CN103687483A - 用于呼吸递送两种或多种活性剂的组合物、方法和系统 - Google Patents
用于呼吸递送两种或多种活性剂的组合物、方法和系统 Download PDFInfo
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- CN103687483A CN103687483A CN201180072341.4A CN201180072341A CN103687483A CN 103687483 A CN103687483 A CN 103687483A CN 201180072341 A CN201180072341 A CN 201180072341A CN 103687483 A CN103687483 A CN 103687483A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
- A61L9/02—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air by heating or combustion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510242737.9A CN105106200A (zh) | 2011-05-17 | 2011-05-17 | 用于呼吸递送两种或多种活性剂的组合物、方法和系统 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/036868 WO2012158166A1 (en) | 2011-05-17 | 2011-05-17 | Compositions, methods & systems for respiratory delivery of two or more active agents |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510242737.9A Division CN105106200A (zh) | 2011-05-17 | 2011-05-17 | 用于呼吸递送两种或多种活性剂的组合物、方法和系统 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN103687483A true CN103687483A (zh) | 2014-03-26 |
Family
ID=47177229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201180072341.4A Pending CN103687483A (zh) | 2011-05-17 | 2011-05-17 | 用于呼吸递送两种或多种活性剂的组合物、方法和系统 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP2709447A4 (pt) |
JP (1) | JP2014518871A (pt) |
KR (1) | KR20140032404A (pt) |
CN (1) | CN103687483A (pt) |
AU (1) | AU2011368334A1 (pt) |
BR (1) | BR112013029507A2 (pt) |
CA (1) | CA2835927A1 (pt) |
EA (1) | EA201490991A1 (pt) |
IL (1) | IL229260A0 (pt) |
MX (1) | MX2013013440A (pt) |
RU (1) | RU2013155903A (pt) |
SG (1) | SG194896A1 (pt) |
WO (1) | WO2012158166A1 (pt) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105125542A (zh) * | 2015-08-23 | 2015-12-09 | 杭州紫金医药科技有限公司 | 含噻托溴铵和福莫特罗的药物组合物及其用途和制剂 |
CN106880637A (zh) * | 2015-12-15 | 2017-06-23 | 天津金耀集团有限公司 | 一种环索奈德福莫特罗噻托溴铵复方干粉吸入剂组合物 |
CN106880636A (zh) * | 2015-12-15 | 2017-06-23 | 天津金耀集团有限公司 | 一种环索奈德单方和复方干粉吸入剂组合物 |
CN106943350A (zh) * | 2017-03-14 | 2017-07-14 | 上海现代药物制剂工程研究中心有限公司 | 含毒蕈碱受体拮抗剂和β2受体激动剂的气雾剂及制备方法 |
CN107666903A (zh) * | 2015-05-01 | 2018-02-06 | 得克萨斯州大学系统董事会 | 多药脆性基质组合物 |
CN111467498A (zh) * | 2020-05-14 | 2020-07-31 | 王兆霖 | 药物组合物制剂 |
WO2022148418A1 (zh) * | 2021-01-08 | 2022-07-14 | 江苏恒瑞医药股份有限公司 | 可通过定量吸入器递送的药物组合物 |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
ES2774391T3 (es) | 2009-05-29 | 2020-07-20 | Pearl Therapeutics Inc | Composiciones, métodos y sistemas para la administración respiratoria de dos o más agentes activos |
BR112015018121A2 (pt) | 2013-01-31 | 2017-07-18 | Prosonix Ltd | composição para terapia por inalação, composição farmacêutica, inalador de pó seco, inalador pressurizado dosimetrado ou inalador nasal ativado por respiração, método de tratar uma doença ou distúrbio respiratório ou uma doença ou distúrbio pulmonar em um paciente, e, método de preparar composições ou inaladores |
RU2696582C2 (ru) | 2013-03-15 | 2019-08-05 | Перл Терапьютикс, Инк. | Способы и системы кондиционирования дисперсных кристаллических материалов |
MX2015016058A (es) * | 2013-05-22 | 2016-12-20 | Pearl Therapeutics Inc | Composiciones, metodos y sistemas para el suministro por via respiratoria de tres o mas agentes activos. |
SG11201605311UA (en) | 2013-12-30 | 2016-07-28 | Chiesi Farma Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
ME03076B (me) * | 2013-12-30 | 2019-01-20 | Chiesi Farm Spa | Stabilna pod priтiskom kompozicija aerosolnog rastvora glikopironijum bromida i kombinacije formoterola |
TN2017000077A1 (en) | 2014-09-09 | 2018-07-04 | Vectura Ltd | Formulation comprising glycopyrrolate, method and apparatus |
WO2016170518A1 (en) | 2015-04-24 | 2016-10-27 | Glenmark Specialty S.A. | Pharmaceutical compositions comprising arformoterol and glycopyrronium |
WO2020100040A1 (en) * | 2018-11-12 | 2020-05-22 | 3M Innovative Properties Company | Umeclidinium and vilanterol formulation and inhaler |
WO2021071967A1 (en) * | 2019-10-09 | 2021-04-15 | Island Breeze Systems Ca, Llc | Compositions for pulmonary delivery of cannabinoids and associated methods and systems |
