Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine water-honeyed pill and preparation method for the treatment of gout, all select natural Chinese medicinal herb, can effectively treat gout.
Technical scheme of the present invention is: a kind of Chinese medicine water-honeyed pill for the treatment of gout, it is characterized in that, by the crude drug of following weight, make its effective ingredient: 30 grams of Rhizoma Smilacis Glabraes, 20 grams of the Radixs Astragali, 20 grams of Radix Achyranthis Bidentataes, 20 grams of Rhizoma Polygoni Cuspidati, 15 grams of Caulis Spatholobis, 15 grams of Radix Angelicae Sinensis, 15 grams of Rhizoma Alismatis, 15 grams, Rhizoma Curcumae Longae, 15 grams of Radix Gentianae Macrophyllae, 15 grams of Radix Salviae Miltiorrhizaes, 15 grams of Radix Clematidis, 10 grams of Radixs Stephaniae Tetrandrae, 10 grams of Rhizoma Et Radix Notopterygiis, 10 grams of Oletum Trogopteroris, 15 grams of Rhizoma Chuanxiongs, 10 grams of Myrrhas, 10 grams of Semen Sinapis Albaes, 10 grams of Bombyx Batryticatus, 10 grams of Cortex Moutans, 10 grams of Cortex Phellodendris, 10 grams of Fructus Liquidambaris, 12 grams of Radix Bupleuri, 10 grams of Fructus Aurantii Immaturuss, 10 grams of Rhizoma Cyperis, 10 grams of Radix Curcumaes, 10 grams of Ramulus Cinnamomi, 10 grams of Radix Aconitis, 6 grams, Semen Persicae, 6 grams, Flos Carthami.
Preparation method:
1, the medicinal powder beater of above-mentioned raw materials is broken into fine powder;
2, with high heat Mel is endured and boiled, then change slow fire into and endure slowly, raw honey heating is endured to boil to foam be light red gloss;
3, medicated powder is mixed by the mass ratio of 1:1 with the refined honey of having refined.While closing medicine, Mel adds while hot, fully, with even, makes its color and luster consistent, neither too hard, nor too soft, arbitrarily kneading model.
4, the medicine of the dough sample getting togather is placed, spice is mixed with honey component and moisten, and use full automatic machine for producing pills pill after producing certain viscosity.
5, treat pill diaphoresis, appearance hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell etc., is stored in shady and cool dry place.
Instructions of taking:
Each serving with 15, three times on the one, each one after each meal.It within 20 days, is a course for the treatment of.
The pharmacological action of each Chinese medicine:
Rhizoma Smilacis Glabrae: sweet, light, flat.Return liver, stomach warp.Dehumidifying, removing toxic substances, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, the limbs contracture due to syphilis and mercurialism, bones and muscles pain.
The Radix Astragali: warm in nature, sweet in the mouth.Tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.Cure mainly weakness of the spleen and stomach, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
Radix Achyranthis Bidentatae: sweetness and bitterness acid, flat.Enter liver, kidney channel.Raw dissipating blood stasis blood, the subduing inflammation used.Control gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury.Ripe in invigorating the liver and kidney, bone and muscle strengthening.Control waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.
Rhizoma Polygoni Cuspidati: micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea , mass in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.
Caulis Spatholobi: bitter, micro-sweet, temperature; Return Liver Channel.Enrich blood and invigorate blood circulation, dredge the meridian passage.This product abnormal smells from the patient is soft, walks to keep and has both, and can change cloudy hemopoietic, promoting the flow of QI-blood by warming the meridian, and promoting blood circulation to remove obstruction in the collateral, pushes away Chen Zhixin, embellishes but not dry, tonify without causing stagnation, row and mend broken feature, to the rheumatic arthralgia due to blood deficiency, all cards of stasis pain and gynecological, all have good effect.
Rhizoma Alismatis: sweet, cold.Enter kidney, urinary bladder channel.Diuretic, eliminating dampness by diuresis, expels the heat-evil.Control dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.
Rhizoma Curcumae Longae: removing blood stasis, circulation of qi promoting, stimulates the menstrual flow, pain relieving.Control trusted subordinate's feeling of fullness distending pain, brachialgia , mass in the abdomen, women's blood stasis amenorrhea, puerperal, the stasis of blood was stopped stomachache, injury from falling down, carbuncle.
