CN103656106A

CN103656106A - Medicine for treating infantile rectocele and preparation method thereof

Info

Publication number: CN103656106A
Application number: CN201310678338.8A
Authority: CN
Inventors: 沈玉山
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-14
Filing date: 2013-12-14
Publication date: 2014-03-26

Abstract

The invention discloses a medicine for treating infantile rectocele and a preparation method thereof. The medicine is mainly prepared from the following components at a certain weight ratio: earthworm, pericarpium granati, tiger-bone and iron concentrate. The medicine has the effects of warming middle-Jiao and dredging collaterals and tonifying qi and preventing exhaustion and is fast in effectiveness in treatment of infantile rectocele and good in curative effect, and the infantile rectocele does not reoccur.

Description

A kind of medicine for the treatment of pediatric proctoptosis and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of pediatric proctoptosis and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Pediatric proctoptosis refers to children anal canal rectum, and even part transposition of colon is de-outside declining.Proctoptosis initially only occurs when putting forth one's strength defecation, after an action of the bowels can automatic retraction.With hands, help to send back possibly afterwards, while sometimes not defecating while crying and screaming (as)) also can occur.As it not sent back to for a long time, can there is edema, oozing of blood, ulcer and the falling inflation that causes, pain, tenesmus, the blood mucus of suppurating.Mostly occur at 4 years old with interior children's.Because Western medicine cannot effectively be treated pediatric proctoptosis, so there is great demand to the Chinese medicine of rapid, effective treatment pediatric proctoptosis in people, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment pediatric proctoptosis, thereby has completed the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment pediatric proctoptosis.

Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.

Medicine of the present invention is to select Lumbricus, Pericarpium Granati, Os Tigris, Haematite, Folium Allii tuberosi medicine to combine preparation, makes each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat pediatric proctoptosis.Wherein select Lumbricus to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, there is heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control height fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor are bitter, cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, and adult's blood pressure is higher, dizzy, dizzy, married woman's eclampsia.Select Pericarpium Granati to be because its nature and flavor are sour and astringent, temperature, poisonous, enter large intestine, kidney channel, there is astringing intestine to stop diarrhea, hemostasis, the function of anthelmintic, controls chronic diarrhea, and chronic dysentery is had blood in stool, proctoptosis, spermatorrhea, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation, scabies.Select Os Tigris to be because its nature and flavor are pungent, temperature, enters liver, kidney channel, chases after wind analgesic therapy, strong bone, relieving convulsion function, controls severe and migratory arthralgia pain, spasm of the limbs, waist foot not with, palpitation with fear epilepsy, hemorrhoid complicated by anal fistula proctoptosis.Select Haematite to be because its nature and flavor are arduous, flat, there is tranquillizing and allaying excitement, the function of subduing swelling and detoxicating, Zhi Jing Epilepsy cardiopalmus, furunculosis, swelling of the vulva, proctoptosis.Select Folium Allii tuberosi to be because its nature and flavor are pungent, temperature, enters liver, stomach, kidney channel, has warming middle-JIAO, circulation of qi promoting, and loose blood, the function of removing toxic substances, controls the thoracic obstruction, chokes every, regurgitation, and haematemesis, epistaxis, hematuria, dysentery, quench one's thirst, anal fistula, proctoptosis, injury from falling down, worm, scorpion sting.

The specific embodiment

The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight

Lumbricus 8-15 gram of Pericarpium Granati 6-12 gram of Os Tigris 4-8 gram

Haematite 10-18 gram of Folium Allii tuberosi 80-150 gram

Be preferably

6 grams of 8 grams of Os Tigriss of 10 grams of Pericarpium Granatis of Lumbricus

100 grams, 12 grams of Folium Allii tuberosi of Haematite

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Lumbricus: choose decontamination, water rinses, and pulls out in time;

2, Pericarpium Granati: choose decontamination, remove residual interior flesh and son, clean stripping and slicing;

3, Os Tigris: remove muscles, clean, dry in the shade, face the used time and smash to pieces;

4, Haematite: choose decontamination, porphyrize;

5, Folium Allii tuberosi: get fresh Folium Allii tuberosi, choose decontamination, clean.

