CN101732577B

CN101732577B - Medicament for treating Meniere's disease

Info

Publication number: CN101732577B
Application number: CN200810159725XA
Authority: CN
Inventors: 李会平; 郭辉荣; 王泰峰; 郑玉芬; 左凯
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-11-06
Filing date: 2008-11-06
Publication date: 2012-06-27
Anticipated expiration: 2028-11-06
Also published as: CN101732577A

Abstract

The invention provides a medicament for treating Meniere's disease, which comprises the following raw materials in proportion: dahurian angelica root, gambir plant, tribulus fruit, gentiana macrophylla, wrinkled gianthyssop herb, pinellia tuber, oriental waterplantain rhizome, atractylodes macrocephala, liquoric root, tall gastrodia tuber and the like. The medicament for treating Meniere's disease is characterized by reasonable compatibility, exact curative effect, good treatment effect and lasting medicinal effect, and effectively solves the problem of relapse of disease after treatment; and the medicament has short treatment time; patients can be treated after taking 10 doses of medicaments, and the relapse rate is low. The medicament not only has the definite curative effect on initial vertigo, but also has remarkable curative effects on relapsing and stuborn diseases, other types of vertigo as well as relapsing diseases that cannot be cured by traditional western medicine method nor by rhizoma gastrodiae pullus cum osse nigro soup in patients.

Description

A kind of medicine of treating Meniere

Technical field

The present invention relates to a kind of medicine of treating Meniere, especially a kind of medicine that is the raw material for treating Meniere with pure Chinese medicine medicine.

Background technology

Meniere is claimed vertigo, auditory vertigo, hydrolabyrinth again, is a kind of commonly encountered diseases, frequently-occurring disease.The appearance of this disease symptoms is to be expanded by hydrops in the internal ear membranous labyrinth, oppresses due to the internal ear end organ.Mainly show as because of ictal dizziness appears in the position change, the sky changes sense, nausea and vomiting dizzyly, can follow tinnitus (being mostly a side) and dysacousis (deafness).Be repeatedly outbreak, whenever flu, be prone to bring out after drunk and tired, bring many inconvenience to patient's work, life, study.Traditional doctor trained in Western medicine is used tranquilizer (stable, phenobarbital, dimenhydrinate etc.), vasodilation (nicotinic acid, 654-2 hydrobromide injection, histamine phosphate, bendazol etc.), dehydrant (acetazolamide, hydrochlorothiazide etc.) and vitamins (B family, VC) treatment the earliest, and human 50% glucose Caledonia caine, vitamin B6 intravenous injection are then arranged.After the treatment, can only temporarily solve symptom, be prone to recurrence.After this, there is human Rhizoma Gastrodiae Gallus Domesticus to treat, the part patient obtained effect preferably, but still can't resolve the recurrence problem.

Summary of the invention

Technical problem to be solved by this invention is a kind of medicine of treating Meniere to be provided, to improve therapeutic effect, the generation that alleviates the recurrence problem.

The present invention is achieved in that a kind of medicine of treating Meniere, and it is made up of the following weight proportion raw material

The Radix Angelicae Dahuricae 10～15 weight portions

Ramulus Uncariae Cum Uncis 10～15 weight portions

Fructus Atriplicis Sibiricae 10～15 weight portions

Radix Gentianae Macrophyllae 10～12 weight portions

Herba Pogostemonis 10～12 weight portions

The Rhizoma Pinelliae 10～12 weight portions

Rhizoma Alismatis 12～15 weight portions

The Rhizoma Atractylodis Macrocephalae 12～15 weight portions

Radix Glycyrrhizae 9～12 weight portions

Rhizoma Gastrodiae 10～15 weight portions

Concha Haliotidis 13～17 weight portions

Pericarpium Citri Reticulatae 9～12 weight portions.

The medicine of this treatment Meniere, compatibility is reasonable, determined curative effect, therapeutic effect is good, and lasting medicine, efficiently solves the problem of treatment back recurrence.Treatment time is short, generally takes 10 doses and gets final product, and relapse rate is low, and therapeutic effect obviously is better than the Rhizoma Gastrodiae Gallus Domesticus Therapeutic Method of the present doctor trained in Western medicine common method of treatment and the traditional Chinese medical science.The present invention's medicine not only has definite curative effect to just sending out a vertigo, and to the obstinate case of outbreak repeatedly, with the patient of traditional doctor trained in Western medicine method treatment back unsatisfactory curative effect, use Rhizoma Gastrodiae Gallus Domesticus soup unsatisfactory curative effect or recurrence good curative effect is arranged also.And the dizzy symptom to other types also has curative effect preferably.

