CN103609940A - Formula of chondroitin sulfate disaccharide containing food for patient suffering from myocarditis - Google Patents
Formula of chondroitin sulfate disaccharide containing food for patient suffering from myocarditis Download PDFInfo
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- CN103609940A CN103609940A CN201310596485.0A CN201310596485A CN103609940A CN 103609940 A CN103609940 A CN 103609940A CN 201310596485 A CN201310596485 A CN 201310596485A CN 103609940 A CN103609940 A CN 103609940A
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- Prior art keywords
- chondroitin sulfate
- myocarditis
- disaccharides
- vitamin
- patients
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- 229920001287 Chondroitin sulfate Polymers 0.000 title claims abstract description 32
- 229940059329 chondroitin sulfate Drugs 0.000 title claims abstract description 32
- -1 chondroitin sulfate disaccharide Chemical class 0.000 title claims abstract description 25
- 208000009525 Myocarditis Diseases 0.000 title claims abstract description 22
- 235000013305 food Nutrition 0.000 title claims abstract description 20
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 13
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 12
- 239000011707 mineral Substances 0.000 claims abstract description 12
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- 229930003231 vitamin Natural products 0.000 claims abstract description 12
- 235000013343 vitamin Nutrition 0.000 claims abstract description 12
- 239000011782 vitamin Substances 0.000 claims abstract description 12
- 235000013325 dietary fiber Nutrition 0.000 claims abstract description 10
- 229920002567 Chondroitin Polymers 0.000 claims description 11
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 11
- 239000002253 acid Substances 0.000 claims description 11
- 241000411851 herbal medicine Species 0.000 claims description 11
- 239000011593 sulfur Substances 0.000 claims description 11
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- 150000003722 vitamin derivatives Chemical class 0.000 claims description 11
- 230000006196 deacetylation Effects 0.000 claims description 3
- 238000003381 deacetylation reaction Methods 0.000 claims description 3
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- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 18
- 210000004165 myocardium Anatomy 0.000 description 5
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- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
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- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 2
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
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- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
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- 235000008599 Poria cocos Nutrition 0.000 description 2
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- 244000046146 Pueraria lobata Species 0.000 description 2
- 235000010575 Pueraria lobata Nutrition 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
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- 229930003471 Vitamin B2 Natural products 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 229930003316 Vitamin D Natural products 0.000 description 2
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 description 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- 229930003448 Vitamin K Natural products 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
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- 235000020958 biotin Nutrition 0.000 description 2
- 239000011616 biotin Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 2
- 229960001231 choline Drugs 0.000 description 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 229960002061 ergocalciferol Drugs 0.000 description 2
- 229960000304 folic acid Drugs 0.000 description 2
- 235000019152 folic acid Nutrition 0.000 description 2
- 239000011724 folic acid Substances 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000011630 iodine Substances 0.000 description 2
- 229910052740 iodine Inorganic materials 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
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- 230000001338 necrotic effect Effects 0.000 description 2
- 235000001968 nicotinic acid Nutrition 0.000 description 2
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- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
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- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 2
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- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 2
- 230000001732 thrombotic effect Effects 0.000 description 2
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- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 2
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- 239000011701 zinc Substances 0.000 description 2
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- 206010003211 Arteriosclerosis coronary artery Diseases 0.000 description 1
- 241000710188 Encephalomyocarditis virus Species 0.000 description 1
- 241000991587 Enterovirus C Species 0.000 description 1
- 241000175212 Herpesvirales Species 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
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- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
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- 239000007924 injection Substances 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
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- NHDHVHZZCFYRSB-UHFFFAOYSA-N pyriproxyfen Chemical compound C=1C=CC=NC=1OC(C)COC(C=C1)=CC=C1OC1=CC=CC=C1 NHDHVHZZCFYRSB-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pediatric Medicine (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a formula of a chondroitin sulfate disaccharide containing food for a patient suffering from myocarditis. The food is prepared by compounding chondroitin sulfate disaccharide, Chinese herbal extracts, chitosan oligosaccharide, chondrigen peptides, water-soluble dietary fiber, vitamins and mineral substances. According to the formula, the formation of thrombus can be delayed and resisted, and the state of an illness can be relieved.
Description
Technical field
The present invention relates to a kind of food formula, particularly a kind of food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis.
Background technology
Myocarditis is to cause one group of disease, its minute infectivity, rheumatic, allergy and the allergy of heart change and the myocarditis that chemical factors causes by different pathogeny, but most myocarditis is caused by virus clinically.Vital myocarditis refers to has a liking for that disposition virus infections causes, the non-specific interstitial inflammation of the cardiac muscle of take is main pathology.Confirmed at present to cause that myocarditic virus comprises: picornavirus as the COxsackie of enteron aisle, dust can, poliovirus, arboviruse, influenza virus, paramyxovirus, rubella virus, herpesviral, adenovirus, reovirus, encephalomyocarditis virus etc.In recent years, the myocarditic incidence of disease has the trend of increasing year by year, has become the common disease of harm health of people, aspect myocarditic antiviral therapy and raising immune function of human body, traditional Chinese medicine has one's own knack, and utilizes traditional Chinese medicine prevention myocarditis to have clinically good curative effect.By the edible chondroitin sulfate disaccharides that myocarditis is had to special treatment effect, more auxiliary edible traditional Chinese medicine ingredients, can have certain preventive and therapeutic action to myocarditis.
