CN103656664A - Pig self feeding type drug carrier and preparation method thereof - Google Patents
Pig self feeding type drug carrier and preparation method thereof Download PDFInfo
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- CN103656664A CN103656664A CN201310719446.5A CN201310719446A CN103656664A CN 103656664 A CN103656664 A CN 103656664A CN 201310719446 A CN201310719446 A CN 201310719446A CN 103656664 A CN103656664 A CN 103656664A
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Abstract
The invention relates to a pig self feeding type drug carrier and a preparation method thereof. The drug carrier comprises the following components by weight percent: 12%-25% of hawthorns, 3%-9% of bee honey, 0.4%-8% of carrageenan, 0.8%-1.2% of calcium hydrogen phosphate, 0.01%-2% of compound vitamins, 0.01%-0.5% of compound mineral substances, 0.02%-0.05% of potassium sorbate, and 58%-82% of moisture. The drug carrier is suitable for direct feeding, is used for treating and preventing the common clinical diseases of pigs, and achieves the double effects of treating and preventing the diseases and enhancing physique, meanwhile, the drug carrier has the advantages of good palatability, convenience in use, and the like, and the pigs eat the drug carrier independently. The problems of time and effort consumption during operation, animal stress response, pain and the like caused by feeding and injecting the drugs, are solved. In addition, the drug carrier has the advantages that the production technology is simple, the source of raw materials is wide, the production cost is low, and the drug carrier is suitable for large scale production.
Description
Technical field
The invention belongs to animal medicine technical field, relate to a kind of novel pig independently search for food formula and the preparation method of type pharmaceutical carrier.
Background technology
Along with the developing rapidly of Animal Husbandry in China, China's pig-breeding quantity has reached No. 1 in the world in recent years, accounts for the world the over half of total amount of raising pigs, China in recent years the live pig amount of delivering for sale greatly about 600,000,000/year.Along with increasing of pig cultivation quantity, the quantity of ill pig also increases thereupon, the common disease of pig be infectious disease (virus, antibacterial and mycoplasma disease), parasitic disease, Medicine and Surgery and obstetrics' disease etc., wherein the sickness rate of infectious disease and case fatality rate are all very high, all can occur throughout the year, the health of serious threat pig, brings great economic loss to pig industry.
The administering mode of pig clinical disease mainly contains injection, tablet, granule and powder, liquor etc. at present, but equal Shortcomings part, as the using method of injection mostly is intramuscular injection, during injection, pain perception makes pig produce resentment and stress, may cause unnecessary injury to people, in addition, injection needs professional and technical personnel in person to operate, there is certain limitation, also may have pathophorous risk; Tablet mostly is bitter in the mouth, and pig is reluctant initiatively to absorb, and often can tell medicine, is unfavorable for feeding; Granule and powder mostly are granule and powder, need evenly admix feedstuff or sneak in drinking-water and use, and specific aim is not strong; And liquor generally need to be filled with one by one and fed, use inconvenient.
Therefore, control pig clinical disease should further be found new drug formulation, can initiatively ingest, and good palatability, in the mode of feeding, prevent and treat the common clinical disease of pig, prevention effect is obvious.
The present invention is according to the nutritional need of pig, developed the boar type pharmaceutical carrier of independently searching for food, this carrier comprises the essential nutrient substance of pig as calcium hydrogen phosphate, vitamin and mineral etc., special Fructus Crataegi and the Mel of adding, the gastrointestinal function of facilitating digestion and absorption, conditioning pig, can be used as daily ration for pig provides full nutrition, can also add medicine, to realize the object of prevention and treatment disease.This carrier have can independently search for food, palatability is strong, the advantage such as easy to use, for prevention and the treatment of pig clinical disease provides a new approach.
Summary of the invention
The object of the invention is to develop the boar type pharmaceutical carrier of independently searching for food, and further improve the preparation method of this pharmaceutical carrier, mode by it by feeding is applied to the control of the common clinical disease of pig, reach disease preventing and treating and constitutional double effects, significantly reduce disease incident and the case fatality rate of pig, improve cure rate, overcome the deficiency of existing clinical administration mode.
The pig of the present invention type pharmaceutical carrier of independently searching for food, its mass percent is composed as follows:
Except above-mentioned underlying carrier component, can also add one or more in following component to obtain the reinforced pig type pharmaceutical carrier of independently searching for food, each component and shared mass percent thereof are:
Fructus Crataegi in the present invention's formula has out the features such as spleen stomach invigorating, appetite stimulator, shortization that help digestion.Mel in the present invention formula can be nursed one's health the gastrointestinal function of pig, reduces the prevalence of piglets, improves its survival rate, and in can improving, diseases prevention and the resistance against diseases of large pig.
