CN103566321A - Preparation method of Xiaochaihu decoction particles - Google Patents
Preparation method of Xiaochaihu decoction particles Download PDFInfo
- Publication number
- CN103566321A CN103566321A CN201210260622.9A CN201210260622A CN103566321A CN 103566321 A CN103566321 A CN 103566321A CN 201210260622 A CN201210260622 A CN 201210260622A CN 103566321 A CN103566321 A CN 103566321A
- Authority
- CN
- China
- Prior art keywords
- filtrate
- condensed
- preparation
- thick paste
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a preparation method of Xiaochaihu decoction particles. The Xiaochaihu decoction particles derives from the Xiaochaihu decoction and is prepared from 400-800 parts of radix bupleuri, 400-600 parts of pinellia ternate, 200-400 parts of root of large-flowered skullcap, 200-400 parts of ginseng, 200-400 parts of Chinese-date, 100-250 parts of licorice root and 50-200 parts of ginger. The Xiaochaihu decoction particles has the advantages of high effective component content, less impurities and stable quality.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of preparation method of Herba Sidae Rhombifoliae soup granule.
Background technology
Herba Sidae Rhombifoliae soup is used for treating Shaoyang disease as harmonizing prescription always.The feature of Shaoyang disease is exactly touchingly not heal, and is more common in the delay stage of disease.This situation is due to due to immune functional disorder to a great extent.In fact, a lot of diseases of Treated by Minor Decoction of Bupleurum are all relevant with immune disorder.Such as rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus (sle), tumor, anaphylactic disease and viral infection etc.In recent decades, the production of Chinese herbal medicine has realized mechanization and semi-mechanization to a certain degree.Chinese medicine is often considered to that active constituent content is low, impurity is many, quality is unstable, so medication is based upon on the basis of experience more, can not integrate with modern medicine.For addressing this problem, Chinese medicine must be walked the road of extraction and purification.The extraction of Chinese medicine comprises many unit operationss such as leaching, clarification, filtration and evaporation.
Summary of the invention
The object of the invention is to overcome that active constituent content is low, impurity is many, the unsettled deficiency of quality, a kind of preparation method of Herba Sidae Rhombifoliae soup granule is provided.
The present invention is that the solution that the problem of the above-mentioned proposition of solution adopts is:
Radix Bupleuri 400-800 part, Rhizoma Pinelliae 400-600 part, Radix Scutellariae, Radix Ginseng, each 200-400 part of Fructus Jujubae, Radix Glycyrrhizae 100-250 part, Rhizoma Zingiberis Recens 50-200 part.
1. Radix Bupleuri is decocted with water 2-3 time, each 1.5-3.5 hour, collecting decoction, filters, filtrate is condensed into surveys the clear paste that relative density is 1.10-1.20 under 60-65 ℃ of condition, cooling, adds ethanol and makes to reach 55-75% containing alcohol amount, stirs, standing, filter, obtain filtering residue and filtrate A.
2. the washing with alcohol of 50-90% 2-3 time for filtering residue, merges washing liquid and filtrate A, and recovery ethanol is also condensed into and under 40 ℃ of conditions, surveys the thick paste A that relative density is 1.30-1.35.
3. Radix Scutellariae, Radix Ginseng, Fructus Jujubae, Radix Glycyrrhizae are 50-95% alcoholic solution dipping 15-25 hour by percent by volume respectively, filter, and filtrate recycling ethanol, is condensed into thick paste B.
4. the Rhizoma Pinelliae, Rhizoma Zingiberis Recens are decocted with water 2-3 time, each 1.5-3.5 hour, collecting decoction, standing, filter, filtrate and thick paste A, B mix homogeneously, is further condensed into obtain the relative density thick paste that is 1.10-1.35.
5. gained thick paste is added fluid bed on the conventional adjuvant using to carry out pelletize, obtain granule of the present invention.
Preferably, 1. described step is that Radix Bupleuri is decocted with water 3 times, each 1.5-3.5 hour, and collecting decoction, filters, and filtrate is condensed into and under 60-65 ℃ of condition, surveys the clear paste that relative density is 1.15-1.17.
Described step amount of water is 1. respectively: 10 times of medical material amounts, for the second time 8 times of medical material amounts, for the third time 6 times of medical material amounts for the first time.
1. described step adds ethanol makes to reach 60% containing alcohol amount.
Described step is 60% washing with alcohol 3 times for filtering residue 2., merges washing liquid and filtrate A, and recovery ethanol is also condensed into and under 40 ℃ of conditions, surveys the thick paste that relative density is 1.30-1.32.
The advantage that the present invention has and good effect are that active constituent content is high, impurity is few, steady quality.
The specific embodiment
Below in conjunction with specific embodiment, the invention will be further described, but do not limit the present invention.
