CN103610922B - 一种治疗小儿肺结核病的中药制剂 - Google Patents
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Abstract
本发明公开了一种治疗小儿肺结核病的中药制剂。肺结核是一种慢性传染病，属中医学“肺痨”范畴，病机要点为肺阴不足，脾胃亏虚，气血耗损，阴阳两虚。本发明本着扶正与祛邪兼顾的原则，选择具有滋阴清热，止咳化痰、健脾益肾的中药紫花芥、珍珠草、长距兰、九牛薯、苏合香、白菖、地血香果、南烛子、苤蓝、青羊参、狗爪豆、隔山消，水煎成汤剂，经临床试验，总有效率达到98.0％，疗效显著。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗小儿肺结核病的中药制剂。
背景技术
肺结核病是由于结核菌侵入人体肺脏引起肺部炎症反应及全身中毒症状的传染性疾病。临床多有发热、乏力、盗汗及咳嗽、咯痰等症状。肺结核的治疗，西医采用抗痨药物，疗效肯定。但抗痨药物一般疗程较长，且易产生耐药性。大量使用此类药物还会引起肝功能损害，胃肠不良反应、末梢血白细胞下降、神经系统兴奋性增高等副作用。中医治疗本病，扶正与祛邪兼顾，在治愈疾病的同时，能够改善虚弱状态，提高抗病能力。
发明内容
本发明的目的是提供一种治疗小儿肺结核病的中药制剂。肺结核是一种慢性传染病，在临床以逐渐消瘦，虚弱，伴咳嗽、咯血、潮热、盗汗为特征。属中医学“肺痨”范畴，古人又称为“痨瘵”、“肺疳”等。病机要点为肺阴不足，脾胃亏虚，气血耗损，阴阳两虚。病位主要在肺，累及脾、肾。本病的治疗应扶正与祛邪兼顾。治以滋阴清热，止咳化痰、健脾益肾。
本发明的目的是通过以下技术方案实现的，该治疗小儿肺结核病的中药制剂由以下重量份的中药制成：紫花芥5-15份、珍珠草20-30份、长距兰15-25份、九牛薯10-20份、苏合香0.3-1份、白菖5-10份、地血香果5-10份、南烛子12-16份、苤蓝25-30份、青羊参10-20份、狗爪豆30-40份、隔山消10-15份。
优选的，紫花芥10份、珍珠草25份、长距兰20份、九牛薯15份、苏合香0.5份、白菖7份、地血香果7份、南烛子14份、苤蓝27份、青羊参15份、狗爪豆35份、隔山消12份。
制备方法将上述中药水煎，制成汤剂。
方中：紫花芥祛痰定喘，泻肺行水；珍珠草平肝清热，利水解毒；长距兰、九牛薯润肺，止咳，祛痰；苏合香通窍辟秽，开郁豁痰；白菖化痰开窍，健脾利湿；地血香果强心补肾，止咳祛痰；南烛子补气益肾，益肾固精；苤蓝利水消肿，和脾；青羊参补肾镇痉，祛风湿；狗爪豆温中益气；隔山消养阴补虚，健脾消食。
临床资料
1、一般资料所选的本组患儿49例门诊病例经临床确诊为小儿肺结核病，年龄1～10岁，男性20例，女性29例。病程为2周～2个月，发热41例，体温高达38℃～39℃，有呼吸道症状者38例，其中单纯咳嗽咳痰21例，合并气促10例，合并喘息5例，合并发绀2例；有神经系统症状者11例，其中头痛8例次，抽搐5例次，性格改变3例次，意识障碍5例次；盗汗25例，合并消瘦12例；厌食31例，呕吐19例；其他症状有：腋下肿块1例，颈部肿块2例，骨骼疼痛1例。
2、诊断标准(1)临床表现：发热、咳嗽持续2周以上，或喘息等；(2)胸部X线检查：有各型肺结核的征象；(3)活动性结核病接触史；(4)结核菌素试验阳性；(5)痰液、胃液或支气管肺泡灌洗液结核杆菌涂片或培养阳性；(6)抗结核治疗有效；(7)除外肺部其他疾病，如各种原因的肺炎、肺肿瘤、肺囊肿、间质性肺疾病等；(8)肺组织病理检查符合肺结核特征。
3、治疗方法患儿服用本发明所述的中药制剂，称取紫花芥10g、珍珠草25g、长距兰20g、九牛薯15g、苏合香0.5g、白菖7g、地血香果7g、南烛子14g、苤蓝27g、青羊参15g、狗爪豆35g、隔山消12g。水煎取汁。3岁以下每次10ml，3～7岁每次20ml，7岁以上每次30ml。每日2次，于饭前30分钟温服，7日为一个疗程，连服4个疗程观察疗效。
4、疗效标准依据国家中医药管理局颁布的《中医病证诊断疗效标准》判断疗效。痊愈：全部症状及体征消失，异常理化检验指标恢复正常；有效：临床症状消失或明显减轻，异常理化指标接近正常；无效：临床症状无明显改变，异常理化指标无明显改善。
5、治疗结果本组患儿49例，其中临床痊愈27例(55.1％)，有效21例(42.9％)，无效1例(2％)，总有效率98.0％，疗效显著。
具体实施方式
实施例一：紫花芥10g、珍珠草25g、长距兰20g、九牛薯15g、苏合香0.5g、白菖7g、地血香果7g、南烛子14g、苤蓝27g、青羊参15g、狗爪豆35g、隔山消12g。制备方法：水煎取汁。
实施例二：紫花芥5g、珍珠草30g、长距兰15g、九牛薯20g、苏合香0.3g、白菖10g、地血香果5g、南烛子16g、苤蓝25g、青羊参20g、狗爪豆30g、隔山消15g。制备方法：水煎取汁。
实施例三：紫花芥15g、珍珠草20g、长距兰25g、九牛薯10g、苏合香1g、白菖5g、地血香果10g、南烛子12g、苤蓝30g、青羊参10g、狗爪豆40g、隔山消10g。制备方法：水煎取汁。
Claims (2)
1.一种治疗小儿肺结核病的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：紫花芥5-15份、珍珠草20-30份、长距兰15-25份、九牛薯10-20份、苏合香0.3-1份、白菖5-10份、地血香果5-10份、南烛子12-16份、苤蓝25-30份、青羊参10-20份、狗爪豆30-40份、隔山消10-15份。
2.根据权利要求1所述的一种治疗小儿肺结核病的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：紫花芥10份、珍珠草25份、长距兰20份、九牛薯15份、苏合香0.5份、白菖7份、地血香果7份、南烛子14份、苤蓝27份、青羊参15份、狗爪豆35份、隔山消12份。
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| CN1718062A (zh) * | 2005-07-25 | 2006-01-11 | 王浩贵 | 一种百部保健茶 |
| CN1907421A (zh) * | 2006-08-14 | 2007-02-07 | 陈积忠 | 防治肺病的中药鼻嗅粉剂 |
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| CN1718062A (zh) * | 2005-07-25 | 2006-01-11 | 王浩贵 | 一种百部保健茶 |
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