Independently the search for food preparation method of type pharmaceutical carrier of pig disclosed by the invention is: the carrageenan of the Mel of the Fructus Crataegi of mass percent 12-25%, 3-9%, 0.4-8% is added in container, adding water stirs, heated and boiled to glue dissolves completely, remove impurity and foam wherein, obtain glutinous sliding mixture, be filled in the packaging cup of having sterilized, seal immediately and carry out pasteurization, the cooling rear acquisition pig type pharmaceutical carrier of independently searching for food.
Independently the search for food preparation method of type pharmaceutical carrier of reinforced pig disclosed by the invention is: by the Fructus Crataegi of mass percent 12-25%, the Mel of 3-9%, the carrageenan of 0.4-8% adds in container, adding water stirs, heated and boiled to glue dissolves completely, remove impurity and foam wherein, then add calcium hydrogen phosphate, compound vitamin, wherein one or more of composite mineral matter and potassium sorbate, mix, make glutinous sliding mixture, be filled in the packaging cup of having sterilized, seal immediately and carry out pasteurization, the cooling rear acquisition pig type pharmaceutical carrier of independently searching for food.
The invention has the beneficial effects as follows: the Fructus Crataegi that (1) these goods add and Mel have the advantages such as gastrointestinal function of facilitating digestion, appetite stimulator and conditioning pig.(2) medicine can be coated in pharmaceutical carrier, cover bitterness, not affect feed intake, pig can independently search for food, convenience and high-efficiency.(3) preparation is simple, cost is low, has no side effect, and raw material sources are extensive, easy to use, is easy to promote.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment:
By 150g Fructus Crataegi, 8g carrageenan and 50g Mel with add 773.6g water post-heating and boil, add 12g calcium hydrogen phosphate, 2g compound vitamin, 1g composite mineral matter to allocate, obtain pharmaceutical carrier; Again 3.2g gentamycin sulfate is added in pharmaceutical carrier, after adding 0.2g potassium sorbate, mix, make the 1000g pig type pharmaceutical carrier of independently searching for food, then pour in 20 50g fractional pack cups of having sterilized, seal immediately and carry out pasteurization, cooling rear room temperature preservation.
Clinical trial:
(1) product stability test
The pharmaceutical carrier room temperature containing 0.16% gentamycin sulfate preparing is placed, by the observations of 12 months and detection, result shows, pig independently searches for food type pharmaceutical carrier color, abnormal smells from the patient, taste all without significant change, the relative amount of gentamycin sulfate only declines 7%, and pharmaceutically active storage rate is still up to 93%.Therefore, the shelf-life of pharmaceutical carrier of the present invention is not less than 1 year.
(2) palatability testing
20, pig farm, Daliang City pig is divided into two groups at random, every group 10, experimental group feeding is containing the pharmaceutical carrier of 0.16% gentamycin sulfate, and matched group feeding is the pharmaceutical carrier of sulfur acid gentamycin not, one day 1-2 time, feeding 2 days, result shows matched group and all eats up in experimental group 1-2 minute, shows that this pharmaceutical carrier is coated with successfully, covered bitterness, do not affect feed intake, good palatability, applicable pig independently searches for food.
(3) therapeutic effect test
From pig farm, Daliang City, obtain 60 piglets that suffer from diarrhoea, be divided at random A, B, tri-groups of C, every group 20, A group feeding is the common drug carrier of sulfur acid gentamycin not, B group feeding is containing the pharmaceutical carrier of 0.16% gentamycin sulfate, every pharmaceutical carrier 50g, every 1 of feeding (too small the reducing by half of body weight), C organizes intramuscular injection gentamycin sulfate (2ml:8 million international units), every too small injection 1.5ml of injection 1.5-2ml(body weight), every day 1 time, be used in conjunction 3 days, in equivalent environment, raise, observe therapeutic effect every day, after 3 days, carry out all-round statistics, result is as shown in the table:
Independently the search for food therapeutic effect of type pharmaceutical carrier of table 1 pig
Result demonstration, the feeding not cure rate of the common drug vehicle Control group of sulfur acid gentamycin is 10%, total effective rate reaches 15%; Feeding is containing the cure rate of the pharmaceutical carrier experimental group of 0.16% gentamycin sulfate up to 85%, and total effective rate reaches 90%; The cure rate of intramuscular injection gentamycin sulfate matched group is 80%, and total effective rate reaches 85%, and experimental group is more effective than matched group, illustrates that therapeutic effect of the present invention is better, and cure rate is high.
