CN103550742A - 一种预防胃癌术后转移的中药 - Google Patents
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Abstract
本发明公开了一种预防胃癌术后转移的中药，属于中药技术领域，由下述原料制备而成：党参5-8、白术4-7、干姜3-6、柴胡2-4、香附2-5、木香2-5、鸡血藤2-5、当归5-8、枸杞子4-6、白芍4-6、八月札2-4、青皮3-6、薏苡仁4-6、麦冬2-6、扁豆4-6、玉竹2-6、猫爪草2-6、僵蚕2-4、海蛤壳2-4、夏枯草2-4。该药物均采用纯天然中草药，无毒副作用，助于胃癌术后的辅助治疗，利于肠胃系统的恢复，加入舒肝健脾、补气理气、养血温阳、清热养阴、软坚化痰的中药，既利于术后身体状况的恢复，又可预防预防胃癌术后转移。
Description
技术领域
本发明涉及一种预防胃癌术后转移的中药，属于中药技术领域。
背景技术
胃癌的发病人数为常见肿瘤发病人数的四分之一，死亡率占我国恶性肿瘤的23.03%，居于首位。但胃癌起病隐匿，早起常无特异性临床症状，病变发展较快，多数胃癌患者诊断明确时病情已经到了中晚期，故临床上进展期胃癌比较常见。但胃癌易复发、转移，对丧失了根治性手术机会及术后复发转移的晚期胃癌病人，放疗、化疗是最主要的治疗方法。而放化疗因其选择性差，对正常组织细胞和脏器常有较大毒副作用，降低患者机体免疫力，降低患者生存质量，因此，术后进行中药辅助治疗可以增强病人的免疫状态、改善物质代谢、减轻化疗的毒副作用。
发明内容
本发明提供了一种预防胃癌术后转移的中药，该药物均采用纯天然中草药，无毒副作用，疗效确切，能够有效预防胃癌手术后癌细胞转移，并且可以达到快速恢复术后身体状况的效果。
本发明解决技术问题所采取的技术方案是：
一种预防胃癌术后转移的中药，其特征是，由以下重量份的中药制成：
党参5-8、白术4-7、干姜3-6、柴胡2-4、香附2-5、木香2-5、鸡血藤2-5、当归5-8、枸杞子4-6、白芍4-6、八月札2-4、青皮3-6、薏苡仁4-6、麦冬2-6、扁豆4-6、玉竹2-6、猫爪草2-6、僵蚕2-4、海蛤壳2-4、夏枯草2-4。
优选的，由以下重量份的中药制成：
党参6、白术6、干姜3、柴胡3、香附4、木香4、鸡血藤3、当归6、枸杞子4、白芍4、八月札4、青皮4、薏苡仁5、麦冬6、扁豆4、玉竹4、猫爪草4、僵蚕3、海蛤壳3、夏枯草3。
配制及服用方法：
水煎服，每日一剂，每剂服2次， 5天为一疗程。
中医看来，胃癌患者的病情特征往往是虚实错杂，常用舒肝健脾、补气理气、养血温阳、清热养阴、软坚化痰等法。目前对于胃癌的治疗，一般情况下都会采取放疗、化疗或者手术切除的手段，放疗、化疗后或者手术切除后的胃癌患者，虽然切除了肿瘤部位，但是由于胃癌的高复发率和高转移率，还是需要进行巩固治疗，以健脾理气、活血祛瘀、清热解毒、温中和胃为主对术后的复发进行预防，同时可以达到快速恢复术后身体状况的效果。
各中药的药理作用：
党参：甘，平。归脾、肺经。功能主治：补中益气，健脾益肺。用于脾肺虚弱，气短心悸，食少便溏，虚喘咳嗽，内热消渴。
白术：苦、甘，温。归脾、胃经。功能主治：健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。
干姜：辛、热。归脾、胃、肾、心、肺经。功能主治：干姜温中散寒，回阳通脉，燥湿消痰。用于脘腹冷痛，呕吐泄泻，肢冷脉微，痰饮喘咳。
