CN103599372B

CN103599372B - Medicine for treating shiver after intravertebral anesthesia

Info

Publication number: CN103599372B
Application number: CN201310590302.4A
Authority: CN
Inventors: 王德俊
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-11-19
Filing date: 2013-11-19
Publication date: 2015-03-18
Anticipated expiration: 2033-11-19
Also published as: CN103599372A

Abstract

The invention relates to a medicine for treating shiver after intravertebral anesthesia. The medicine is prepared from the following substances in parts by weight: 6 parts of ligustrum sinense, 8 parts of Chinese clovershrub root, 3 parts of chuihuotong (Chinese character), 6 parts of diospyros lotus, 5 parts of rhizome drynariae, 7 parts of willowweed, 6 parts of aerides falcata and 8 parts of rauvolfia verticillata. The medicine for treating the shiver after intravertebral anesthesia disclosed by the invention has the characteristics of being low in cost, easy to prepare, small in toxic and side effects, and significant in curative effect.

Description

A kind of treat intravertebral anesthesia after the medicament of shivering with cold

Technical field

The present invention relates to Anesthesia Department field, specifically, relate to a kind of treat intravertebral anesthesia after the medicament of shivering with cold.

Background technology

Intravertebral anesthesia is clinical conventional anaesthesia technology, and after anesthesia, shiver with cold is its common complication.Shiver with cold body oxygen consumption not only can be made to increase, height fear can make patient occur agitation, restless and impact operation operation.Therefore, in the urgent need to find a kind of treat intravertebral anesthesia after the medicament of shivering with cold.

Summary of the invention

The object of this invention is to provide a kind of treat intravertebral anesthesia after the medicament of shivering with cold.

In order to realize object of the present invention, the invention provides a kind of treat intravertebral anesthesia after the medicament of shivering with cold, it is made up of the material of following weight proportioning: ligustrum sinense 6 parts, Radix Campylotropis Macrocarpae 8 parts, Ramulus Et folium Spiraeae Acuminatae 3 parts, circuitous sub 6 parts of monarch, rock Rhizoma Zingiberis Recens 75 parts, LIUYECAI 7 parts, fingernail blue 6 parts and Rauvolfia verticillata 8 parts.

Preferably, medicament of the present invention is tablet, buccal tablet, rapidly dissolving tablet or decoction.

In order to understand the present invention better, with reference to " Chinese medicine voluminous dictionary " second edition, being described as follows of some crude drug used in the present invention:

[different name] water Ilicis Purpureae, fish are cured, fish La Shu (" Zhiwu Mingshi Tukao "), water-white cured (" Chinese herbal medicine is commonly used in Sichuan "), Ilicis Purpureae (" national Chinese herbal medicine new therapy that combines both Chinese and Western medical practices exhibition material a collection of selected materials "), Ligustrum sinense, Rheum alexandrae Batal. poplar (" Xinhua's book on Chinese herbal medicine outline ").

The bark that [base is former] is the little wax of Oleaceae Ligustrum plant and branch and leaf.

[different name] artificial flower raw (" Medicinal Plants of Guangxi register "), the horse material tip (" Tian Mu Shan Mountain medicinal plants will ").

[base is former] is pulse family sub-tip platymiscium the root of the sub-tip or branch and leaf.

[former plant] sub-tip Campylotropis macrocarpa (Bunge) Rehd. [Lespedeza macrocarpa Bunge]

[different name] thousand rice (" Yunnan Chinese herbal medicine ").

[base is former] is the Herb of the narrow leaf Ramulus et Folium Spiraeae Salicifolia of Rosaceae Spiraea.

[former plant] narrow leaf Ramulus et Folium Spiraeae Salicifolia spiraea japomicaL.f. var.acu minata Franch. has another name called: sharp leaf Ramulus et Folium Spiraeae Salicifolia.

Fructus Dispyroris Loti

[base is former] is the fruit of Ebenaceae Diospyros plant Fructus Dispyroris Loti.

[former plant] Fructus Dispyroris Loti Diospyros lotus L.

[different name] Setaria palmifolia (" Zhiwu Mingshi Tukao "), climbing the mountain, Rhizoma Zingiberis Recens, knochenbruch are sticky, careless, the large Herba Lepisori Thunbergiani Microsorium membranaceum (Don) Ching. of double-edged sword (" Medicinal Plants in Yunnan register "), Herba Pyrrosiae Calvatae, Colysis henryi (Bak.) Ching (" Xichang Chinese herbal medicine "), chicken foot lotus (" Traditional Chinese Medicine in Sichuan will "), great Ye bag pin (" Medicinal Plants of Guangxi register ").

[base is former] is the herb of fire hose back of the body science-star Cyclosorus plant Microsorium membranaceum (Don) Ching. band rhizome.