The specific embodiment

Further specify the present invention below.

During use, take by weighing each raw material by proportioning, after the mixing, decocte with water twice, its method is identical with the decocting method of existing water preparation, promptly adds decocting in water earlier one time, pours out medicinal liquid, in medicine, adds decocting in water again one time.The medicinal liquid of twice gained is mixed, sooner or later the secondary sub-service.10 days was 1 course of treatment.Also the fried equipment of available advanced person's Chinese medicine fried good after, process 20 parcel potus, each 1 bag, secondary is taken sooner or later.Add white sugar after also can medicinal liquid being concentrated, process granule, after drying, quantitatively take.

Traditional Chinese medical theory thinks that the pathogeny of Meniere is: stagnation of turbid phlegm in middle-JIAO, excessive rising of liver-YANG.The present invention's medicine merit is at drying dampness to eliminate phlegm, suppressing the hyperactive liver to relieve the wind syndrome, dizzy, the headache of specially disturbing on the dispelling the wind and dampness pathogens expectorant, all cards of vomiting and nausea.Rhizoma Pinelliae drying dampness to eliminate phlegm in the side, stopping nausea and vomiting by lowering the adverse flow of QI, Rhizoma Gastrodiae reduce phlegm endogenous wind stopping and end dizzyly, and two medicines share, for controlling the dizzy key medicine of wind-phlegm, so two to distinguish the flavor of be monarch drug with this.With the Rhizoma Atractylodis Macrocephalae, Radix Gentianae Macrophyllae, Rhizoma Alismatis, Pericarpium Citri Reticulatae is minister, invigorating the spleen to clear away damp pathogen.With the Rhizoma Pinelliae, Rhizoma Gastrodiae compatibility, damp eliminating is reduced phlegm, and it is good to end dizzy end dizzy benefit.Ramulus Uncariae Cum Uncis, Concha Haliotidis, Fructus Atriplicis Sibiricae are calmed down liver-yang, are assistant altogether with Herba Pogostemonis, the Radix Angelicae Dahuricae stomach function regulating of being amusing.Make with Radix Glycyrrhizae with in and transfer the property of medicine.All medicine phases 5, wind-phlegm disappears, and liver-yang is flat, dizzy spontaneous recovery.

Be the clinical effectiveness of the Drug therapy Meniere that shows the present invention, use traditional Western medicine drug, 100 examples to use Rhizoma Gastrodiae Gallus Domesticuss and 100 examples to use the cases of the present invention's Drug therapy Meniere, contrast with 100 examples.Carry out late result simultaneously and follow up a case by regular visits to, add up its relapse rate, carry out the anti-recurrence effect and judge.

The diagnostic criteria of Meniere: 1, just send out or outbreak, the position mobility repeatedly ictal, dizzy commentaries on classics property dizzy.2, follow more nauseating, the vomiting, with or without tinnitus, deafness.3, inspection is visible: horizontal nystagmus or rotatory spontaneous eye are quivered, tuning fork shows perceptive deafness.4, get rid of brain organic pathological changes or arrhythmia caused symptomatic dizzy outbreak.

Curative effect judging standard: recovery from illness, dizzy, tinnitus, deaf three classical symptom complete obiterations.Produce effects, dizzy, tinnitus classical symptom complete obiteration, deafness alleviates.Take a turn for the better, dizzy, tinnitus, deaf three classical symptoms all alleviate.Invalid, dizzy, tinnitus, deaf three classical symptoms all do not have and change or increase the weight of.

Test group: 100 examples, wherein male 50 examples, women 50 examples use the present invention's medicine to treat.Administrated method is with above-mentioned.

Matched group 1:100 example, wherein male 51 examples, women 49 examples, use traditional doctor trained in Western medicine method: stable 5-10mg (oral or injection), 654-2 hydrobromide injection 10-20mg,, VB ₆20mg adds 5% glucose injection 20ml, and vein is slow to be annotated.Once a day, totally 10 days.

Matched group 2:100 example, wherein, male 49 examples, women 51 examples.Get one of Rhizoma Gastrodiae 150g, Gallus Domesticus, after the Gallus Domesticus that lives was fallen to death, the boiled water QUMAO was excavated the five internal organs (cardiopulmonary reservation), and Rhizoma Gastrodiae is filled in the chicken tripe, boiled to eat Carnis Gallus domesticus and drink chicken soup, ate a chicken in two days, had a rest one day, ate second chicken again, had a rest one day again, ate the 3rd chicken.Eat three chickens altogether.

