CN103690806A - External application medicament for treating facial paralysis and preparation and use methods thereof - Google Patents
External application medicament for treating facial paralysis and preparation and use methods thereof Download PDFInfo
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- CN103690806A CN103690806A CN201310683315.6A CN201310683315A CN103690806A CN 103690806 A CN103690806 A CN 103690806A CN 201310683315 A CN201310683315 A CN 201310683315A CN 103690806 A CN103690806 A CN 103690806A
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Abstract
The invention discloses an external application medicament for treating facial paralysis. The external application medicament comprises the following bulk drugs in parts by weight: 6-8 parts of cogongrass rhizome, 8-12 parts of poria cocos, 10-15 parts of platycodon root, 10-12 parts of white sandalwood, 10-20 parts of honeysuckle flower, 6-9 parts of cicada shell, 12-20 parts of tall gastrodia tuber, 10-13 parts of liquoric root, 6-9 parts of red-rooted salvia root and 10-15 parts of sugar candy. Compared with the prior art, the external application medicament has the advantages of remarkable medicinal effect, low price, no toxic or side effect, avoidance of drug tolerance of a patient and prevention of relapse, and is suitable for clinical application; preparation and use methods of the medicament are simple, convenient and feasible, and are independent of the technical contingency of medical personnel.
Description
Technical field
The present invention relates to Chinese medicine preparation and preparation method thereof, relate in particular to a kind of topical agent and preparation and application thereof of facial paralysis.
Background technology
Facial paralysis, also claims facial neuritis, facial paralysis, bell's palsy, hunter syndrome, is commonly called as " wapperijaw wind ", " facial paralysis ", " hanging skew wind " etc., is to take a kind of commonly encountered diseases that facial expression muscle group dyskinesia is principal character.The cause of disease of facial paralysis is still not very clear, thinks due to due to nervus facialis microcirculation disturbance more.Overtired, chilling after antiperspirant, viral infection, mental pressure, inherited genetic factors etc. can make people suffer from facial paralysis.Because the cause of disease is complicated, and indefinite, the method for the treatment of is also unified not to the utmost.Common Therapeutic Method has Drug therapy, naturopathy, treatment by Chinese herbs and acupuncture and moxibustion therapy etc.The multiplex hormone of Drug therapy, B vitamin, microcirculation improving agent bendazol, low molecular dextran etc.Conventional naturopathy has ultrashort wave, low mid-frequency current therapy, laser, medicine importing etc.Treatment by Chinese herbs has many ancient prescriptions, proved recipe, and as QIANZHENGSAN, eight tastes, to exempt from wind soup, Bel loose etc.In clinical practice, find, although above-mentioned Therapeutic Method has the case of producing effects, its scope of application is all fuzzyyer, and patient's selection is often more difficult, and many patients have expended mint of money in examination repeatedly in controlling, and have missed golden hour.Acupuncture and moxibustion therapy is one of Main Means of Chinese traditional treatment facial paralysis, but still disputable for the selection of Acupuncture opportunity plays, and it selects cave and maneuver also different, standardization level is low, occasionality and uncertainty are rather outstanding, harsher to doctor individual's requirement, are difficult to universal enforcement.
Summary of the invention
Goal of the invention: in order to solve the existing problem of prior art, the invention provides a kind of drug effect is remarkable, with low cost, be difficult for the facial paralysis of recurrence topical agent and preparation and application thereof.
Technical scheme: for achieving the above object, the present invention is by the following technical solutions: a kind of topical agent of facial paralysis, comprises the crude drug of following parts by weight: 6～8 parts of Rhizoma Imperataes, 8～12 parts, Poria, 10～15 parts of RADIX PLATYCODIs, 10～12 parts of Santalum albums, 10～20 parts of Flos Loniceraes, 6～9 parts of Periostracum Cicadaes, 12～20 parts, Rhizoma Gastrodiae, 10～13 parts, Radix Glycyrrhizae, 6～9 parts of Radix Salviae Miltiorrhizaes, 10～15 parts, crystal sugar.
