CN103623327B - Point-application Chinese medicine for the treatment of infantile anorexia and preparation method thereof - Google Patents

Point-application Chinese medicine for the treatment of infantile anorexia and preparation method thereof Download PDF

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Publication number
CN103623327B
CN103623327B CN201310507162.XA CN201310507162A CN103623327B CN 103623327 B CN103623327 B CN 103623327B CN 201310507162 A CN201310507162 A CN 201310507162A CN 103623327 B CN103623327 B CN 103623327B
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parched
spleen
fructus
parts
stomach
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CN103623327A (en
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邵秀英
贾晓
宋金芳
张倩
贾琳
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Qingdao Huangdao District Healthcare Hospital For Women Children
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Abstract

Treat a point-application Chinese medicine for infantile anorexia, be grouped into by the one-tenth of following mass fraction: Rhizoma Atractylodis Macrocephalae (parched) 3 parts, Fructus Amomi 2 parts, Fructus Amomi Rotundus 2 parts, Fructus Crataegi (parched to brown) 1 part, Fructus Hordei Germinatus (parched) 1 part, live chickens Endothelium corneum 1 part.Primary disease treatment with " spleen strong be valued for fortune and not in benefit " for guideline, main with invigorating the spleen and regulating the stomach, can not cross with tonification or simple food stagnation removing.Rhizoma Atractylodis Macrocephalae (parched) air making-up and spleen enlivening is monarch drug, Fructus Amomi, and roud cardamon seed fragrance warming middle-JIAO to promote flow of QI of being amusing is ministerial drug, helps Rhizoma Atractylodis Macrocephalae (parched) spleen invigorating, makes spleen energy transporting; Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), live chickens Endothelium corneum promoting digestion and invigorating the stomach is adjuvant drug, can help Rhizoma Atractylodis Macrocephalae (parched) spleen invigorating transporting and transforming nutrients from foodstuff.Full side plays spleen invigorating warming middle-JIAO to promote flow of QI altogether, the merit of promoting digestion and invigorating the stomach.Such temper is healthy and vigorous, and stomach receives enhancing, and appetite strengthens, and food has taste like this, and QI and blood biochemistry is active.

Description

Point-application Chinese medicine for the treatment of infantile anorexia and preparation method thereof
Technical field
The present invention relates to a kind of external application Chinese medicine, particularly one sticks the Chinese medicine being used for the treatment of infantile anorexia in Pishu (bilateral), bl (bilateral), SHENQUE acupoint place.
Background technology
Infantile anorexia (disordersofdigestivefunction) also known as digestive functional disturbance, clinical manifestation with the loss of appetite of long term even refusing to eat for principal character.Be apt to occur in 1 ~ 6 years old child, especially more common with city children's, the sickness rate of only child is higher.Morbidity without obviously seasonal, but summer heat-damp in summer in season, can exacerbation of symptoms be made.Clinically, often there is head of a family's private prosecution child appetite bad, obtain " apositia "? in fact, be not just be diagnosed as " apositia " with " inappetence ", so-called apositia, first must get rid of baby and whether suffer from flu or internal medicine chronic disease (such as: have loose bowels for a long time, chronic hepatitis, pulmonary tuberculosis), if because above-mentioned reason, anorexia is now natural, and after disease recovery from illness by the time, anorexia should be able to be improved; Apositia truly must be after eliminating children's suffers from the physiological disorders such as flu, internal medicine chronic disease or digestive tract disease, over a long time inappetence, see that food is not wanted to eat, even refuse to eat yet, this situation generally continuous more than two months, so, just meet so-called " anorexia ".
