CN103585468A - 一种治疗书写痉挛症的中药及其制备方法 - Google Patents
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Abstract
本发明涉及一种治疗书写痉挛症的中药及其制备方法，由以下重量配比的药材制备而成：芡实12份、腰子草9份、香橼6份、蚯蚓8份、芡实茎6份、岩谷伞5份。实验证明，本发明能够安全有效治疗书写痉挛症。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗书写痉挛症的中药及其制备方法。
背景技术
书写痉挛症是由于职业因素长期从事手部精细动作，从而导致手部肌肉痉挛，出现以书写功能障碍为主的一种症状群，属于职业性共济神经功能性疾病。该病好发于中青年，确切的病因尚不明了，估计与大脑基底节细胞的退行性变化有一定关系，与精神因素（紧张、恐惧等）关系较密切。主要表现，手指不灵活、不协调，手部肌肉出现痉挛性收缩或双手颤动，持笔难、写字歪斜等。书写痉挛艰症患者思维敏捷，面无偏瘫，无肌肉萎缩，反射正常，脑部CT检查也无异常，故易与神经系统疾病鉴别。
中医认为本病自虚型体质和诱发因素两端合为一端而起病。前者由于精、气、神素亏，肾主精，精亏则肾伤，肾伤及肝，筋脉则易舒缩失常；肺主气，气生于精，气伤又由于无生生之源，肺气、宗气益乏鼓动和斡旋之力；心脑主神藏神，神伤则心脑想通之路碍于交接，而神失灵动之机，非即时发病，抑即埋下起病的伏因。后者是发病的重要因素，一有情绪激动，或惊或恐，必致本病发生，并可延绵，久治不愈。
本发明中药所涉及药材的研究现状如下：
芡实：【来源】本品为睡莲科植物芡Euryale ferox Salisb. 的干燥成熟种仁。【功能主治】益肾固精，补脾止泻，祛湿止带。用于梦遗滑精，遗尿尿频，脾虚久泻，白浊，带下。
腰子草：【来源】药材基源：为兰科植物蛇尾草的块根及全草。【性味】味甘；性温。【功能主治】益肾壮阳；养血补虚；理气除湿。主虚劳；眼目昏花；阳痿；遗精；睾丸肿痛；白浊；白带。
香橼：【来源】本品为芸香科植物枸橼Citrus medica L.或香圆（西南香圆）Citrus wilsonii Tanaka的干燥成熟果实。【功能主治】舒肝理气，宽中，化痰。用于肝胃气滞，胸胁胀痛，脘腹痞满，呕吐噫气，痰多咳嗽。
蚯蚓：【来源】为巨蚓科动物参环毛蚓或正蚓科动物背暗异唇蚓等的全体。【功能主治】清热，平肝，止喘，通络。治高热狂躁，惊风抽搐，风热头痛，目赤，中风半身不遂，喘息，喉痹，关节疼痛，齿衄，小便不通，瘰疬。痄腮，疮疡。
芡实茎：【来源】为睡莲科植物芡的花茎。【性味】《纲目》："咸甘，平，无毒。"【功能主治】《纲目》："止烦渴，除虚热，生熟皆宜。"
岩谷伞：【来源】为真藓科植物暖地大叶藓的全草。夏秋采收。【性味】辛《云南中草药》："辛苦，平。"【功能主治】镇静安神，清心明目。治心脏病，神经衰弱，阳痿。
发明内容
本发明旨在提供一种治疗书写痉挛症的中药及其制备方法，通过选择合适的药材及其配比，达到安全有效治愈书写痉挛症的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗书写痉挛症的中药，其特征在于，由以下重量配比的药材制备而成：芡实12份、腰子草9份、香橼6份、蚯蚓8份、芡实茎6份、岩谷伞5份。
所述的治疗焦虑症的中药的制备方法，其特征在于，按照以下步骤制备而成：称取所述药材，加入药材总重8倍量的水，煎煮1.5小时，过滤；滤渣再加入药材总重6倍量的水，煎煮1小时，过滤；合并两次过滤所得滤液，浓缩，干燥成粉状，装入胶囊壳，即得。
下面结合中医理论说明本发明的有益效果：
发明人认为，因气为神之主，神生于气，精为身之本，气生于精，而精为肾之主，精气神俱伤，故首先要补肾；由于肾伤或惊恐伤肾，肾累及肝，筋脉失却任持而手颤，颤或痉皆风之象，风淫末疾，故治本症既要补肾又要熄风。本发明运用：芡实、腰子草益肾固精；香橼、蚯蚓疏肝理气；芡实茎、岩谷伞镇静安神。诸药合用，从根本上调理患者的病症。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年6月-2010年9月间共收集82例确诊书写痉挛症的门诊患者，其中男42例、女40例，年龄15-34岁，病程1-3年。随机分为：治疗组50例，空白组32例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程7天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程7天。