Embodiment 1
500 parts of Radix Bupleuri, 400 parts of the Rhizoma Pinelliaes, respectively 300 parts, Radix Scutellariae, Radix Ginseng, Fructus Jujubae, 150 parts, Radix Glycyrrhizae, 100 parts, Rhizoma Zingiberis Recens.
1. Radix Bupleuri is decocted with water 3 times, for the first time 10 times of medical material amounts, for the second time 8 times of medical material amounts, 6 times of medical material amounts for the third time, each 2.5 hours, collecting decoction, filter, filtrate is condensed into surveys the clear paste that relative density is 1.15-1.17 under 60-65 ℃ of condition, cooling, adds ethanol and makes to reach 65% containing alcohol amount, stir, standing, filter, obtain filtering residue and filtrate A.
2. 75% washing with alcohol 3 times for filtering residue, merges washing liquid and filtrate A, and recovery ethanol is also condensed into and under 40 ℃ of conditions, surveys the thick paste A that relative density is 1.30-1.32.
3. Radix Scutellariae, Radix Ginseng, Fructus Jujubae, Radix Glycyrrhizae are 50-95% alcoholic solution dipping 20 hours by percent by volume respectively, filter, and filtrate recycling ethanol, is condensed into thick paste B.
4. the Rhizoma Pinelliae, Rhizoma Zingiberis Recens are decocted with water 3 times, each 3 hours, collecting decoction, standing, filter, filtrate and thick paste A, B mix homogeneously, is further condensed into obtain the relative density thick paste that is 1.10-1.35.
5. gained thick paste is added fluid bed on the conventional adjuvant using to carry out pelletize, obtain granule of the present invention.
Embodiment 2
600 parts of Radix Bupleuri, 500 parts of the Rhizoma Pinelliaes, respectively 300 parts, Radix Scutellariae, Radix Ginseng, Fructus Jujubae, 150 parts, Radix Glycyrrhizae, 100 parts, Rhizoma Zingiberis Recens.
1. Radix Bupleuri is decocted with water 3 times, for the first time 10 times of medical material amounts, for the second time 8 times of medical material amounts, 6 times of medical material amounts for the third time, each 3 hours, collecting decoction, filter, filtrate is condensed into surveys the clear paste that relative density is 1.15-1.16 under 60-65 ℃ of condition, cooling, adds ethanol and makes to reach 75% containing alcohol amount, stir, standing, filter, obtain filtering residue and filtrate A.
2. 75% washing with alcohol 3 times for filtering residue, merges washing liquid and filtrate A, and recovery ethanol is also condensed into and under 40 ℃ of conditions, surveys the thick paste A that relative density is 1.31-1.32.
3. Radix Scutellariae, Radix Ginseng, Fructus Jujubae, Radix Glycyrrhizae are 50-75% alcoholic solution dipping 18 hours by percent by volume respectively, filter, and filtrate recycling ethanol, is condensed into thick paste B.
4. the Rhizoma Pinelliae, Rhizoma Zingiberis Recens are decocted with water 3 times, each 3.5 hours, collecting decoction, standing, filter, filtrate and thick paste A, B mix homogeneously, is further condensed into obtain the relative density thick paste that is 1.18-1.32.
5. gained thick paste is added fluid bed on the conventional adjuvant using to carry out pelletize, obtain granule of the present invention.
Claims (5)
1. a preparation method for Herba Sidae Rhombifoliae soup granule, its prescription is: Radix Bupleuri 400-800 part, Rhizoma Pinelliae 400-600 part, Radix Scutellariae, Radix Ginseng, each 200-400 part of Fructus Jujubae, Radix Glycyrrhizae 100-250 part, Rhizoma Zingiberis Recens 50-200 part.
Preparation method is as follows:
1. Radix Bupleuri is decocted with water 2-3 time, each 1.5-3.5 hour, collecting decoction, filters, filtrate is condensed into surveys the clear paste that relative density is 1.10-1.20 under 60-65 ℃ of condition, cooling, adds ethanol and makes to reach 55-75% containing alcohol amount, stirs, standing, filter, obtain filtering residue and filtrate A.
2. the washing with alcohol of 50-90% 2-3 time for filtering residue, merges washing liquid and filtrate A, and recovery ethanol is also condensed into and under 40 ℃ of conditions, surveys the thick paste A that relative density is 1.30-1.35.
3. Radix Scutellariae, Radix Ginseng, Fructus Jujubae, Radix Glycyrrhizae are 50-95% alcoholic solution dipping 15-25 hour by percent by volume respectively, filter, and filtrate recycling ethanol, is condensed into thick paste B.
4. the Rhizoma Pinelliae, Rhizoma Zingiberis Recens are decocted with water 2-3 time, each 1.5-3.5 hour, collecting decoction, standing, filter, filtrate and thick paste A, B mix homogeneously, is further condensed into obtain the relative density thick paste that is 1.10-1.35.
