CN103705634A

CN103705634A - Ninxin capsule

Info

Publication number: CN103705634A
Application number: CN201410002681.5A
Authority: CN
Inventors: 闫明昌
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-01-04
Filing date: 2014-01-04
Publication date: 2014-04-09

Abstract

The invention provides a Ninxin capsule, and relates to a Chinese herbal medicine capsule preparation. The Ninxin capsule is an oral Chinese herbal medicine preparation which is used for treating arrhythmia. The Ninxin capsule is suitable for treating accidental and frequent ventricular premature beat comprising bigeminy arrhythmia and trigeminy arrhythmia. The Ninxin capsule is prepared from the following components: 30g of ginseng, 30g of codonopsis pilosula, 30g of radix scrophulariae, 30g of salvia miltiorrhiza, 30g of radix sophorae flavescentis and 10 Chinese dates. A preparation method comprises the following steps: finely selecting 30g of ginseng, 30g of codonopsis pilosula, 30g of radix scrophulariae, 30g of salvia miltiorrhiza, 30g of radix sophorae flavescentis and 10 Chinese dates; removing impurities; removing the kernels of the Chinese dates; performing artificial drying; smashing the dried six Chinese herbal medicines to form fine powder of 80 meshes; evenly stirring the fine powder and filling into the capsule. The Ninxin capsule has the functions and the treatment rules of nourishing yi and blood as well as benefiting qi and restoring pulse, and is mainly used for treating arrhythmia and especially the accidental and frequent ventricular premature beat comprising the bigeminy arrhythmia and the trigeminy arrhythmia.

Description

Mind calming capsule

Technical field

The present invention relates to a kind of Chinese medicinal capsule preparation, is a kind of ARR oral Chinese herbal and crude drugs preparations for the treatment of, and is applicable to accidental, frequent premature ventricular beats, comprises premature ventricular beat, the ARR treatment of premature ventricular beat.

Background technology

At present, although it is a lot of to treat ARR medicine, major part is Western medicine, for example beta-blockers, mexiletine, moracizine, Propafenone, amiodarone, and its therapeutic effect is all undesirable, side effect is larger, damage other organs official, for example amiodarone adverse reaction rate approximately 80%, visible abnormal thyroid function, also liver function injury be may there is, transaminase and alkali phosphatase rising, hepatitis and liver cirrhosis shown as; Some medications only have the effect of relief of symptoms in short-term, cure the symptoms, not the disease.

Summary of the invention

The object of the invention is to overcome the deficiencies in the prior art, a kind of good effect is provided, has no side effect, treating both the principal and secondary aspects of a disease a kind of treats ARR mind calming capsule.

The present invention adopts following technical scheme: mind calming capsule, its composition is: 30 grams of Radix Ginsengs, 30 grams of Radix Codonopsis, 30 grams of Radix Scrophulariae, 30 grams of Radix Salviae Miltiorrhizaes, 30 grams of Radix Sophorae Flavescentiss, 10 pieces, Fructus Jujubae, its manufacture method is: by 30 grams of Radix Ginsengs, 30 grams of Radix Codonopsis, 30 grams of Radix Scrophulariae, 30 grams of Radix Salviae Miltiorrhizaes, 30 grams of Radix Sophorae Flavescentiss, 10 pieces of selected impurity that remove of Fructus Jujubae, Removing Kernel for Date, artificial drying, dried Six-element Chinese medicine powder is broken into 80 order fine powders and mixes thoroughly, incapsulate.

Described capsule model is No. 0, and every capsules is 0.5 gram containing medicated powder amount.

Can be by said medicine part by weight proportioning, batch production.

Function of the present invention and the rule for the treatment of: yin nourishing is nourished blood, Yiqi and vein recovery, is mainly used in treating arrhythmia, and especially accidental, frequent premature ventricular beats comprise premature ventricular beat, premature ventricular beat.

Usage of the present invention and consumption: oral: each 2.0g, every day three times; 14 days courses for the treatment of.

The present invention is through 500 routine clinical trial certificates, and its cure rate is more than 90%.