But because chondroitin sulfate molecular weight is larger, hydrophilic group is many, fat-soluble poor, therefore absorb not exclusively in body, the deficiency that bioavilability is low is also perplexing the large-scale application of chondroitin sulfate similar drug always.
And chondroitin sulfate disaccharides obtains by the chondrosulphatase chondroitin sulfate of degrading, relatively common chondroitin sulfate, because molecular weight reduces, be more conducive to by body, absorbed and utilize, at aspects such as medicinal, health products and cosmetics, have huge application potential.
Summary of the invention
For above-mentioned defect and the problem of prior art, the object of the embodiment of the present invention is to provide the formation that can delay thrombus, is improved the state of an illness, resists the thrombotic food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis.
Based on above-mentioned purpose, the invention provides following technical scheme:
A food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis, comprises that chondroitin sulfate disaccharides, Chinese herbal medicine extract, chitosan oligosaccharide, chondrigen peptide, water-soluble dietary fiber, vitamin and mineral matter are composited.
Preferably, in 100g food formula, chondroitin sulfate disaccharides content is at 50-70g, and Chinese herbal medicine extract is 5-10g, chitosan oligosaccharide 3-5g, chondrigen peptide 10-15g, water-soluble dietary fiber 2-4g, vitamin 200-400mg, mineral matter 2-3g.
Preferably, Chinese herbal medicine extract is Chinese yam, spina date seed, the root of kudzu vine, the fruit of Chinese wolfberry, sealwort, mulberry leaf, Poria cocos, cape jasmine, fructus amomi, Radix Glycyrrhizae and Semen sesami nigrum etc.
Preferably, vitamin is a kind of, several or all mixing in vitamin A, vitamin B1, vitamin B2, vitamin B6, cobalamin, vitamin C, vitamin D, vitamin E, vitamin K, nicotinic acid, folic acid, pantothenic acid, choline and biotin.
Preferably, mineral matter is a kind of, several or all mixing in calcium, phosphorus, potassium, sodium, magnesium, iron, zinc, selenium, iodine.
Preferably, the molecular weight of described chitosan oligosaccharide is below 2000, and the degree of polymerization is between 2-12, and deacetylation is more than 95%.
Preferably, described chondrigen peptide divides in amount below 1500Da, and protein content is more than 98%.
The invention has the beneficial effects as follows: by above-mentioned formula, make food and can effectively prevent the damage coronarius being caused by excessive calciferol and cholesterol, chondroitin sulfate has antiinflammatory action, especially for myocarditis, myocardium pathology and necrosis etc.Chondroitin sulfate can promote reparation, healing and the regeneration of the necrotic myocardium that heart stalk causes.
The specific embodiment
Below in conjunction with embodiments of the invention, technical scheme of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
A food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis, comprises that chondroitin sulfate disaccharides, Chinese herbal medicine extract, chitosan oligosaccharide, chondrigen peptide, water-soluble dietary fiber, vitamin and mineral matter are composited.
embodiment 1
In 100g food formula, chondroitin sulfate disaccharides content is at 65g, and Chinese herbal medicine extract is 10g, chitosan oligosaccharide 5g, chondrigen peptide 15g, water-soluble dietary fiber 2.8g, vitamin 200mg, mineral matter 2g.
embodiment 2
In 100g food formula, chondroitin sulfate disaccharides content is at 70g, and Chinese herbal medicine extract is 5g, chitosan oligosaccharide 4g, chondrigen peptide 14g, water-soluble dietary fiber 3.7g, vitamin 300mg, mineral matter 3g.
Preferred technical scheme, Chinese herbal medicine extract is Chinese yam, spina date seed, the root of kudzu vine, the fruit of Chinese wolfberry, sealwort, mulberry leaf, Poria cocos, cape jasmine, fructus amomi, Radix Glycyrrhizae and Semen sesami nigrum etc.
Preferred technical scheme, vitamin is a kind of, several or all mixing in vitamin A, vitamin B1, vitamin B2, vitamin B6, cobalamin, vitamin C, vitamin D, vitamin E, vitamin K, nicotinic acid, folic acid, pantothenic acid, choline and biotin.
Preferred technical scheme, mineral matter is a kind of, several or all mixing in calcium, phosphorus, potassium, sodium, magnesium, iron, zinc, selenium, iodine.
Preferred technical scheme, the molecular weight of described chitosan oligosaccharide is below 2000, and the degree of polymerization is between 2-12, and deacetylation is more than 95%.
Preferred technical scheme, described chondrigen peptide divides in amount below 1500Da, and protein content is more than 98%.