Radix Gentianae Macrophyllae: expelling wind and removing dampness, and blood relaxing muscles and tendons, clearing away heat and promoting diuresis.Dispelling the wind and dampness pathogens arthralgia pain; Muscles and bones contracture, jaundice, has blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.
Radix Salviae Miltiorrhizae: hardship, is slightly cold; GUIXIN, Liver Channel.Activating blood circulation to dissipate blood stasis, removing heat from blood mind calming.This product is fallen and promoting the circulation of blood, is apt to into blood system, can qualcomm meridian, change stasis, clearing away heart-fire, removing heat from blood heat, and the will of calming the nerves, tired except throbbing with fear, is usually used in obstruction of qi in the chest and cardialgia, and menstruation portion adjusts, skin infection swells and ache, insomnia and the congestion disease such as swell and ache.
Radix Clematidis: pungent salty, temperature, poisonous.Enter urinary bladder channel.Wind-damp dispelling, the meridian dredging, expectorant saliva, the loose hypochondriac lump.Control gout, insensitive impediment, chills and pain of the waist and kness , , lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Radix Stephaniae Tetrandrae: hardship, cold.Return bladder, lung meridian.Inducing diuresis to remove edema, wind-expelling pain-stopping.For edema beriberi, dysuria, eczema sore, rheumatic arthralgia; Hypertension.
Rhizoma Et Radix Notopterygii: cold expelling, dispel the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Oletum Trogopterori: bitter sweet, temperature.Enter liver, spleen channel.Life promoting the circulation of blood pain relieving.Control all pains of trusted subordinate's vim and vigour, women's amenorrhea, postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Myrrha: hardship, pungent, flat, nontoxic.Liver, spleen, the heart, kidney channel.The analgesic therapy of invigorating blood circulation, detumescence and promoting granulation, cures mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, skin infection does not close up after bursting for a long time.
Semen Sinapis Albae: pungent, warm, return lung meridian.Warming the lung eliminating stagnation, inducing menstruation to relieve menalgia.The pungent wet of this product is sharp.Cough eliminating phlegm and prolong, promoting the circulation of QI machine, chest pain, the meridian dredging, all stagnation of phlegm stagnation of QIs, the stagnant meridians of cough with dyspnea hypochondriac pain or expectorant, the cards such as limbs pain, all can compatibility application.
Bombyx Batryticatus: bring down a fever, cough-relieving, reduces phlegm, calm relieving convulsion, detumescence, and regulate nerve, participate in lipid metabolism.
Cortex Moutan: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, and amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.
Cortex Phellodendri: hardship, cold.Enter kidney, urinary bladder channel.Heat clearing away, dampness, pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, osteopyrexia and fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Fructus Liquidambaris: bitter and puckery flavor, property is flat, nontoxic.Current 12 warps.Dispelling wind and removing obstruction in the collateral, diuretic dehumidifying.Control limbs arthralgia pain, contracture of the limbs, stomachache, edema, distension, amenorrhea, breast is few, carbuncle, anal fistula, scabies, eczema.
Radix Bupleuri: pungent, micro-hardship, be slightly cold; Return liver, gallbladder meridian.Induce sweat and bring down a fever, soothing liver-QI for relieving depression, elevate a turnable ladder yang-energy.This product is dredged and to be reached thoroughly kindly, is longer than and discongests stagnant heat in the liver and gall, again can depressed liver-energy dispersing and QI regulating, and be pain over the hypochondriac region key medicine due to treatment stagnant heat in the liver and gall, stagnation of QI due to depression of the liver.
Fructus Aurantii Immaturus: hardship, cold.Enter spleen, stomach warp.Dispelling the stagnated QI, loose painful abdominal mass, rushes down expectorant, removing food stagnancy.Control distension and fullness of the chest and abdomen, the thoracic obstruction, painful abdominal mass pain, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis.
Rhizoma Cyperi: pungent micro-hardship is sweet, flat.Enter liver, tri-jiao channel.The resolving depression of regulating the flow of vital energy, pain relieving regulating menstruation.Treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.
Radix Curcumae: arduous, cool.Enter the heart, lung, Liver Channel.Promoting QI circulation for relieving depression, removing heat from blood removing blood stasis with potent drugs, controls all pains of breast abdomen side of body rib, loses the heart demented, calentura coma. spit blood, and jaundice.
