CN103690861B - Anti-inflammatory medicament and manufacturing method thereof - Google Patents
Anti-inflammatory medicament and manufacturing method thereof Download PDFInfo
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- CN103690861B CN103690861B CN201310717803.4A CN201310717803A CN103690861B CN 103690861 B CN103690861 B CN 103690861B CN 201310717803 A CN201310717803 A CN 201310717803A CN 103690861 B CN103690861 B CN 103690861B
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- 230000003110 anti-inflammatory effect Effects 0.000 title abstract description 26
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Abstract
The invention relates to the field of medicines and particularly relates to an anti-inflammatory medicament and a manufacturing method thereof. The manufacturing method of the anti-inflammatory medicament comprises the following steps: mixing streptocaulon griffithii, scarlet kadsura root, Chinese knotweed root and peppermint in fixed parts by weight to obtain a mixture; calcining and stir-frying the mixture to carbonize 1/3 of the mixture to obtain the mixture after carbonization; soaking the mixture after carbonization, as well as the fixed weight of incised notopterygium rhizome and doubleteeth pubescent angilica root in the fixed weight of rice wine to obtain a solid-liquid mixture in which pharmaceutical ingredients are dissolved; filtering the solid-liquid mixture to obtain the anti-inflammatory medicament. The anti-inflammatory medicament can be used for diminishing inflammation by being applied on an affected part; as all components are natural Chinese herbal medicines, the anti-inflammatory medicament has no side effects against an organism; when the anti-inflammatory medicament is used for diminishing inflammation of the organism, compared with the operation of using an antibiotic to diminish the inflammation in the prior art, the risk of causing adverse reactions to the organism by the medicament is reduced.
Description
Technical field
The present invention relates to field of medicaments, in particular to a kind of antiphlogistic and its making side
Method.
Background technology
In medical domain, for the inflammation that scald, burn, wound and running sore etc. cause,
In the related art, anti-inflammatory is carried out by the way of antiphlogistic for oral administration more than people, and reaches and control
More purpose.For example, people generally carry out anti-inflammatory using the substantial amounts of antibiotic of injection.
In the related art, although antibiotic can play certain anti-inflammatory effect to all kinds of inflammation
Really；But, the substantial amounts of antibiotic of long-term taking, it can cause various bad anti-to body
Should, such as resistivity of toxic reaction, allergic reaction, suprainfection and reduction body
Deng；Therefore, in the related art, using the operation for carrying out to body injection of antibiotics anti-inflammatory
In the presence of risk higher.
The content of the invention
It is above-mentioned to solve the problems, such as it is an object of the invention to provide a kind of antiphlogistic.
It is another object of the present invention to provide a kind of preparation method of antiphlogistic.
A kind of antiphlogistic is provided in an embodiment of the present invention, in parts by weight, its
Material component includes：
3-5 parts of horse lotus saddle, kadsura root 3-5 parts, fiery 3-5 parts of carbon mother, peppermint 3-5 parts,
Ginger lives 1-3 parts, levisticum 1-3 parts and rice wine 90-110 parts；
Optionally, in parts by weight, its material component includes：
3.5-4.5 parts of horse lotus saddle, kadsura root 3.5-4.5 parts, it is fiery 3.5-4.5 parts of carbon mother, thin
Lotus 3.5-4.5 parts, 1.5-2.5 parts, levisticum 1.5-2.5 parts and rice wine 95-105 parts of ginger work；
Optionally, the formulation of the antiphlogistic is tincture；
Optionally, the alcoholic strength of the rice wine is 55 ° -65 °；
Antiphlogistic provided in an embodiment of the present invention, its component contains a variety of Chinese medicine composition, its
In, horse lotus general term for saddle and stirrups has preferable antiinflammation.Kadsura root, it is its taste is pungent, warm in nature, have
The promoting flow of qi and blood circulation, wind-expelling pain-stopping function.Fiery carbon mother cures mainly clearing heat and detoxicating, dampness removing and disappears stagnant, cool blood
Antipruritic, removing nebula, it can be used to treat inflammation（Mumps, tonsil
Inflammation, sphagitis, enteritis, dermatitis and traumatic injury etc.）.Peppermint is a kind of food and medicament dual-purpose material,
It has the effect of good anti-inflammatory heat-clearing.Ginger live have relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness and
Effect of analgesic.The work(that levisticum has wind-cold-dampness arthralgia, wind-dispelling, wins wet, cold dispelling and analgesic
Effect.By above-mentioned component according to the ratio of set weight with the rice wine mixing merged with set weight
Afterwards, the active drug composition of each component is dissolved in rice wine, so obtain have disappear well
The antiphlogistic of scorching effect.The antiphlogistic can take affected part and carry out anti-inflammatory by wiping, due to each component
It is natural Chinese herbal medicine, therefore body is free from side effects, is using the antiphlogistic to machine
During body anti-inflammatory, its with the prior art by using the operation of antibiotic anti-inflammatory compared with, reduce
Medicine can cause to body the risk of adverse reaction.