Chondroitin sulfate can effectively be alleviated incidence and the deposition degree of coronary artery lipidosis, and his chondroitin sulfate A (CSA) can effectively prevent the damage coronarius being caused by excessive calciferol and cholesterol in addition.1966, the every days such as Morrison, discovery chondroitin sulfate can effectively be alleviated atherosclerotic symptom, reduces this disease incidence to Squirrel monkey hypodermic injection chondroitin sulfate.Rear Morrison etc. are to Squirrel monkey intramuscular injection chondroitin sulfate A (CSA), and the Squirrel monkey heart base portion that applies chondroitin sulfate is observed in experiment does not have coronary atherosclerosis completely.Japanese scholars Nakazawa, by Coronary Heart Disease Patients intravenous injection chondroitin sulfate, finds that chondroitin sulfate can delay the formation of thrombus, is improved the state of an illness, resists thrombotic effect.Morrison studies by Long-term clinical experimental observation, show that chondroitin sulfate has obvious curative effect to miocardial infarction, myocardial infarction, coronary artery disease, angina pectoris etc.At clinical experimental stage, without abnormal conditions, occur, tentatively conclude that chondroitin sulfate has no side effect.In addition, multinomial achievement in research shows, chondroitin sulfate has antiinflammatory action, especially for myocarditis, myocardium pathology and downright bad etc.Chondroitin sulfate can promote reparation, healing and the regeneration of the necrotic myocardium that heart stalk causes.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited to this, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; can expect easily changing or replacing, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion by the described protection domain with claim.
Claims (6)
1. for a food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis, it is characterized in that, comprise that chondroitin sulfate disaccharides, Chinese herbal medicine extract, chitosan oligosaccharide, chondrigen peptide, water-soluble dietary fiber, vitamin and mineral matter are composited.
2. confession patients with myocarditis according to claim 1 eats the food formula of sulfur acid chondroitin disaccharides, it is characterized in that, in 100g food formula, chondroitin sulfate disaccharides content is at 50-70g, and Chinese herbal medicine extract is 5-10g, chitosan oligosaccharide 3-5g, chondrigen peptide 10-15g, water-soluble dietary fiber 2-4g, vitamin 200-400mg, mineral matter 2-3g.
3. confession patients with myocarditis according to claim 1 eats the food formula of sulfur acid chondroitin disaccharides, it is characterized in that, chondroitin sulfate disaccharides content is at 65g, Chinese herbal medicine extract is 10g, chitosan oligosaccharide 5g, chondrigen peptide 15g, water-soluble dietary fiber 2.8g, vitamin 200mg, mineral matter 2g.
4. confession patients with myocarditis according to claim 1 eats the food formula of sulfur acid chondroitin disaccharides, it is characterized in that, chondroitin sulfate disaccharides content is at 70g, Chinese herbal medicine extract is 5g, chitosan oligosaccharide 4g, chondrigen peptide 14g, water-soluble dietary fiber 3.7g, vitamin 300mg, mineral matter 3g.
5. kind prepare the food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis as claimed in claim 1 or 2, it is characterized in that, the molecular weight of described chitosan oligosaccharide is below 2000, and the degree of polymerization is between 2-12, and deacetylation is more than 95%.
6. the food formula for the edible sulfur acid chondroitin disaccharides of patients with myocarditis according to claim 1 and 2, is characterized in that, described chondrigen peptide divides in amount below 1500Da, and protein content is more than 98%.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105815627A (en) * | 2015-01-08 | 2016-08-03 | 青岛农业大学 | Method for producing food containing peanut peptide used for special meal for patients with hepatopathy |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2106798A1 (en) * | 2008-04-02 | 2009-10-07 | Nestec S.A. | Sulfated unsaturated disaccharidic chondroitin sulfate in connective tissue protection and repair |
| CN102150836A (en) * | 2010-12-23 | 2011-08-17 | 烟台理博天然药物开发有限公司 | Ammonia sugar peptide soft capsule |
| CN102671191A (en) * | 2012-03-28 | 2012-09-19 | 孙天民 | Composition with high dose of chondroitin sulfuric acid and method for treating type 2 diabetes mellitus |
-
2013
- 2013-11-21 CN CN201310596485.0A patent/CN103609940A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2106798A1 (en) * | 2008-04-02 | 2009-10-07 | Nestec S.A. | Sulfated unsaturated disaccharidic chondroitin sulfate in connective tissue protection and repair |
| CN102150836A (en) * | 2010-12-23 | 2011-08-17 | 烟台理博天然药物开发有限公司 | Ammonia sugar peptide soft capsule |
| CN102671191A (en) * | 2012-03-28 | 2012-09-19 | 孙天民 | Composition with high dose of chondroitin sulfuric acid and method for treating type 2 diabetes mellitus |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105815627A (en) * | 2015-01-08 | 2016-08-03 | 青岛农业大学 | Method for producing food containing peanut peptide used for special meal for patients with hepatopathy |
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Application publication date: 20140305 Assignee: Qingdao Belt Marine Technology Co., Ltd. Assignor: Better (Qingdao) Biological Technology Co., Ltd. Contract record no.: 2014370000175 Denomination of invention: Formula of chondroitin sulfate disaccharide containing food for patient suffering from myocarditis License type: Common License Record date: 20141208 |
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