The cause of disease of infantile anorexia has a lot, and bad dietary habit is often the main cause of anorexia, and the diet of high protein, high sugar makes appetite decline; Two meal between arbitrarily eat the snacks such as confection, dessert, Semen arachidis hypogaeae, Semen Benincasae, and variable interval of having a meal, the irregular appetite that all affects of living, add the head of a family's spoiling only child, overflow into nourishing, taste biochemical function of a specified duration is not normal.Some father and mother be also eager to excel feed, curse and beat, more cause children's's psychentonia, nutritional disorders, occur that body is more weak, natural fibre line of meat sweating due to debility is many, lustreless complexion symptom.Through examining, find that the clean tongue of the most tongue of infant is few, the soft nothing of abdomen is amassed, and defecates hard, heating easy to catch cold.Primary disease can not get alleviating for a long time, can complication infantile malnutrition, even causes dysplasia etc.Children's is in continuous growth promoter, and the adult that compares needs more various allowance of nutrients.If various allowance of nutrients is not enough, the normal growth that not only can affect children's is grown, and makes growth promoter stagnate, internal organs of the body atrophy, will inevitably affect the normal immune system of children's like this time serious.As due to anorexia caused serious protein--heat energy is not enough malnutrition infant, can occur that Cellular Immune Disturbances and serum antibody reduce, thus easily the infection such as various antibacterial, virus and fungus occur, and infection often continue, protracted course of disease, even threat to life.Clinical manifestation is repeated cold, fever, or recurrent cough, do not eat, not active, body weight does not increase, and size is not long.
According to the theory of Chinese medical science of China, infantile anorexia belongs to " indigestion and loss of appetite " of the traditional Chinese medical science, " anorexia " category, the traditional Chinese medical science thinks that The spleen and stomach provide the material basis of the acquired, source of generating QI and blood, The spleen has the function to transport and transform nutrients, stomach receiving food and drink, The spleen has the function to transport and transform nutrients water paddy, The spleen has the function to transport and transform nutrients water liquid, temper is healthy and vigorous, and stomach receives officials, famine is full often to be had, and QI and blood biochemistry is active.Children's is the body of immature yin and yang, and internal organs are tender and lovely, and children's is due to eating and drinking without temperance usually, and improper feeding, long-term monophagia or hungryly fullly immoderately injure in taste, cause taste impaired, dysfunction of the spleen in transportation, stomach loses and received, and produces anorexia, food and tasteless apositia.Primary disease treatment with " spleen strong be valued for fortune and not in benefit " for guideline, main with invigorating the spleen and regulating the stomach, can not cross with tonification or simple food stagnation removing.
Current clinical treatment infantile anorexia is all generally adopt medicine for oral administration to treat, and Western medicine kind for oral administration is a lot, but major part not only price is partially expensive but also effect is mostly not obvious, can not effect a radical cure, side effect is large, life-time service even can impair one's health, and the Chinese medicine of existing treatment infantile anorexia, be mostly oral medicine, the good Chinese patent medicine of some mouthfeel, such as JIANWEI XIAOSHI PIAN, mostly just play appetizing and digestive effect, cure the symptoms, not the disease, and the Chinese medicine effected a permanent cure, mostly mouthfeel is not good enough, the such as patent No. be 200710068406.3 patent of invention disclose a kind of medicine for the treatment of infantile anorexia and preparation method thereof, method, its component has: Massa Medicata Fermentata 21-29 part, Jiaoshan Hill plants 18-26 part, Fructus Hordei Germinatus 15-25 part, Endothelium Corneum Gigeriae Galli 20-27 part, Radix Puerariae 15 1 20 parts, Rhizoma Zingiberis 12 1 16 parts, Flos Lonicerae 14 1 19 parts, astragalus 15-20 part, fry Fructus Aurantii 10 1 13 parts, preparation method: Massa Medicata Fermentata use water is steamed limit steam distillation method and extracts volatile oil, medicinal residues and residue 8 kinds of medical materials merge, decoct with water 2-3 time, each 25-35 minute, collecting decoction, be evaporated to thick paste, put to room temperature, with alcohol settling, gained concentrated solution mixes with Massa Medicata Fermentata volatile oil, add white sugar and starch, mix homogeneously, drying under reduced pressure, packaging, sterilizing, sealing, namely obtain.This medicine not only complicated components, dosage is many and preparation method complicated.This medicine is oral medicine, and children's is anorexia inherently, just unwilling even more oral drugs, and adopt this kind of method treatment, infant is often mismatched, and also may can play minus effect.
