.000 description 3
- 231100000403 acute toxicity Toxicity 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 231100000456 subacute toxicity Toxicity 0.000 description 3
- 230000006378 damage Effects 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 208000037157 Azotemia Diseases 0.000 description 1
- 206010007026 Calculus urethral Diseases 0.000 description 1
- 206010020524 Hydronephrosis Diseases 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 206010038481 Renal necrosis Diseases 0.000 description 1
- 208000000014 Ureteral Calculi Diseases 0.000 description 1
- 208000004608 Ureteral Obstruction Diseases 0.000 description 1
- 208000006568 Urinary Bladder Calculi Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940121657 clinical drug Drugs 0.000 description 1
- 238000011461 current therapy Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
- 210000000626 ureter Anatomy 0.000 description 1
- 201000009160 urethral calculus Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
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Abstract
The invention discloses a kind of medicine treating stone in urinary system and preparation method, relate to technical field of traditional Chinese medicines.The medicine of the treatment stone in urinary system aim to provide that a kind of availability is high, row's stone success rate is high, row's stone time is short, antiinflammatory action strong, have no side effect, having wide range of applications and preparation method.The party's medicine is with prepared rhizome of rehmannia, black suitable sheet, RHIZOMA ALISMATIS from Sichuan of China, desmodium, chingma abutilon seed, six kinds of Chinese herbal medicines of upper Chinese cassia tree as raw material, by selecting materials, cleaning, is dried；Weigh, grind, cross dusting cover, be sufficiently mixed, be finally processed into what the several step of pill, particle, capsule or drink completed.In terms of clinical therapeutic efficacy, medicine of the present invention is to various stone in urinary system and all kinds calculus, all have a good result for the treatment of and safe and free of toxic and side effects.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, specifically, the present invention relates to a kind of stone in urinary system for the treatment of
Medicine and preparation method.
Background technology
Uropoiesis bar calculus is a kind of common disease, frequently-occurring disease, with pain in the back, side or bilateral underbelly severe pain, urgent urination,
Odynuria, frequent micturition, blood urine and n and V general malaise are cardinal symptom, and the incidence of disease is high, and man, female the old and the young are all
Send out, especially in summer, autumn.Calculus causes ureter upper, middle and lower end ureteral obstruction to cause to urinate
Difficulty, hydronephrosis, cause to patient's physical and mental health and big injury and misery, even cause renal insufficiency,
The comprehensive complication such as uremia and renal necrosis.Doctor trained in Western medicine aspect often by ESWL or operation,
Costly, the hospital stays long, be also easy to injure surrounding tissue simultaneously, other organs around year cause damage,
Patient is difficult to accept.The molten stone of oral drugs, row's stone are the preferable selections for the treatment of stone in urinary system, but, mesh
The Chinese medicine price of front treatment urinary system is the highest, availability is the highest, row's stone success rate is relatively low, row's stone
Time is longer, antiinflammatory action is poor, have certain toxic and side effect, range of application the most extensive.
Summary of the invention
The technical problem to be solved in the present invention is to provide that a kind of price is relatively low, availability is high, row's stone success rate is high,
The medicine treating stone in urinary system that row's stone time is short, antiinflammatory action strong, has no side effect, have wide range of applications
Thing and preparation method.
The present invention solves that above-mentioned technical problem the technical scheme is that
The medicament that this medicine is made up of the raw material of following weight proportioning:
Prepared rhizome of rehmannia 15-35 part, black suitable sheet 12-22 part, RHIZOMA ALISMATIS from Sichuan of China 7-17 part, desmodium 50-70 part, winter
Certain herbaceous plants with big flowers 10-25 part, upper Chinese cassia tree 6-26 part.
The weight proportion scope preparing medicine of the present invention is:
Prepared rhizome of rehmannia 15-30 part, black suitable sheet 12-17 part, RHIZOMA ALISMATIS from Sichuan of China 7-12 part, desmodium 50-65 part, winter
Certain herbaceous plants with big flowers 10-20 part, upper Chinese cassia tree 6-21 part.
The weight proportion of medicine of the present invention is:
Prepared rhizome of rehmannia 15g, black suitable sheet 12g, RHIZOMA ALISMATIS from Sichuan of China 7g, desmodium 50g, chingma abutilon seed 10g, upper meat
Osmanthus 6g.
By the preparation method that above-mentioned each component makes medicine of the present invention it is:
(1) select materials according to formula；
(2) clean；
(3) it is dried；
(4) each drug component is weighed in the ratio of formula；
(5) each component weighed up is ground respectively；
(6) mixed powder is crossed dusting cover；
(7) medicinal powder after sieving is sufficiently mixed, and is processed into pill, particle, capsule or drink.