As a further improvement on the present invention, described each crude drug consumption is composed as follows according to quality meter: the crude drug that comprises following parts by weight: 7 parts of Rhizoma Imperataes, 10 parts, Poria, 13 parts of RADIX PLATYCODIs, 11 parts of Santalum albums, 15 parts of Flos Loniceraes, 7 parts of Periostracum Cicadaes, 16 parts, Rhizoma Gastrodiae, 12 parts, Radix Glycyrrhizae, 8 parts of Radix Salviae Miltiorrhizaes, 13 parts, crystal sugar.
Above-mentioned facial paralysis the preparation method of topical agent, comprise the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Santalum album, Radix Salviae Miltiorrhizae, RADIX PLATYCODI, four kinds of crude drug mixing and water addings of Poria are soaked, water consumption is 2～4 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 25～30min is boiled in big fire, add Radix Glycyrrhizae, Flos Lonicerae, Rhizoma Gastrodiae, it is 20%～30% that rear continuation slow fire boiling to moisture in medicinal residues is boiled in big fire again;
(3) Rhizoma Imperatae, Periostracum Cicadae and crystal sugar are ground into powder after with after medicinal residues in step (2) mix, add the water of 2～4 times of gross weights to soak, after immersion 10min, big fire is boiled, continuation slow fire boiling to moisture in medicinal residues is 10%～15%;
(4) medicinal residues that step (3) obtained are ground to mud shape, obtain the topical agent of described facial paralysis.
Above-mentioned facial paralysis the using method of topical agent, wash away after the topical agent of described facial paralysis is coated on to facial 30min, before sleeping every day 1h and get up after 1h carry out at twice.
Beneficial effect: a kind of facial paralysis provided by the present invention preparation and the using method of topical agent, compared with prior art have the following advantages: drug effect is remarkable, cheap on the one hand, has no side effect, can not cause the dependency of patient to medicine, be difficult for recurrence; On the other hand and preparation and application simple and easy to do, do not rely on medical personnel's technology occasionality, be suitable for clinical practice.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described:
Embodiment 1:
A topical agent for facial paralysis, comprises the crude drug of following parts by weight: Rhizoma Imperatae 6,8 parts, Poria, 10 parts of RADIX PLATYCODIs, 10 parts of Santalum albums, 10 parts of Flos Loniceraes, 6 parts of Periostracum Cicadaes, 12 parts, Rhizoma Gastrodiae, 10 parts, Radix Glycyrrhizae, 6 parts of Radix Salviae Miltiorrhizaes, 10 parts, crystal sugar.
Above-mentioned facial paralysis the preparation method of topical agent, comprise the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Santalum album, Radix Salviae Miltiorrhizae, RADIX PLATYCODI, four kinds of crude drug mixing and water addings of Poria are soaked, water consumption is 2 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 25min is boiled in big fire, add Radix Glycyrrhizae, Flos Lonicerae, Rhizoma Gastrodiae, it is 20% that rear continuation slow fire boiling to moisture in medicinal residues is boiled in big fire again;
(3) Rhizoma Imperatae, Periostracum Cicadae and crystal sugar are ground into powder after with after medicinal residues in step (2) mix, add the water of 2 times of gross weights to soak, after immersion 10min, big fire is boiled, continuation slow fire boiling to moisture in medicinal residues is 10%;
(4) medicinal residues that step (3) obtained are ground to mud shape, obtain the topical agent of described facial paralysis.
Above-mentioned facial paralysis the using method of topical agent: after the topical agent of described facial paralysis is coated on to facial 30min, wash away, before sleeping every day 1h and get up after 1h carry out at twice.
Embodiment 2:
A topical agent for facial paralysis, comprises the crude drug of following parts by weight: 7 parts of Rhizoma Imperataes, 10 parts, Poria, 13 parts of RADIX PLATYCODIs, 11 parts of Santalum albums, 15 parts of Flos Loniceraes, 7 parts of Periostracum Cicadaes, 16 parts, Rhizoma Gastrodiae, 12 parts, Radix Glycyrrhizae, 8 parts of Radix Salviae Miltiorrhizaes, 13 parts, crystal sugar.
