CN103583564B - A kind of efficient bactericidal composite containing simeconazoles and triazole type - Google Patents
A kind of efficient bactericidal composite containing simeconazoles and triazole type Download PDFInfo
- Publication number
- CN103583564B CN103583564B CN201210294511.XA CN201210294511A CN103583564B CN 103583564 B CN103583564 B CN 103583564B CN 201210294511 A CN201210294511 A CN 201210294511A CN 103583564 B CN103583564 B CN 103583564B
- Authority
- CN
- China
- Prior art keywords
- simeconazoles
- active component
- active
- test
- triazole type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention discloses a kind of efficient bactericidal composite containing simeconazoles and triazole type, bactericidal composition containing active components A and active component B, active components A is selected from simeconazoles, active component B is triazole bactericidal agent, described triazole bactericidal agent is selected from any one compound following: Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, Flutriafol, and the weight ratio of active components A and active component B is 1 ︰ 70 ~ 70 ︰ 1.The present composition has greater activity to the multiple diseases in various crop, and has obvious synergistic effect, expands fungicidal spectrum.And have that dosage is little, resistance of rainwater washing against, the obvious feature of synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of efficient bactericidal composite in crop pest containing simeconazoles and triazole type.
Technical background
Simeconazoles (simeconazole), molecular formula: C
14h
20fN
3oSi, chemical name: (RS)-2-(4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-(is trimethyl silicon based) propan-2-ol, simeconazoles is sterol demethylation inhibitors, the biosynthesis of the cell membrane important composition composition ergosterol of destruction and prevention germ, causes cell membrane not formed, and makes germ dead.Owing to having absorption well, therefore can promptly be absorbed by plants, and in conducted inside; There is well protection and therapeutic activity.Significantly improve crop yield.
Triazole bactericidal agent broad-spectrum-have very high activity to the many kinds of disease funguses of sac fungi, basidiomycetes, imperfect fungus, but to oomycetes non-activity; Efficiently-drug effect is high, dosage reduces; Lasting period length-blade face 15-20 days, seed treatment about 80 days, soil treatment 100 days, all long than general bactericide, and extend with the increase of dosage; Uptake and transmission is good, and infiltration rate is fast, dispenser after 2 hours the absorbed amount of triazolone can suppress the growth of powdery mildew; There is strong preventive effect, good therapeutic action, stifling and eradicant action.The mechanism of action, for affect sterols biosynthesis, makes somatic cells film function be damaged.
In the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find simeconazoles and Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, Flutriafol mutually composite, there is good synergistic effect within the specific limits, and about simeconazoles and Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, Flutriafol relevant composite, there is not yet relevant report at home and abroad at present.
Summary of the invention
The object of the invention is to propose a kind ofly have that synergistic function, use cost are low, preventive effect is good containing the efficient bactericidal composite of simeconazoles and triazole type.
The present invention is achieved through the following technical solutions:
A kind of efficient bactericidal composite containing simeconazoles and triazole type, it is characterized in that containing active components A and active component B, active components A and active component B weight ratio are 1 ︰ 70 ~ 70 ︰ 1, described active components A is selected from simeconazoles, active component B is triazole bactericidal agent, and described triazole bactericidal agent is selected from any one compound following: the one in Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, Flutriafol; The preferred weight ratio of active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1; The weight ratio being more preferably simeconazoles and Tebuconazole is 1 ︰ 30 ~ 30 ︰ 1; The weight ratio of simeconazoles and own azoles alcohol is 1 ︰ 20 ~ 30 ︰ 1; The weight ratio of simeconazoles and Difenoconazole is 1 ︰ 30 ~ 30 ︰ 1; The weight ratio of simeconazoles and penconazole is 1 ︰ 10 ~ 20 ︰ 1; The weight ratio of simeconazoles and propiconazole is the weight ratio of 1 ︰ 20 ~ 10 ︰ 1, simeconazoles and Flutriafol is 1 ︰ 30 ~ 30 ︰ 1, and the weight ratio most preferably being simeconazoles and Tebuconazole is 1 ︰ 10 ~ 10 ︰ 1; The weight ratio of simeconazoles and own azoles alcohol is 1 ︰ 10 ~ 10 ︰ 1; The weight ratio of simeconazoles and Difenoconazole is 1 ︰ 10 ~ 10 ︰ 1; The weight ratio of simeconazoles and penconazole is 1 ︰ 4 ~ 8 ︰ 1; The weight ratio of simeconazoles and propiconazole is the weight ratio of 1 ︰ 10 ~ 2 ︰ 1, simeconazoles and Flutriafol is 1 ︰ 10 ~ 10 ︰ 1.
