CN103550723A - Traditional Chinese medicine preparation for treating Raynaud disease - Google Patents
Traditional Chinese medicine preparation for treating Raynaud disease Download PDFInfo
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- CN103550723A CN103550723A CN201310581354.5A CN201310581354A CN103550723A CN 103550723 A CN103550723 A CN 103550723A CN 201310581354 A CN201310581354 A CN 201310581354A CN 103550723 A CN103550723 A CN 103550723A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating Raynaud disease. The traditional Chinese medicine preparation is prepared from the following raw medicinal materials in parts by weight: 6-9 parts of fructus psoraleae, 6-12 parts of lily, 4-6 parts of sappanwood, 4-6 parts of curcuma zedoary, 10-20 parts of rheum officinale, 7-9 parts of the root of red-rooted salvia, 4-7 parts of trichosanthes kirilowii Maxim, 4-6 parts of kelp, 6-12 parts of honeysuckle, 4-6 parts of radix curcumae longae and 4-6 parts of prunella spike. A preparation method of the medicine is as follows: weighing the raw medicinal materials, decocting twice with water, combining the filtrate of the two processes, concentrating until the relative density is 1.02-1.05 (detected at 25 DEG C), thus obtaining the traditional Chinese medicine preparation. Through clinical verifications, the effective rate of the traditional Chinese medicine preparation for treating Raynaud disease is 62.7%; the traditional Chinese medicine preparation acts fast, has significant curative effect and is convenient to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of Raynaud disease.
Background technology
Raynaud disease, claims again Raynaud's disease, is a kind of with ictal finger (toe) end palor, livid purple then flushing, accompany by pain and paraesthesia, and recovering to be normally the dysfunction of blood vessel disease of feature, to mostly occur at 20~40 years old because of warm, women is more than male.During outbreak, brothers are cold, and numbness occasionally has pain.When outbreak typical case, take metacarpophalangeal joints as boundary, finger sends out cool, pale, blue, flushing then.Terminal stage of a disease, engenders that dorsal surfaces of fingers fine hair disappears, and nail growth is slack-off, coarse, distortion, atrophoderma attenuation and feeling nervous (scleroderma refers to), and finger tip or nail matrix form ulcer around, and can cause infection.
The cause of disease for Raynaud disease, completely not clear and definite yet at present, Chinese scholars is unanimously thought: cold stimulation, and neural excitation and endocrine dysfunction are its principal elements, wherein especially with sympathetic nerve, be overexcited, cause small artery contraction around to cause that finger (toe) end ischemia is common.In treatment, doctor trained in Western medicine adopts the operative treatment of regional Sympathectomy or SNE excision, and Drug therapy first-selection can weaken the medicine of sympathetic nerve conduction etc., but these method therapeutic effect are all not good, and treatment cost is higher.
Raynaud disease belongs to the traditional Chinese medical science " arthromyodynia " category, and main feature is that sering retardance is obstructed, and extremity are fainted contrary, its origin cause of formation is that human righteousness is first empty, YANG QI deficiency, interspaces of skin and muscles being loose, the exopathogen of easily having a cold is attacked, the evil Yong Sai sering of wind and cold poison, so that QI-blood circulation is not freely fallen ill.Though have a lot of Chinese traditional treatment methods at present, effect is all not ideal enough, need the better medicine of a kind of therapeutic effect.
Summary of the invention
For above-mentioned prior art, the invention provides the Chinese medicine preparation that a kind of therapeutic effect is better used for the treatment of Raynaud disease.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine preparation for the treatment of Raynaud disease, to be made by the crude drug of following weight portion: 6~9 parts of Fructus Psoraleaes, 6~12 parts of Bulbus Liliies, 4~6 parts of Lignum Sappans, 4~6 parts of Rhizoma Curcumae, 10~20 parts of Radix Et Rhizoma Rhei, 7~9 parts of Radix Salviae Miltiorrhizaes, 4~7 parts of Fructus Trichosanthis, 4~6 parts of Thallus Laminariae (Thallus Eckloniae)s, 6~12 parts of Flos Loniceraes, 4~6 parts, Rhizoma Curcumae Longae, 4~6 parts of Spica Prunellaes.
