CN103645070A - Radial backflow-free gas sampling device for small animal breath test - Google Patents
Radial backflow-free gas sampling device for small animal breath test Download PDFInfo
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- CN103645070A CN103645070A CN201310663864.7A CN201310663864A CN103645070A CN 103645070 A CN103645070 A CN 103645070A CN 201310663864 A CN201310663864 A CN 201310663864A CN 103645070 A CN103645070 A CN 103645070A
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Abstract
The invention provides a radial backflow-free gas sampling device for a small animal breath test. The device comprises an animal fixing frame with experimental animals inside and fixed on the side wall of an experimental module; contamination gas flows from an experimental gas input port to an animal gas intake port and then enters noses of the animals, after the body circulation, the contamination gas is exhausted from a waste gas exhaust port, so as to realize the small animal breath test; the experiment module further is provided with a sampling jacket which is fixed on the side wall of the experimental module via the sampling gas intake port of the front end; the contamination gas flows to the sampling gas intake port from the experimental gas input port, forms radial gas flow along a test gas intake channel, flows through a sampler probe of a concentration detector, and then enters the sampling testing module to perform the contamination gas concentration continuous detection, the detected waste gas is exhausted to a waste gas module along a test gas outlet and then is exhausted by the waste gas exhaust port, so as to finish the detection. The device has the beneficial effects that the concentration of contamination substances in the small animal test experiment can be well detected conveniently, rapidly, exactly, rigorously and continuously without any backflow interference.
Description
Technical field
The invention provides a kind of toy respiration test uses radially without reflux gas sampling apparatus.
Background technology
Development along with science and technology and modernization of industry process, also brought the adverse consequences of gaseous environment pollution in the space of our life, people increase day by day for protection and the monitoring requirements of work and living environment simultaneously, medical research, environmental protection, chemical industry, that in the every field such as Military Application, carries out utilizes more extensively more deep that the scientific experiments such as toy respiration test research toxicology and curative effect of medication carry out, the suction filter membrane Weighing method adopting for the concentration people of the gas of contaminating in better determination experiment, suction bubbling absorption liquid, colourimetry etc. classic method is carried out the indirect determination inconvenience of concentration, there is error, can not monitor continuously, reflux gas disturbs result accuracy etc. disadvantage to affect the accurate quantitative analysis science of toy respiration test, in the application in this field, be affected and restriction becomes when last large technical barrier, in order to solve this technical barrier, improve existing sampling and mensuration mode, can be easily and fast, accurately rigorous, uninterrupted continuously, that without any backflow, disturbs is good by contained contamination matter concentration measuring in breathing gas in toy respiration test, develop a kind of toy respiration test with radially becoming current urgent needs without reflux gas sampling apparatus.
Summary of the invention
For addressing the above problem, the object of this invention is to provide a kind of toy respiration test with radially without reflux gas sampling apparatus, can be easily and fast, accurate rigorous, continual, without any backflow interference the matter concentration measuring of contaminating in toy respiration test is good continuously.
For achieving the above object, the technical solution used in the present invention is to comprise that the animal fixed mount that an inside is housed by the animal used as test animal by front end sucks gas port and is seated on the Laboratory Module sidewall fixing in having external seal cushion rubber and interior O-ring seal, contamination gas can flow into from experimental gas input port animal and suck gas port and to breathing out gas circulation in the nose of animal used as test and body, to animal exhalation gas port, be discharged into combustion gas cabin again and discharged toy respiration test via combustion gas mouth, the sampling chuck of the same gas flow pattern of simulated experiment animal breath is installed on another sidewall of Laboratory Module, sampling air entry by front end is seated and fixes in having external seal cushion rubber and interior O-ring seal on Laboratory Module sidewall, contamination gas can flow in sampling chuck up-sampling air entry and form radial air flow from the top down along test air intake duct from experimental gas input port, the sampling thief probe that this radial air flow flows through the sampling sensor that is arranged on the concentration detector with continuous detecting function in interior separation layer enters the sampling test chamber gas concentration of contaminating and detects, from the sampling test chamber waste gas of gas concentration detecting of contaminating, flow out to the test cabin of giving vent to anger and be discharged into combustion gas cabin along testing out gas port, via combustion gas mouth, discharge, easily and fast, accurately rigorous, uninterrupted continuously, contained contamination material concentration in breathing gas in the determination experiment animal breath experiment of disturbing without any backflow.
The invention has the beneficial effects as follows that having developed a kind of toy respiration test uses radially without reflux gas sampling apparatus, solved the suction filter membrane Weighing method adopting in the past, suction bubbling absorption liquid, colourimetry etc. classic method is carried out the indirect determination inconvenience of concentration, there is error, can not monitor continuously, reflux gas disturbs result accuracy etc. disadvantage and has affected the accurate quantitative analysis science of toy respiration test, a large technical barrier that is affected in the application in this field and restricts, existing sampling and mensuration mode have been improved, having met can be easily and fast, accurately rigorous, uninterrupted continuously, without any backflow, disturb by the good urgent needs of contained contamination matter concentration measuring in breathing gas in toy respiration test, in medical research, environmental protection, chemical industry, utilizing in the scientific experiment researchs such as toy respiration test research toxicology and curative effect of medication of carrying out in the every field such as Military Application is used widely.
Accompanying drawing explanation
Accompanying drawing is a kind of toy respiration test of the present invention with radially without the structural representation of reflux gas sampling apparatus
In figure:
1. experimental gas input port 2. animals suck gas port 3. animal fixed mount 4. animals used as test
5. animal exhalation gas port 6. concentration detector 7. Laboratory Module inner sleeve 8. combustion gas mouths
9. combustion gas cabin 10. Laboratory Module 11. external seal cushion rubbers 12. test out gas port
13. interior separation layers 14. test out air flue 15. sampling chuck 16. sampling test chambers
17. sampling thiefs, the 18. sampled data line 19. sampling thief handle 20. double sealing circles of popping one's head in
21. sampling sensor 22. radial air flow 23. test air intake ducts 24. are tested the cabin of giving vent to anger
25. interior O-ring seal 26. sampling air entries.
Embodiment
By reference to the accompanying drawings and embodiment to a kind of toy respiration test of the present invention with being radially illustrated without reflux gas sampling apparatus structure.
As shown in Figure 1, the invention provides a kind of toy respiration test uses radially without reflux gas sampling apparatus, comprise that the animal fixed mount 3 that an inside is housed by animal used as test 4 animal by front end sucks gas port 2 and is seated on Laboratory Module 10 sidewalls that fix in having external seal cushion rubber 11 and interior O-ring seal 25, in 3 one of animal fixed mounts are made by resistant material, the cylindrical cavity of the bright and clean easy cleaning of outside surface, animal used as test 4 sealings of accepting respiration test are fixed on to inside, at the rear portion of cylindrical cavity, have the aperture that can stretch out tail, the front end of cylindrical cavity has the tubular type animal of a protrusion to suck gas port 2, animal sucks the physical dimension of gas port 2 and the small sircle hole fitted seal that interior O-ring seal 25 is installed in Laboratory Module inner sleeve 7, the big hole fitted seal that external seal cushion rubber 11 is installed on the physical dimension of animal fixed mount 3 front ends and Laboratory Module 10, in 10 1 of Laboratory Modules are made by resistant material, the composite cavity of the bright and clean easy cleaning of outside surface, penetralia is the Laboratory Module inner sleeve 7 of an airtight cavity structure, outwards have the experimental gas input port 1 that can introduce contamination gas, surrounding in Laboratory Module inner sleeve 7 has the small sircle hole that a plurality of internal diameters of evenly arranging and animal suction gas port 2 and sampling air entry 26 match, interior O-ring seal 25 is installed in small sircle hole and can plays sealing and fixation, the Laboratory Module 10 coaxially connecting is surrounded in the outside seal of Laboratory Module inner sleeve 7, Laboratory Module 10 surroundings evenly arranging with Laboratory Module inner sleeve 7 on the same quantity of little perforate of interior O-ring seal 25 a plurality of big holes of perforate on coaxial position are housed, the internal diameter size of big hole and animal fixed mount 3 are suitable with sampling chuck 15 outside dimensions, and by the external seal cushion rubber 11 being arranged in big hole, animal fixed mount 3 and 15 sealings of sampling chuck are fixed on Laboratory Module 10 sidewalls, the outside of Laboratory Module 10 has a combustion gas cabin 9 and is connecting combustion gas mouth 8 discharging waste gas, contamination gas flow into animal and sucks gas port 2 and to breathing out gas circulation in the nose of animal used as test 4 and body, to animal exhalation gas port 5, be discharged into combustion gas cabin 9 and discharged toy respiration test via combustion gas mouth 8 from experimental gas input port 1, simulated experiment animal 4 is installed on Laboratory Module 10 another sidewalls and breathes the sampling chuck 15 of same gas flow pattern, in 15 1 of chucks of sampling are made by resistant material, the cylindrical cavity of the bright and clean easy cleaning of outside surface, the sampling thief probe 17 that the sampling sensor 21 of the concentration detector 6 with continuous detecting function can be installed enters sampling test chamber 16 gas concentration of contaminating and detects, the front end of cylindrical cavity has the tubular type sampling air entry 26 of a protrusion, the physical dimension of sampling air entry 26 and the small sircle hole fitted seal that interior O-ring seal 25 is installed in Laboratory Module inner sleeve 7, the physical dimension of sampling chuck 15 front ends and the big hole fitted seal that external seal cushion rubber 11 is installed on Laboratory Module 10, in sampling chuck 15 rear ends, have and the sampling thief middle circular hole that 17 diameter dimensions match of popping one's head in, double sealing circle 20 sealing is installed in middle circular hole to be fixed sampling thief probe 17 and also just fixes whole concentration detector 6, the sampling air entry 26 of whole sampling chuck 15 by front end is seated to fix to be had on interior Laboratory Module 10 sidewalls of external seal cushion rubber 11 and interior O-ring seal 25, contamination gas flow into from experimental gas input port 1 and sampling chuck 15, then along sampling chuck 15 inside, has and the test air intake duct 23 of the upwards amplification that air entry 26 sealing of sampling is communicated with flows and forms radial air flow 22 from the top down, the sampling thief probe 17 that this radial air flow 22 flows through the sampling sensor 21 that is arranged on the concentration detector with continuous detecting function 6 in interior separation layer 13 enters sampling test chamber 16 gas concentration of contaminating and detects, test air intake duct 23 terminals face the sampling thief probe 17 being placed in middle circular hole under shed, the concentration value data that detect are sent to record and demonstration on corresponding instrument by the sampled data line 18 of drawing on sampling thief handle 19, the air flue 14 guiding test airflow that test out of contaminating from sampling test chamber 16 that the waste gas of gas concentration detecting flows out to that the following opening of sampling test chamber 16 is tightly connected arrive the test cabin 24 of giving vent to anger, then along testing out gas port 12, be discharged into combustion gas cabin 9, via 8 discharges of combustion gas mouth, easily and fast, accurately rigorous, uninterrupted continuously, completing contained contamination matter concentration measuring in breathing gas in toy respiration test of disturbing without any backflow is good.
Embodiment:
Use a kind of toy respiration test of the present invention breathe exposure experiment and radially without backflow sampling work, should first the toy of experiment use and contamination gas sample be ready to radially carrying out animal used as test 4 without reflux gas sampling apparatus, what contamination gas sample was sealably coupled to Laboratory Module inner sleeve 7 tops install outwards has on the experimental gas input port 1 that can introduce contamination gas, the ready toy of accepting respiration test is sealed successively and is fixed in animal fixed mount 3, in 3 one of animal fixed mounts are made by resistant material, the cylindrical cavity of the bright and clean easy cleaning of outside surface, at the rear portion of cylindrical cavity, have the aperture that can stretch out tail, the front end of cylindrical cavity has the tubular type animal of a protrusion to suck gas port 2, animal sucks the physical dimension of gas port 2 and the small sircle hole fitted seal that interior O-ring seal 25 is installed in Laboratory Module inner sleeve 7, the big hole fitted seal that external seal cushion rubber 11 is installed on the physical dimension of animal fixed mount 3 front ends and Laboratory Module 10, the tubular type animal of the protrusion of the big hole that external seal cushion rubber 11 is installed by the animal fixed mount 3 that installs animal used as test 4 on Laboratory Module 10 and the front end of cylindrical cavity sucks gas port 2 and is inserted into sealing on Laboratory Module 10 and fixes, same method installs sampling chuck 15 on Laboratory Module 10 another sidewalls, simultaneously in sampling chuck 15 has the middle circular hole of double sealing circle 20, sealing fixes sampling thief probe 17, also just can install and fix the whole concentration detector 6 with continuous detecting function, the sampled data line 18 of drawing on sampling thief handle 19 is connected on corresponding detecting instrument, check the connection sealing of whole system intact errorless after, unlatching contamination gas sample conveying device by experiment gas input port 1 is carried contamination gases to Laboratory Module inner sleeve 7, contamination gas flow into animal and sucks gas port 2 and to animal exhalation gas port 5, be discharged into combustion gas cabin 9 to breathing out gas circulation in animal used as test 4 noses and body from experimental gas input port 1, via combustion gas mouth 8, discharged toy respiration test, the gas concentration of meanwhile contaminating detects also carries out continuous detecting synchronously, contamination gas flow into sampling chuck 15 from experimental gas input port 1, then along sampling chuck 15 inside, have and the test air intake duct 23 of the upwards amplification that air entry 26 sealing of sampling is communicated with flows, test air intake duct 23 terminals face the sampling thief probe 17 being placed in middle circular hole under shed, 16 perforates of sampling test chamber form radial air flow 22 downwards and by real-time continuous, are detected when by sampling sensor 21, the concentration value data that detect are sent to record and demonstration on corresponding instrument by the sampled data line 18 of drawing on sampling thief handle 19, that from sampling test chamber 16, contaminates that the waste gas of gas concentration detecting flows out to that the following opening of sampling test chamber 16 is tightly connected tests out air flue 14, guiding test airflow arrives tests the cabin 24 of giving vent to anger, then along testing out gas port 12, be discharged into combustion gas cabin 9, via 8 discharges of combustion gas mouth, can be easily and fast in whole experimentation, accurately rigorous, uninterrupted continuously, that without any backflow, disturbs completes in animal used as test 4 respiration tests the mensuration of contained contamination material concentration in breathing gas, completing contamination closes after respiration test and disconnects contamination gas sample conveying device, cut off experimental gas input port 1 and to Laboratory Module inner sleeve 7, carry the air-flow of contamination gas, take off the animal fixed mount 3 that installs animal used as test 4, and the toy that discharges experiment use carries out next step observation and testing, take off mounted sampling chuck 15 on Laboratory Module 10 another sidewalls, then take out the sampling thief probe 17 that in the middle circular hole that is placed in the inherent double sealing circle 20 of sampling chuck 15, sealing fixes, also just can take down the whole concentration detector 6 with continuous detecting function, the sampled data line 18 of drawing on sampling thief handle 19 is disconnected from corresponding detecting instrument, the respiration test concentration data obtaining in experimentation is carried out to next step storage and analysis.
Claims (4)
1. a toy respiration test is used radially without reflux gas sampling apparatus, it is characterized in that: this equipment comprises that the animal fixed mount (3) that an inside is housed by animal used as test (4) animal by front end sucks gas port (2) and is seated to be fixed on and has on external seal cushion rubber (11) and interior Laboratory Module (10) sidewall of interior O-ring seal (25), contamination gas can flow into animal from experimental gas input port (1) and suck gas port (2) and to exhalation gas circulation in the nose of animal used as test (4) and body, to animal exhalation gas port (5), be discharged into combustion gas cabin (9) again and discharged toy respiration test via combustion gas mouth (8), the sampling chuck (15) that simulated experiment animal (4) breathes same gas flow pattern is installed on another sidewall of Laboratory Module (10), sampling air entry (26) by front end is seated and fixes in having external seal cushion rubber (11) and interior O-ring seal (25) on Laboratory Module (10) sidewall, contamination gas flow in sampling chuck (15) up-sampling air entry (26) and forms radial air flow (22) from the top down along test air intake duct (23) from experimental gas input port (1), the sampling thief probe (17) that this radial air flow (22) flows through the sampling sensor (21) that is arranged on the concentration detector with continuous detecting function (6) in interior separation layer (13) enters sampling test chamber (16) gas concentration of contaminating and detects, from sampling test chamber (16) waste gas of gas concentration detecting of contaminating, flow out to the test cabin (24) of giving vent to anger and be discharged into combustion gas cabin (9) along testing out gas port (12), via combustion gas mouth (8), discharge, easily and fast, accurately rigorous, uninterrupted continuously, contained contamination material concentration in breathing gas in determination experiment animal (4) respiration test disturbing without any backflow.
2. a kind of toy respiration test according to claim 1 is used radially without reflux gas sampling apparatus, it is characterized in that: in (10) one of described Laboratory Modules are made by resistant material, the composite cavity of the bright and clean easy cleaning of outside surface, penetralia is the Laboratory Module inner sleeve (7) of an airtight cavity structure, outwards have the experimental gas input port (1) that can introduce contamination gas, surrounding in Laboratory Module inner sleeve (7) has the small sircle hole that a plurality of internal diameters of evenly arranging and animal suction gas port (2) and sampling air entry (26) match, interior O-ring seal (25) is installed in small sircle hole and plays sealing and fixation, the Laboratory Module (10) coaxially connecting is surrounded in the outside seal of Laboratory Module inner sleeve (7), Laboratory Module (10) surrounding evenly arranging with Laboratory Module inner sleeve (7) on the same quantity of little perforate of interior O-ring seal (25) a plurality of big holes of perforate on coaxial position are housed, the internal diameter size of big hole and animal fixed mount (3) are suitable with sampling chuck (15) outside dimension, and by the external seal cushion rubber (11) being arranged in big hole, animal fixed mount (3) and sampling chuck (15) sealing are fixed on the sidewall of Laboratory Module (10), the outside of Laboratory Module (10) has a combustion gas cabin (9) and is connecting a combustion gas mouth (8) discharging waste gas.
3. a kind of toy respiration test according to claim 1 is used radially without reflux gas sampling apparatus, it is characterized in that: in (3) one of described animal fixed mounts are made by resistant material, the cylindrical cavity of the bright and clean easy cleaning of outside surface, animal used as test (4) sealing of accepting respiration test is fixed on to inside, at the rear portion of cylindrical cavity, have the aperture that can stretch out tail, the front end of cylindrical cavity has the tubular type animal of a protrusion to suck gas port (2), animal sucks the physical dimension of gas port (2) and the small sircle hole fitted seal that interior O-ring seal (25) is installed in Laboratory Module inner sleeve (7), the physical dimension of animal fixed mount (3) front end and the big hole fitted seal that external seal cushion rubber (11) is installed on Laboratory Module (10).
4. a kind of toy respiration test according to claim 1 is used radially without reflux gas sampling apparatus, it is characterized in that: in (15) one of described sampling chucks are made by resistant material, the cylindrical cavity of the bright and clean easy cleaning of outside surface, the sampling thief probe (17) of sampling sensor (21) that installation has a concentration detector (6) of continuous detecting function enters sampling test chamber (16) gas concentration of contaminating and detects, the front end of cylindrical cavity has the tubular type sampling air entry (26) of a protrusion, the physical dimension of sampling air entry (26) and the small sircle hole fitted seal that interior O-ring seal (25) is installed in Laboratory Module inner sleeve (7), the physical dimension of sampling chuck front end and the big hole fitted seal that external seal cushion rubber is installed on Laboratory Module, in sampling chuck (15) rear end, have the middle circular hole that the diameter dimension with sampling thief probe (17) matches, double sealing circle (20) sealing is installed in middle circular hole to be fixed sampling thief probe (17) and also just fixes whole concentration detector (6), contamination gas has along sampling chuck (15) inside and the test air intake duct (23) of the upwards amplification that the air entry of sampling (26) sealing is communicated with flows, that tests air intake duct (23) terminal faces under shed the sampling thief probe (17) being placed in middle circular hole, the perforate of sampling test chamber (16) forms radial air flow (22) downwards and by real-time continuous, is detected when the sampling sensor by concentration detector (6) (21), the concentration value data that detect are sent to record and demonstration on corresponding instrument by the sampled data line (18) of drawing on sampling thief handle (19), sampling test chamber (16) following opening is tightly connected and tests out air flue (14) guiding test airflow and arrive the test cabin (24) of giving vent to anger, then by testing out gas port (12) arrival combustion gas cabin (9), by combustion gas mouth (8), emit.
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| CN201310663864.7A CN103645070B (en) | 2013-12-10 | 2013-12-10 | A kind of toy respiration test is used radial without reflux gas sampling apparatus |
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| CN103645070B CN103645070B (en) | 2015-12-30 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109767679A (en) * | 2019-01-14 | 2019-05-17 | 厦门大学 | A kind of breathing apparatus |
| CN112857924A (en) * | 2021-04-09 | 2021-05-28 | 军事科学院军事医学研究院军事兽医研究所 | Small and medium-sized experimental animal exhaled aerosol collection system |
| CN117136857A (en) * | 2023-10-23 | 2023-12-01 | 佳木斯大学 | Sampling device for small animal breath experiment |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109767679A (en) * | 2019-01-14 | 2019-05-17 | 厦门大学 | A kind of breathing apparatus |
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| CN117136857A (en) * | 2023-10-23 | 2023-12-01 | 佳木斯大学 | Sampling device for small animal breath experiment |
| CN117136857B (en) * | 2023-10-23 | 2024-01-09 | 佳木斯大学 | Sampling device for small animal breath experiment |
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