[former plant] Microsorium membranaceum (Don) Ching. Microsorium membranaceum (Don) Ching [Polypodium membranaceum Don]

[different name] Herba Ludwigiae Prostratae, Aleuritopteris argentea (Gmel.) Fee, water Cymbidium ensifolium (L.) Sw. (" choosing of Yunnan Chinese herbal medicine "), Herba Epilobii Hirsuti, Radix Euphorbiae Cortex torricelliae tiliifoliae (" Shaanxi Chinese herbal medicine "), water synthetism, stepmother's pregnant (" Xichang Chinese herbal medicine "), the pale reddish brown grass of floss rod, long hornwart, bright grass (" national Chinese herbal medicine compilation "), little willow (" Guizhou Chinese herbal medicine register "), key cylinder (" Medicinal Plants of Guangxi register ").

[base is former] is the herb of Oenotheraceae Epilobium plant LIUYECAI.

[former plant] LIUYECAI Epilobium hirsutum L. has another name called: blunt leaf LIUYECAI, western LIUYECAI (" Xinhua's book on Chinese herbal medicine outline ").

[base is former] is the herb of the orchid family Calanthe plant short stem calyx ridge orchid.

Blue Sedirea subparishii (Tsi) E.A.Chr. [Hygrochilus subparishii Tsi] of [former plant] short stem calyx ridge has another name called: celestial being Hua Lan (" zhejiang plants will ").

[different name] tripod is caught up with (" Hainan flora "), three fork hardships (" Fujian Chinese herbal medicine "), three fork tigers (" south of the Five Ridges herbal ").

The stem that [base is former] is Rutaceae Haozhuyu platymiscium Foliumet Ramulus Evodiae, leaf or root.

[former plant] Foliumet Ramulus Evodiae Evodia lepta (Spereng.) Merr. [ilea lepta Spreng.] has another name called: cushat flower (" Chinese Higher plant illustrated handbook ").

The medicament of shivering with cold after treatment intravertebral anesthesia of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect shows.

Detailed description of the invention

Embodiment 1: the preparation of decoction of the present invention

Claim ligustrum sinense 6 grams, Radix Campylotropis Macrocarpae 8 grams, Ramulus Et folium Spiraeae Acuminatae 3 grams, circuitous sub 6 grams of monarch, rock Rhizoma Zingiberis Recens 75 grams, LIUYECAI 7 grams, fingernail blue 6 grams and Rauvolfia verticillata 8 grams, add 6000 milliliters, water, be placed in the flask of sealing, heat 4 hours under the water-bath of 90 DEG C, filter, filtrate is decoction of the present invention.

Experimental example

50 routine epidural anesthesia shiver with cold persons are all lower limb, lower abdomen, spinal column art, ASA I-II level, wherein man 25 example, female 25 example, 38 ± 3 years old age, body weight 56 ± 6kg.Preoperative all non-medication, operating room temperature controls at 22 DEG C-25 DEG C, and in art, transfusion is the liquid in room temperature environment.Get T ₁₁-L ₄, head-end puts pipe 3 centimetres, and test dose injects 2 volume % lignocaine 5 milliliters.Without uncomfortable after 5 minutes, add 2 volume % lignocaine 7-15ml, level of anesthesia reaches requirements of operation.Conventional oxygen supply after anesthesia, monitors HR, NBP, ECG, SPO in art ₂.Patient's readme is afraid of cold and is had face and limb muscle independently not to tremble for shiver with cold case.50 example shiver with cold cases are divided into treatment group and matched group, and often group is 25 examples, and the age of two groups of patients, body weight, local anaesthetics consumption, operating time there are no significant difference (P>0.05), have comparability.

There is the decoction 50 milliliters of oral embodiment 1 preparation in latter 2 minutes in shiver with cold in treatment group, each 4 hours once oral, continuous oral 3 times.There is latter 2 minutes angular vein injecting normal salines 5 milliliters in matched group in shiver with cold.The shiver with cold situation of two groups of patients is observed after 12 hours.

Criterion of therapeutical effect

Effective: patient's fear of cold and shiver with cold disappear; Take a turn for the better: have fear of cold but without shiver with cold; Invalid: to still have fear of cold and shiver with cold.Effective+improvement person is considered as effectively.

Therapeutic outcome

Effective 17 examples for the treatment of group, take a turn for the better 6 examples, and effective percentage is 92.0%, and apparently higher than matched group, difference has significance (P<0.01), in table 1.

Table 1 liang group comparitive study (example)

Safety analysis

Do not occur serious adverse reaction in observation, treatment terminates the blood of rear treatment group patient, urine, stool routine and hepatic and renal function inspection and is showed no exception.

Claims

1. a medicament of shivering with cold after treating intravertebral anesthesia, is characterized in that it is made up of the material of following weight proportioning: ligustrum sinense 6 parts, Radix Campylotropis Macrocarpae 8 parts, Ramulus Et folium Spiraeae Acuminatae 3 parts, Fructus Dispyroris Loti 6 parts, rock Rhizoma Zingiberis Recens 75 parts, LIUYECAI 7 parts, fingernail blue 6 parts and Rauvolfia verticillata 8 parts.