Preferably, be to be made by the crude drug of following weight portion: 6 parts of Fructus Psoraleaes, 10 parts of Bulbus Liliies, 6 parts of Lignum Sappans, 6 parts of Rhizoma Curcumae, 12 parts of Radix Et Rhizoma Rhei, 9 parts of Radix Salviae Miltiorrhizaes, 6 parts of Fructus Trichosanthis, 6 parts of Thallus Laminariae (Thallus Eckloniae)s, 9 parts of Flos Loniceraes, 6 parts, Rhizoma Curcumae Longae, 6 parts of Spica Prunellaes.
The preparation method of the Chinese medicine preparation of described treatment Raynaud disease is: press consumption proportion weighting raw materials, decoct with water twice, add for the first time 8 times of amounts (weight multiple) water, decoct 1.5~2h, filter, in filtering residue, add 6 times of amounts (weight multiple) water for the second time, decoct 1~2h, filter, merge filtrate twice, being concentrated into relative density is 1.02~1.05(25 ℃ of survey), must treat the Chinese medicine preparation of Raynaud disease, bottling, sealing, put shady and cool dry place, standby.
The Chinese medicine preparation for the treatment of Raynaud disease of the present invention, during use, gets l00ml, adds boiled water to 200ml, fumigation and wash method affected part, every day twice, each about 20 minutes.
The Chinese medicine preparation for the treatment of Raynaud disease of the present invention, has following effect:
(1) improve blood circulation and microcirculation, increase LBF amount, improve local organization nutrition.
(2) expansion peripheral vessels, removes vasospasm.
(3) there is anticoagulant, antithrombotic and fibrinolysis activity.
(4) blood fat reducing and promotion atheromatous plaque disappear.
(5) antiinflammatory is analgesic, promotes inflammation to absorb.
(6) promote the softening of proliferative lesion and disappear.
(7) promote tissue repair, make wound healing.
The medicine preparation for the treatment of Raynaud disease of the present invention, through clinical verification, obvious effective rate 62.7%, instant effect, good effect, easy to use.
The specific embodiment
Below in conjunction with embodiment and clinical data, the present invention is further illustrated.
A kind of Chinese medicine preparation for the treatment of Raynaud disease of embodiment 1 preparation
Formula is: Fructus Psoraleae 600g, Bulbus Lilii 1000g, Lignum Sappan 600g, Rhizoma Curcumae 600g, Radix Et Rhizoma Rhei 1200g, Radix Salviae Miltiorrhizae 900g, Fructus Trichosanthis 600g, Thallus Laminariae (Thallus Eckloniae) 600g, Flos Lonicerae 900g, Rhizoma Curcumae Longae 600g, Spica Prunellae 600g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decoct 2h, double gauze filters, and adds for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, being concentrated into relative density is 1.05(25 ℃ of survey), bottling, every bottle is 200ml, sealing, put shady and cool dry place, standby.
A kind of Chinese medicine preparation for the treatment of Raynaud disease of embodiment 2 preparation
Formula is: Fructus Psoraleae 6g, Bulbus Lilii 12g, Lignum Sappan 4g, Rhizoma Curcumae 6g, Radix Et Rhizoma Rhei 10g, Radix Salviae Miltiorrhizae 9g, Fructus Trichosanthis 4g, Thallus Laminariae (Thallus Eckloniae) 6g, Flos Lonicerae 6g, Rhizoma Curcumae Longae 6g, Spica Prunellae 4g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decocts 2h, and double gauze filters, add for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, being concentrated into relative density is 1.05(25 ℃ of survey), sealing, puts shady and cool dry place, standby.
A kind of Chinese medicine preparation for the treatment of Raynaud disease of embodiment 3 preparation
Formula is: Fructus Psoraleae 9g, Bulbus Lilii 6g, Lignum Sappan 6g, Rhizoma Curcumae 4g, Radix Et Rhizoma Rhei 20g, Radix Salviae Miltiorrhizae 7g, Fructus Trichosanthis 7g, Thallus Laminariae (Thallus Eckloniae) 4g, Flos Lonicerae 12g, Rhizoma Curcumae Longae 4g, Spica Prunellae 6g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decocts 2h, and double gauze filters, add for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, being concentrated into relative density is 1.05(25 ℃ of survey), sealing, puts shady and cool dry place, standby.
