CN103651587A - Special biological antibacterial liquid for toothbrush - Google Patents

Abstract

The invention relates to special biological antibacterial liquid for a toothbrush. The special biological antibacterial liquid has main effects that the toothbrush bristle body and an oral cavity can be disinfected after a toothbrush bristle body is soaked in the antibacterial liquid, and contained substances can be used for supplementing calcium needed by teeth to protect the health of the teeth. The special biological antibacterial liquid for the toothbrush has the advantages that (1) the product has an obvious antibacterial effect; an experiment shows that the antibacterial rates of the product to bacteria and fungi attached in the toothbrush bristle body can reach 99.99%; (2) the product has good degradation and removing effects on food residues remained between tooth cracks; (3) biological type components have no injuries on the toothbrush bristle body and the oral cavity so that the special biological antibacterial liquid can effectively prevent oral diseases and have no irritation on oral mucosa; (4) the special biological antibacterial liquid is convenient to carry and can be used for resisting bacteria and disinfecting the toothbrush when people go out and travel; (5) a concentration type formula is adopted, the use content is low, the process is simple and the cost is low.

Description

Toothbrush special bio antimicrobial fluid

technical fieldthe present invention relates to a kind of toothbrush special bio antimicrobial fluid; to be protein resolvase, Tea Polyphenols, glucomannan, shitosan, alginase, bacitracin, Rhein form through special process is composite the effective ingredient of formula; primary effect is bristles body to be put into this antimicrobial fluid soak; bristles body and oral cavity are carried out disinfection; and it is required calcareous that contained material can supplement tooth, protects the health of one's teeth.Along with the raising of people's personal hygiene, toothbrush has been object indispensable in daily life, and it can cleaning teeth, kill the germ in oral cavity, creates the environment of a colony balance to tooth.But toothbrush, after after brushing, can carry out the bacterium in oral cavity, and toothbrush majority is in moist, dark, nonventilated environment, will aggravate like this growing of bacterium on toothbrush, while again brushing teeth, bacterium will enter oral cavity with toothbrush, oral cavity is polluted to harm dental health.Therefore, the sterilization of toothbrush is just extremely important.Existing toothbrush sanitizing mode has multiple on the market, a kind of easy to carry be to utilize ultraviolet ray to kill the bacterium on toothbrush, although like this toothbrush bacterium is had to good killing action, device is too complicated, volume large, need to battery be installed and ultraviolet ray has injury all can bring inconvenience to use to human body to device; Liquid disinfection liquid easy to carry majority is chemical composition, and strong oxidizing property has stimulation to gum, skin, contaminated environment.Object of the present invention is just to provide a kind of toothbrush specialty biological antibiotic liquid, overcomes existing product deficiency, the obvious toothbrush antimicrobial fluid of non-stimulated, pollution-free, bactericidal effect.

background technologyas the saying goes that illness finds its way in by the mouth, oral cavity is the place that a various bacteria is assembled, if thereby the clean health that can cause not in time halitosis, various focusing depths represented, canker sore, decayed tooth, periodontosis various diseases harm people.So the clean of oral cavity is the first step of health of people health, so toothbrush also becomes the daily living article of people's indispensability.But show according to investigations, use the toothbrush of 3 weeks, bacterial number, up to 1,000,000, equals to surpass the amount of bacteria of 9 glasss of rag water, and the amount of bacteria of 29 monobasic coins, be 80 times of bowl water bacterial content! If exactly there is wound in your oral cavity, these bacteriums just very easily cause mouth disease.Even if there is no wound, a large amount of bacterial adhesion, on tooth, and are fully mixed with food in chewing, and will enter in body, equal to have drunk 9 glasss of addle, and the sterilization of visible toothbrush is the problem that people need to solve in a hurry.Oral cavity expert carried out detection to toothbrush for a long time, and had done bacterial culture, found to speckle with Candida albicans, hemolytic streptococcus, pneumobacillus and staphylococcus etc. on toothbrush.So expert advice, preferably every use is just thoroughly cleaned once for 15 days, does not give bacterium opportunity.But the most frequently used antibacterial, the degerming thimerosal of people is but the larger compositions of excitant such as hydrogen peroxide, Peracetic acid, chlorine peroxide, in to toothbrush gap, residual curing the disease be also larger to the injury of bristles body when dispelling, and if residual disinfectant do not have cleaning down totally the injury of tooth also to be can not be ignored.Toothbrush special bio antimicrobial fluid of the present invention can not have any injury to hair body in the bacterium of effectively dispelling between bristles body gap; and contained high activity material can decompose swill residual in toothbrush; residual antimicrobial fluid, to not injury of tooth, takes care of one's teeth.

summary of the inventionmain points of the present invention are to use various highly active biotic components mutually composite, and toothbrush is soaked in antimicrobial fluid, and bacterium residual in bristles body is killed.The formula following (component and percentage by weight % thereof) that the present invention selects: protein resolvase 4.0-6.0; Tea Polyphenols 6.0-8.0; Glucomannan 4.0-5.0; Shitosan 2.0-4.0; Alginase 3.0-5.0; Bacitracin 0.5-1.0; Rhein 4.0-6.0, purifies waste water to 100.