The described efficient bactericidal composite containing simeconazoles and triazole type is for preventing and treating the disease of crop, and described crop comprises cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop.
Described disease comprises downy mildew, late blight, early blight, phytophthora root rot, damping off, mottled rot disease, powdery mildew, banded sclerotial blight, rice blast, false smut, leaf spot, spot defoliation, scab, rust, white rot, ring spot, anthracnose, fusarium wilt, gray mold.
In the present composition, the content of active component depends on amount of application when being used alone, and also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc. by active component with liquid flux or solid carrier.According to different dosage form, in preparation, stabilizing agent known in those skilled in the art, antifreeze etc. can also be contained.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Composition comprises following component and content when making wetting powder: active components A 1% ~ 70%, active component B1% ~ 70%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
Composition comprises following component and content when making water dispersible granules: active components A 1% ~ 70%, active component B1% ~ 70%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component and content when making suspending agent: active components A 1% ~ 50%, active component B1% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making suspension emulsion: active components A 1% ~ 50%, active component B1% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making microemulsion: active components A 1% ~ 50%, active component B1% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making aqueous emulsion: active components A 1% ~ 50%, active component B1% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspending agent: active components A 1% ~ 50%, active component B1% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspension-suspendinagent agent: active components A 1% ~ 50%, active component B1% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that: (1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as downy mildew, late blight, early blight, phytophthora root rot, damping off, mottled rot disease, powdery mildew, banded sclerotial blight, rice blast, false smut, leaf spot, spot defoliation, scab, rust, white rot, ring spot, anthracnose, fusarium wilt, gray mold have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 18 wetting powder
By simeconazoles, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1.
The each component of table 1 embodiment 1 ~ 18 and content
Embodiment 19 ~ 35 water dispersible granules
Simeconazoles, active component B, dispersant, wetting agent, disintegrant, filler are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, obtaining water dispersible granules product of the present invention.Specifically in table 2.
The each component of table 2 embodiment 19 ~ 35 and content
Embodiment 36 ~ 52 suspending agent
Dispersant, wetting agent, thickener (can add and can not add), defoamer, antifreeze (can add and can not add) are mixed through high speed shear, add simeconazoles, active component B, surplus is supplied by deionized water, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent product of the present invention.Specifically in table 3.
The each component of table 3 embodiment 36 ~ 52 and content
Embodiment 53 ~ 59 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), deionized water are mixed through high speed shear, add simeconazoles, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained simeconazoles suspending agent, then by active component B, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 4.
The each component of table 4 embodiment 53 ~ 59 and content
Embodiment 60 ~ 73 aqueous emulsion
Simeconazoles, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 5.
The each component of table 5 embodiment 60 ~ 73 and content
Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, Flutriafol in table 1 to table 5 are exchanged, can novel formulation be obtained.
Embodiment 74 ~ 76 microemulsion
Simeconazoles, active component B are dissolved in and are equipped with in the homogenizer of solvent, emulsifier, antifreeze (can add and can not add), defoamer are joined in the homogenizer that above-mentioned solution is housed, give strong mixing after supplying surplus by deionized water and homogenize, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 6.
The each component of table 6 embodiment 74 ~ 76 and content
Embodiment 77 ~ 79 microcapsule suspending agent
By simeconazoles, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
The each component of table 7 embodiment 77 ~ 79 and content
Embodiment 80 ~ 82 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add simeconazoles, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 8.
The each component of table 8 embodiment 80 ~ 82 and content
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination; A is simeconazoles; B choosing is to the one in Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, Flutriafol.
Application Example two:
For examination disease: alternaria leaf spot of apple; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination simeconazoles and Original Tebuconazole and the two different ratio mixture.
Toxicity test result
Table 9 simeconazoles and the composite toxicity test analysis of results table to alternaria leaf spot of apple of Tebuconazole
As shown in Table 9, the proportioning of simeconazoles and the composite control alternaria leaf spot of apple of Tebuconazole is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, when the proportioning of simeconazoles and Tebuconazole is at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all greater than 2.20.Optimum ratio through test discovery simeconazoles and Tebuconazole is 30:1,25:1,20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,3:2,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, especially when simeconazoles and tebuconazole weight are more maximum than synergy ratio when being 1:1, synergistic effect is the most obvious.
Application Example three:
For examination disease: apple mildew; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination simeconazoles and the former medicine of own azoles alcohol and the two different ratio mixture.
