CN103611155A - Australia tea tree effervescent tablet and preparation method thereof - Google Patents

Australia tea tree effervescent tablet and preparation method thereof Download PDF

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Publication number
CN103611155A
CN103611155A CN201310674293.7A CN201310674293A CN103611155A CN 103611155 A CN103611155 A CN 103611155A CN 201310674293 A CN201310674293 A CN 201310674293A CN 103611155 A CN103611155 A CN 103611155A
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CN
China
Prior art keywords
australia
preparation
camellia sinensis
effervescent tablet
tea tree
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Pending
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CN201310674293.7A
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Chinese (zh)
Inventor
刘守庆
李雪梅
毕荣璐
刘祥义
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Southwest Forestry University
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Southwest Forestry University
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Priority to CN201310674293.7A priority Critical patent/CN103611155A/en
Publication of CN103611155A publication Critical patent/CN103611155A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses an Australia tea tree effervescent tablet and a preparation method thereof. The preparation method comprises the steps of uniformly mixing superfine Australia tea tree powder, keratinase, organic acid, inorganic base and a lubricating agent according to an equivalent incremental method, and then, tabletting to prepare the Australia tea tree effervescent tablet. The effervescent tablet disclosed by the invention is convenient to use and free of any toxic and side effects and is only needed to be added into foot washing water when feet are washed; meanwhile, the Australia tea tree effervescent tablet can have the effects of killing pathogenic bacteria, diminishing inflammation and relieving pain, dissolving necrotic cuticles, rapidly relieving itching and integrating skin protection and skin maintenance.