柴胡：苦，微寒。归肝、胆经。功能主治：和解表里，疏肝，升阳。用于感冒发热，寒热往来，胸胁胀痛，月经不调，子官脱垂，脱肛。
香附：辛、微苦、微甘，平。归肝、脾、三焦经。功能主治：行气解郁，调经止痛。用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，胸脘痞闷，寒疝腹痛，乳房胀痛，月经不调，经闭痛经。
木香：辛、苦，温。归脾、胃、大肠、三焦、胆经。功能主治：行气止痛，健脾消食。用于胸脘胀痛，泻痢后重，食积不消，不思饮食。煨木香实肠止泻。用于泄泻腹痛。
鸡血藤：苦、甘，温。归肝、肾经。功能主治：补血，活血，通络。用于月经不调，血虚萎黄，麻木瘫痪，风湿痹痛。
当归：甘、辛，温。归肝、心、脾经。功能主治：补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。
枸杞子：甘，平。归肝、肾经。功能主治：滋补肝肾，益精明目。用于虚劳精亏，腰膝酸痛，眩晕耳鸣，内热消渴，血虚萎黄，目昏不明。
白芍：苦、酸，微寒。归肝、脾经。功能主治：平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
八月札：昧微苦，性平。归肝、胃、膀胱经。肝；胃经。功能主治：疏肝和胃，活血止痛，软坚散结，利小便。主肝胃气滞，脘腹、胁助胀痛，饮食不消，下痢便泄，疝气疼痛，腰痛，经闭痛经，瘿瘤瘰疬，恶性肿瘤。
青皮：苦；辛；温，肝；胆；脾；肺；心经。功能主治：疏肝破气；消积化滞。主肝郁气滞之胁肋胀痛；乳房胀痛；乳核；乳痈；疝气疼痛；食积气滞之胃脘胀痛；以及气滞血瘀所至的症瘕积聚；久疟癖块。
薏苡仁：甘、淡，凉。归脾、胃、肺经。功能主治：健脾渗湿，除痹止泻，清热排浓。用于水肿，脚气，小便不利，湿痹拘挛，脾虚泄泻，肺痈，肠痈；扁平疣。
麦冬：甘，微苦，微寒。归心、肺、胃经。功能与主治：养阴生津，润肺清心。用于肺燥干咳。虚痨咳嗽，津伤口渴，心烦失眠，内热消渴，肠燥便秘；咽白喉。
扁豆：性味甘，平，入脾、胃经。功能主治：健脾和中，消暑化湿。治暑湿吐泻，脾虚呕逆，食少久泄，水停消渴，赤白带下，小儿疳积。
玉竹：甘，微寒。归肺、胃经。功能主治：养阴润燥，生津止渴。用于肺胃阴伤，燥热咳嗽，咽干口渴，内热消渴。
猫爪草：甘、辛，温。归肝、肺经。功能主治：散结，消肿。用于瘰疬未溃、淋巴结结核。
僵蚕：咸、辛，平。归肝、肺、胃经。功能主治：祛风定惊，化痰散结。用于惊风抽搐，咽喉肿痛，皮肤瘙痒，颌下淋巴结炎，面神经麻痹。
海蛤壳：咸，平。入心、肾经。功能主治：清热，利水，化痰，软坚。治热痰喘嗽，水肿，淋病，瘿、瘤，积聚，血结胸痛，血痢，痔疮，崩漏，带下。
夏枯草：辛、苦，寒。归肝、胆经。功能主治：清火，明目，散结，消肿。用于目赤肿痛，目珠夜痛，头痛眩晕，瘰疬，瘿瘤，乳痈肿痛；甲状腺肿大，淋巴结结核，乳腺增生，高血压。
本发明的有益效果是：本发明以天然的中药为原料，毒副作用小，采用具有健脾理气、活血祛瘀、清热解毒、温中和胃等功能的中草药组方，可以有效防止胃癌切除后的复发，同时可以达到术后恢复的效果。以本发明药物治疗缓解总有效率为98.3%。
中医看来，胃癌患者的病情特征往往是虚实错杂，常用舒肝健脾、补气理气、养血温阳、清热养阴、软坚化痰等法。目前对于胃癌的治疗，一般情况下都会采取放疗、化疗或者手术切除的手段，放疗、化疗后或者手术切除后的胃癌患者，虽然切除了肿瘤部位，但是由于胃癌的高复发率和高转移率，还是需要进行巩固治疗，以健脾理气、活血祛瘀、清热解毒、温中和胃为主对术后的复发进行预防，同时可以达到快速恢复术后身体状况的效果。