Above-mentioned facial paralysis preparation and the using method of topical agent, comprise the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Santalum album, Radix Salviae Miltiorrhizae, RADIX PLATYCODI, four kinds of crude drug mixing and water addings of Poria are soaked, water consumption is 3 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 28min is boiled in big fire, add Radix Glycyrrhizae, Flos Lonicerae, Rhizoma Gastrodiae, it is 25% that rear continuation slow fire boiling to moisture in medicinal residues is boiled in big fire again;
(3) Rhizoma Imperatae, Periostracum Cicadae and crystal sugar are ground into powder after with after medicinal residues in step (2) mix, add the water of 3 times of gross weights to soak, after immersion 10min, big fire is boiled, continuation slow fire boiling to moisture in medicinal residues is 13%;
(4) medicinal residues that step (3) obtained are ground to mud shape, obtain the topical agent of described facial paralysis.
Above-mentioned facial paralysis the using method of topical agent: after being coated on facial 30min, wash away, before sleeping every day 1h and get up after 1h carry out at twice.
Embodiment 3:
A topical agent for facial paralysis, comprises the crude drug of following parts by weight: 8 parts of Rhizoma Imperataes, 12 parts, Poria, 15 parts of RADIX PLATYCODIs, 12 parts of Santalum albums, 20 parts of Flos Loniceraes, 9 parts of Periostracum Cicadaes, 20 parts, Rhizoma Gastrodiae, 13 parts, Radix Glycyrrhizae, 9 parts of Radix Salviae Miltiorrhizaes, 15 parts, crystal sugar.
Above-mentioned facial paralysis preparation and the using method of topical agent, comprise the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Santalum album, Radix Salviae Miltiorrhizae, RADIX PLATYCODI, four kinds of crude drug mixing and water addings of Poria are soaked, water consumption is 4 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 30min is boiled in big fire, add Radix Glycyrrhizae, Flos Lonicerae, Rhizoma Gastrodiae, it is 30% that rear continuation slow fire boiling to moisture in medicinal residues is boiled in big fire again;
(3) Rhizoma Imperatae, Periostracum Cicadae and crystal sugar are ground into powder after with after medicinal residues in step (2) mix, add the water of 4 times of gross weights to soak, after immersion 10min, big fire is boiled, continuation slow fire boiling to moisture in medicinal residues is 15%;
(4) medicinal residues that step (3) obtained are ground to mud shape, obtain the topical agent of described facial paralysis.
Above-mentioned facial paralysis the using method of topical agent: after being coated on facial 30min, wash away, before sleeping every day 1h and get up after 1h carry out at twice.
By clinical case, further set forth below the beneficial effect of medicine of the present invention:
(1) clinical data and Therapeutic Method
With test group facial paralysis patient 50 examples, compare with matched group 50 examples.
test group:chinese drugs agentia described in embodiment 1-3 and using method in the present invention, continuous use 7 days is 1 course for the treatment of;
matched group:adopting conventional medicine to treat, every day three times, 7 days was 1 course for the treatment of.
Test group and matched group patient are fully recovered in 3 months and paid a return visit, investigate and record constipation disease recurrence.
(2) curative effect determinate standard
A) effective: after finishing the course for the treatment of, clinical symptoms is clearly better before treating, facial expression muscle recovers, catacleisis, and while talking and laugh, in nose, ditch and bicker are without crooked, and short-term is without recurrence;
B) effective: after finishing the course for the treatment of, facial muscle function is most of recovers normal;
C) invalid: symptom, without obviously alleviating, even increases the weight of.
(3) clinical effectiveness
Test group and the comparison of matched group curative effect, in Table 1.
Table 1 test group and the comparison of matched group curative effect
| ? | Effective | Effectively | Invalid | Add up to | Effective percentage (%) | Relapse rate (%) |
| Test group | 28 | 19 | 3 | 50 | 94 | 5 |
| Matched group | 10 | 13 | 27 | 50 | 46 | 45 |
Clinical effectiveness shows: test group facial paralysis patient 50 examples, total effective rate reaches in 94%, three month 5% relapse rate, with the total effective rate of matched group 50 examples 46% and in three months 45% relapse rate compare, be obviously better than matched group.Illustrate that Drug therapy facial paralysis of the present invention is evident in efficacy, drug effect is remarkable and be difficult for recurrence, has good promotional value.