Description

A kind of Australia Camellia sinensis effervescent tablet and preparation method thereof
Technical field
The present invention relates to field of medicaments, in particular a kind of Australia Camellia sinensis effervescent tablet and preparation method thereof.
Background technology
Australia Camellia sinensis is called again Melaleuca Alternifolia (Melaleuca ahemifolia), tea oil tree (Tea tree), it is that Myrtaceae (Myrtaceae), Melaleuca (Melaleuea1) evergreen shrubs are to dungarunga seeds, originate in Australian east, early 1990s starts to introduce China, at present in Guangxi, the ground such as Guangdong, Yunnan, Fujian all formed certain planting scale.Australia leaf of tea tree oil content reaches 2%, and content of total flavonol glycosides is more than 4%, and Australia tea tree oil main component is 4-terpineol, 1, 8-Cineole and terpinene.It can kill fungus and the antibacterial on human body skin surface efficient, nontoxic, non-stimulatedly, and some virus is also had to inhibitory action, its bactericidal effect is phenolic 11~13 times, Australia tea tree oil is one of best natural product of the health care found up to now and medical effect, is generally used abroad.
Beriberi is the popular name of tinea pedis, is in China, to belong to a class commonplace dermatosis of falling ill by fungal infection is caused, as treatment not in time, sometimes can infect to other position, as cause the tinea manuum and tinea unguium etc., sometimes because itch, be scratched, secondary antibacterial infects, and can cause serious complication.The reason of beriberi morbidity is mainly to be caused by Pathogen Infection, other skin erosion, blister, keratinization, the phenomenons such as pain of feeling to itch are all due to the subsidiary symptom after Pathogen Infection, and the preparation that therefore can rapidly and efficiently kill pathogenic microorganism is the good beriberic key factor for the treatment of.
Keratinase is the organized enzyme of a class energy hydrolysis of keratin, is applied at present cosmetics and skincare product, can help active factors to see through skin barrier, remove the unnecessary cutin of skin, realize the deep layer nursing of skin, reduce skin microgroove and wrinkle, keep skin moisturizing, increase skin consolidation and elasticity.
Summary of the invention
Technical problem to be solved by this invention is the deficiency existing in treatment beriberi for prior art, and a kind of Australia Camellia sinensis effervescent tablet and preparation method thereof is provided.
Technical scheme of the present invention is as follows:
A preparation method for Australia Camellia sinensis effervescent tablet, is by Australia Camellia sinensis superfine powder, keratinase, organic acid, inorganic base, lubricant, by equivalent incremental method mix homogeneously, takes 2-5g with 10-20kg pressure direct compression.
Described preparation method, calculates Australia Camellia sinensis superfine powder 40-60 part, keratinase 1-6 part, organic acid 5-20 part, inorganic base 5-20 part, lubricant 0-5 part by quality proportioning.
Described Australia Camellia sinensis superfine powder is with fresh Australia Camellia sinensis branch and leaf, dry rear first Ordinary pulverization, then make after micronizing, its granularity is 800-1500 order; Described organic acid is at least one in citric acid, tartaric acid or citric acid; Described inorganic base is at least one in sodium bicarbonate or sodium carbonate; Described lubricant is at least one in micropowder silica gel, magnesium stearate or Pulvis Talci.
Described preparation method makes Australia Camellia sinensis effervescent tablet.
Australia Camellia sinensis superfine powder of using in the present invention in different temperatures water (10-60 ℃) have good dissolubility, its effective ingredient can be dissolved out fast, tea tree oil and flavonoid glycoside have the very strong ability of killing to fungus, antibacterial etc.The present invention has selected keratinase, and tool, with well dissolving downright bad horny layer function, allows skin become smooth.Effervescent tablet of the present invention is easy to use, during foot bath, in foot-washing water, adds, without any side effects; Can reach simultaneously and kill pathogen, anti-inflammatory analgetic, the downright bad horny layer of dissolving, Quick itch stopping, skin protection and support the effect that skin is integrated.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is described in detail.
The preparation of embodiment 1 Australia Camellia sinensis effervescent tablet
Select Suo Chan Australia, Shuangbo County, Yunnan Province Camellia sinensis, it is 10-100 order that naturally shady dry Australia leaf of tea tree and sprout are crushed to granularity, then pulverizes to obtain 800-1500 object Australia Camellia sinensis superfine powder with low temperature supersonic jet mill.Supersonic jet mill condition used: temperature 30-60 ℃, pressure 0-0.5Pa, supersonic jet speed is 330-750 meter per second.
1, Australia Camellia sinensis superfine powder is 40 parts; 1 part of keratinase; 5 parts of citric acids; 8.2 parts of sodium bicarbonate; 2 parts of Pulvis Talci.
Preparation method: by Australia Camellia sinensis superfine powder and keratinase powder, equivalent increases progressively mix homogeneously; By remaining citric acid powder, sodium hydrogen carbonate powder, Pulvis Talci joins in Australia Camellia sinensis superfine powder and keratinase powder, after equivalent incremental method mix homogeneously, takes 3g with 10kg pressure direct compression.
2, Australia Camellia sinensis superfine powder is 50 parts; 2 parts of keratinase; 10 parts, tartaric acid; 14 parts of sodium bicarbonate; 4 parts of magnesium stearate.
Preparation method: by Australia Camellia sinensis superfine powder and keratinase powder, equivalent increases progressively mix homogeneously; By remaining tartaric acid powder, sodium hydrogen carbonate powder, magnesium stearate joins in Australia Camellia sinensis superfine powder and keratinase powder, after equivalent incremental method mix homogeneously, takes 5g with 15kg pressure direct compression.
3, Australia Camellia sinensis superfine powder is 60 parts; 3 parts of keratinase; 14 parts, tartaric acid; 16 parts of sodium carbonate; 4 parts of magnesium stearate.
Preparation method: by Australia Camellia sinensis superfine powder and keratinase powder, equivalent increases progressively mix homogeneously; By remaining tartaric acid powder, sodium carbonate powder, magnesium stearate joins in Australia Camellia sinensis superfine powder and keratinase powder, after equivalent incremental method mix homogeneously, takes 4g with 20kg pressure direct compression.
4, Australia Camellia sinensis superfine powder is 60 parts; 5 parts of keratinase; 19 parts of citric acids; 20 parts of sodium carbonate; 3 parts of micropowder silica gels.
Preparation method: Australia Camellia sinensis superfine powder is increased progressively and mixed homogeneously with keratinase powder equivalent; By remaining citric acid powder, sodium carbonate powder, micropowder silica gel joins in Australia Camellia sinensis superfine powder and keratinase powder, after equivalent incremental method mix homogeneously, takes 3g with 15kg pressure direct compression.
Embodiment 2 application examples
Liu, man, 53 years old, be diagnosed as keratinization type beriberi, skin is thick thick and dry, heel keratinization desquamation, scratch where it itches, chap, once used multiple Drug therapy, poor effect, use 3 of the effervescent tablets of preparation in the embodiment of the present invention 1, be placed in after basin foot bath 3 times, scratch where it itches and alleviate, heel is no longer peeled, and damages epidermis simultaneously and repairs to some extent.
Zhang, man, 45 years old, be diagnosed as fungi type beriberi, moist between the 4th and the 5th toe, dipping turns white, and odd itching, with multiple commercially available treatment beriberi unguentum treatment, outbreak repeatedly.Use 2 of the effervescent tablets of preparation in the embodiment of the present invention 1, be placed in after basin foot bath 5 times, now without itch and skin repair as usual.
Embodiment 3 clinical experiments
The present invention has the effect of the downright bad horny layer of anti-inflammatory analgetic, sterilization, dissolving, Quick itch stopping, reparation skin, simultaneously without any side effects, easy to use, during every day foot bath, in foot-washing water, adds.Light disease person takes effect for 1-2 time, cures for 5-7 time, and severe one takes effect for 4-6 time, cures for 15-20 time.Meanwhile, cure rear nothing recurrence.Clinical treatment 167 examples, effective 42 examples, effective 14 examples, cure 105 examples, total effective rate 96%.
Should be understood that, for those of ordinary skills, can be improved according to the above description or convert, and all these improvement and conversion all should belong to the protection domain of claims of the present invention.