Now some are also had to treat the medicine of infantile anorexia by external application, the such as patent No. be 201210047599.5 patent of invention disclose a kind of ointment for the treatment of infantile anorexia, by Fructus Gardeniae 25-35 gram, Fructus Crataegi 25-35 gram, Semen Arecae 25-35 gram, raw Semen Armeniacae Amarum 25-35 gram, make with azone for Borneolum Syntheticum 8-12 gram, wherein, by Fructus Gardeniae, Fructus Crataegi, Semen Arecae and raw Semen Armeniacae Amarum are dried mixing and are ground, cross 80-120 mesh sieve and become fine powder A, again Borneolum Syntheticum is ground, cross 80-120 mesh sieve and become fine powder B, fine powder A and fine powder B is mixed into medicamental pulverata, add azone again and mix ointment by all even for medicamental pulverata, the pill of spheronizing, every ball adds 2.5-3g azone by 15-20g medicamental pulverata and makes.In this medicine, transdermal penetration enhancer uses azone, and it is for the low stimulation of low toxicity during normal skin, and it can also promote that skin is to the absorption of medicine, makes dosage reduce.But it can produce obvious stimulation for damaged skin place.Children's in application process may due to medicine in other component produce and stimulate, and then grab rich, drug of topical application place skin injury may be caused, adding that the effect of azone can further chafe, produce the reaction such as irritated.And this process for preparing medicine is more complicated, azone and medicine directly mix rear for subsequent use, are not only difficult to preserve, and the preservable time is short.
The patent No. be 200810190917.7 patent of invention disclose a kind of external prescription for the treatment of infantile anorexia, the weight proportion of its each component is: Fructus Hordei Germinatus (parched) 8-10, Jiaoshan Hill quarrel 10-15, Massa Medicata Fermentata preparata 8-12, fry Endothelium corneum 5-10, fry Semen Raphani 7-12, flour 9-14.Remaining is distilled water.Preparation method: by Fructus Hordei Germinatus (parched), Jiaoshan Hill quarrel, Massa Medicata Fermentata preparata, stir-fry, fry Semen Raphani pulverize, add flour and distilled water furnishing pasty state is applied on gauze, spread on umbilicus place just before going to bed at infant at every turn.The composition promoting that skin absorbs the drug is there is no, so this medicine using dosage is large in this pharmaceutical ingredients.Due at embryonic stage, umbilical part is that fetus is communicated with parent, and obtain unique passage of blood, oxygen and nutrition supply, though this passage is broken off after birth, umbilical part and whole body meridian, the vital organs of the human body still have very close relationship.Umbilicus is the place that stomach wall is the thinnest, does not have subcutaneous fat, and blood vessel is very abundant, so this medicine is affixed on umbilicus place can play therapeutical effect, and other point skins can treating infantile anorexia of health are thicker, if this plaster is spread on other acupuncture point places, curative effect can be poor.
Summary of the invention
The present invention is directed to the deficiency of prior art, provide that a kind of formula can treating infantile anorexia is simple, dosage is few, be convenient to preparation and preserve and use, be easy to permeate, instant effect good with absorption, therapeutic effect, avoid the point-application Chinese medicine of taking medicine of having an injection.
Technical scheme of the present invention is: a kind of point-application Chinese medicine for the treatment of infantile anorexia, is grouped into by the one-tenth of following mass fraction: Rhizoma Atractylodis Macrocephalae (parched) 3 parts, Fructus Amomi 2 parts, Fructus Amomi Rotundus 2 parts, Fructus Crataegi (parched to brown) 1 part, Fructus Hordei Germinatus (parched) 1 part, live chickens Endothelium corneum 1 part.