Toxicity test result
Table 10 simeconazoles and the composite toxicity test analysis of results table to apple mildew of own azoles alcohol
As shown in Table 10, simeconazoles and the composite proportioning of preventing and treating apple mildew of own azoles alcohol are when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, when the proportioning of simeconazoles and own azoles alcohol is at 1 ︰ 20 ~ 30 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all greater than 2.20.Optimum ratio through test discovery simeconazoles and own azoles alcohol is 30:1,25:1,20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,3:2,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20, especially when simeconazoles and own azoles alcohol weight ratio are 3:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: pear scab; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination simeconazoles and difenoconazole technical material and the two different ratio mixture.
Toxicity test result
Table 11 simeconazoles and the composite toxicity test analysis of results table to pear scab of Difenoconazole
As shown in Table 11, the proportioning of simeconazoles and the composite control pear scab of Difenoconazole is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, when the proportioning of simeconazoles and Difenoconazole is at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all greater than 2.10.Optimum ratio through test discovery simeconazoles and Difenoconazole is 30:1,25:1,20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,3:2,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, especially when simeconazoles and Difenoconazole weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: grape powdery mildew; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination simeconazoles and the former medicine of penconazole and the two different ratio mixture.
Toxicity test result
Table 12 simeconazoles and the composite toxicity test analysis of results table to grape powdery mildew of penconazole
As shown in Table 12, the proportioning of simeconazoles and the composite control grape powdery mildew of penconazole is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, when the proportioning of simeconazoles and penconazole is at 1 ︰ 10 ~ 20 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all greater than 2.20.Optimum ratio through test discovery simeconazoles and penconazole is 20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,3:2,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10, especially when simeconazoles and penconazole weight ratio are 2:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For examination disease: rice blast; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination simeconazoles and propiconazole and the two different ratio mixture.
Toxicity test result
Table 13 simeconazoles and propiconazole compound are to the toxicity test analysis of results table of rice blast
As shown in Table 13, simeconazoles and propiconazole compound prevent and treat the proportioning of rice blast when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, when the proportioning of simeconazoles and propiconazole is at 1 ︰ 20 ~ 10 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all greater than 2.25.Optimum ratio through test discovery simeconazoles and propiconazole is 10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,2:3,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20, especially when simeconazoles and propiconazole weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven:
For examination disease: powdery mildew of cucumber; Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd.; Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination simeconazoles and the former medicine of Flutriafol and the two different ratio mixture.
Toxicity test result
Table 14 simeconazoles and the composite toxicity test analysis of results table to powdery mildew of cucumber of Flutriafol
As shown in Table 14, simeconazoles and the composite proportioning of preventing and treating powdery mildew of cucumber of Flutriafol are when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, when the proportioning of simeconazoles and Flutriafol is at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all greater than 2.15.Optimum ratio through test discovery simeconazoles and Flutriafol is 30:1,25:1,20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,2:3,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, especially when simeconazoles and Flutriafol weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: simeconazoles and active component B composite after have obvious synergistic effect to the control of downy mildew, late blight, early blight, phytophthora root rot, damping off, mottled rot disease, powdery mildew, banded sclerotial blight, rice blast, false smut, leaf spot, spot defoliation, scab, rust, white rot, ring spot, anthracnose, fusarium wilt, gray mold, synergy ratio is all more than 1.50.
Test of pesticide effectiveness part
Test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided.Contrast medicament: 20% simeconazoles suspending agent (autogamy), 80% tebuconazole water dispersible granule (commercial), 40% hexaconazole suspending agent (commercial), 10% difenoconazole water dispersible granule (commercial), 10% penconazole missible oil (commercial), 250 grams per liter propiconazole emulsifiable concentrates (commercial), 12.5% Flutriafol suspending agent (commercial).
Application Example eight simeconazoles and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
This test arrangement is at Shaanxi Province's Weinan City, and the investigation powdery mildew of cucumber state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 15 simeconazoles and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 15, simeconazoles and active component B composite after effectively can prevent and treat powdery mildew of cucumber, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, and can treat cucumber downy mildew, gray mold, fusarium wilt, damping off, after 14 days, control efficiency is up to more than 97%.In test scope of medication, target crop is had no adverse effects.
Application Example nine simeconazoles and active component B and the composite water prevention rice sheath blight test of pesticide effectiveness thereof
This test arrangement is in Hanzhong city, and the investigation rice sheath blight disease state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 16 simeconazoles and active component B and the composite water prevention rice sheath blight test of pesticide effectiveness thereof
As can be seen from Table 16, simeconazoles and active component B composite after can the effective water prevention rice sheath blight, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, and can treat rice blast, false smut, and after 14 days, control efficiency is up to more than 97%.In test scope of medication, target crop is had no adverse effects.