The specific embodiment

Mind calming capsule, its composition is: 30 grams of Radix Ginsengs, 30 grams of Radix Codonopsis, 30 grams of Radix Scrophulariae, 30 grams of Radix Salviae Miltiorrhizaes, 30 grams of Radix Sophorae Flavescentiss, 10 pieces, Fructus Jujubae, its manufacture method is: by 30 grams of Radix Ginsengs, 30 grams of Radix Codonopsis, 30 grams of Radix Scrophulariae, 30 grams of Radix Salviae Miltiorrhizaes, 30 grams of Radix Sophorae Flavescentiss, 10 pieces of selected impurity that remove of Fructus Jujubae, Removing Kernel for Date, artificial drying, dried Six-element Chinese medicine powder is broken into 100 order fine powders and mixes thoroughly, incapsulate.

Usage of the present invention and consumption: oral: each 2.0g, every day three times, 14 days courses for the treatment of.

The present invention is through 500 routine clinical trial certificates, and its cure rate is more than 90%, without any side effects, and therapeutic effect is as follows:

Treatment time	Number of cases	Recovery from illness	Effectively	Invalid	Effective percentage	Cure rate
							20-50 days	500	478	22	0	100%	95.6%

Treatment standard is as follows.

Ventricular premature contraction efficacy assessment standard: recovery from illness, ventricular premature contraction number of times is treated front minimizing more than 90%; Effectively, ventricular premature contraction number of times is treated front minimizing more than 50%; Invalid, ventricular premature contraction number of times is treated front minimizing and is less than 50%, unchanged or increase the weight of.

ECG curative effect evaluation criteria: recovery from illness, it is normal that resting electrocardiogram recovers, and submaximal exercise test electrocardiogram transfers feminine gender to by the positive; Effectively, resting electrocardiogram or submaximal exercise test electrocardiogram ischemic ST decline, and go up more than 1.5 mV, but abnormal, or the T ripple that mainly leads shoals and reach more than 50%, or T ripple turn upright by smooth after treatment; Invalid, do not reach These parameters.

Clinical symptoms efficacy assessment standard: recovery from illness, cardiopalmus, the transference cure such as uncomfortable in chest; Effectively, cardiopalmus, the symptom such as uncomfortable in chest are improved; Invalid, symptom is unchanged or increase the weight of.

Model case.

Case [1] Chen, female, 26 years old, workman, on February 15th, 2002 is medical uncomfortable in chest, more than the cardiopalmus moon, and 6 days nasal obstructions of premorbid, watery nasal discharge pharyngalgia, fear of cold, takes SUXIAO GANMAO JIAONANG 4 days certainly, flu takes a turn for the better, but prominent sense is uncomfortable in chest, do not relax, and palpitation and uneasiness, Lai Wo institute checks: hear sounds is low blunt, and 78 beats/min of hearts rate are restrained not whole, 12 beats/min of news and premature beats, do not hear and pathologic murmur, and heart circle is without expansion; Electrocardioscopy: arrhythmia, frequent premature ventricular beats, part is premature ventricular beat, intends being diagnosed as viral myocarditis and hospitalizes hospital, western medical treatment 1 month, took inosine, rhythm of the heart equality medicine, symptom is improved, but ventricular premature contraction still can not control, rear inactive Western medicine, oral mind calming capsule 21 days, premature beat disappears; Follow up a case by regular visits to 1 year, not recurrence.

Case [2] Zhang, female, 36 years old, with " paroxysmal nervous uncomfortable 3 days ", be chief complaint, medical on October 14th, 2005, now medical before 2 days, prominent sense is nervous, more so, can not fall asleep night, and easily frightened, after have outbreak, then hospital admission repeatedly.Disease see paroxysmal cardiopalmus, easily frightened, sleep is poor, red tongue, white and thin fur, thready pulse; Holter shows 78 beats/min of average heart rates, artrial premature beat totally 213 times, ventricular premature contraction totally 7200 times; Myocardium enzyme, myocardial injury markers, rabat, Color Sonography, thyroid function, electrolyte inspection, all do not look into and see extremely; Western medicine diagnose is arrhythmia (functional ventricular premature beat), and tcm diagnosis is cardiopalmus (deficiency of both QI and blood), the rule for the treatment of: benefiting QI and nourishing blood, and surely throb with fear and calm the nerves; Give mind calming capsule 1.0g, 3 times/day, oral, by cardiopalmus after 3 days, there is obvious alleviation, after 7 days, sense is not nervous, and sleep can; Check Holte r: sinus rhythm, 68 beats/min of average heart rates, 58 beats/min of the slowest hearts rate, are sinus bradycardia, 106 beats/min of the fastest hearts rate, are sinus tachycardia, have no premature beat.