The preparation method of the point-application Chinese medicine of above-described treatment infantile anorexia, is characterized in that: comprise the following steps:
(1), according to mass fraction, Rhizoma Atractylodis Macrocephalae (parched) 3 parts, Fructus Amomi 2 parts, Fructus Amomi Rotundus 2 parts, Fructus Crataegi (parched to brown) 1 part, Fructus Hordei Germinatus (parched) 1 part, live chickens Endothelium corneum 1 part is taken;
(2), above-mentioned load weighted component is pulverized respectively after, cross 100 mesh sieve, obtain satisfactory powder;
(3), by after above-mentioned powder mixing and stirring, load in sealed container and preserve.
The using method of the point-application Chinese medicine of above-described treatment infantile anorexia, is characterized in that: during use, gets medicine powder and is placed in clean container, after Rhizoma Zingiberis Recens juice furnishing pasty state, is made into the medicine cake of 2cm × 2cm, for subsequent use.
The invention has the beneficial effects as follows: according to the theory of Chinese medical science of China, infantile anorexia belongs to " indigestion and loss of appetite " of the traditional Chinese medical science, " anorexia " category, the traditional Chinese medical science thinks that The spleen and stomach provide the material basis of the acquired, source of generating QI and blood, The spleen has the function to transport and transform nutrients, stomach receiving food and drink, The spleen has the function to transport and transform nutrients water paddy, The spleen has the function to transport and transform nutrients water liquid, temper is healthy and vigorous, and stomach receives officials, famine is full often to be had, and QI and blood biochemistry is active.Children's is the body of immature yin and yang, and internal organs are tender and lovely, and children's is due to eating and drinking without temperance usually, and improper feeding, long-term monophagia or hungryly fullly immoderately injure in taste, cause taste impaired, dysfunction of the spleen in transportation, stomach loses and received, and produces anorexia, food and tasteless apositia.
Primary disease treatment with " spleen strong be valued for fortune and not in benefit " for guideline, main with invigorating the spleen and regulating the stomach, can not cross with tonification or simple food stagnation removing.In side, the Rhizoma Atractylodis Macrocephalae is bitter, sweet, warm, returns spleen, stomach warp.There is the effect of air making-up and spleen enlivening." book on Chinese herbal medicine converges and says ": " Rhizoma Atractylodis Macrocephalae is assignment taste, and wet dissipation eliminating impediment, helps digestion except the key medicine of painful abdominal mass.Insufficiency of the spleenly be not good for, art can mend it, and insufficiency of stomach is not received, and art can help it." Rhizoma Atractylodis Macrocephalae power of mending stomach spleen invigorating through parching with earth or parched with bran is stronger.
Fructus Amomi is pungent, warm, returns spleen, stomach warp.There is the effect that warming middle-JIAO to promote flow of QI fragrance is amusing." property of medicine opinion ": " main cold air stomachache ....Disappear digesting and absorbing the essence of foodstuff, warm taste." modern pharmacological research Fructus Amomi volatile oil has fragrant digestion promoting function, can gastric secretion be promoted, digestive tract pneumatosis can be got rid of, therefore can relieving distension by promoting circulation of QI.Fructus Amomi Rotundus property is pungent, warm, returns spleen, stomach, lung meridian.There is removing dampness circulation of qi promoting, the effect that warming middle-JIAO is amusing." Kaibao Bencao ": " main accumulation of pathogenic cold gas, emesis regurgitation, the rapid digestion of food therapeutic method to keep the adverse QI flowing downwards." pharmacological research this product is containing volatile oil now, wherein main component is dextro Borneolum Syntheticum and gum camphor.This product can promote gastric secretion, promotes gastrointestinal peristalsis, prevents enteral abnormal fermentation, drives away gastrointestinal pneumatosis, therefore has good fragrant digestion promoting function.
Fructus Crataegi property is sour, sweet, tepor returns taste Liver Channel, has the effect of promoting digestion and removing stagnation circulation of qi promoting dissipating blood stasis.Compendium of Material Medica: " dissipating fluid-retention is eaten.Disappear meat Ji , mass in the abdomen phlegm retention, feeling of fullness acid regurgitation, stagnant blood pain with distension." modern pharmacological research Fructus Crataegi can increase the secretion of digestive enzyme in stomach, facilitating digestion.Contained lipase can promote steatolysis.Contained multiple organic acid can improve the activity of protease, and food meat is easily digested.