5. gained thick paste is added fluid bed on the conventional adjuvant using to carry out pelletize, obtain granule of the present invention.
2. the preparation method of a kind of Herba Sidae Rhombifoliae soup granule according to claim 1, it is characterized in that: 1. described step is that Radix Bupleuri is decocted with water 3 times each 1.5-3.5 hour, collecting decoction, filter, filtrate is condensed into and under 60-65 ℃ of condition, surveys the clear paste that relative density is 1.15-1.17.
3. the preparation method of a kind of Herba Sidae Rhombifoliae soup granule according to claim 1, is characterized in that: described step amount of water is 1. respectively: 10 times of medical material amounts, for the second time 8 times of medical material amounts, for the third time 6 times of medical material amounts for the first time.
4. the preparation method of a kind of Herba Sidae Rhombifoliae soup granule according to claim 1, is characterized in that: 1. described step adds ethanol makes to reach 60% containing alcohol amount.
5. the preparation method of a kind of Herba Sidae Rhombifoliae soup granule according to claim 1, it is characterized in that: described step is 60% washing with alcohol 3 times for filtering residue 2., merge washing liquid and filtrate A, reclaim ethanol and be condensed into and under 40 ℃ of conditions, survey the thick paste that relative density is 1.30-1.32.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210260622.9A CN103566321A (en) | 2012-07-25 | 2012-07-25 | Preparation method of Xiaochaihu decoction particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210260622.9A CN103566321A (en) | 2012-07-25 | 2012-07-25 | Preparation method of Xiaochaihu decoction particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103566321A true CN103566321A (en) | 2014-02-12 |
Family
ID=50039602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210260622.9A Pending CN103566321A (en) | 2012-07-25 | 2012-07-25 | Preparation method of Xiaochaihu decoction particles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103566321A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977391A (en) * | 2014-06-11 | 2014-08-13 | 云南云龙制药股份有限公司 | Preparation method and applications of bupleurum tenue capsule |
-
2012
- 2012-07-25 CN CN201210260622.9A patent/CN103566321A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977391A (en) * | 2014-06-11 | 2014-08-13 | 云南云龙制药股份有限公司 | Preparation method and applications of bupleurum tenue capsule |
| CN103977391B (en) * | 2014-06-11 | 2016-06-01 | 云南云龙制药股份有限公司 | The preparation method of a kind of Xiao chaihu capsule and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102579576A (en) | Preparation methods of Chuanxiongchatiao granule extracts and preparations thereof | |
| CN103301206A (en) | Integrated technology for unitedly extracting various effectives component of cistanche and manufacturing extract by classes | |
| CN105131062B (en) | A kind of preparation method of Baical Skullcap root P.E | |
| CN101961356B (en) | Method for extracting active ingredients from traditional Chinese medicinal materials by circular percolation quickly | |
| WO2016074333A1 (en) | Drug or health care product preventing or treating liver and kidney damage-related diseases and use thereof | |
| CN104224911A (en) | New radix salviae milliorrhizae extract and preparation thereof | |
| CN103520286A (en) | Extraction process of raw medicinal materials of exterior syndrome-relieving particles for children | |
| CN103316154A (en) | Preparation method of Huanglian Shangqing tablets | |
| CN103566321A (en) | Preparation method of Xiaochaihu decoction particles | |
| CN103566165A (en) | Process of exocarpium citri grandis tablets | |
| CN1298362C (en) | Compound Chinese medicine prepn for treating pulvic infection and its prepn process | |
| CN107496884A (en) | Xiao Chai Hu granules composition and preparation method thereof | |
| CN1689612B (en) | Liver disease treating particle and its production method | |
| CN103588836A (en) | Preparation method of raw medicine scutellaria baicalensis extracts for veterinary use | |
| CN1210054C (en) | Novel preparation method for ageratum zhengqi capsule | |
| CN103566332A (en) | Fabrication technology of chill cold particles | |
| CN1413711A (en) | Preparation technology of | |
| CN103566318A (en) | Preparation method of Huoxiangzhengqi capsule | |
| CN103877171A (en) | Preparation process for liver-protecting tablet | |
| CN107875368A (en) | A kind of preparation method for being used for pregnant woman and helping the health care Chinese medicine of Recovery | |
| CN1159326C (en) | Process of extracting tannic acid from Geranium wilfordii root and the use of the extractive | |
| CN108452012A (en) | The preparation method of sanhuang tablets, sanhuang pian Radix Scutellariae extractum powder | |
| CN103083558B (en) | Novel application of traditional Chinese medicine composition for treating cerebral infarction during acute stage and earlier restoration stage | |
| CN101869681A (en) | Jinji blood stasis removing pellet | |
| CN1954862B (en) | Syrup for treating headache |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140212 |