A kind of preparation method of antiphlogistic that the present invention is provided, comprises the following steps：
The horse lotus saddle of set parts by weight, kadsura root, Chinese knotweed and peppermint are mixed, is obtained
To mixture；
The mixture is calcined and fried so that described 1/3 mixture carbonization, is obtained
Mixture after to carbonization；
Mixture, the ginger work of set weight and levisticum after the carbonization are put into set weight
Rice wine in soak, obtain the solidliquid mixture dissolved with drug ingedient；
By solidliquid mixture filtering, antiphlogistic is obtained；
Optionally, the mixture is calcined and fried described so that 1/3 mixing
Thing be carbonized, after be carbonized the step of mixture in, the temperature being calcined and fried be 55 DEG C -65 DEG C；
Optionally, it is described by the carbonization after mixture, set weight ginger live and levisticum
Input is soaked in the rice wine of set weight, obtains solidliquid mixture dissolved with drug ingedient
Specifically included in step：Mixture, the ginger work of set weight and levisticum after the carbonization are thrown
Enter the alcoholic strength to set weight to be soaked in 55 ° of -65 ° of rice wine, obtain solidliquid mixture；
Optionally, it is described by the carbonization after mixture, set weight ginger live and levisticum
The alcoholic strength to set weight is put into be soaked in 55 ° of -65 ° of rice wine, solid-liquid mixing is obtained
In the step of thing, the time of the immersion is 120-140 days；
Optionally, described by solidliquid mixture filtering, the step of obtain antiphlogistic in,
Specifically include：After the solidliquid mixture is stood into 2-3 days, filtered, obtained anti-inflammatory
Medicine；
Optionally, it is described by the solidliquid mixture stand 2-3 days after, filtered,
In the step of obtaining antiphlogistic, described stand the solidliquid mixture specifically includes for 2-3 days：
The solidliquid mixture is stood 2-3 days under conditions of 22 DEG C -28 DEG C.
By the above method be capable of achieving by different raw materials be made can external application anti-inflammatory
Medicine.
Brief description of the drawings
Fig. 1 shows the flow chart of the antiphlogistic that the embodiment of the present invention two is provided.
Specific embodiment
Do further detailed to the present invention below by specific embodiment and with reference to accompanying drawing
Description.
Embodiment one
A kind of antiphlogistic is provided in an embodiment of the present invention, in parts by weight, its
Material component includes：
3-5 parts of horse lotus saddle, kadsura root 3-5 parts, fiery 3-5 parts of carbon mother, peppermint 3-5 parts,
Ginger lives 1-3 parts, levisticum 1-3 parts and rice wine 90-110 parts.