Application Example ten simeconazoles and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is in Xianyang, Shanxi province city, and the investigation pear scab state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 60 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 17 simeconazoles and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 17, simeconazoles and active component B composite after effectively can prevent and treat pear scab, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 simeconazoles and active component B and the composite control grape powdery mildew test of pesticide effectiveness thereof
This test arrangement is at weinan suburban area, and the investigation grape powdery mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 18 simeconazoles and active component B and the composite control grape powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 18, simeconazoles and active component B composite after effectively can prevent and treat grape powdery mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, and can treat fruit white rot of grape, downy mildew, gray mold, after 14 days, control efficiency is up to more than 97%.In test scope of medication, target crop is had no adverse effects.
Application Example 12 simeconazoles and active component B and compositely prevent and treat the wheat rust test of pesticide effectiveness
This test arrangement is at Shaanxi Province's Weinan City, and the investigation wheat rust state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 19 simeconazoles and active component B and compositely prevent and treat the wheat rust test of pesticide effectiveness
As can be seen from Table 19, simeconazoles and active component B composite after effectively can prevent and treat wheat rust, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, and can treat wheat powdery mildew, banded sclerotial blight, and after 14 days, control efficiency is up to more than 97%.In test scope of medication, target crop is had no adverse effects.
Application Example 13 simeconazoles and active component B and the composite control ornamental plants powdery mildew test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and the investigation ornamental plants powdery mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows: table 20 simeconazoles and active component B and the composite control ornamental plants powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 20, simeconazoles and active component B composite after can effectively prevent and treat ornamental plants powdery mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 14 simeconazoles and active component B and compositely prevent and treat the sigatoka test of pesticide effectiveness
This test arrangement is in Zhanjiang, Guangdong Province, and the investigation sigatoka state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 21 simeconazoles and active component B and compositely prevent and treat the sigatoka test of pesticide effectiveness
As can be seen from Table 21, simeconazoles and active component B composite after effectively can prevent and treat sigatoka, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, and can treat banana freckle, and after 14 days, control efficiency is up to more than 97%.In test scope of medication, target crop is had no adverse effects.
Application Example 15 simeconazoles and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This test arrangement is in Xianyang city, and the investigation alternaria leaf spot of apple state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after last dispenser 10 days, 30 days, 45 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 22 simeconazoles and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 22, simeconazoles and active component B composite after effectively can prevent and treat alternaria leaf spot of apple, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, and can treat apple anthracnose, ring spot, and after 14 days, control efficiency is up to more than 97%.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, simeconazoles and Tebuconazole, own azoles alcohol, Difenoconazole, penconazole, propiconazole, the composite rear preventive effect to Common Diseases such as the downy mildew in various crop, late blight, early blight, phytophthora root rot, damping off, mottled rot disease, powdery mildew, banded sclerotial blight, rice blast, false smut, leaf spot, spot defoliation, scab, rust, white rot, ring spot, anthracnose, fusarium wilt, gray molds of Flutriafol are all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. one kind contains the efficient bactericidal composite of simeconazoles and triazole type, it is characterized in that active ingredient is active components A and active component B, active components A and active component B weight ratio are 1 ︰ 70 ~ 70 ︰ 1, and described active components A is simeconazoles, and active component B is Tebuconazole.
2. the efficient bactericidal composite containing simeconazoles and triazole type according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1.
3. the efficient bactericidal composite containing simeconazoles and triazole type according to claim 2, is characterized in that: the weight ratio of simeconazoles and Tebuconazole is 1 ︰ 30 ~ 30 ︰ 1.
4., according to the efficient bactericidal composite containing simeconazoles and triazole type in claim 1 ~ 3 described in any one, it is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the efficient bactericidal composite containing simeconazoles and triazole type according to claim 4 is for preventing and treating the application of crop pest.