Glucomannan is a kind of antimicrobial component that contains nutriment, not only can provide diaphragm for tooth but also can suppress growing of bacterium in toothbrush gap; And protein resolvase is a kind of alkali protease, there is in vitro the function of solubilising protein, for residual swill between bristles body gap, there is decomposition, then that it is soluble in water, with current, wash away; Alginase is the high activity material extracting from the brown alga of edible ocean, has very strong stickiness, can adhere to the various bacteriums in toothbrush clinking, and bacterium is wrapped, and the breathing of anti-bacteria, makes bacterium dead; And alginase is harmless, degradable, belong to environmental protection except bacteria factor.Shitosan is the polycation derivative of chitin, interacts with the electronegative side chain of large biological molecule of pathogen cell surface, forms polymer, can affect the growth of pathogen and then inhibition pathogen; Also can directly enter the cell nucleus of pathogen, be combined syntheticly suppress its growth by what affect the mRNA of pathogen and protein with DNA, residual antimicrobial fluid enters shitosan to can be tooth behind oral cavity to provide calcareous, protects the health of one's teeth.

Bacitracin can destroy the cell membrane of noxious bacteria, causes bacterial body internal protein and nucleic acid irreversible denaturation, thereby causes that cell dysfunction causes bacterium dead; Also can anti-bacteria cell wall synthetic, especially to most of Gram-positive bacteria such as staphylococcus aureus, β hemolytic streptococcus etc. are extremely responsive.Rhein be from Chinese herbal medicine rheum officinale, extract pathogenic bacteria especially fungi are had to the material of efficient inhibition and killing action, can act on cell membrane, the cell nucleus of fungi, disturb the normal physiological function of pathogenic bacteria, make it dead fast.Tea Polyphenols is the general name of Polyphenols of Tea; comprise flavanol compound, anthocyanin class, flavonoids, flavonols and phenolic acid class; there is very strong antioxidation; can take care of one's teeth and avoid bacterium erosion; and be widely used in the preservative of food; therefore joining in the special-purpose antimicrobial fluid of toothbrush and can not injure people's human body, is a kind of antimicrobial component of green.

The preparation method of product of the present invention is:

1), gather fresh tea leaf in its, after cleaning, with acetone dipping, then leaching liquid is carried out to liquid---liquid extract and separate, the finally concentrated Tea Polyphenols powder that obtains;

2), rheum officinale is obtained to Rhein through cleaning, pulverizing, ethanol extraction;

3) weigh shitosan, in proportion, add in reactor, purify waste water to 100, stir;

4), proportionally protein resolvase, alginase are joined in reactor to stirring 15min;

5), glucomannan and bacitracin are proportionally mixed after, join slowly in reactor, the rotating speed of reactor is brought up to 120r/min;

6), the Tea Polyphenols having extracted, Rhein are proportionally joined in above-mentioned solution respectively slowly, after stirring, stop stirring;

7), take the dish out of the pot after, aseptic subpackaged.

The present invention has the following advantages: the antibacterial effect of (1) this product is remarkable, and through experiment, this product can reach 99.99% to the bacterium adhering in bristles body, fungi antibiotic rate; (2) swill residuing between toothbrush gap is had good decomposition and dispels effect; (3) biotype composition, to bristles body and not injury of oral cavity, can effectively prevent mouth disease, non-stimulated to mucous membrane of mouth; (4) easy to carry, the antibacterial and sterilization of toothbrush while can be used for going out, travelling; (5) concentrated type formula, is used content low, and technique is simple, and cost is low.

embodiment: below in conjunction with embodiment, the present invention is described in further detail:

According to following table institute column data (percentage by weight %) and described step thereof, be configured:

Formula one:

Protein resolvase 4.0-6.0

Tea Polyphenols 6.0-8.0

Glucomannan 4.0-5.0

Shitosan 2.0-4.0

Alginase 3.0-5.0

Bacitracin 0.5-1.0

Rhein 4.0-6.0

Purify waste water to 100

Formula two:

Protein resolvase 4.0-5.0

Tea Polyphenols 6.0-7.0

Glucomannan 4.0-4.5

Shitosan 2.0-3.0

Alginase 3.0-4.0

Bacitracin 0.5-0.7

Rhein 4.0-5.0

Purify waste water to 100

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Formula three:

Protein resolvase 5.0-6.0

Tea Polyphenols 7.0-8.0

Glucomannan 4.5-5.0

Shitosan 3.0-4.0

Alginase 4.0-5.0

Bacitracin 0.7-1.0

Rhein 5.0-6.0

Purify waste water to 100.

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Claims (2)

1. a toothbrush special bio antimicrobial fluid, is characterized in that having following formula (component and percentage by weight % thereof): protein resolvase 4.0-6.0; Tea Polyphenols 6.0-8.0; Glucomannan 4.0-5.0; Shitosan 2.0-4.0; Alginase 3.0-5.0; Bacitracin 0.5-1.0; Rhein 4.0-6.0, purifies waste water to 100.

2. a preparation method for toothbrush special bio antimicrobial fluid described in claim 1, is characterized in that having following step:

1), gather fresh tea leaf in its, after cleaning, with acetone dipping, then leaching liquid is carried out to liquid---liquid extract and separate, the finally concentrated Tea Polyphenols powder that obtains;

2), rheum officinale is obtained to Rhein through cleaning, pulverizing, ethanol extraction;

3) weigh shitosan, in proportion, add in reactor, purify waste water to 100, stir;

4), proportionally protein resolvase, alginase are joined in reactor to stirring 15min;

5), glucomannan and bacitracin are proportionally mixed after, join slowly in reactor, the rotating speed of reactor is brought up to 120r/min;

6), the Tea Polyphenols having extracted, Rhein are proportionally joined in above-mentioned solution respectively slowly, after stirring, stop stirring;

7), take the dish out of the pot after, aseptic subpackaged.