Antiphlogistic provided in an embodiment of the present invention, its component contains a variety of Chinese medicine composition, its
In, horse lotus general term for saddle and stirrups has preferable antiinflammation.Kadsura root, it is its taste is pungent, warm in nature, have
The promoting flow of qi and blood circulation, wind-expelling pain-stopping function.Fiery carbon mother cures mainly clearing heat and detoxicating, dampness removing and disappears stagnant, cool blood
Antipruritic, removing nebula, it can be used to treat inflammation（Mumps, tonsil
Inflammation, sphagitis, enteritis, dermatitis and traumatic injury etc.）.Peppermint is a kind of food and medicament dual-purpose material,
It has the effect of good anti-inflammatory heat-clearing.Ginger live have relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness and
Effect of analgesic.The work(that levisticum has wind-cold-dampness arthralgia, wind-dispelling, wins wet, cold dispelling and analgesic
Effect.By above-mentioned component according to the ratio of set weight with the rice wine mixing merged with set weight
Afterwards, the active drug composition of each component is dissolved in rice wine, so obtain have disappear well
The antiphlogistic of scorching effect.The antiphlogistic can take affected part and carry out anti-inflammatory by wiping, due to each component
It is natural Chinese herbal medicine, therefore body is free from side effects, is using the antiphlogistic to machine
During body anti-inflammatory, its with the prior art by using the operation of antibiotic anti-inflammatory compared with, reduce
Medicine can cause to body the risk of adverse reaction.
Preferably, in parts by weight, its material component includes：
3.5-4.5 parts of horse lotus saddle, kadsura root 3.5-4.5 parts, it is fiery 3.5-4.5 parts of carbon mother, thin
Lotus 3.5-4.5 parts, 1.5-2.5 parts, levisticum 1.5-2.5 parts and rice wine 95-105 parts of ginger work；Press
According to the antiphlogistic of above-mentioned preferred proportioning composition, its anti-inflammatory effects is more preferably.
In the present embodiment, the antiphlogistic for being matched according to various material components is tincture,
Tincture can be very good as a kind of formulation of externally applied anti-inflammation medicine.
Additionally, in the present embodiment, it is preferred that in order that after obtaining each group distribution ratio, its
Contained effective component substantial amounts of can be dissolved in rice wine, it is preferred that the alcoholic strength of rice wine is
55°-65°。
In order that the antiphlogistic for obtaining the embodiment of the present invention one is preferably applied, it is more efficient
During being applied to anti-inflammatory, the present invention is also provided on the basis of above-described embodiment one
Embodiment two, embodiment two is the treatment method enumerated to the antiphlogistic that embodiment one is provided,
Now it is described in detail and explains, refer to Fig. 1：
Embodiment two
The preparation method of Chinese medicine preparation provided in an embodiment of the present invention is comprised the following steps：
Step 101：By the horse lotus saddle of set parts by weight, kadsura root, Chinese knotweed and thin
Lotus mixes, and obtains mixture；
In a step 101, the components such as horse lotus saddle, kadsura root, Chinese knotweed and peppermint are mixed
Need to be calcined and fried after conjunction, to remove substantial amounts of moisture.
Step 102：The mixture is calcined and fried so that described 1/3 mixing
Thing is carbonized, mixture after being carbonized；
In a step 102, by being calcined and fried, the large quantity of moisture in various medicine components can be taken off
Remove；It is also possible to so that the effective component contained in each component is separated out to a certain extent.
In this step, after 1/3 mixture is carbonized, completed by the operation being calcined and fried；
Additionally, in the present embodiment, during ensureing to be calcined and fried, will not cause that each component undergoes
Temperature too high and then the phenomenon of appearance gelatinization；The temperature being calcined and fried should be preferably controlled at 55 DEG C
- 65 DEG C, preferably 60 DEG C；Need to carry out slow fire heating during being calcined and fried；Specifically
, the thermal source for producing afterwards can be lighted by using the alcohol that alcoholic strength is 60 ° and is added
Heat.