2.3观察项目：治疗前后手指不灵活、不协调，手部肌肉出现痉挛性收缩或双手颤动，持笔难、写字歪斜等症状。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) | 不良反应例 |
| 治疗组 | 50 | 38(76%) | 10 | 2 | 96% | 0 |
| 空白组 | 32 | 0（0%） | 8 | 24 | 25% | 0 |
相比空白组，治疗组的痊愈率和总有效率均有非常显著性差异（p<0.01）。可见，本发明制得的药物能够安全有效治书写痉挛症。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
实施例1
称取：芡实12克、腰子草9克、香橼6克、蚯蚓8克、芡实茎6克、岩谷伞5克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗书写痉挛症。口服，每日分早晚两次服用。
实施例2
称取：芡实12克、腰子草9克、香橼6克、蚯蚓8克、芡实茎6克、岩谷伞5克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗书写痉挛症。口服，每日分早晚两次服用。
实施例3
称取：芡实12克、腰子草9克、香橼6克、蚯蚓8克、芡实茎6克、岩谷伞5克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗书写痉挛症。口服，每日分早晚两次服用。
Claims (2)
1.一种治疗书写痉挛症的中药，其特征在于，由以下重量配比的药材制备而成：芡实12份、腰子草9份、香橼6份、蚯蚓8份、芡实茎6份、岩谷伞5份。
2.如权利要求1所述的治疗焦虑症的中药的制备方法，其特征在于，按照以下步骤制备而成：称取所述药材，加入药材总重8倍量的水，煎煮1.5小时，过滤；滤渣再加入药材总重6倍量的水，煎煮1小时，过滤；合并两次过滤所得滤液，浓缩，干燥成粉状，装入胶囊壳，即得。
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1294006A (zh) * | 1999-10-28 | 2001-05-09 | 李仕元 | 一种治疗中风后遗症药物的制备方法 |
| CN1739770A (zh) * | 2005-08-25 | 2006-03-01 | 贺拴友 | 一种治疗抑郁症、神经症的中药组合物 |
| CN102366601A (zh) * | 2011-10-20 | 2012-03-07 | 邓华伦 | 治中风口眼歪斜半身不遂的中药制剂 |
| CN102940761A (zh) * | 2012-11-08 | 2013-02-27 | 梁立祥 | 一种治疗书写痉挛症的中药 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1294006A (zh) * | 1999-10-28 | 2001-05-09 | 李仕元 | 一种治疗中风后遗症药物的制备方法 |
| CN1739770A (zh) * | 2005-08-25 | 2006-03-01 | 贺拴友 | 一种治疗抑郁症、神经症的中药组合物 |
| CN102366601A (zh) * | 2011-10-20 | 2012-03-07 | 邓华伦 | 治中风口眼歪斜半身不遂的中药制剂 |
| CN102940761A (zh) * | 2012-11-08 | 2013-02-27 | 梁立祥 | 一种治疗书写痉挛症的中药 |
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