Fructus Hordei Germinatus is sweet flat, returns spleen, stomach, Liver Channel.There is promoting digestion and invigorating the stomach, the effect of galactopoiesis relieving distension.Compendium of Material Medica: " digest all fruit food stagnations of all rice and flour." modern pharmacological research this product amylase-containing, conversion carbohydrase, proteolytic enzyme, vitamin B, maltose, glucose, phospholipid and micro-hordenine etc.Digestive enzyme contained by it and the peptic effect of vitamin B.
Endothelium Corneum Gigeriae Galli, sweet, flat, return spleen, stomach, small intestinal, urinary bladder channel, there is the effect of promoting digestion and invigorating the stomach.Compendium of Material Medica: " control children's's intermittent fever due to retention of food, treat the dripping regurgitation of adult, the wine that disappears amasss ... " modern pharmacological research this product is containing gastric hormone, keratin, aminoacid and micro-pepsin, amylase etc.After oral Endothelium Corneum Gigeriae Galli powder, the secretory volume of gastric juice, acidity and eupepsy all increase, and stomach motion is strengthened, emptying quickening.Live chickens Endothelium corneum is better than the food digesting action of Endothelium Corneum Gigeriae Galli (parched).
Rhizoma Atractylodis Macrocephalae (parched) air making-up and spleen enlivening is monarch drug, Fructus Amomi, and roud cardamon seed fragrance warming middle-JIAO to promote flow of QI of being amusing is ministerial drug, helps Rhizoma Atractylodis Macrocephalae (parched) spleen invigorating, makes spleen energy transporting; Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), live chickens Endothelium corneum promoting digestion and invigorating the stomach is adjuvant drug, can help Rhizoma Atractylodis Macrocephalae (parched) spleen invigorating transporting and transforming nutrients from foodstuff.Full side plays spleen invigorating warming middle-JIAO to promote flow of QI altogether, the merit of promoting digestion and invigorating the stomach.Such temper is healthy and vigorous, and stomach receives enhancing, and appetite strengthens, and food has taste like this, and QI and blood biochemistry is active.
The unwilling even more oral drugs of the anorexia of children's own.And children's's skin is tender, visceral-qi is agile, and point-application effect is rapid, and to skin zero damage, therefore extensive in paediatric applications, especially in treatment children's digestive system disease, application is maximum.Acupuncture points on the human body be zang-fu differentiation QI and blood infusion in the privileged sites of body outside, be also the stimulation point of the method for the treatment of such as reflecting point and acupuncture of disease.Point application, is Chinese medicine is made ointment or medicine cake, is attached on selected acupuncture point, doing the existing stimulation to acupuncture point (being similar to acupuncture) like this, have again the osmosis of medicine, is one of method of inner disease outer treat.Back shu points is that qi of zang-fu viscera infusion is in the acupuncture points on the human body of back of the body waist.The back shu points that Pishu (bilateral), bl (bilateral) are taste.Pishu is at back, and when under eleventh dorsal vertebra spinous process, side opens 1.5 cun.Cure mainly indigestion and loss of appetite, dyspepsia, abdominal distention, have loose bowels.Bl is at back, and when under twelfth dorsal vertebra spinous process, side opens 1.5 cun.Cure mainly abdominal distention, indigestion and loss of appetite.SHENQUE acupoint is positioned at umbilicus, and at embryonic stage, umbilical part is that fetus is communicated with parent, obtains unique passage of blood, oxygen and nutrition supply.Though this passage is broken off after birth, umbilical part and whole body meridian, the vital organs of the human body still have very close relationship.Umbilicus is the place that stomach wall is the thinnest, does not have subcutaneous fat, but blood vessel is very abundant, so medicine is easy to infiltration, absorbs, adds medicine not by the hindering and damaging of gastric enzyme, therefore few, the instant effect of dosage.Multiple acupuncture point cooperatively interacts medication, can be multi-pronged, in the Shorten the Treatment Process cycle, reaches the object of rapid healing.