IL309888A (en) * | 2021-07-09 | 2024-03-01 | Astrazeneca Pharmaceuticals Lp | Aerosol drug delivery compounds, methods and systems |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010138862A2 (en) * | 2009-05-29 | 2010-12-02 | Pearl Therapeutics, Inc. | Compositions for respiratory delivery of active agents and associated methods and systems |
US20120039952A1 (en) * | 2009-05-29 | 2012-02-16 | Pearl Therapeutics, Inc. | Compositions, methods & systems for respiratory delivery of two or more active agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2304819C (en) * | 1997-09-29 | 2008-04-08 | Inhale Therapeutic Systems, Inc. | Perforated microparticles and methods of use |
US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
GB9903759D0 (en) * | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
SE527190C2 (sv) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Inhalatoranordning samt kombinerade doser av en beta2-agonist, ett antikolinergiskt medel och ett antiinflammatorisk steroid |
DE602005007708D1 (de) * | 2004-02-06 | 2008-08-07 | Meda Pharma Gmbh & Co Kg | Neue kombination von anticholinergen und beta mimetika zur behanldung von atemwegserkrankungen |
-
2011
- 2011-05-17 EP EP11865780.8A patent/EP2709447A4/en not_active Withdrawn
- 2011-05-17 SG SG2013083431A patent/SG194896A1/en unknown
- 2011-05-17 JP JP2014511329A patent/JP2014518871A/ja active Pending
- 2011-05-17 WO PCT/US2011/036868 patent/WO2012158166A1/en active Application Filing
- 2011-05-17 CN CN201180072341.4A patent/CN103687483A/zh active Pending
- 2011-05-17 AU AU2011368334A patent/AU2011368334A1/en not_active Abandoned
- 2011-05-17 MX MX2013013440A patent/MX2013013440A/es unknown
- 2011-05-17 RU RU2013155903/15A patent/RU2013155903A/ru not_active Application Discontinuation
- 2011-05-17 BR BR112013029507A patent/BR112013029507A2/pt not_active IP Right Cessation
- 2011-05-17 CA CA2835927A patent/CA2835927A1/en not_active Abandoned
- 2011-05-17 KR KR1020137030446A patent/KR20140032404A/ko not_active Application Discontinuation
- 2011-05-17 EA EA201490991A patent/EA201490991A1/ru unknown
-
2013
- 2013-11-05 IL IL229260A patent/IL229260A0/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010138862A2 (en) * | 2009-05-29 | 2010-12-02 | Pearl Therapeutics, Inc. | Compositions for respiratory delivery of active agents and associated methods and systems |
WO2010138884A2 (en) * | 2009-05-29 | 2010-12-02 | Pearl Therapeutics, Inc. | Compositions, methods & systems for respiratory delivery of two or more active agents |
US20120039952A1 (en) * | 2009-05-29 | 2012-02-16 | Pearl Therapeutics, Inc. | Compositions, methods & systems for respiratory delivery of two or more active agents |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107666903A (zh) * | 2015-05-01 | 2018-02-06 | 得克萨斯州大学系统董事会 | 多药脆性基质组合物 |
CN107666903B (zh) * | 2015-05-01 | 2021-08-20 | 得克萨斯州大学系统董事会 | 多药脆性基质组合物 |
CN105125542A (zh) * | 2015-08-23 | 2015-12-09 | 杭州紫金医药科技有限公司 | 含噻托溴铵和福莫特罗的药物组合物及其用途和制剂 |
CN106880637A (zh) * | 2015-12-15 | 2017-06-23 | 天津金耀集团有限公司 | 一种环索奈德福莫特罗噻托溴铵复方干粉吸入剂组合物 |
CN106880636A (zh) * | 2015-12-15 | 2017-06-23 | 天津金耀集团有限公司 | 一种环索奈德单方和复方干粉吸入剂组合物 |
CN106943350A (zh) * | 2017-03-14 | 2017-07-14 | 上海现代药物制剂工程研究中心有限公司 | 含毒蕈碱受体拮抗剂和β2受体激动剂的气雾剂及制备方法 |
CN111467498A (zh) * | 2020-05-14 | 2020-07-31 | 王兆霖 | 药物组合物制剂 |
WO2022148418A1 (zh) * | 2021-01-08 | 2022-07-14 | 江苏恒瑞医药股份有限公司 | 可通过定量吸入器递送的药物组合物 |
Also Published As
Publication number | Publication date |
---|---|
WO2012158166A1 (en) | 2012-11-22 |
KR20140032404A (ko) | 2014-03-14 |
JP2014518871A (ja) | 2014-08-07 |
MX2013013440A (es) | 2014-06-05 |
RU2013155903A (ru) | 2015-06-27 |
IL229260A0 (en) | 2014-01-30 |
EP2709447A4 (en) | 2014-10-22 |
AU2011368334A1 (en) | 2013-11-21 |
CA2835927A1 (en) | 2012-11-22 |
BR112013029507A2 (pt) | 2019-09-24 |
EP2709447A1 (en) | 2014-03-26 |
EA201490991A1 (ru) | 2014-09-30 |
SG194896A1 (en) | 2013-12-30 |
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AU2018282272B2 (en) | Compositions, methods & systems for respiratory delivery of two or more active agents | |
AU2019203814A1 (en) | Compositions for respiratory delivery of active agents and associated methods and systems | |
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Application publication date: 20140326 |