Step 103：By mixture, the ginger work of set weight and levisticum input after the carbonization
Soaked into the rice wine of set weight, obtain the solidliquid mixture dissolved with drug ingedient；
In this step, mixture is lived and levisticum with the ginger of set weight after the carbonization that will be obtained
In input to the rice wine of set weight, soaked, and then obtain consolidating dissolved with drug ingedient
Liquid mixture；During immersion, the active ingredient contained by it can be dissolved in each medicine components
In rice wine, and then form the medicative solidliquid mixture of tool；Preferably, in this step,
In order to fully realize dissolving completely the active ingredient of medicine as far as possible, it is preferred that immersion
Time can be 120-140 days, or rice wine alcoholic strength can be 55 ° -65 °, wine
Precision can be used as a kind of preferable organic solvent for 55 ° of -65 rice wine, and it can be by various groups
Effective component dissolving in part, and then form liquid；During immersion, it is however generally that,
The time of immersion can be controlled at 120-140 days, and so, it can cause the medicine in each component
Effect composition completely dissolves as far as possible.
Step 104：By solidliquid mixture filtering, antiphlogistic is obtained；
It is capable of achieving to separate the slag in solidliquid mixture, liquid by step 104, slag can be lost
Abandon, liquid is then as the antiphlogistic of the present embodiment.Additionally, it is preferred that, in this step,
Before filtration, the solidliquid mixture is preferably stood 2-3 days so that substantial amounts of fine slag
Precipitate as far as possible, preferably to realize the effect that slag, liquid are separate.Meanwhile, standing
During, in order to ensure that drug effect will not be reduced, it is preferred that should stand at normal temperatures（22℃
-28℃）.
Embodiment three：
The present embodiment is provided and combines above-mentioned two embodiment there is provided specific 3 examples, its
In, in three examples, the weight of every part of above-described embodiment can be specially 1 jin.
Example 1, the horse lotus saddle that weight is 2 kilograms, kadsura root, Chinese knotweed and thin
Lotus mixes, and obtains mixture；The mixture is calcined and fried so that 1/3 it is described mixed
Compound is carbonized, mixture after being carbonized；Mixture, weight after the carbonization are 1
Kilogram ginger live and levisticum put into the rice wine that weight is 50 kilograms immersion 130 days, obtain
Dissolved with the solidliquid mixture of drug ingedient；The solidliquid mixture is quiet under conditions of 25 DEG C
Filtered after putting 3 days, remove solid-state slag, obtain antiphlogistic.
Example 2, horse lotus saddle, kadsura root, Chinese knotweed and peppermint that weight is 3 jin
Mixing, obtains mixture；The mixture is calcined and fried so that 1/3 mixing
Thing is carbonized, mixture after being carbonized；Mixture, weight after the carbonization are 1.5
Jin ginger live and levisticum put into the rice wine that weight is 90 jin immersion 120 days, obtain dissolved with
The solidliquid mixture of drug ingedient；The solidliquid mixture is stood 2 under conditions of 22 DEG C
Filtered after it, remove solid-state slag, obtain antiphlogistic.
Example 3, horse lotus saddle, kadsura root, Chinese knotweed and peppermint that weight is 5 jin
Mixing, obtains mixture；The mixture is calcined and fried so that 1/3 mixing
Thing is carbonized, mixture after being carbonized；Mixture, weight after the carbonization are 2.5
The ginger of jin lives and levisticum puts into the rice wine that weight is 110 jin immersion 140 days, obtains molten
There is the solidliquid mixture of drug ingedient；The solidliquid mixture is stood under conditions of 28 DEG C
Filtered after 3 days, remove solid-state slag, obtain antiphlogistic, obtain antiphlogistic.
It is below the specific case of the antiphlogistic being made up of above-described embodiment：
After antiphlogistic with this example 1-3 offers, the patient for being burnt or being scalded is in 3-7
Rehabilitation in it；Patient containing running sore rehabilitation in 3-7 days；By the urine institute injury of spider
Person's rehabilitation in 2-4 days, outer wound hinders patient's rehabilitation in 4-15 days.