Case [3] Liu, male, 7 years old, to find that ventricular premature contraction is chief complaint for more than 1 year, on February 9th, 2008, carry out out-patient treatment, before 1 year, infant is looked into ECG and is found that frequent premature ventricular beats, its mother tell that to feel gas after infant activity tight when kindergarten health check-up, and local hospital is advised to front three hospital admission; Look into creatine kinase isozyme (CK-MB) 68U/L, creatine kinase (CK) 368 U/L, but negative troponin, Myoglobin is positive, and ECG shows frequent premature ventricular beats, is premature ventricular beat, and in conjunction with having flu history before, is diagnosed as viral myocarditis; Give propafenone, metoprolol (metoprolol), coenzyme Q10, enalapril treatment 1 year, but during every because of upper respiratory tract infection or by propafenone decrement, drug withdrawal, ventricular premature contraction number of times increases, and symptomatic recurrence increases the weight of, and repeatedly looks into ECG and show frequent premature ventricular beats; Holter shows: sinus rhythm, ventricular premature contraction, visible ventricular fusion beats, coupling interval not etc., every hour around the clock premature beat number of times difference not statistically significant; Because its arrhythmia easily recurs, simple western medicine therapeutic effect is not good, therefore for asking Chinese traditional treatment to carry out outpatient clinic; After its female Dai Shu infant activity, gas is tight, and repeated cold, haves a medical check-up and see pharyngeal congestion, the enlargement of tonsil III degree, and light red tongue, white and thin fur, regularly intermittent pulse, Western medicine diagnose is Myocarditis sequela, tcm diagnosis is " cardiopalmus " (deficiency of both vital energy and Yin); The rule for the treatment of: nourishing YIN and benefiting blood, benefiting vital QI for tranquillizing; On the basis of oral coenzyme Q10, metoprolol and propafenone, add with mind calming capsule 0.5g, tid, oral; With examining this side plus-minus, take after 3 months for a long time, because of repeatedly pulse-taking, cardiac auscultation and electrocardiogram no abnormality seen, the propafenone of stopping using, after still adhere to taking mind calming capsule, metoprolol and coenzyme Q10 3 months, look into normal ECG during further consultation at every turn; Holte r check is shown: sinus rhythm, and average heart rate 73/min, the slowest heart rate 57/ minute, the fastest heart rate 141/ minute, whole process has no premature beat; Color Sonography has no Secondary cases heart change; After existing infant conventional activity degree, do not feel special discomfort, have a medical check-up and see the enlargement of tonsil II degree, but reduce to some extent, nutritional development is good, and its family members are to treating satisfaction.

Claims

1. mind calming capsule, it is characterized in that: its composition is 30 grams of Radix Ginsengs, 30 grams of Radix Codonopsis, 30 grams of Radix Scrophulariae, 30 grams of Radix Salviae Miltiorrhizaes, 30 grams of Radix Sophorae Flavescentiss, 10 pieces, Fructus Jujubae, its manufacture method is: by 30 grams of Radix Ginsengs, 30 grams of Radix Codonopsis, 30 grams of Radix Scrophulariae, 30 grams of Radix Salviae Miltiorrhizaes, 30 grams of Radix Sophorae Flavescentiss, 10 pieces of selected impurity that remove of Fructus Jujubae, Removing Kernel for Date, artificial drying, dried Six-element Chinese medicine powder is broken into 80 order fine powders and mixes thoroughly, incapsulate.

2. mind calming capsule according to claim 1, is characterized in that: described capsule model is No. 0, and every capsules is 0.5 gram containing medicated powder amount.