Two, preparation

1, by the Lumbricus of described weight, Pericarpium Granati respectively watt on dry;

2, the Os Tigris of described Lumbricus of drying, Pericarpium Granati and described weight is ground to the powder altogether;

3, the Haematite of described weight is added in ground Lumbricus, Pericarpium Granati, Os Tigris smalls, mix thoroughly;

4, the Folium Allii tuberosi of described weight is mashed into mud shape;

5, the described Lumbricus mixing, Pericarpium Granati, Os Tigris, Haematite smalls are added in Folium Allii tuberosi mud, mix thoroughly, be the ointment described in the present invention.

Medicine of the present invention has warming middle-JIAO dredging collateral, and the function of supplementing QI to prevent collapse is used for the treatment of pediatric proctoptosis instant effect, good effect.

By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, first exposes skin by rabbit abdominal part hair removing, then the ointment mixing up is spread upon to rabbit abdominal part baring skin place, then with gauze, twine and tie up, every day, coating was 2 times, and coating is 5 days continuously, observed administration reaction every day, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's totally 100 examples for medical treatment.

2, diagnostic criteria

The cardinal symptom of anal orifice and rectal intestine prolapsus is for deviating from, the initial stage during defecation mucous membrane of rectum deviate from, self-resetting after an action of the bowels; Along with the progress of the state of an illness, passive protective physical fitness weakens gradually, with the passing of time loses and controls, and rectum holostrome or part sigmoid colon are outstanding, even coughs, heavy burden, walking along the street, also can deviate from while squatting down, and be difficult for resetting, and after need to returning or lie up with hand push, can reset.Generally, without bleeding, while being hard and dry once in a while, scratch mucosa is bled, and blood stool or toilet paper have blood while wiping, but amount of bleeding is less.Part patient is due to Sphincter ani chalasia, shrinks unablely, often has mucus to overflow in anus, so that has moist feeling.Or deviate from because of it, do not reset in time, mucous membrane of rectum hyperemia, edema or erosion, mucus stimulates anal skin and causes scratching where it itches.

3, Therapeutic Method

Select above-mentioned ointment, to patient, be applied to affected part, every day 2 times, sooner or later each coating is 1 time, and coating 10 days is a course for the treatment of, continuously 2 courses for the treatment of of coating.

4, efficacy assessment standard

Effective: the recovery from illness of pediatric proctoptosis symptom, recovers normal.

Take a turn for the better: pediatric proctoptosis symptom alleviates, progressively take a turn for the better.

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

Figure 2013106783388100002DEST_PATH_IMAGE001

In above-mentioned treatment, by Drug therapy pediatric proctoptosis patient of the present invention 100 examples, effective 87 examples of result, obvious effective rate is 87%, 5 examples that take a turn for the better, and improvement rate is 5%, invalid 8 examples, total effective rate is 92%.

Claims

1. a medicine for the treatment of pediatric proctoptosis, is characterized in that: it is to be made by the crude drug in following weight range:

Lumbricus 8-15 gram of Pericarpium Granati 6-12 gram of Os Tigris 4-8 gram

Haematite 10-18 gram of Folium Allii tuberosi 80-150 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

100 grams, 12 grams of Folium Allii tuberosi of Haematite.

3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) Lumbricus: choose decontamination, water rinses, and pulls out in time;

(2) Pericarpium Granati: choose decontamination, remove residual interior flesh and son, clean stripping and slicing;

(3) Os Tigris: remove muscles, clean, dry in the shade, face the used time and smash to pieces;

(4) Haematite: choose decontamination, porphyrize;

(5) Folium Allii tuberosi: get fresh Folium Allii tuberosi, choose decontamination, clean;

(2) preparation

(1) by the Lumbricus of described weight, Pericarpium Granati respectively watt on dry;

(2) Os Tigris of described Lumbricus of drying, Pericarpium Granati and described weight is ground to the powder altogether;

(3) Haematite of described weight is added in ground Lumbricus, Pericarpium Granati, Os Tigris smalls, mix thoroughly;

(4) Folium Allii tuberosi of described weight is mashed into mud shape;

(5) the described Lumbricus mixing, Pericarpium Granati, Os Tigris, Haematite smalls are added in Folium Allii tuberosi mud, mix thoroughly, be the ointment described in the present invention.