The clinical observation of clinical data Drug therapy Raynaud disease of the present invention
Patient's data: Raynaud disease 83 examples, male 15 examples, female's 68 examples, 1 year above 38 example of the course of disease, 3 years above 45 examples; Women is above women of 4O year, and women all has aggravation history after menoxenia and cold stimulation.
Therapeutic scheme: during use, get the medicine of l00ml embodiment 1 preparation, add boiled water to 200ml, fumigation and wash method affected part, twice of every day (each consumption is 1 medicine prepared by 100ml embodiment), each about 20 minutes.Treatment January after observe the curative effect.
Therapeutic outcome: learn according to Pei Yu elder brother < < peripheral vessels the criterion of therapeutical effect of drafting in > > therapeutic outcome is added up, result is: effective 52 examples, effective 29 examples, invalid 2 examples, obvious effective rate 62.7%.
Claims (3)
1. a Chinese medicine preparation for the treatment of Raynaud disease, it is characterized in that: be to be made by the crude drug of following weight portion: 6~9 parts of Fructus Psoraleaes, 6~12 parts of Bulbus Liliies, 4~6 parts of Lignum Sappans, 4~6 parts of Rhizoma Curcumae, 10~20 parts of Radix Et Rhizoma Rhei, 7~9 parts of Radix Salviae Miltiorrhizaes, 4~7 parts of Fructus Trichosanthis, 4~6 parts of Thallus Laminariae (Thallus Eckloniae)s, 6~12 parts of Flos Loniceraes, 4~6 parts, Rhizoma Curcumae Longae, 4~6 parts of Spica Prunellaes.
2. a kind of Chinese medicine preparation for the treatment of Raynaud disease according to claim 1, it is characterized in that: be to be made by the crude drug of following weight portion: 6 parts of Fructus Psoraleaes, 10 parts of Bulbus Liliies, 6 parts of Lignum Sappans, 6 parts of Rhizoma Curcumae, 12 parts of Radix Et Rhizoma Rhei, 9 parts of Radix Salviae Miltiorrhizaes, 6 parts of Fructus Trichosanthis, 6 parts of Thallus Laminariae (Thallus Eckloniae)s, 9 parts of Flos Loniceraes, 6 parts, Rhizoma Curcumae Longae, 6 parts of Spica Prunellaes.
3. a kind of preparation method for the treatment of the Chinese medicine preparation of Raynaud disease described in claim 1,2, it is characterized in that: press consumption proportion weighting raw materials, decoct with water twice, add for the first time 8 times of amounts (weight multiple) water, decoct 1.5~2h, filter, in filtering residue, add 6 times of amounts (weight multiple) water for the second time, decoct 1~2h, filter, merge filtrate twice, being concentrated into relative density is 1.02~1.05(25 ℃ of survey), must treat the Chinese medicine preparation of Raynaud disease.
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Cited By (1)
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CN106177161A (en) * | 2016-08-22 | 2016-12-07 | 吴斌 | A kind of medicine for treating raynaud disease |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1569116A (en) * | 2004-05-13 | 2005-01-26 | 哈尔滨康信药物技术开发有限公司 | Angitis treating medicine |
CN101269141A (en) * | 2008-05-08 | 2008-09-24 | 北京天科仁祥医药科技有限公司 | Chinese medicinal composition for treating raynaud's disease and preparation method thereof |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1569116A (en) * | 2004-05-13 | 2005-01-26 | 哈尔滨康信药物技术开发有限公司 | Angitis treating medicine |
CN101269141A (en) * | 2008-05-08 | 2008-09-24 | 北京天科仁祥医药科技有限公司 | Chinese medicinal composition for treating raynaud's disease and preparation method thereof |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106177161A (en) * | 2016-08-22 | 2016-12-07 | 吴斌 | A kind of medicine for treating raynaud disease |
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