Should be understood that, the above specific embodiment is only not used in and limits the scope of the invention for the present invention is described, after having read the present invention, those skilled in the art all fall within the application's claims limited range to the modification of the various equivalent form of values of the present invention.
Claims (4)
1. the topical agent of a facial paralysis, it is characterized in that, comprise the crude drug of following parts by weight: 6～8 parts of Rhizoma Imperataes, 8～12 parts, Poria, 10～15 parts of RADIX PLATYCODIs, 10～12 parts of Santalum albums, 10～20 parts of Flos Loniceraes, 6～9 parts of Periostracum Cicadaes, 12～20 parts, Rhizoma Gastrodiae, 10～13 parts, Radix Glycyrrhizae, 6～9 parts of Radix Salviae Miltiorrhizaes, 10～15 parts, crystal sugar.
Facial paralysis according to claim 1 topical agent, it is characterized in that, comprise the crude drug of following parts by weight: 7 parts of Rhizoma Imperataes, 10 parts, Poria, 13 parts of RADIX PLATYCODIs, 11 parts of Santalum albums, 15 parts of Flos Loniceraes, 7 parts of Periostracum Cicadaes, 16 parts, Rhizoma Gastrodiae, 12 parts, Radix Glycyrrhizae, 8 parts of Radix Salviae Miltiorrhizaes, 13 parts, crystal sugar.
Facial paralysis as claimed in claim 1 the preparation method of topical agent, it is characterized in that comprising the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) first Santalum album, Radix Salviae Miltiorrhizae, RADIX PLATYCODI, four kinds of crude drug mixing and water addings of Poria are soaked, water consumption is 2～4 times of four kinds of crude drug weight summations, after soaking 20min, rear slow fire continuation decoction 25～30min is boiled in big fire, add Radix Glycyrrhizae, Flos Lonicerae, Rhizoma Gastrodiae, it is 20%～30% that rear continuation slow fire boiling to moisture in medicinal residues is boiled in big fire again;
(3) Rhizoma Imperatae, Periostracum Cicadae and crystal sugar are ground into powder after with after medicinal residues in step (2) mix, add the water of 2～4 times of gross weights to soak, after immersion 10min, big fire is boiled, continuation slow fire boiling to moisture in medicinal residues is 10%～15%;
(4) medicinal residues that step (3) obtained are ground to mud shape, obtain the topical agent of described facial paralysis.
Facial paralysis as claimed in claim 1 the using method of topical agent, it is characterized in that, wash away after the topical agent of described facial paralysis is coated on to facial 30min, before sleeping every day 1h and get up after 1h carry out at twice.
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| CN201310683315.6A CN103690806B (en) | 2013-12-16 | 2013-12-16 | A kind of topical agent of facial paralysis and preparation and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115737764A (en) * | 2017-11-29 | 2023-03-07 | 河南中医药大学 | Traditional Chinese medicine for treating acute stage of peripheral facial paralysis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700364A (en) * | 2009-11-12 | 2010-05-05 | 张国营 | Thrombolytic and lipid-lowering pill |
| CN101744906A (en) * | 2008-12-01 | 2010-06-23 | 河北以岭医药研究院有限公司 | Applications of Chinese medicinal composition to preparation of medicament for treating facial paralysis |
| CN103142978A (en) * | 2013-03-22 | 2013-06-12 | 邓广博 | Medicine for treating peripheral facial paralysis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101744906A (en) * | 2008-12-01 | 2010-06-23 | 河北以岭医药研究院有限公司 | Applications of Chinese medicinal composition to preparation of medicament for treating facial paralysis |
| CN101700364A (en) * | 2009-11-12 | 2010-05-05 | 张国营 | Thrombolytic and lipid-lowering pill |
| CN103142978A (en) * | 2013-03-22 | 2013-06-12 | 邓广博 | Medicine for treating peripheral facial paralysis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115737764A (en) * | 2017-11-29 | 2023-03-07 | 河南中医药大学 | Traditional Chinese medicine for treating acute stage of peripheral facial paralysis and preparation method thereof |
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