In the above-described embodiment, invention is described for the implementation that may occur, and describes the present invention by illustrative examples, and the example of enumerating can't limit the protection domain of the claims in the present invention.
Claims (4)
1. the boar type pharmaceutical carrier of independently searching for food, is characterized in that, this pig type pharmaceutical carrier of independently searching for food comprises 12-25% Fructus Crataegi, 3-9% Mel, 0.4-8% carrageenan and 58-82% moisture, and above each component is prepared by mass percentage.
2. a boar as claimed in claim 1 type pharmaceutical carrier of independently searching for food, is characterized in that, the described pig type pharmaceutical carrier of independently searching for food can also comprise one or more in calcium hydrogen phosphate, compound vitamin, composite mineral matter and potassium sorbate.Each component accounts for carrier gross mass percentage ratio:
3. a boar as claimed in claim 1 preparation method of type pharmaceutical carrier of independently searching for food, its characterization step is as follows:
The carrageenan of the Mel of the Fructus Crataegi of mass percent 12-25%, 3-9%, 0.4-8% is added in container, adding water stirs, heated and boiled to glue dissolves completely, remove impurity and foam wherein, obtain glutinous sliding mixture, be filled in the packaging cup of having sterilized, seal immediately and carry out pasteurization, the cooling rear acquisition pig type pharmaceutical carrier of independently searching for food.
4. a boar as claimed in claim 2 preparation method of type pharmaceutical carrier of independently searching for food, its characterization step is as follows:
The carrageenan of the Mel of the Fructus Crataegi of mass percent 12-25%, 3-9%, 0.4-8% is added in container, adding water stirs, heated and boiled to glue dissolves completely, remove impurity and foam wherein, then add one or more in calcium hydrogen phosphate, compound vitamin, composite mineral matter and potassium sorbate, mix, make glutinous sliding mixture, be filled in the packaging cup of having sterilized, seal immediately and carry out pasteurization, the cooling rear acquisition pig type pharmaceutical carrier of independently searching for food.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310719446.5A CN103656664B (en) | 2013-12-20 | 2013-12-20 | A kind of pig self feeding type pharmaceutical carrier and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310719446.5A CN103656664B (en) | 2013-12-20 | 2013-12-20 | A kind of pig self feeding type pharmaceutical carrier and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
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| CN103656664A true CN103656664A (en) | 2014-03-26 |
| CN103656664B CN103656664B (en) | 2016-08-31 |
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| CN201310719446.5A Active CN103656664B (en) | 2013-12-20 | 2013-12-20 | A kind of pig self feeding type pharmaceutical carrier and preparation method thereof |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1824127A (en) * | 2005-01-14 | 2006-08-30 | 贵阳云岩西创药物科技开发有限公司 | Spleen fortifying appetite increasing gel preparation for child and its preparation method |
| CN1826948A (en) * | 2006-04-14 | 2006-09-06 | 东莞兴业生物科技有限公司 | Preparation method of compound feedstuff for porket and compound feedstuff prepared therefrom |
| CN101085193A (en) * | 2006-06-09 | 2007-12-12 | 由春娜 | Method for preparing children indigestion-relieving gel |
| CN102669518A (en) * | 2012-06-20 | 2012-09-19 | 赵立林 | Jelly with function of invigorating stomach and promoting digestion |
| CN102823787A (en) * | 2012-07-31 | 2012-12-19 | 安徽省林锦记食品工业有限公司 | Gastrointestinal regulation jelly and method for making same |
-
2013
- 2013-12-20 CN CN201310719446.5A patent/CN103656664B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1824127A (en) * | 2005-01-14 | 2006-08-30 | 贵阳云岩西创药物科技开发有限公司 | Spleen fortifying appetite increasing gel preparation for child and its preparation method |
| CN1826948A (en) * | 2006-04-14 | 2006-09-06 | 东莞兴业生物科技有限公司 | Preparation method of compound feedstuff for porket and compound feedstuff prepared therefrom |
| CN101085193A (en) * | 2006-06-09 | 2007-12-12 | 由春娜 | Method for preparing children indigestion-relieving gel |
| CN102669518A (en) * | 2012-06-20 | 2012-09-19 | 赵立林 | Jelly with function of invigorating stomach and promoting digestion |
| CN102823787A (en) * | 2012-07-31 | 2012-12-19 | 安徽省林锦记食品工业有限公司 | Gastrointestinal regulation jelly and method for making same |
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| CN103656664B (en) | 2016-08-31 |
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