Detailed description of the invention
Embodiment
Treat a point-application Chinese medicine for infantile anorexia, be grouped into by the one-tenth of following mass fraction: Rhizoma Atractylodis Macrocephalae (parched) 3 parts, Fructus Amomi 2 parts, Fructus Amomi Rotundus 2 parts, Fructus Crataegi (parched to brown) 1 part, Fructus Hordei Germinatus (parched) 1 part, live chickens Endothelium corneum 1 part.
The preparation method of the point-application Chinese medicine of above-described treatment infantile anorexia, comprises the following steps:
(1), according to mass fraction, Rhizoma Atractylodis Macrocephalae (parched) 30g, Fructus Amomi 20g, Fructus Amomi Rotundus 20g, Fructus Crataegi (parched to brown) 10g, Fructus Hordei Germinatus (parched) 10g, live chickens Endothelium corneum 1g is taken;
(2), above-mentioned load weighted component is pulverized respectively after, cross 100 mesh sieve, obtain satisfactory powder;
(3), by after above-mentioned powder mixing and stirring, load in sealed container and preserve.
The using method of the point-application Chinese medicine of above-described treatment infantile anorexia, during use, gets medicine powder and is placed in clean container, after Rhizoma Zingiberis Recens juice furnishing pasty state, is made into the medicine cake of 2cm × 2cm, for subsequent use.
Allow infant to be treated get seat acupoint selection, partly sterilised, the medicine cake made is attached to Pishu (bilateral), bl (bilateral) and SHENQUE acupoint, cover with gauze, Breathable adhesive tape is fixed.General reservation 6-12 hours.Skin sensitivity person can shorten the time, and the good people of skin-tolerant can proper extension, but preferably no more than 24 hours, 7 days courses for the treatment of.
By some chronic disease of clinical eliminating, the infant as the reason of the apositia such as peptic ulcer, chronic hepatitis, tuberculosis, dyspepsia and prolonged constipation is divided into experimental group 40 example and matched group 36 example at random.2-6 years old experimental group ages, 2-6 years old matched group ages.Male 18 example in experimental group, women 22 example; Male 16 example in matched group, women 20 example, two groups of situations, without significant difference, have comparability.Experimental group uses and applies Qizhong medicine, and matched group adopts bacillus subtilis bigeminy enzyme alive one day twice once a bag.It within 7 days, is a course for the treatment of.Statistics t checks.Final result is as shown in the table:
Group Number of cases Cure Effective Effectively Invalid Total effective rate
Experimental group 40 22 13 5 0 100%
Matched group 36 2 3 26 5 86.2%
Two groups of differences have statistical significance (P<0.05)

Claims (2)

1. treat a point-application Chinese medicine for infantile anorexia, it is characterized in that: be grouped into by the one-tenth of following mass fraction: Rhizoma Atractylodis Macrocephalae (parched) 3 parts, Fructus Amomi 2 parts, Fructus Amomi Rotundus 2 parts, Fructus Crataegi (parched to brown) 1 part, Fructus Hordei Germinatus (parched) 1 part, live chickens Endothelium corneum 1 part.
2. the preparation method of the point-application Chinese medicine for the treatment of infantile anorexia according to claim 1, is characterized in that: comprise the following steps:
(1), according to mass fraction, Rhizoma Atractylodis Macrocephalae (parched) 3 parts, Fructus Amomi 2 parts, Fructus Amomi Rotundus 2 parts, Fructus Crataegi (parched to brown) 1 part, Fructus Hordei Germinatus (parched) 1 part, live chickens Endothelium corneum 1 part is taken;
(2), above-mentioned load weighted component is pulverized respectively after, cross 100 mesh sieve, obtain satisfactory powder;
(3), by after above-mentioned powder mixing and stirring, load in sealed container and preserve.
CN201310507162.XA 2013-10-24 2013-10-24 Point-application Chinese medicine for the treatment of infantile anorexia and preparation method thereof Expired - Fee Related CN103623327B (en)

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