Case 1
In November, 2003 day, present inventor is in construction site by 380 volt of 42 core
Copper core cable has burnt the left hand palm in centre of the palm short circuit.Present inventor is left in 9 thirty
Right that the palm burnt is soaked in anti-inflammatory medicine of the present invention, pain disappears at once.Leaching
Bubble removes powder thirty in the afternoon 16 to handle after, and pain does not have substantially.Again with absorbent cotton,
Gauze twines the palm of burn（Protection affected part is in order to avoid secondary injury）, with liquid medicine of the invention
Slowly gone up with liquid medicine moisturizing toward absorbent cotton（Many times of daily 6-10）, fully recovered after 7 days.Extremely
The present is without scar.
Case 2
The day of in September, 2004, patient 1 to get up do not worn the clothes also after washing one's face and rinsing one's mouth and just go opening also
There is no the pressure cooker of pressure release（It is the gruel of boiling in pot）.As a result pot cover flies out, boiling it is dilute
Congee has splashed the half body of patient 1.Patient 1 applies after dry towel is soaked with liquid medicine of the invention
Affected part, patient's recovery from illness after clock more than 3 points in afternoon.
Case 3
The swelling face that the patient of November one in 2004 has a running sore, running sore at the thigh of left side has
More than ten centimeters wide, and shinny height is convex on sore top.Patient was smeared in evening on the same day with the liquid medicine of the application
6-8 times.Morning, running sore reduces, and sore top is sagging no longer shinny, and Surrounding muscles are extensive
Complex elasticity, the liquid medicine for persistently smearing the application is fully recovered after 4 days.
Case 4
One night in November, 2007, three years old patient 2 prepare have supper when,
Imprudence is fallen down and supports enter in the chaffy dish pot of boiling right hand elbow.Patient 2 is using traditional
After antiphlogistic is treated 4 days, affected part is red and swollen serious and opens this and festers a bit.After use the present invention instead
Liquid medicine is treated.Medication that night（Smear 8-10 times）, the affected part inflammation of patient 2 substantially mitigates,
Second day, affected part was no longer rubescent hot（Inflammation mitigates）, continue every the topical application of drug in 1-2 hours.
3rd day, routed place opened this apocenosis, and affected part is no longer red and swollen.4th day, affected part incrustation, affected part
It is no longer red and swollen.This process continues medication, continues every the topical application of drug in 1-2 hours, after a week
Recovery from illness.
Case 5
In August, 2007, the left foot forefinger of patient 3 pounds disconnected half together with bone by machinery.To doctor
After institute's suture, transfusion bottle anti-inflammatory is played daily.10 days future troubles refer to that purple is black, and affected part has body fluid to overflow.
After liquid medicine of the invention（Every the topical application of drug in 1-2 hours）, body fluid no longer overflows within second day, wound
Form a scab.Continue every the topical application of drug in 1-2 hours, fully recovered after two weeks.
To sum up, this antiphlogistic that the present invention is provided is a kind of exterior-applied formulation, direct when using
Affected part is applied to, it is very convenient, it is very convenient during anti-inflammatory, no
There is injection（Injection of antibiotics）The risk of " rejection " brought to human body, greatly
Medical treatment cost is reduced, is saved trouble effortless.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention,
For a person skilled in the art, the present invention can have various modifications and variations.It is all
Within the spirit and principles in the present invention, any modification, equivalent substitution and improvements made etc.,
Should be included within the scope of the present invention.
Claims (9)
1. a kind of antiphlogistic, it is characterised in that in parts by weight, its raw material by with
Lower component composition：
3-5 parts of horse lotus saddle, kadsura root 3-5 parts, Chinese knotweed 3-5 parts, peppermint 3-5 parts,
Ginger lives 1-3 parts, levisticum 1-3 parts and rice wine 90-110 parts；
Its preparation method is comprised the following steps：
The horse lotus saddle of set parts by weight, kadsura root, Chinese knotweed and peppermint are mixed, is obtained
To mixture；
The mixture is calcined and fried so that 1/3 mixture carbonization, is obtained carbon
Mixture after change；
Mixture, the ginger work of set weight and levisticum after the carbonization are put into set weight
Rice wine in soak, obtain the solidliquid mixture dissolved with drug ingedient；
By solidliquid mixture filtering, antiphlogistic is obtained.