Claims (4)

1. a preparation method for Australia Camellia sinensis effervescent tablet, is characterized in that, by Australia Camellia sinensis superfine powder, keratinase, organic acid, inorganic base, lubricant, by equivalent incremental method mix homogeneously, takes 2-5g with 10-20kg pressure direct compression.
2. preparation method according to claim 1, is characterized in that, calculates Australia Camellia sinensis superfine powder 40-60 part, keratinase 1-6 part, organic acid 5-20 part, inorganic base 5-20 part, lubricant 0-5 part by quality proportioning.
3. preparation method according to claim 1, is characterized in that, Australia Camellia sinensis superfine powder is with fresh Australia Camellia sinensis branch and leaf, dry rear first Ordinary pulverization, then make after micronizing, its granularity is 800-1500 order; Organic acid is at least one in citric acid, tartaric acid or citric acid; Inorganic base is at least one in sodium bicarbonate or sodium carbonate; Lubricant is at least one in micropowder silica gel, magnesium stearate or Pulvis Talci.
4. according to the arbitrary described preparation method of claim 1-3, make Australia Camellia sinensis effervescent tablet.
CN201310674293.7A 2013-12-11 2013-12-11 Australia tea tree effervescent tablet and preparation method thereof Pending CN103611155A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114451428A (en) * 2022-01-26 2022-05-10 昆明悦馨生物科技有限公司 Disinfection and sterilization effervescent tablet and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791333A (en) * 2010-01-13 2010-08-04 刘昭和 Medicine combination for treating dry tinea and application of medicine combination in preparation of medicine for treating dry tinea
CN101947313A (en) * 2010-08-30 2011-01-19 苏州邦安新材料科技有限公司 Novel effervescent tablet for treating beriberi and preparation process thereof
CN103159724A (en) * 2013-04-09 2013-06-19 云南森源化工有限公司 Method for simultaneously extracting australian tea tree flavone and beta-sitosterol

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791333A (en) * 2010-01-13 2010-08-04 刘昭和 Medicine combination for treating dry tinea and application of medicine combination in preparation of medicine for treating dry tinea
CN101947313A (en) * 2010-08-30 2011-01-19 苏州邦安新材料科技有限公司 Novel effervescent tablet for treating beriberi and preparation process thereof
CN103159724A (en) * 2013-04-09 2013-06-19 云南森源化工有限公司 Method for simultaneously extracting australian tea tree flavone and beta-sitosterol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114451428A (en) * 2022-01-26 2022-05-10 昆明悦馨生物科技有限公司 Disinfection and sterilization effervescent tablet and preparation method thereof

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Application publication date: 20140305