Above-mentioned respectively to organize situation such as case sex, age, the state of an illness suitable basically, and comparability is arranged.

Therapeutic effect sees the following form:

Group	Recovery from illness (routine number)	Produce effects (routine number)	Take a turn for the better (routine number)	Invalid (routine number)
					Matched group 1	60	30	10	0
Matched group 2	80	12	8	0
					Test group	96	4	0	0

Can find out that from last table the therapeutic effect of the present invention's medicine obviously is superior to each matched group.

After finishing back 3 months, half a year, 1 year, 3 years, 5 years, 10 years the course of treatment, pay a return visit respectively, judge relapse rate, data are percent %.The result sees the following form:

Group	Relapse rate after 3 months	Relapse rate after half a year	Relapse rate after 1 year	Relapse rate after 3 years	Relapse rate after 5 years	Relapse rate after 10 years
							Matched group 1	60	30	10	0	0	0
Matched group 2	57	25	18	0	0	0
							Test group	0	4	2	0	0	0

[0033]Show that through last table 3 months of matched group 1, the relapse rate of half a year are the highest, matched group 2 is lower slightly, and test group is minimum.The all recurrences in 1 year of two matched groups.Total relapse rate is merely 6% in the test group 1 year, explains that test group shows highly significant aspect anti-recurrence.

Embodiment 1

Take by weighing Radix Angelicae Dahuricae 10g, Ramulus Uncariae Cum Uncis 15g, Fructus Atriplicis Sibiricae 10g, Radix Gentianae Macrophyllae 12g, Herba Pogostemonis 10g, Rhizoma Pinelliae 12g, Rhizoma Alismatis 12g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 9g, Rhizoma Gastrodiae 15g, Concha Haliotidis 13g, Pericarpium Citri Reticulatae 12g.After the mixing, decocte with water twice, its method is identical with the decocting method of existing water preparation, promptly adds decocting in water earlier one time, pours out medicinal liquid, in medicine, adds decocting in water again one time.The medicinal liquid of twice gained is mixed, sooner or later the secondary sub-service.

Embodiment 2

Take by weighing Radix Angelicae Dahuricae 15g, Ramulus Uncariae Cum Uncis 10g, Fructus Atriplicis Sibiricae 15g, Radix Gentianae Macrophyllae 12g, Herba Pogostemonis 12g, Rhizoma Pinelliae 10g, Rhizoma Alismatis 15g, Rhizoma Atractylodis Macrocephalae 12g, Radix Glycyrrhizae 12g, Rhizoma Gastrodiae 10g, Concha Haliotidis 17g, Pericarpium Citri Reticulatae 9g.After the mixing, decocte with water twice, its method is identical with the decocting method of existing water preparation, promptly adds decocting in water earlier one time, pours out medicinal liquid, in medicine, adds decocting in water again one time.The medicinal liquid of twice gained is mixed, sooner or later the secondary sub-service.

Embodiment 3

Take by weighing Radix Angelicae Dahuricae 10g, Ramulus Uncariae Cum Uncis 10g, Fructus Atriplicis Sibiricae 15g, Radix Gentianae Macrophyllae 10g, Herba Pogostemonis 12g, Rhizoma Pinelliae 10g, Rhizoma Alismatis 12g, Rhizoma Atractylodis Macrocephalae 12g, Radix Glycyrrhizae 9g, Rhizoma Gastrodiae 10g, Concha Haliotidis 13g, Pericarpium Citri Reticulatae 9g.After the mixing, decocte with water twice, its method is identical with the decocting method of existing water preparation, promptly adds decocting in water earlier one time, pours out medicinal liquid, in medicine, adds decocting in water again one time.The medicinal liquid of twice gained is mixed, sooner or later the secondary sub-service.

Embodiment 4

Take by weighing Radix Angelicae Dahuricae 15g, Ramulus Uncariae Cum Uncis 15g, Fructus Atriplicis Sibiricae 15g, Radix Gentianae Macrophyllae 12g, Herba Pogostemonis 12g, Rhizoma Pinelliae 12g, Rhizoma Alismatis 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 12g, Rhizoma Gastrodiae 15g, Concha Haliotidis 17g, Pericarpium Citri Reticulatae 12g.After the mixing, decocte with water twice, its method is identical with the decocting method of existing water preparation, promptly adds decocting in water earlier one time, pours out medicinal liquid, in medicine, adds decocting in water again one time.The medicinal liquid of twice gained is mixed, sooner or later the secondary sub-service.

Claims

1. a medicine of treating Meniere is characterized in that, it is made up of the following weight proportion raw material