Wherein, being dried will airing in the sun；Or select dryer to dry, it is ensured that temperature≤60 DEG C.
Described dusting cover 300-350 to be selected mesh dusting cover.
Function: treat the transverse diameter kidney stone less than 10 millimeters, ureteral calculi, vesical calculus, urethral calculus
Companion's hydrops；Can accelerate after surgical calculus removing after ESWL to arrange stone, reduce because of rubble and postoperative residual
Stay calculus.
Usage and consumption: oral.Three times a day, each 10g of pill, particle, capsule, each 100ml of drink.
The invention has the beneficial effects as follows:
1, availability is high: collapse time is short, absorbs rapidly, and timely content is high, and drug availability is high.
2, row's stone success rate is high: clinical patients lithagogue rate reaches 87.8%, and not curing for many years can after patient takes
Calculus is discharged.
3, row's stone time is short: some patients improved symptom at 12 hours after taking, and within 53 hours, can get rid of knot
Stone, eliminates calculus painful.
4, antiinflammatory action is strong: to calculus, patient quickly diminishes inflammation, and does not stay future trouble.
5, have no side effect: take kidney harmless, safe and reliable.
6, applied range: for various stone in urinary system and all kinds calculus, all have good treatment to imitate
Really.
7, price is significantly less than like product.
Detailed description of the invention
Embodiment 1:
Be first according to formula and choose raw material: prepared rhizome of rehmannia, black along sheet, RHIZOMA ALISMATIS from Sichuan of China, desmodium, chingma abutilon seed, on
Chinese cassia tree；It is carried out；It is dried under the conditions of airing or selection dryer 50 DEG C in the sun；According to proportioning
Dosage choose raw material prepared rhizome of rehmannia 15g, black along sheet 12g, RHIZOMA ALISMATIS from Sichuan of China 7g, desmodium 50g, chingma abutilon seed 10g,
Upper Chinese cassia tree 6g；The most each component is ground respectively；Mixed powder is crossed 300 mesh dusting covers；To sieve
After medicinal powder be sufficiently mixed, be processed into pill.Every bottle of 100g.
Embodiment 2:
Be first according to formula and choose raw material: prepared rhizome of rehmannia, black along sheet, RHIZOMA ALISMATIS from Sichuan of China, desmodium, chingma abutilon seed, on
Chinese cassia tree；It is carried out；It is dried under the conditions of airing or selection dryer 55 DEG C in the sun；According to proportioning
Dosage choose raw material prepared rhizome of rehmannia 35g, black along sheet 22g, RHIZOMA ALISMATIS from Sichuan of China 7g, desmodium 70g, chingma abutilon seed 25g,
Upper Chinese cassia tree 26g；The most each component is ground respectively；Mixed powder is crossed 330 mesh dusting covers；To sieve
After medicinal powder be sufficiently mixed, be processed into pill.Every bottle of 100g.
Embodiment 3:
Be first according to formula and choose raw material: prepared rhizome of rehmannia, black along sheet, RHIZOMA ALISMATIS from Sichuan of China, desmodium, chingma abutilon seed, on
Chinese cassia tree；It is carried out；It is dried under the conditions of airing or selection dryer 60 DEG C in the sun；According to proportioning
Dosage choose raw material prepared rhizome of rehmannia 25g, black along sheet 17g, RHIZOMA ALISMATIS from Sichuan of China 13g, desmodium 60g, chingma abutilon seed 18g,
Upper Chinese cassia tree 16g；The most each component is ground respectively；Mixed powder is crossed 350 mesh dusting covers；To sieve
After medicinal powder be sufficiently mixed, be processed into pill.Every bottle of 100g.
The clinical implementation data of the medicine of the present invention:
The present invention and current therapies clinical drug comparitive study data:
As seen from the above table, invention group clinical efficacy is apparently higher than control group, and treatment time is short, good effect.
Drug safety evaluation result of the present invention
| Project | Standard-required | Measured result |
| Acute toxicity | Without acute toxicity | Without acute toxicity |
| Subacute toxicity | Without subacute toxicity | Without subacute toxicity |
| Sensitivity response | Without sensitivity response | Without sensitivity response |
| Aseptic bolt is looked into | Aseptic | Aseptic |
Conclusion: in terms of clinical therapeutic efficacy, medicine of the present invention to various stone in urinary system and all kinds calculus,
All there is good result for the treatment of, and safe and free of toxic and side effects.
It should be appreciated that the above-mentioned detailed description of the invention of the present invention is used only for exemplary illustration or explains this
The principle of invention, and be not construed as limiting the present invention.Therefore, without departing from the spirit and scope of the present invention
In the case of any modification, equivalent substitution and improvement etc. done, should be included in protection scope of the present invention it
In.Additionally, claims of the present invention be intended to fall into scope and border or
Whole in the equivalents on this scope and border change and modifications example.