2. antiphlogistic according to claim 1, it is characterised in that according to weight portion
Number meter, its raw material is made up of following component：
3.5-4.5 parts of horse lotus saddle, kadsura root 3.5-4.5 parts, Chinese knotweed 3.5-4.5 parts, it is thin
Lotus 3.5-4.5 parts, 1.5-2.5 parts, levisticum 1.5-2.5 parts and rice wine 95-105 parts of ginger work.
3. antiphlogistic according to claim 1 and 2, it is characterised in that described to disappear
The formulation of scorching medicine is tincture.
4. antiphlogistic according to claim 3, it is characterised in that the rice wine
Alcoholic strength is 55 ° -65 °.
5. antiphlogistic according to claim 4, it is characterised in that described by institute
State mixture to be calcined and fried so that 1/3 mixture carbonization, mix after being carbonized
In the step of thing,
The temperature being calcined and fried is 55 DEG C -65 DEG C.
6. antiphlogistic according to claim 4, it is characterised in that described by institute
Mixture, the ginger work of set weight and levisticum are put into the rice wine of set weight after stating carbonization
Immersion, the step of obtain the solidliquid mixture dissolved with drug ingedient in specifically include：
Mixture, the ginger work of set weight and levisticum after the carbonization are put into set weight
Alcoholic strength to soak in 55 ° of -65 ° of rice wine, obtain the solid-liquid mixing dissolved with drug ingedient
Thing.
7. antiphlogistic according to claim 6, it is characterised in that described by institute
Mixture, the ginger work of set weight and levisticum are put into the alcoholic strength of set weight after stating carbonization
Be to be soaked in 55 ° of -65 ° of rice wine, the step of obtain solidliquid mixture in,
The time of the immersion is 120-140 days.
8. the antiphlogistic according to claim any one of 4-7, it is characterised in that
It is described by solidliquid mixture filtering, the step of obtain antiphlogistic in, specifically include：
After the solidliquid mixture is stood into 2-3 days, filtered, obtained antiphlogistic.
9. antiphlogistic according to claim 8, it is characterised in that described by institute
State after solidliquid mixture stands 2-3 days, filtered, the step of obtain antiphlogistic in,
Described stand the solidliquid mixture specifically includes for 2-3 days：
The solidliquid mixture is stood 2-3 days under conditions of 22 DEG C -28 DEG C.
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| CN1059327C (en) * | 1995-12-01 | 2000-12-13 | 王传义 | Inflammation diminishing and asthma stopping cream |
| CN1605353A (en) * | 2003-10-10 | 2005-04-13 | 段维和 | Liniment for diminishing inflammation and stopping pain and its preparation process |
| CN101108240A (en) * | 2006-07-17 | 2008-01-23 | 李辉 | Multipurpose pure traditional Chinese medicine externally used liquid for skin |
| CN101879301B (en) * | 2010-06-23 | 2011-09-07 | 党彬 | Chinese medicinal herb preparation for treating chronic cervicitis |
| CN102327513A (en) * | 2011-09-22 | 2012-01-25 | 郭心仪 | Traditional Chinese medicine for treating periodontitis |
| CN102657835B (en) * | 2012-05-23 | 2014-02-12 | 钟光荣 | Composition and medical liquor for treatment of high blood pressure/rheumatoid arthritis and preparation method and application of composition and medical liquor |
| CN103301407A (en) * | 2013-06-26 | 2013-09-18 | 陈黎光 | Ant wind dispelling essential oil liniment and preparation method thereof |
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