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Aconiti: expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Flos Carthami: promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
The present invention is by after above drug regimen, and drug effect has synergism, plays the effect of promoting blood circulation to remove obstruction in the collateral, removing damp-heat, removing pathogenic heat from blood and inducing diuresis, the liver soothing and the spleen invigorating.This kind treated the Chinese medicine water-honeyed pill of gout can effectively treat gout, and taking convenience, solved the inconvenience that Chinese medicine needs every day and decocts medicinal herbs, and safety has no side effect.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
Clinical observation
1, clinical data: be selected from the outpatient service in year June in July, 2012 to 2013 and patient with gout totally 94 examples of being in hospital, patient age is between 28-59 year, 46.5 years old mean age.
2, the diagnostic criteria of gout:
(1) joint of outbreak is red, swollen, hot, bitterly repeatedly, and typical parts is sufficient metatarsophalangeal joints, and other comprises ankle, knee joint, wrist, elbow, metacarpophalangeal joints etc.Course of disease elder can have joint deformity, arthroedema, periarticular or auricle portion tophus to form, and after calculus ulceration, can overflow white urate crystal, in hydrarthrosis, also can detect urate crystal.Outbreak is often with General Symptomies such as fear of cold heating, headache, whole body discomforts.
(2) be more common in, elderly men, overweight or overweight people is in the majority.
(3) blood uric acid is generally greater than 380 μ mol/L(6.4mg/dl).
(4) urine uric acid discharge capacity increases, and easily forms urate calculus and gouty nephropathy, and course of disease person of a specified duration causes renal hypofunction.
(5) pathological changes joint x-ray is taken the photograph the rounded or irregular punched-out defect district of the visible articular surface of sheet, and local sclerotin can have osteoporosis to change.Pyelography or B-type ultrasonography prompting renal calculus exist.
(6) get rid of arthritis and the secondary gout of other reasons.
3, Therapeutic Method: oral the present invention treats the Chinese medicine water-honeyed pill of gout, takes at twice sooner or later.It within 1 month, is 1 course for the treatment of.
4, criterion of therapeutical effect:
Cure: the joint transference cure of gout, clinical verification disappears.In blood and urine, uric acid content is normal, and normal renal function is followed up a case by regular visits to above nothing recurrence in 2 years continuously.
Take a turn for the better: remission.In blood and urine, uric acid content approaches normally, and renal function takes a turn for the better.
Invalid: symptom is without alleviation, and in blood and urine, uric acid content has no reduction, and renal function has no improvement.
5, therapeutic outcome: 94 routine patients take we and treat after 3 courses for the treatment of, cure 84 examples, 9 examples that take a turn for the better, invalid 1 example.Cure rate is 89.4%, and total effective rate reaches 98.9%.
In sum, the present invention is used for the treatment of the Chinese medicine water-honeyed pill of gout, through clinical trial, shows that it can effectively suppress the development of gout, improves patient's symptom, sign, evident in efficacy.
Model case:
Case one: goldenrain tree, man, 45 years old.Suffer from gouty arthritis, gouty calculus 5 years, the Western medicine such as informal dress Colchicum autumnale is salty, indometacin, the state of an illness is not felt any better, whenever suffering from cold and overworking, night right crus of diaphragm thumb fat start pain then spread all over the whole body arthralgia, painful abnormal, by one the friend of rehabilitation introduce, after the course for the treatment of of Chinese medicine water-honeyed pill treatment of taking that the present invention treats gout, red and swollen disappearance; Continue after two courses for the treatment of of medication, disease all disappears, and it is normal that blood uric acid recovers, and every test rating is all normal, drug withdrawal.The recurrence of following up a case by regular visits to that so far there are no.
Case two: hair so-and-so, man, 41 years old.Patient is whole body trick redness and swelling of joints, hurt like hell before 3 years, stands up daily life and all has any problem.Through local hospital inspection, acute gouty arthritis is suffered from diagnosis, takes a large amount of Western medicine, treatment by Chinese herbs, and the state of an illness is not controlled.After take the Chinese medicine water-honeyed pill that the present invention treats gout, taken after the course for the treatment of, can walk down, other symptoms are also clearly better, rear having taken continuously 2 courses for the treatment of, all transference cures, blood uric acid also recovers normal level, so far there are no recurrence.