Claims (8)
1. the medicine treating stone in urinary system, it is characterised in that: this medicine is by following weight proportioning
The medicament that raw material is made:
Prepared rhizome of rehmannia 15-35 part, black suitable sheet 12-22 part, RHIZOMA ALISMATIS from Sichuan of China 7-17 part, desmodium 50-70 part, winter
Certain herbaceous plants with big flowers 10-25 part, upper Chinese cassia tree 6-26 part.
The medicine for the treatment of stone in urinary system the most according to claim 1, it is characterised in that: described medicine
Weight proportion be:
Prepared rhizome of rehmannia 15-30 part, black suitable sheet 12-17 part, RHIZOMA ALISMATIS from Sichuan of China 7-12 part, desmodium 50-65 part, winter
Certain herbaceous plants with big flowers 10-20 part, upper Chinese cassia tree 6-21 part.
The medicine for the treatment of stone in urinary system the most according to claim 1, it is characterised in that: described medicine
Weight proportion be:
Prepared rhizome of rehmannia 15g, black suitable sheet 12g, RHIZOMA ALISMATIS from Sichuan of China 7g, desmodium 50g, chingma abutilon seed 10g, upper meat
Osmanthus 6g.
The medicine for the treatment of stone in urinary system the most according to claim 1, it is characterised in that: described medicine
Thing is pill, particle, capsule or drink.
5. according to the preparation method of the medicine treating stone in urinary system described in any of the above-described claim, its
It is characterised by: this preparation method comprises the steps:
(1) select materials according to formula；
(2) clean；
(3) it is dried；
(4) each drug component is weighed in the ratio of formula；
(5) each component weighed up is ground respectively；
(6) mixed powder is crossed dusting cover；
(7) medicinal powder after sieving is sufficiently mixed, and is processed into pill, particle, capsule or drink.
The preparation method of the medicine for the treatment of stone in urinary system the most according to claim 5, it is characterised in that:
Described being dried will airing in the sun；Or select dryer to dry.
The preparation method of the medicine for the treatment of stone in urinary system the most according to claim 6, it is characterised in that:
Dryer is selected to carry out drying temperature≤60 DEG C.
The preparation method of the medicine for the treatment of stone in urinary system the most according to claim 5, it is characterised in that:
Described dusting cover is 300-350 mesh dusting cover.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310641467.XA CN103705666B (en) | 2013-12-03 | 2013-12-03 | A kind of oral drugs treating stone in urinary system and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310641467.XA CN103705666B (en) | 2013-12-03 | 2013-12-03 | A kind of oral drugs treating stone in urinary system and preparation method |
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| Publication Number | Publication Date |
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| CN103705666A CN103705666A (en) | 2014-04-09 |
| CN103705666B true CN103705666B (en) | 2016-09-07 |
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| CN107496597A (en) * | 2017-09-26 | 2017-12-22 | 刘新民 | A kind of prescription for treating kidney stone and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101637559A (en) * | 2009-09-01 | 2010-02-03 | 吴敬龙 | Instant oral liquid for kidney stone |
| CN102657826A (en) * | 2012-06-03 | 2012-09-12 | 王光华 | Medicine used for treating renal calculus and preparation method thereof |
| CN102872437A (en) * | 2012-09-27 | 2013-01-16 | 强红兵 | Special-disease calculus-removing decoction for treating renal calculus |
| CN103110765A (en) * | 2013-02-18 | 2013-05-22 | 于浩 | Traditional Chinese medicine for treating renal calculi |
-
2013
- 2013-12-03 CN CN201310641467.XA patent/CN103705666B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101637559A (en) * | 2009-09-01 | 2010-02-03 | 吴敬龙 | Instant oral liquid for kidney stone |
| CN102657826A (en) * | 2012-06-03 | 2012-09-12 | 王光华 | Medicine used for treating renal calculus and preparation method thereof |
| CN102872437A (en) * | 2012-09-27 | 2013-01-16 | 强红兵 | Special-disease calculus-removing decoction for treating renal calculus |
| CN103110765A (en) * | 2013-02-18 | 2013-05-22 | 于浩 | Traditional Chinese medicine for treating renal calculi |
Non-Patent Citations (2)
| Title |
|---|
| 尿石症辨证用药经验谈;赵现朝;《浙江中医杂志》;20000516(第05期);第213页右栏第3段 * |
| 泌尿系结石30例治疗小结;张秀莲;《河北中医》;19861231(第02期);20-21 * |
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| CN103705666A (en) | 2014-04-09 |
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Granted publication date: 20160907 |