以下结合临床数据及典型病例来进一步说明其有益效果。
一、临床观察
1.临床资料：患者人数60人，均为胃癌患者，并且经过胃切除手术。年龄段34岁～65岁，平均年龄48岁，平均分为两组，每组30例，两组经统计学处理，其性别、年龄、病程、病情等无显著性差异（P>0.05），具有可比性。
2.诊断标准：术后1年后做B超或CT检查和胃镜检查。
3.治疗方法：
实验组：服用本发明所述的中药，所述用法及用量：每日2～3次，每次2～4粒。具体使用时间和使用剂量根据患者的身体情况确定。一年后观察效果。
对照组：不服用药物，正常生活。一年后观察效果。
4. 疗效评定标准：①有效：身体快速恢复，经B超或CT检查和胃镜检查未出现复发症状；②显效：身体逐渐恢复，出现轻微上述症状，长期服用后症状慢慢消失；③无效：检查出现复发现象，且较明显。
5.治疗结果：
实验组：有效50人，有效率83.3%，显效9人，有效率15%，无效1人，无效率1.7%，总有效率98.3%。也就是说实验组复发率为1.7%。
对照组：复发人数为10人，复发率为16.7%。
二、典型病例：
病例1，王某某，男，1958 年生。2007年10月做胃80%切除手术，手术成功，服用本发明的中药，每日一剂，服用上述中药。坚持服用，身体状况逐渐恢复，一年后并未出现复发现象。
病例2：林某某，女，1967年生。2008年12月进行胃全切手术，服用本发明的中药，每日一剂，服用上述中药。坚持服用，刚刚做完手术时，身体虚弱，饮食量较少，服用一个月后，身体状况逐渐恢复，继续服用，跟踪一年并未出现复发现象。
病例3，刘某某，男，1967年生。2008年6月进行胃70%切除手术，服用本发明的中药，每日一剂，服用上述中药。坚持服用，刚刚做完手术时，身体虚弱，卧床休息，服用一个月后，身体状况逐渐恢复，继续服用，跟踪一年并未出现复发现象。
具体实施方式
实施例1
配方：党参6、白术6、干姜3、柴胡3、香附4、木香4、鸡血藤3、当归6、枸杞子4、白芍4、八月札4、青皮4、薏苡仁5、麦冬6、扁豆4、玉竹4、猫爪草4、僵蚕3、海蛤壳3、夏枯草3。
实施例2
党参5、白术4、干姜6、柴胡2、香附3、木香5、鸡血藤4、当归8、枸杞子5、白芍5、八月札2、青皮2、薏苡仁6、麦冬4、扁豆6、玉竹3、猫爪草5、僵蚕4、海蛤壳2、夏枯草4。
实施例3：
党参8、白术4、干姜3、柴胡4、香附5、木香2、鸡血藤3、当归5、枸杞子6、白芍5、八月札3、青皮6、薏苡仁4、麦冬2、扁豆5、玉竹5、猫爪草6、僵蚕2、海蛤壳4、夏枯草2。
Claims (2)
1.一种预防胃癌术后转移的中药，其特征是，由以下重量份的中药制成：
党参5-8、白术4-7、干姜3-6、柴胡2-4、香附2-5、木香2-5、鸡血藤2-5、当归5-8、枸杞子4-6、白芍4-6、八月札2-4、青皮3-6、薏苡仁4-6、麦冬2-6、扁豆4-6、玉竹2-6、猫爪草2-6、僵蚕2-4、海蛤壳2-4、夏枯草2-4。
2.根据权利要求1所述的预防胃癌术后转移的中药，其特征是，由以下重量份的中药制成：
党参6、白术6、干姜3、柴胡3、香附4、木香4、鸡血藤3、当归6、枸杞子4、白芍4、八月札4、青皮4、薏苡仁5、麦冬6、扁豆4、玉竹4、猫爪草4、僵蚕3、海蛤壳3、夏枯草3。
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