6. application according to claim 5, is characterized in that: described disease comprises downy mildew, late blight, early blight, phytophthora root rot, damping off, mottled rot disease, powdery mildew, banded sclerotial blight, rice blast, false smut, leaf spot, spot defoliation, scab, rust, white rot, ring spot, anthracnose, fusarium wilt, gray mold.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210294511.XA CN103583564B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
| CN201510770494.6A CN105410011B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210294511.XA CN103583564B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510770494.6A Division CN105410011B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103583564A CN103583564A (en) | 2014-02-19 |
| CN103583564B true CN103583564B (en) | 2016-01-13 |
Family
ID=50074054
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510770494.6A Active CN105410011B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
| CN201210294511.XA Expired - Fee Related CN103583564B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510770494.6A Active CN105410011B (en) | 2012-08-17 | 2012-08-17 | A kind of efficient bactericidal composite containing simeconazoles and triazole type |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN105410011B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107787984A (en) * | 2016-08-29 | 2018-03-13 | 上海生农生化制品有限公司 | A kind of prothioconazoles Tebuconazole micro-capsule suspension and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078444C (en) * | 1991-10-09 | 2002-01-30 | 三共株式会社 | Iungicidal silicon-contraining compounds, their preparation and their agrochemical and medicinal uses |
| CN102308808A (en) * | 2011-10-10 | 2012-01-11 | 海利尔药业集团股份有限公司 | Antibacterial composition containing cyflufenamid and triazole bactericides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3848530B2 (en) * | 1999-11-19 | 2006-11-22 | 三共アグロ株式会社 | Agricultural and horticultural sterilization composition |
| US7687434B2 (en) * | 2000-12-22 | 2010-03-30 | Monsanto Technology, Llc | Method of improving yield and vigor of plants |
| PL220326B1 (en) * | 2002-03-07 | 2015-10-30 | Basf Ag | Triazole-based fungicidal mixture, the method for controlling harmful fungi and the fungicide |
| BRPI1000361B1 (en) * | 2010-02-05 | 2017-04-11 | Rotam Agrochem Int Co Ltd | fungicidal composition, its use and methods for preventing and / or combating pathogen damage or pest damage in a plant |
| CN102246807B (en) * | 2011-07-21 | 2013-06-12 | 青岛奥迪斯生物科技有限公司 | Sterilization composition containing tetraconazole and simeconazole |
-
2012
- 2012-08-17 CN CN201510770494.6A patent/CN105410011B/en active Active
- 2012-08-17 CN CN201210294511.XA patent/CN103583564B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078444C (en) * | 1991-10-09 | 2002-01-30 | 三共株式会社 | Iungicidal silicon-contraining compounds, their preparation and their agrochemical and medicinal uses |
| CN102308808A (en) * | 2011-10-10 | 2012-01-11 | 海利尔药业集团股份有限公司 | Antibacterial composition containing cyflufenamid and triazole bactericides |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105410011B (en) | 2018-07-03 |
| CN103583564A (en) | 2014-02-19 |
| CN105410011A (en) | 2016-03-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103621512B (en) | A kind of high-efficient pesticide composition | |
| CN103518770B (en) | Bactericidal composition containing fluopyram and triazole | |
| CN102696666A (en) | High-efficiency bactericidal composition containing fenamidone and triazole | |
| CN104336048A (en) | Bactericidal composition containing fluorothiazolepyrithylone and triazoles | |
| CN103416425B (en) | A kind of bactericidal composition containing tiadinil and triazole type | |
| CN104222118B (en) | A kind of bactericidal composition | |
| CN103651389A (en) | High-efficiency bactericidal composition containing penthiopyrad and triazole | |
| CN104170828A (en) | Sterilization composition containing penflufen and triazole | |
| CN103583564B (en) | A kind of efficient bactericidal composite containing simeconazoles and triazole type | |
| CN103651413B (en) | The bactericidal composition of a kind of fluorine azoles Acibenzolar and triazole type | |
| CN103583561B (en) | A kind of bactericidal composition containing simeconazoles | |
| CN104206390B (en) | A kind of bactericidal composition containing triazolone | |
| CN103651425A (en) | Pesticide composition containing dimoxystrobin | |
| CN102027987B (en) | Metconazole-containing pesticide composition | |
| CN103749467A (en) | Sterilization composition containing metconazole | |
| CN103461343A (en) | Efficient sterilization composition containing fenamidone and triazole | |
| CN103583527B (en) | A kind of bactericidal composition containing Fenarimol and triazole type | |
| CN103444722A (en) | Sterilization composition containing quinoxyfen and triazole | |
| CN103444768A (en) | Efficient sterilization composition containing phenoxyquinoline and triazole | |
| CN103563908B (en) | A kind of efficient bactericidal composite containing bromuconazole | |
| CN103651415B (en) | Bactericidal composition containing fluorine azole activated ester and triazoles | |
| CN105076157A (en) | Bactericidal composition containing dimoxystrobin and triazoles | |
| CN103931656A (en) | Composition containing brevibacillus laterosporus and triazoles | |
| CN103563955B (en) | A kind of bactericidal composition containing bromuconazole | |
| CN103563994A (en) | Bactericidal composition containing simeconazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160113 Termination date: 20160817 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |